Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells

Journal of Immunology

Volumn 168, Issue 1, 2002, Pages 434-442

  Cui, Y H ^a   Le, Y ^a   Gong, W ^a   Proost, P ^a   Van Damme, J ^a   Murphy, W J ^a   Ji Ming Wang, ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHEMOATTRACTANT; CHEMOATTRACTANT RECEPTOR; CHEMOTACTIC PEPTIDE; CHEMOTACTIC PEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 1; FORMYLPEPTIDE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; CONTROLLED STUDY; GENE EXPRESSION; HOST RESISTANCE; INFLAMMATION; MICROBIAL IMMUNITY; MICROGLIA; MONONUCLEAR PHAGOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

EID: 0036135610     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.1.434     Document Type: Article

References (42)

1. Chemoattractant stimulus-response coupling
2. Complement: Biologically active products
3. Chemokines
4. A burgeoning family of biological mediators: Chemokines and chemokine receptors
5. The N-formyl peptide chemotactic receptors
6. The N-formyl peptide receptor: A model for the study of chemoattractant receptor structure and function
7. Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors
8. Serum amyloid A is a chemotactic agonist at FPR2, a low-affinity N-formylpeptide receptor on mouse neutrophils
9. The HIV-1 cell entry inhibitor T-20 potently chemoattracts neutrophils by specifically activating the N-formylpeptide receptor
10. Impaired antibacterial host defense in mice lacking the N-formylpeptide
11. A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells
12. Amyloid β42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1
13. Cutting edge: The neurotoxic prion peptide fragment PrP 106-126 is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1
14. Reaction microgliosis
15. Microglia: A sensor for pathological events in the CNS
16. Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
17. Functional expression of CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes
18. Cultured rat microglia express functional β-chemokine receptors
19. Chemotaxis by a CNS macrophage, the microglia
20. Utilization of two seven-transmembrane G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation
21. Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines
22. Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin
23. Expression of the receptor for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia
24. Enhanced expression of chemotactic receptors in multiple sclerosis lesions
25. Chemotactic-like receptors and Aβ peptide induced responses in Alzheimer's disease
26. Recognition of Gram-negative bacteria and endotoxin by the innate immune system
27. Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes
28. Lipopolysaccharide inhibits HIV-1 infection of monocyte-derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5
29. LPS down-regulates the expression of chemokine receptor CCR2 in mice and abolishes macrophage infiltration in acute inflammation
30. Cutting edge: Differential regulation of chemokine receptors during dendritic cell maturation: A model for their trafficking properties
31. Selective inhibition of the chemokine receptor CCR2 in human monocytes by 1FN-γ
32. Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-α-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression
33. Granulocyte-colony stimulating factor and lipopolysaccharide regulate the expression of interleukin 8 receptors on polymorphonuclear leukocytes
34. CXCR1 and CXCR2 are rapidly down-modulated by bacterial endotoxin through a unique agonist-independent, tyrosine kinase-dependent mechanism
35. Regulation of CCR2 chemokine receptor mRNA stability
36. Priming induces functional coupling of N-formyl-methionyl-leucyl-phenylalanine receptors in equine neutrophils
37. Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils
38. Escherichia coli-induced activation of neutrophil NADH-oxidase: Lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites
39. Lipopolysaccharide modulates receptors for leukotriene B4, C5a, and formyl-methionyl-leucyl-phenylalanine on rabbit polymorphonuclear leukocytes
40. Modulation of monocyte chemotactic function in inflammatory lesions: Role of inflammatory mediators
41. Interleukin 10 increases CCR5 expression and HIV infection in human monocytes
42. The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations