메뉴 건너뛰기




Volumn 73, Issue 3-4, 2005, Pages 189-196

Lipoxin A4 biology in the human synovium. Role of the ALX signaling pathways in modulation of inflammatory arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOXIN A; METALLOPROTEINASE; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA; CYTOKINE; LIPOXIN; LIPOXIN RECEPTOR;

EID: 24344444571     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2005.05.005     Document Type: Article
Times cited : (20)

References (54)
  • 1
    • 0036730319 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis: Pivotal cytokines involved in bone degradation and inflammation
    • C.O. Bingham The pathogenesis of rheumatoid arthritis: pivotal cytokines involved in bone degradation and inflammation J. Rheumatol. 65 S 2002 3
    • (2002) J. Rheumatol. , vol.65 , Issue.S , pp. 3
    • Bingham, C.O.1
  • 5
    • 0033981281 scopus 로고    scopus 로고
    • Exacerbation of acute inflammatory arthritis by the colony-stimulating factors CSF-I and granulocyte macrophage (GM)-CSF: Evidence of macrophage infiltration and local proliferation
    • R.J. Bischof, D. Zafiropoulos, J.A. Hamilton, and I.K. Campbell Exacerbation of acute inflammatory arthritis by the colony-stimulating factors CSF-I and granulocyte macrophage (GM)-CSF: evidence of macrophage infiltration and local proliferation Clin. Exp. Immunol. 119 2000 361
    • (2000) Clin. Exp. Immunol. , vol.119 , pp. 361
    • Bischof, R.J.1    Zafiropoulos, D.2    Hamilton, J.A.3    Campbell, I.K.4
  • 6
    • 0034467018 scopus 로고    scopus 로고
    • Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion
    • D.E. Woolley, and L.C. Tetlow Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion Arthritis Res. 2 2000 5
    • (2000) Arthritis Res. , vol.2 , pp. 5
    • Woolley, D.E.1    Tetlow, L.C.2
  • 8
    • 0023395177 scopus 로고
    • Autoimmunity in rheumatoid arthritis. An approach via a study of B lymphocytes
    • R.N. Maini, C. Plater-Zyberk, and E. Andrew Autoimmunity in rheumatoid arthritis. An approach via a study of B lymphocytes Rheum. Dis. Clin. North Am. 2 1987 319
    • (1987) Rheum. Dis. Clin. North Am. , vol.2 , pp. 319
    • Maini, R.N.1    Plater-Zyberk, C.2    Andrew, E.3
  • 9
    • 24344456967 scopus 로고    scopus 로고
    • Invasive fibroblast-like synoviocytes in rheumatoid arthritis
    • G.S. Firestein Invasive fibroblast-like synoviocytes in rheumatoid arthritis Rheum. Arthritis 39 1996 I781
    • (1996) Rheum. Arthritis , vol.39 , pp. 781
    • Firestein, G.S.1
  • 10
    • 0035018695 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis: The role of synoviocytes
    • Y. Yamanishi, and G.S. Firestein Pathogenesis of rheumatoid arthritis: the role of synoviocytes Rheum. Dis. Clin. North Am. 2 2001 355
    • (2001) Rheum. Dis. Clin. North Am. , vol.2 , pp. 355
    • Yamanishi, Y.1    Firestein, G.S.2
  • 11
    • 0034672092 scopus 로고    scopus 로고
    • Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: Dominant role for NF-kB but not C/EBP or c-Jun
    • C. Georganas, H. Liu, H. Perlman, A. Hoffmann, B. Thimmapaya, and R.M. Pope Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: dominant role for NF-kB but not C/EBP or c-Jun J. Immunol. 165 2000 7199
    • (2000) J. Immunol. , vol.165 , pp. 7199
    • Georganas, C.1    Liu, H.2    Perlman, H.3    Hoffmann, A.4    Thimmapaya, B.5    Pope, R.M.6
  • 12
    • 0035555275 scopus 로고    scopus 로고
    • Pathogenesis of arthritis: Recent research progress
    • M. Feldmann Pathogenesis of arthritis: recent research progress Nat. Immunol. 2 2001 771
    • (2001) Nat. Immunol. , vol.2 , pp. 771
    • Feldmann, M.1
  • 13
    • 0026744973 scopus 로고
    • Properties of pro-inflammatory cell type-specific leukocyte chemotacticcytokines, interleukin 8 (lL-8) and monocyte chemotactic and activating factor (MCAF)
    • N. Mukaida, A. Harada, K. Yasumoto, and K. Matsushima Properties of pro-inflammatory cell type-specific leukocyte chemotacticcytokines, interleukin 8 (lL-8) and monocyte chemotactic and activating factor (MCAF) Microbiol. Immunol. 36 1992 773
    • (1992) Microbiol. Immunol. , vol.36 , pp. 773
    • Mukaida, N.1    Harada, A.2    Yasumoto, K.3    Matsushima, K.4
  • 14
    • 0029827299 scopus 로고    scopus 로고
    • Differential expression of GRO alpha and IL-8 mRNA in psoriasis: A model for neutrophil migration and accumulation in vi Yo
    • R. GiIlitzer, U. Ritter, U. Spandau, M. Goebeler, and E.B. Brocker Differential expression of GRO alpha and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vi Yo J. Invest. Dermatol. 107 1996 778
    • (1996) J. Invest. Dermatol. , vol.107 , pp. 778
    • Giilitzer, R.1    Ritter, U.2    Spandau, U.3    Goebeler, M.4    Brocker, E.B.5
  • 16
    • 0036188479 scopus 로고    scopus 로고
    • Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis
    • Z. Han, L. Chang, Y. Yamanishi, M. Karin, and G.S. Firestein Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis Arthritis Rheum. 46 2002 81 88
    • (2002) Arthritis Rheum. , vol.46 , pp. 81-88
    • Han, Z.1    Chang, L.2    Yamanishi, Y.3    Karin, M.4    Firestein, G.S.5
  • 17
    • 0034931503 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
    • Z. Han, D.L. Boyle, L. Chang, B. Bennett, M. Karin, L. Yang, A.M. Manning, and G.S. Firestein c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis J. Clin. Invest. 108 2001 73
    • (2001) J. Clin. Invest. , vol.108 , pp. 73
    • Han, Z.1    Boyle, D.L.2    Chang, L.3    Bennett, B.4    Karin, M.5    Yang, L.6    Manning, A.M.7    Firestein, G.S.8
  • 18
    • 0033996762 scopus 로고    scopus 로고
    • The IB kinase (IKK) and NF-kB: Key elements of proinflaminatory signalling
    • M. Karin, and M. Delhase The IB kinase (IKK) and NF-kB: key elements of proinflaminatory signalling Semin. Immunol. 12 2000 85
    • (2000) Semin. Immunol. , vol.12 , pp. 85
    • Karin, M.1    Delhase, M.2
  • 19
    • 0032428729 scopus 로고    scopus 로고
    • AP-I and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis
    • Z. Han, D.L. Boyle, A.M. Manning, and G.S. Firestein AP-I and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis Autoimmunity 28 1998 197
    • (1998) Autoimmunity , vol.28 , pp. 197
    • Han, Z.1    Boyle, D.L.2    Manning, A.M.3    Firestein, G.S.4
  • 21
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • J.W. Pierce, R. Schoenleber, G. Jesmok, J. Best, S.A. Moore, T. Collins, and M.E. Gerritsen Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo J. Biol. Chem. 272 1997 21096
    • (1997) J. Biol. Chem. , vol.272 , pp. 21096
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerritsen, M.E.7
  • 22
    • 0031418574 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory cytokines in rheumatoid arthritis
    • P. Isomaki, and J. Punnonen Pro- and anti-inflammatory cytokines in rheumatoid arthritis Ann. Med. 29 1997 499
    • (1997) Ann. Med. , vol.29 , pp. 499
    • Isomaki, P.1    Punnonen, J.2
  • 23
    • 0033387072 scopus 로고    scopus 로고
    • Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signalling pathways in human OA synovial fibroblast
    • N. Alaaeddine, J.A. Di Battista, J.P. Pelletier, K. Kiansa, J.M. Cloutier, and J. Martel-Pelletier Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signalling pathways in human OA synovial fibroblast Cytokine 11 1999 1020
    • (1999) Cytokine , vol.11 , pp. 1020
    • Alaaeddine, N.1    Di Battista, J.A.2    Pelletier, J.P.3    Kiansa, K.4    Cloutier, J.M.5    Martel-Pelletier, J.6
  • 24
    • 0037949395 scopus 로고    scopus 로고
    • Lipid-derived mediators in endogenous anti-inflammation and resolution: Lipoxins and aspirin-triggered 15-epi-Lipoxins
    • C.N. Serhan, and N. Chiang Lipid-derived mediators in endogenous anti-inflammation and resolution: Lipoxins and aspirin-triggered 15-epi-Lipoxins Scientific World J. 2 2002 169
    • (2002) Scientific World J. , vol.2 , pp. 169
    • Serhan, C.N.1    Chiang, N.2
  • 25
    • 0036669399 scopus 로고    scopus 로고
    • Lipoxins and aspirin triggered 15-epi-lipoxin biosynthesis: An update and role in antiinflammation and pro-resolution
    • C.N. Serhan Lipoxins and aspirin triggered 15-epi-lipoxin biosynthesis: an update and role in antiinflammation and pro-resolution Prostaglandins Other Lipid Mediat. 68 2002 433
    • (2002) Prostaglandins Other Lipid Mediat. , vol.68 , pp. 433
    • Serhan, C.N.1
  • 26
    • 0030924291 scopus 로고    scopus 로고
    • Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: Evidence for anti-inflammatory receptors
    • T. Takano, S. Fiore, J.F. Maddox, H.R. Brady, N.A. Petasisand, and C.N. Serhan Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors J. Exp. Med. 185 1997 1693
    • (1997) J. Exp. Med. , vol.185 , pp. 1693
    • Takano, T.1    Fiore, S.2    Maddox, J.F.3    Brady, H.R.4    Petasisand, N.A.5    Serhan, C.N.6
  • 28
    • 0034144689 scopus 로고    scopus 로고
    • Lipoxin A4 inhibits IL-I beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases
    • S. Sodin-Semrl, B. Taddeo, D. Tseng, J. Varga, and S. Fiore Lipoxin A4 inhibits IL-I beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases J. Immunol. 164 2000 2660
    • (2000) J. Immunol. , vol.164 , pp. 2660
    • Sodin-Semrl, S.1    Taddeo, B.2    Tseng, D.3    Varga, J.4    Fiore, S.5
  • 29
    • 9644290796 scopus 로고    scopus 로고
    • Activation of LXA4R or serumamyloid a results in opposite regulation of NF-kB DNA binding in human synovial fibroblasts
    • S. Fiore, S. Sodin-Semrl, Y. Kang, and J. Varga Activation of LXA4R or serumamyloid A results in opposite regulation of NF-kB DNA binding in human synovial fibroblasts Arthritis Rheum. 43 2000 S158
    • (2000) Arthritis Rheum. , vol.43 , pp. 158
    • Fiore, S.1    Sodin-Semrl, S.2    Kang, Y.3    Varga, J.4
  • 30
    • 0037387732 scopus 로고    scopus 로고
    • Human ALX receptor regulates neutrophil recruitment in transgenic mice: Roles in inflammation and host defense
    • P.R. Devchand, M. Arita, S. Hong, G. Bannenberg, R.L. Mousignac, K. Gronert, and C.N. Serhan Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense FASEB J. 17 2003 652
    • (2003) FASEB J. , vol.17 , pp. 652
    • Devchand, P.R.1    Arita, M.2    Hong, S.3    Bannenberg, G.4    Mousignac, R.L.5    Gronert, K.6    Serhan, C.N.7
  • 32
    • 0034673318 scopus 로고    scopus 로고
    • A novel function of serum amyloid A: A potent stimulus for the release of tumor necrosis factor-alpha, interleukin-I beta, and interleukin-8 by human blood neutrophil
    • C.J. Furlaneto, and A. Campa A novel function of serum amyloid A: a potent stimulus for the release of tumor necrosis factor-alpha, interleukin-I beta, and interleukin-8 by human blood neutrophil Biochem. Biophys. Res. Commun. 268 2000 405
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 405
    • Furlaneto, C.J.1    Campa, A.2
  • 33
    • 0037441872 scopus 로고    scopus 로고
    • Serum amyloid a induces IL-8 secretion through a G protein-coupled receptor, FPRLI/LXA4R
    • R. He, H. Sang, and R.D. Ye Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRLI/LXA4R Blood 101 2003 1572
    • (2003) Blood , vol.101 , pp. 1572
    • He, R.1    Sang, H.2    Ye, R.D.3
  • 36
    • 0033569982 scopus 로고    scopus 로고
    • Serum amyloid A, the major vertebrate acute-phase reactant
    • C.M. Uhlar, and A.S. Whitehead Serum amyloid A, the major vertebrate acute-phase reactant Eur. J. Biochem. 265 1999 501
    • (1999) Eur. J. Biochem. , vol.265 , pp. 501
    • Uhlar, C.M.1    Whitehead, A.S.2
  • 37
    • 0026081942 scopus 로고
    • Tumor necrosis factor (TNF) inhibits interleukin (lL)-1 and/or IL-6 stimulated synthesis of C reactive protein (CRP) and serum amyloid a (SAA) in primary cultures of human hepatocytes
    • S.H. Yap, H.J. Moshage, B.P. Hazenberg, H.M. Roelofs, J. Bijzet, P.C. Limburg, L.A. Aarden, and M.H. van Rijswijk Tumor necrosis factor (TNF) inhibits interleukin (lL)-1 and/or IL-6 stimulated synthesis of C reactive protein (CRP) and serum amyloid A (SAA) in primary cultures of human hepatocytes Biochim. Biophys. Acta 1091 1991 405
    • (1991) Biochim. Biophys. Acta , vol.1091 , pp. 405
    • Yap, S.H.1    Moshage, H.J.2    Hazenberg, B.P.3    Roelofs, H.M.4    Bijzet, J.5    Limburg, P.C.6    Aarden, L.A.7    Van Rijswijk, M.H.8
  • 39
    • 9644303534 scopus 로고    scopus 로고
    • Opposing regulation of interleukin-8 and NF-kB responses by lipoxin A4 and seruma amyloid a via the common lipoxin A4 receptor
    • S. Sodin-Semrl, A. Spagnolo, R. Mikus, R. Barbaro, J. Varga, and S. Fiore Opposing regulation of interleukin-8 and NF-kB responses by lipoxin A4 and seruma amyloid A via the common lipoxin A4 receptor Int. J. Immunopathol. Pharmacol. 17 2004 145 155
    • (2004) Int. J. Immunopathol. Pharmacol. , vol.17 , pp. 145-155
    • Sodin-Semrl, S.1    Spagnolo, A.2    Mikus, R.3    Barbaro, R.4    Varga, J.5    Fiore, S.6
  • 40
    • 0029417201 scopus 로고
    • Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: Inhibition of CD 11b/18 expression by lipoxin A4-lipoxin A4 receptor interaction
    • S. Fiore, and C.N. Serhan Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD 11b/18 expression by lipoxin A4-lipoxin A4 receptor interaction Biochemistry 34 1995 16678
    • (1995) Biochemistry , vol.34 , pp. 16678
    • Fiore, S.1    Serhan, C.N.2
  • 42
    • 0028359379 scopus 로고
    • Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor
    • S. Fiore, J.F. Maddox, H.D. Perezand, and C.N. Serhan Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor J. Exp. Med. 180 1994 253
    • (1994) J. Exp. Med. , vol.180 , pp. 253
    • Fiore, S.1    Maddox, J.F.2    Perezand, H.D.3    Serhan, C.N.4
  • 43
    • 0026714965 scopus 로고
    • Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils
    • S. Fiore, S.W. Ryeom, P.F. Weller, and C.N. Serhan Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils J. Biol. Chem. 267 1992 16168
    • (1992) J. Biol. Chem. , vol.267 , pp. 16168
    • Fiore, S.1    Ryeom, S.W.2    Weller, P.F.3    Serhan, C.N.4
  • 44
    • 0035348171 scopus 로고    scopus 로고
    • Mechanisms in anti-inflammation and resolution: The role of lipoxins and aspirin-triggered lipoxins
    • I.M. Fierro, and C.N. Serhan Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins Braz. J. Med. Biol. Res. 34 2001 555
    • (2001) Braz. J. Med. Biol. Res. , vol.34 , pp. 555
    • Fierro, I.M.1    Serhan, C.N.2
  • 46
    • 0036156691 scopus 로고    scopus 로고
    • Novel lipid mediator regulators of endothelial cell proliferation andmigration: Aspirin-triggered-15R-Lipoxin A4 and Lipoxin A4′
    • I.M. Fierro, J.L. Kutok, and C.N. Serhan Novel lipid mediator regulators of endothelial cell proliferation andmigration: aspirin-triggered-15R-Lipoxin A4 and Lipoxin A4′ J. Pharmacol. Exp. Therap. 300 2002 385
    • (2002) J. Pharmacol. Exp. Therap. , vol.300 , pp. 385
    • Fierro, I.M.1    Kutok, J.L.2    Serhan, C.N.3
  • 47
    • 0036831229 scopus 로고    scopus 로고
    • Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation
    • B. McMahon, D. Mitchell, R. Shattock, F. Martin, H.R. Brady, and C. Godson Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation FASEB J. 16 2002 1817
    • (2002) FASEB J. , vol.16 , pp. 1817
    • McMahon, B.1    Mitchell, D.2    Shattock, R.3    Martin, F.4    Brady, H.R.5    Godson, C.6
  • 48
    • 0000485181 scopus 로고    scopus 로고
    • A seven transmembrane, G protein-coupled receptor, FPRLI, mediates the chemotactic activity of serum amyloid a for human phagocytic cells
    • S.B. Su, W. Gong, J.L. Gao, W. Shen, P.M. Murphy, J.J. Oppenheim, and J.M. Wang A seven transmembrane, G protein-coupled receptor, FPRLI, mediates the chemotactic activity of serum amyloid A for human phagocytic cells J. Exp. Med. 189 1999 395
    • (1999) J. Exp. Med. , vol.189 , pp. 395
    • Su, S.B.1    Gong, W.2    Gao, J.L.3    Shen, W.4    Murphy, P.M.5    Oppenheim, J.J.6    Wang, J.M.7
  • 49
    • 0034599741 scopus 로고    scopus 로고
    • Activation of lipoxin A(4) receptors by aspirin triggered lipoxins and select peptides evokes ligand specific responses in inflammation
    • N. Chiang, I.M. Fierro, K. Gronert, and C.N. Serhan Activation of lipoxin A(4) receptors by aspirin triggered lipoxins and select peptides evokes ligand specific responses in inflammation J. Exp. Med. 191 2000 1197
    • (2000) J. Exp. Med. , vol.191 , pp. 1197
    • Chiang, N.1    Fierro, I.M.2    Gronert, K.3    Serhan, C.N.4
  • 51
    • 0036852720 scopus 로고    scopus 로고
    • Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A(4) receptor
    • M. Perretti, N. Chiang, M. La, I.M. Fierro, S. Marullo, S.J. Getting, E. Solito, and C.N. Serhan Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A(4) receptor Nat. Med. 8 2002 1296
    • (2002) Nat. Med. , vol.8 , pp. 1296
    • Perretti, M.1    Chiang, N.2    La, M.3    Fierro, I.M.4    Marullo, S.5    Getting, S.J.6    Solito, E.7    Serhan, C.N.8
  • 52
    • 0031805385 scopus 로고    scopus 로고
    • Serum amyloid a protein induces production of matrix metalloproteinases by human synovial fibroblasts
    • K. Migita, Y. Kawabe, M. Tominaga, T. Origuchi, T. Aoyagi, and K. Eguchi Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts Lab. Invest 78 1998 535
    • (1998) Lab. Invest , vol.78 , pp. 535
    • Migita, K.1    Kawabe, Y.2    Tominaga, M.3    Origuchi, T.4    Aoyagi, T.5    Eguchi, K.6
  • 53
    • 0027417158 scopus 로고
    • The acute phase reactant serum amyloid a (SAA3) is a novel substrate for degradation by the metalloproteinases collagenase and stromelysin
    • T.I. Mitchell, J.J. Jeffrey, R.D. Palmiter, and C.E. Brinckerhoff The acute phase reactant serum amyloid A (SAA3) is a novel substrate for degradation by the metalloproteinases collagenase and stromelysin Biochim. Biophys. Acta 1156 1993 245
    • (1993) Biochim. Biophys. Acta , vol.1156 , pp. 245
    • Mitchell, T.I.1    Jeffrey, J.J.2    Palmiter, R.D.3    Brinckerhoff, C.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.