Alteration of neuronal excitability and short-term synaptic plasticity in the prefrontal cortex of a mouse model of mental illness

Journal of Neuroscience

Volumn 37, Issue 15, 2017, Pages 4158-4180

  Crabtree, Gregg W ^a   Sun, Ziyi ^a   Kvajo, Mirna ^a   Broek, Jantine A C ^c   Fénelon, Karine ^a   McKellar, Heather ^b   Xiao, Lan ^d   Xu, Bin ^e   Bahn, Sabine ^c   O’Donnell, James M ^f   Gogos, Joseph A ^a,e  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e NewYork Presbyterian Hospital   (United States)

^f UNIVERSITY AT BUFFALO   (United States)

Author keywords

Disc1 mouse model; Excitability; Kv channels; Prefrontal cortex; Schizophrenia; Synaptic plasticity

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; PHOSPHODIESTERASE IV; POTASSIUM CHANNEL KV1.1; VOLTAGE GATED CALCIUM CHANNEL; DISC1 PROTEIN, MOUSE; NERVE PROTEIN;

ACTION POTENTIAL; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LAYER; CONTROLLED STUDY; CYTOARCHITECTURE; ELECTROPHYSIOLOGICAL PROCEDURES; EMBRYO; ENZYME ACTIVITY; FEMALE; GENE MUTATION; GENOTYPE; GLUTAMATERGIC SYNAPSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MENTAL DISEASE; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVE PROJECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; POTASSIUM CURRENT; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEOMICS; PYRAMIDAL NERVE CELL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHIZOPHRENIA; SYNAPSE; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; GENETICS; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; PREFRONTAL CORTEX; PREGNANCY; SCHIZOPHRENIA;

EID: 85018581596     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4345-15.2017     Document Type: Article

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