ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

Oncogene

Volumn 36, Issue 40, 2017, Pages 5593-5608

  Chen, D ^a   Fan, Z ^a,b,c   Rauh, M ^a   Buchfelder, M ^a   Eyupoglu, I Y ^a   Savaskan, N ^a,d  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c Laboratory of Exercise and Health   (Switzerland)

^d BiMECON Ent   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANTINEOPLASTIC AGENT; ERASTIN; GLUTAMIC ACID; RSL 3; SMALL INTERFERING RNA; SORAFENIB; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; ATF4 PROTEIN, HUMAN; IRON; SLC7A11 PROTEIN, HUMAN;

ANCHORAGE INDEPENDENT GROWTH; ANGIOGENESIS; ARTICLE; ASTROCYTOMA; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; FERROPTOSIS; GENE; GENE EXPRESSION; GENE SILENCING; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE CELL NECROSIS; OLIGODENDROGLIOMA; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT; XCT GENE; BRAIN TUMOR; CELL DEATH; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); NERVE CELL; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE; VASCULARIZATION;

ACTIVATING TRANSCRIPTION FACTOR 4; AMINO ACID TRANSPORT SYSTEM Y+; BRAIN NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; GLUTAMIC ACID; HUMANS; IRON; NEOVASCULARIZATION, PATHOLOGIC; NEURONS;

EID: 85018380560     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2017.146     Document Type: Article

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