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Volumn 69, Issue 5, 2017, Pages 996-1008

Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain

Author keywords

[No Author keywords available]

Indexed keywords

17(R) HYDROXY DOCOSAHEXAENOIC ACID; ARACHIDONATE 15 LIPOXYGENASE; CHEMOKINE LIKE RECEPTOR 1; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPID; MESSENGER RNA; PROTEIN; PROTEIN ALX; RESOLVIN D2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 17-HYDROXY-4,7,10,13,15,19-DOCOSAHEXAENOIC ACID; CHEMOKINE RECEPTOR; CMKLR1 PROTEIN, HUMAN; CMKLR1 PROTEIN, RAT; ENZYME INHIBITOR; HSH2D PROTEIN, HUMAN; IODOACETIC ACID; LIPOXIN A(4) RECEPTOR, RAT; LIPOXIN RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 85018718620     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.40001     Document Type: Article
Times cited : (40)

References (49)
  • 2
    • 84891747397 scopus 로고    scopus 로고
    • The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?
    • Karsdal MA, Bay-Jensen AC, Lories RJ, Abramson S, Spector T, Pastoureau P, et al. The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments? Ann Rheum Dis 2014;73:336–48.
    • (2014) Ann Rheum Dis , vol.73 , pp. 336-348
    • Karsdal, M.A.1    Bay-Jensen, A.C.2    Lories, R.J.3    Abramson, S.4    Spector, T.5    Pastoureau, P.6
  • 3
    • 84871099014 scopus 로고    scopus 로고
    • Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
    • Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2197–223.
    • (2012) Lancet , vol.380 , pp. 2197-2223
    • Murray, C.J.1    Vos, T.2    Lozano, R.3    Naghavi, M.4    Flaxman, A.D.5    Michaud, C.6
  • 5
    • 84934437916 scopus 로고    scopus 로고
    • Altered central sensitization and pain modulation in the CNS in chronic joint pain
    • Arendt-Nielsen L, Skou ST, Nielsen TA, Petersen KK. Altered central sensitization and pain modulation in the CNS in chronic joint pain. Curr Osteoporos Rep 2015;13:225–34.
    • (2015) Curr Osteoporos Rep , vol.13 , pp. 225-234
    • Arendt-Nielsen, L.1    Skou, S.T.2    Nielsen, T.A.3    Petersen, K.K.4
  • 6
    • 84857863818 scopus 로고    scopus 로고
    • Rationing of total knee replacement: a cost-effectiveness analysis on a large trial data set
    • Dakin H, Gray A, Fitzpatrick R, Maclennan G, Murray D, the KAT Trial Group. Rationing of total knee replacement: a cost-effectiveness analysis on a large trial data set. BMJ Open 2012;2:e000332.
    • (2012) BMJ Open , vol.2
    • Dakin, H.1    Gray, A.2    Fitzpatrick, R.3    Maclennan, G.4    Murray, D.5
  • 7
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002;196:1025–37.
    • (2002) J Exp Med , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3    Colgan, S.P.4    Devchand, P.R.5    Mirick, G.6
  • 8
    • 0034675852 scopus 로고    scopus 로고
    • Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
    • Serhan CN, Clish CB, Brannon J, Colgan SP, Chiang N, Gronert K. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J Exp Med 2000;192:1197–204.
    • (2000) J Exp Med , vol.192 , pp. 1197-1204
    • Serhan, C.N.1    Clish, C.B.2    Brannon, J.3    Colgan, S.P.4    Chiang, N.5    Gronert, K.6
  • 11
    • 84860250554 scopus 로고    scopus 로고
    • Infection regulates pro-resolving mediators that lower antibiotic requirements
    • Chiang N, Fredman G, Backhed F, Oh SF, Vickery T, Schmidt BA, et al. Infection regulates pro-resolving mediators that lower antibiotic requirements. Nature 2012;484:524–8.
    • (2012) Nature , vol.484 , pp. 524-528
    • Chiang, N.1    Fredman, G.2    Backhed, F.3    Oh, S.F.4    Vickery, T.5    Schmidt, B.A.6
  • 12
    • 12344321136 scopus 로고    scopus 로고
    • Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
    • Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, et al. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med 2005;201:713–22.
    • (2005) J Exp Med , vol.201 , pp. 713-722
    • Arita, M.1    Bianchini, F.2    Aliberti, J.3    Sher, A.4    Chiang, N.5    Hong, S.6
  • 13
    • 33947269798 scopus 로고    scopus 로고
    • Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23
    • Arita M, Ohira T, Sun YP, Elangovan S, Chiang N, Serhan CN. Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23. J Immunol 2007;178:3912–7.
    • (2007) J Immunol , vol.178 , pp. 3912-3917
    • Arita, M.1    Ohira, T.2    Sun, Y.P.3    Elangovan, S.4    Chiang, N.5    Serhan, C.N.6
  • 14
    • 79955670124 scopus 로고    scopus 로고
    • Resolvins and protectins in inflammation resolution
    • Serhan CN, Petasis NA. Resolvins and protectins in inflammation resolution. Chem Rev 2011;111:5922–43.
    • (2011) Chem Rev , vol.111 , pp. 5922-5943
    • Serhan, C.N.1    Petasis, N.A.2
  • 15
    • 82455192824 scopus 로고    scopus 로고
    • Emerging roles of resolvins in the resolution of inflammation and pain
    • Ji RR, Xu ZZ, Strichartz G, Serhan CN. Emerging roles of resolvins in the resolution of inflammation and pain. Trends Neurosci 2011;34:599–609.
    • (2011) Trends Neurosci , vol.34 , pp. 599-609
    • Ji, R.R.1    Xu, Z.Z.2    Strichartz, G.3    Serhan, C.N.4
  • 16
    • 84899503421 scopus 로고    scopus 로고
    • Resolvins: endogenously-generated potent painkilling substances and their therapeutic perspectives
    • Sungjae Yoo, Lim JY, Hwang SW. Resolvins: endogenously-generated potent painkilling substances and their therapeutic perspectives. Curr Neuropharmacol 2013;11:664–76.
    • (2013) Curr Neuropharmacol , vol.11 , pp. 664-676
    • Yoo, S.1    Lim, J.Y.2    Hwang, S.W.3
  • 17
    • 80051953486 scopus 로고    scopus 로고
    • The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats
    • Lima-Garcia JF, Dutra RC, da Silva K, Motta EM, Campos MM, Calixto JB. The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats. Br J Pharmacol 2011;164:278–93.
    • (2011) Br J Pharmacol , vol.164 , pp. 278-293
    • Lima-Garcia, J.F.1    Dutra, R.C.2    da Silva, K.3    Motta, E.M.4    Campos, M.M.5    Calixto, J.B.6
  • 18
    • 77956321337 scopus 로고    scopus 로고
    • Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception
    • Bang S, Yoo S, Yang TJ, Cho H, Kim YG, Hwang SW. Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception. Br J Pharmacol 2010;161:707–20.
    • (2010) Br J Pharmacol , vol.161 , pp. 707-720
    • Bang, S.1    Yoo, S.2    Yang, T.J.3    Cho, H.4    Kim, Y.G.5    Hwang, S.W.6
  • 19
    • 84855679839 scopus 로고    scopus 로고
    • 17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception
    • Bang S, Yoo S, Yang TJ, Cho H, Hwang SW. 17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception. Br J Pharmacol 2012;165:683–92.
    • (2012) Br J Pharmacol , vol.165 , pp. 683-692
    • Bang, S.1    Yoo, S.2    Yang, T.J.3    Cho, H.4    Hwang, S.W.5
  • 20
    • 84874645504 scopus 로고    scopus 로고
    • Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury
    • Xu ZZ, Berta T, Ji RR. Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury. J Neuroimmune Pharmacol 2012;8:37–41.
    • (2012) J Neuroimmune Pharmacol , vol.8 , pp. 37-41
    • Xu, Z.Z.1    Berta, T.2    Ji, R.R.3
  • 21
    • 77952237425 scopus 로고    scopus 로고
    • Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
    • Xu ZZ, Zhang L, Liu T, Park JY, Berta T, Yang R, et al. Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med 2010;16:592–7.
    • (2010) Nat Med , vol.16 , pp. 592-597
    • Xu, Z.Z.1    Zhang, L.2    Liu, T.3    Park, J.Y.4    Berta, T.5    Yang, R.6
  • 22
    • 84884547336 scopus 로고    scopus 로고
    • Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release
    • Abdelmoaty S, Wigerblad G, Bas DB, Codeluppi S, Fernandez-Zafra T, El-Awady el-S, et al. Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release. PloS One 2013;8:e75543.
    • (2013) PloS One , vol.8
    • Abdelmoaty, S.1    Wigerblad, G.2    Bas, D.B.3    Codeluppi, S.4    Fernandez-Zafra, T.5    El-Awady, S.6
  • 23
    • 84871657834 scopus 로고    scopus 로고
    • Resolvin D1 reverses chronic pancreatitis-induced mechanical allodynia, phosphorylation of NMDA receptors, and cytokines expression in the thoracic spinal dorsal horn
    • Feng QX, Feng F, Feng XY, Li SJ, Wang SQ, Liu ZX, et al. Resolvin D1 reverses chronic pancreatitis-induced mechanical allodynia, phosphorylation of NMDA receptors, and cytokines expression in the thoracic spinal dorsal horn. BMC Gastroenterol 2012;12:148.
    • (2012) BMC Gastroenterol , vol.12 , pp. 148
    • Feng, Q.X.1    Feng, F.2    Feng, X.Y.3    Li, S.J.4    Wang, S.Q.5    Liu, Z.X.6
  • 24
    • 84907222918 scopus 로고    scopus 로고
    • Protective actions of aspirin-triggered (17R) resolvin D1 and its analogue, 17R-hydroxy-19-para-fluorophenoxy-resolvin D1 methyl ester, in C5a-dependent IgG immune complex-induced inflammation and lung injury
    • Tang H, Liu Y, Yan C, Petasis NA, Serhan CN, Gao H. Protective actions of aspirin-triggered (17R) resolvin D1 and its analogue, 17R-hydroxy-19-para-fluorophenoxy-resolvin D1 methyl ester, in C5a-dependent IgG immune complex-induced inflammation and lung injury. J Immunol 2014;193:3769–78.
    • (2014) J Immunol , vol.193 , pp. 3769-3778
    • Tang, H.1    Liu, Y.2    Yan, C.3    Petasis, N.A.4    Serhan, C.N.5    Gao, H.6
  • 25
    • 81155138320 scopus 로고    scopus 로고
    • The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain
    • Sagar DR, Burston JJ, Hathway GJ, Woodhams SG, Pearson RG, Bennett AJ, et al. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. Mol Pain 2011;7:88.
    • (2011) Mol Pain , vol.7 , pp. 88
    • Sagar, D.R.1    Burston, J.J.2    Hathway, G.J.3    Woodhams, S.G.4    Pearson, R.G.5    Bennett, A.J.6
  • 26
    • 84882680194 scopus 로고    scopus 로고
    • Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis
    • Mapp PI, Sagar DR, Ashraf S, Burston JJ, Suri S, Chapman V, et al. Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. Osteoarthritis Cartilage 2013;21:1336–45.
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 1336-1345
    • Mapp, P.I.1    Sagar, D.R.2    Ashraf, S.3    Burston, J.J.4    Suri, S.5    Chapman, V.6
  • 27
    • 84929706995 scopus 로고    scopus 로고
    • Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat
    • Sagar DR, Nwosu L, Walsh DA, Chapman V. Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. Osteoarthritis Cartilage 2015;23:906–13.
    • (2015) Osteoarthritis Cartilage , vol.23 , pp. 906-913
    • Sagar, D.R.1    Nwosu, L.2    Walsh, D.A.3    Chapman, V.4
  • 28
    • 34447542248 scopus 로고    scopus 로고
    • Prenatal exposure to a low protein diet programmes disordered regulation of lipid metabolism in the ageing rat
    • Erhuma A, Salter AM, Sculley DV, Langley-Evans SC, Bennett A. Prenatal exposure to a low protein diet programmes disordered regulation of lipid metabolism in the ageing rat. Am J Physiol Endocrinol Metab 2007;292:1702–14.
    • (2007) Am J Physiol Endocrinol Metab , vol.292 , pp. 1702-1714
    • Erhuma, A.1    Salter, A.M.2    Sculley, D.V.3    Langley-Evans, S.C.4    Bennett, A.5
  • 29
    • 84903896382 scopus 로고    scopus 로고
    • Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis
    • Sagar DR, Ashraf S, Xu L, Burston JJ, Menhinick MR, Poulter CL, et al. Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis. Ann Rheum Dis 2014;73:1558–65.
    • (2014) Ann Rheum Dis , vol.73 , pp. 1558-1565
    • Sagar, D.R.1    Ashraf, S.2    Xu, L.3    Burston, J.J.4    Menhinick, M.R.5    Poulter, C.L.6
  • 30
    • 84882724897 scopus 로고    scopus 로고
    • The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study
    • Shimura Y, Kurosawa H, Sugawara Y, Tsuchiya M, Sawa M, Kaneko H, et al. The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study. Osteoarthritis Cartilage 2013;21:1179–84.
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 1179-1184
    • Shimura, Y.1    Kurosawa, H.2    Sugawara, Y.3    Tsuchiya, M.4    Sawa, M.5    Kaneko, H.6
  • 31
    • 34547843666 scopus 로고    scopus 로고
    • Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone
    • Hulejova H, Baresova V, Klezl Z, Polanska M, Adam M, Senolt L. Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone. Cytokine 2007;38:151–6.
    • (2007) Cytokine , vol.38 , pp. 151-156
    • Hulejova, H.1    Baresova, V.2    Klezl, Z.3    Polanska, M.4    Adam, M.5    Senolt, L.6
  • 32
    • 0027193338 scopus 로고
    • Elevated synovial fluid levels of interleukin-6 and tumor necrosis factor associated with early experimental canine osteoarthritis
    • Venn G, Nietfeld JJ, Duits AJ, Brennan FM, Arner E, Covington M, et al. Elevated synovial fluid levels of interleukin-6 and tumor necrosis factor associated with early experimental canine osteoarthritis. Arthritis Rheum 1993;36:819–26.
    • (1993) Arthritis Rheum , vol.36 , pp. 819-826
    • Venn, G.1    Nietfeld, J.J.2    Duits, A.J.3    Brennan, F.M.4    Arner, E.5    Covington, M.6
  • 33
    • 55349126753 scopus 로고    scopus 로고
    • Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis
    • Alvarez-Soria MA, Herrero-Beaumont G, Moreno-Rubio J, Calvo E, Santillana J, Egido J, et al. Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis. Osteoarthritis Cartilage 2008;16:1484–93.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1484-1493
    • Alvarez-Soria, M.A.1    Herrero-Beaumont, G.2    Moreno-Rubio, J.3    Calvo, E.4    Santillana, J.5    Egido, J.6
  • 34
    • 24344444571 scopus 로고    scopus 로고
    • Lipoxin A4 biology in the human synovium: role of the ALX signaling pathways in modulation of inflammatory arthritis
    • Fiore S, Antico G, Aloman M, Sodin-Semrl S. Lipoxin A4 biology in the human synovium: role of the ALX signaling pathways in modulation of inflammatory arthritis. Prostaglandins Leukot Essent Fatty Acids 2005;73:189–96.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 189-196
    • Fiore, S.1    Antico, G.2    Aloman, M.3    Sodin-Semrl, S.4
  • 35
    • 0242552331 scopus 로고    scopus 로고
    • Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis
    • Guzman RE, Evans MG, Bove S, Morenko B, Kilgore K. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis. Toxicol Pathol 2003;31:619–24.
    • (2003) Toxicol Pathol , vol.31 , pp. 619-624
    • Guzman, R.E.1    Evans, M.G.2    Bove, S.3    Morenko, B.4    Kilgore, K.5
  • 36
    • 0036793151 scopus 로고    scopus 로고
    • Induction of osteoarthritis in the rat by surgical tear of the meniscus: inhibition of joint damage by a matrix metalloproteinase inhibitor
    • Janusz MJ, Bendele AM, Brown KK, Taiwo YO, Hsieh L, Heitmeyer SA. Induction of osteoarthritis in the rat by surgical tear of the meniscus: inhibition of joint damage by a matrix metalloproteinase inhibitor. Osteoarthritis Cartilage 2002;10:785–91.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 785-791
    • Janusz, M.J.1    Bendele, A.M.2    Brown, K.K.3    Taiwo, Y.O.4    Hsieh, L.5    Heitmeyer, S.A.6
  • 37
    • 33847410500 scopus 로고    scopus 로고
    • Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain
    • Beyreuther B, Callizot N, Stohr T. Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. Arthritis Res Ther 2007;9:R14.
    • (2007) Arthritis Res Ther , vol.9 , pp. R14
    • Beyreuther, B.1    Callizot, N.2    Stohr, T.3
  • 38
    • 57349138458 scopus 로고    scopus 로고
    • An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption
    • Herrera BS, Ohira T, Gao L, Omori K, Yang R, Zhu M, et al. An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption. Br J Pharmacol 2008;155:1214–23.
    • (2008) Br J Pharmacol , vol.155 , pp. 1214-1223
    • Herrera, B.S.1    Ohira, T.2    Gao, L.3    Omori, K.4    Yang, R.5    Zhu, M.6
  • 40
    • 33644928418 scopus 로고    scopus 로고
    • RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis
    • Hasturk H, Kantarci A, Ohira T, Arita M, Ebrahimi N, Chiang N, et al. RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis. FASEB J 2006;20:401–3.
    • (2006) FASEB J , vol.20 , pp. 401-403
    • Hasturk, H.1    Kantarci, A.2    Ohira, T.3    Arita, M.4    Ebrahimi, N.5    Chiang, N.6
  • 41
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: neurons, immune cells and glia
    • Scholz J, Woolf CJ. The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci 2007;10:1361–8.
    • (2007) Nat Neurosci , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 42
    • 84945271640 scopus 로고    scopus 로고
    • Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice: potential role of TRPA1 in osteoarthritis
    • Moilanen LJ, Hamalainen M, Nummenmaa E, Ilmarinen P, Vuolteenaho K, Nieminen RM, et al. Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice: potential role of TRPA1 in osteoarthritis. Osteoarthritis Cartilage 2015;23:2017–26.
    • (2015) Osteoarthritis Cartilage , vol.23 , pp. 2017-2026
    • Moilanen, L.J.1    Hamalainen, M.2    Nummenmaa, E.3    Ilmarinen, P.4    Vuolteenaho, K.5    Nieminen, R.M.6
  • 43
    • 84965062058 scopus 로고    scopus 로고
    • The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1
    • Shutov LP, Warwick CA, Shi X, Gnanasekaran A, Shepherd AJ, Mohapatra DP, et al. The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1. J Neurosci 2016;36:5055–70.
    • (2016) J Neurosci , vol.36 , pp. 5055-5070
    • Shutov, L.P.1    Warwick, C.A.2    Shi, X.3    Gnanasekaran, A.4    Shepherd, A.J.5    Mohapatra, D.P.6
  • 44
    • 77957056575 scopus 로고    scopus 로고
    • Targeting astrocyte signaling for chronic pain
    • Gao YJ, Ji RR. Targeting astrocyte signaling for chronic pain. Neurotherapeutics 2010;7:482–93.
    • (2010) Neurotherapeutics , vol.7 , pp. 482-493
    • Gao, Y.J.1    Ji, R.R.2
  • 45
    • 84888637560 scopus 로고    scopus 로고
    • Glia and pain: is chronic pain a gliopathy?
    • Ji RR, Berta T, Nedergaard M. Glia and pain: is chronic pain a gliopathy? Pain 2013;154 Suppl 1:S10–28.
    • (2013) Pain , vol.154 , pp. S10-28
    • Ji, R.R.1    Berta, T.2    Nedergaard, M.3
  • 46
    • 0036135610 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells
    • Cui YH, Le Y, Gong W, Proost P, van Damme J, Murphy WJ, et al. Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells. J Immunol 2002;168:434–42.
    • (2002) J Immunol , vol.168 , pp. 434-442
    • Cui, Y.H.1    Le, Y.2    Gong, W.3    Proost, P.4    van Damme, J.5    Murphy, W.J.6
  • 47
    • 77956238695 scopus 로고    scopus 로고
    • Norepinephrine promotes microglia to uptake and degrade amyloid β peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme
    • Kong Y, Ruan L, Qian L, Liu X, Le Y. Norepinephrine promotes microglia to uptake and degrade amyloid β peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme. J Neurosci 2010;30:11848–57.
    • (2010) J Neurosci , vol.30 , pp. 11848-11857
    • Kong, Y.1    Ruan, L.2    Qian, L.3    Liu, X.4    Le, Y.5
  • 48
    • 79956201836 scopus 로고    scopus 로고
    • Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord
    • Lee Y, Pai M, Brederson JD, Wilcox D, Hsieh G, Jarvis MF, et al. Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. Mol Pain 2011;7:39.
    • (2011) Mol Pain , vol.7 , pp. 39
    • Lee, Y.1    Pai, M.2    Brederson, J.D.3    Wilcox, D.4    Hsieh, G.5    Jarvis, M.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.