Peritoneal dialysis reduces amyloid-beta plasma levels in humans and attenuates Alzheimer-associated phenotypes in an APP/PS1 mouse model

Acta Neuropathologica

Volumn 134, Issue 2, 2017, Pages 207-220

  Jin, Wang Sheng ^a   Shen, Lin Lin ^a   Bu, Xian Le ^a   Zhang, Wei Wei ^a   Chen, Si Han ^a   Huang, Zhi Lin ^b   Xiong, Jia Xiang ^c   Gao, Chang Yue ^a   Dong, Zhifang ^b   He, Ya Ni ^a   Hu, Zhi An ^c   Zhou, Hua Dong ^a   Song, Weihong ^d   Zhou, Xin Fu ^e   Wang, Yi Zheng ^f   Wang, Yan Jiang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^f INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Alzheimer s disease; Amyloid beta; Neurodegeneration; Peripheral clearance; Peritoneal dialysis

Indexed keywords

AMYLOID BETA PROTEIN; AIF1 PROTEIN, HUMAN; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; DNA BINDING PROTEIN; NERVE PROTEIN; PRESENILIN 1; SECRETASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLIA; HUMAN; INTERSTITIAL FLUID; LONG TERM POTENTIATION; MICRODIALYSIS; MOUSE; MOUSE MODEL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PERITONEAL DIALYSIS; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ANIMAL; APOPTOSIS; BLOOD; BRAIN; CASE CONTROL STUDY; COGNITIVE DEFECT; DISEASE MODEL; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOPTOSIS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CASE-CONTROL STUDIES; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PERITONEAL DIALYSIS; PHENOTYPE; PRESENILIN-1; RENAL INSUFFICIENCY, CHRONIC;

EID: 85018790640     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-017-1721-y     Document Type: Article

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