메뉴 건너뛰기




Volumn 11, Issue 3, 2016, Pages

Immunological characterization of plant-based HIV-1 Gag/Dgp41 virus-like particles

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GLYCOPROTEIN GP 41; GP41 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; VIRUS LIKE PARTICLE VACCINE;

EID: 85018305114     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151842     Document Type: Article
Times cited : (13)

References (75)
  • 1
    • 40849136223 scopus 로고    scopus 로고
    • The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design
    • PMID: 18322034.
    • Montero M, van Houten NE, Wang X, Scott JK. The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design. Microbiol Mol Biol Rev. 2008; 72(1):54–84. PMID: 18322034. doi: 10.1128/MMBR.00020-07
    • (2008) Microbiol Mol Biol Rev , vol.72 , Issue.1 , pp. 54-84
    • Montero, M.1    van Houten, N.E.2    Wang, X.3    Scott, J.K.4
  • 2
    • 84928946145 scopus 로고    scopus 로고
    • Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41
    • PMID: 25155369; PubMed Central PMCID: PMC4241111
    • Gong Z, Kessans SA, Song L, Dorner K, Lee HH, Meador LR, et al. Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41. Protein Sci. 2014; 23(11):1607–18. doi: 10.1002/pro.2540 PMID: 25155369; PubMed Central PMCID: PMC4241111.
    • (2014) Protein Sci , vol.23 , Issue.11 , pp. 1607-1618
    • Gong, Z.1    Kessans, S.A.2    Song, L.3    Dorner, K.4    Lee, H.H.5    Meador, L.R.6
  • 3
    • 0035873475 scopus 로고    scopus 로고
    • Secretory IgA Specific for a Conserved Epitope on gp41 Envelope Glycoprotein Inhibits Epithelial Transcytosis of HIV-1
    • PMID: 11342649
    • Alfsen A, Iniguez P, Bouguyon E, Bomsel M. Secretory IgA Specific for a Conserved Epitope on gp41 Envelope Glycoprotein Inhibits Epithelial Transcytosis of HIV-1. J Immunol. 2001; 166(10):6257–65. PMID: 11342649.
    • (2001) J Immunol , vol.166 , Issue.10 , pp. 6257-6265
    • Alfsen, A.1    Iniguez, P.2    Bouguyon, E.3    Bomsel, M.4
  • 4
    • 84859044775 scopus 로고    scopus 로고
    • Transmembrane Domain Membrane Proximal External Region but Not Surface Unit-Directed Broadly Neutralizing HIV-1 Antibodies Can Restrict Dendritic Cell-Mediated HIV-1 Trans-infection
    • Epub 2012/03/08. jis183 pii: PMID: 22396600; PubMed Central PMCID: PMC3308909
    • Sagar M, Akiyama H, Etemad B, Ramirez N, Freitas I, Gummuluru S. Transmembrane Domain Membrane Proximal External Region but Not Surface Unit-Directed Broadly Neutralizing HIV-1 Antibodies Can Restrict Dendritic Cell-Mediated HIV-1 Trans-infection. J Infect Dis. 2012; 205(8):1248–57. Epub 2012/03/08. jis183 [pii] doi: 10.1093/infdis/jis183 PMID: 22396600; PubMed Central PMCID: PMC3308909.
    • (2012) J Infect Dis , vol.205 , Issue.8 , pp. 1248-1257
    • Sagar, M.1    Akiyama, H.2    Etemad, B.3    Ramirez, N.4    Freitas, I.5    Gummuluru, S.6
  • 5
    • 34247341369 scopus 로고    scopus 로고
    • Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells
    • PMID: 17234232
    • Magerus-Chatinet A, Yu H, Garcia S, Ducloux E, Terris B, Bomsel M. Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells. Virology. 2007; 362(1):67–74. PMID: 17234232.
    • (2007) Virology , vol.362 , Issue.1 , pp. 67-74
    • Magerus-Chatinet, A.1    Yu, H.2    Garcia, S.3    Ducloux, E.4    Terris, B.5    Bomsel, M.6
  • 6
    • 33646872613 scopus 로고    scopus 로고
    • Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649–684), a mucosal subunit HIV/AIDS vaccine candidate
    • PMID: 16621185
    • Matoba N, Geyer BC, Kilbourne J, Alfsen A, Bomsel M, Mor TS. Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649–684), a mucosal subunit HIV/AIDS vaccine candidate. Vaccine. 2006; 24:5047–55. PMID: 16621185.
    • (2006) Vaccine , vol.24 , pp. 5047-5055
    • Matoba, N.1    Geyer, B.C.2    Kilbourne, J.3    Alfsen, A.4    Bomsel, M.5    Mor, T.S.6
  • 7
    • 4544359230 scopus 로고    scopus 로고
    • A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs
    • PMID: 15347807
    • Matoba N, Magerus A, Geyer BC, Zhang Y, Muralidharan M, Alfsen A, et al. A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs. Proc Natl Acad Sci U S A. 2004; 101 (37):13584–9. PMID: 15347807.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.37 , pp. 13584-13589
    • Matoba, N.1    Magerus, A.2    Geyer, B.C.3    Zhang, Y.4    Muralidharan, M.5    Alfsen, A.6
  • 8
    • 0035500882 scopus 로고    scopus 로고
    • Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers
    • PMID: 11595287
    • Broliden K, Hinkula J, Devito C, Kiama P, Kimani J, Trabbatoni D, et al. Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers. Immunol Lett. 2001; 79(1–2):29–36. PMID: 11595287.
    • (2001) Immunol Lett , vol.79 , Issue.1-2 , pp. 29-36
    • Broliden, K.1    Hinkula, J.2    Devito, C.3    Kiama, P.4    Kimani, J.5    Trabbatoni, D.6
  • 9
    • 0034327707 scopus 로고    scopus 로고
    • Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells
    • PMID: 11046049
    • Devito C, Broliden K, Kaul R, Svensson L, Johansen K, Kiama P, et al. Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells. J Immunol. 2000; 165(9):5170–6. PMID: 11046049.
    • (2000) J Immunol , vol.165 , Issue.9 , pp. 5170-5176
    • Devito, C.1    Broliden, K.2    Kaul, R.3    Svensson, L.4    Johansen, K.5    Kiama, P.6
  • 10
    • 0035895644 scopus 로고    scopus 로고
    • Mucosal IgA in exposed, uninfected subjects: Evidence for a role in protection against HIV infection
    • PMID: 11273233
    • Kaul R, Plummer F, Clerici M, Bomsel M, Lopalco L, Broliden K. Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection. Aids. 2001; 15(3):431–2. PMID: 11273233.
    • (2001) Aids , vol.15 , Issue.3 , pp. 431-432
    • Kaul, R.1    Plummer, F.2    Clerici, M.3    Bomsel, M.4    Lopalco, L.5    Broliden, K.6
  • 11
    • 84884414183 scopus 로고    scopus 로고
    • Secretory IgA specific for MPER can protect from HIV-1 infection in vitro
    • Epub 2013/05/ 23.: PMID: 23696073
    • Benjelloun F, Dawood R, Urcuqui-Inchima S, Rochereau N, Chanut B, Verrier B, et al. Secretory IgA specific for MPER can protect from HIV-1 infection in vitro. AIDS. 2013; 27(12):1992–5. Epub 2013/05/ 23. doi: 10.1097/QAD.0b013e3283632ea1 PMID: 23696073.
    • (2013) AIDS , vol.27 , Issue.12 , pp. 1992-1995
    • Benjelloun, F.1    Dawood, R.2    Urcuqui-Inchima, S.3    Rochereau, N.4    Chanut, B.5    Verrier, B.6
  • 12
    • 11144227042 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
    • PMID: 15613352; PubMed Central PMCID: PMC538539
    • Zwick MB, Jensen R, Church S, Wang M, Stiegler G, Kunert R, et al. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J Virol. 2005; 79(2):1252–61. doi: 10.1128/JVI.79.2.1252-1261.2005 PMID: 15613352; PubMed Central PMCID: PMC538539.
    • (2005) J Virol , vol.79 , Issue.2 , pp. 1252-1261
    • Zwick, M.B.1    Jensen, R.2    Church, S.3    Wang, M.4    Stiegler, G.5    Kunert, R.6
  • 13
    • 73949154006 scopus 로고    scopus 로고
    • Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
    • Epub 2009/11/13.: PMID: 19906907; PubMed Central PMCID: PMC2812338
    • Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. Journal of virology. 2010; 84(3):1302–13. Epub 2009/11/13. doi: 10.1128/JVI. 01272-09 PMID: 19906907; PubMed Central PMCID: PMC2812338.
    • (2010) Journal of Virology , vol.84 , Issue.3 , pp. 1302-1313
    • Hessell, A.J.1    Rakasz, E.G.2    Tehrani, D.M.3    Huber, M.4    Weisgrau, K.L.5    Landucci, G.6
  • 14
    • 84866495323 scopus 로고    scopus 로고
    • Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
    • Epub 2012/09/25.: PMID: 22999947
    • Kwong PD, Mascola JR. Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies. Immunity. 2012; 37(3):412–25. Epub 2012/09/25. doi: 10.1016/j.immuni.2012.08.012 PMID: 22999947.
    • (2012) Immunity , vol.37 , Issue.3 , pp. 412-425
    • Kwong, P.D.1    Mascola, J.R.2
  • 15
    • 84866493348 scopus 로고    scopus 로고
    • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
    • Epub 2012/11/16.: PMID: 23151583
    • Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012; 491(7424):406–12. Epub 2012/11/16. doi: 10.1038/nature11544 PMID: 23151583.
    • (2012) Nature , vol.491 , Issue.7424 , pp. 406-412
    • Huang, J.1    Ofek, G.2    Laub, L.3    Louder, M.K.4    Doria-Rose, N.A.5    Longo, N.S.6
  • 16
    • 84911459185 scopus 로고    scopus 로고
    • Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: A comprehensive study using the most potent and broadly neutralizing monoclonal antibodies
    • PMID: 25231299; PubMed Central PMCID: PMC4248973
    • Bouvin-Pley M, Morgand M, Meyer L, Goujard C, Moreau A, Mouquet H, et al. Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies. J Virol. 2014; 88(23):13910–7. doi: 10.1128/JVI.02083-14 PMID: 25231299; PubMed Central PMCID: PMC4248973.
    • (2014) J Virol , vol.88 , Issue.23 , pp. 13910-13917
    • Bouvin-Pley, M.1    Morgand, M.2    Meyer, L.3    Goujard, C.4    Moreau, A.5    Mouquet, H.6
  • 17
    • 82355171239 scopus 로고    scopus 로고
    • Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41
    • PMID: 22140469; PubMed Central PMCID: PMC3227606
    • Dennison SM, Sutherland LL, Jaeger FH, Anasti KM, Parks R, Stewart S, et al. Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41. PLoS One. 2011; 6(11):e27824. doi: 10.1371/journal.pone.0027824 PMID: 22140469; PubMed Central PMCID: PMC3227606.
    • (2011) PLoS One , vol.6 , Issue.11
    • Dennison, S.M.1    Sutherland, L.L.2    Jaeger, F.H.3    Anasti, K.M.4    Parks, R.5    Stewart, S.6
  • 18
    • 84862309329 scopus 로고    scopus 로고
    • Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41
    • Epub 2012/06/05.: PMID: 22658900
    • Pastori C, Tudor D, Diomede L, Drillet AS, Jegerlehner A, Rohn TA, et al. Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41. Virology. 2012; 431(1–2):1–11. Epub 2012/06/05. doi: 10.1016/j.virol.2012.05.005 PMID: 22658900.
    • (2012) Virology , vol.431 , Issue.1-2 , pp. 1-11
    • Pastori, C.1    Tudor, D.2    Diomede, L.3    Drillet, A.S.4    Jegerlehner, A.5    Rohn, T.A.6
  • 19
    • 84874274760 scopus 로고    scopus 로고
    • Randomized phase I: Safety, immunogenicity and mucosal antiviral activity in young healthy women vaccinated with HIV-1 gp41 P1 peptide on virosomes
    • Epub 2013/02/26.: PMID: 23437055; PubMed Central PMCID: PMC3577797
    • Leroux-Roels G, Maes C, Clement F, van Engelenburg F, van den Dobbelsteen M, Adler M, et al. Randomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes. PloS one. 2013; 8(2):e55438. Epub 2013/02/26. doi: 10.1371/journal.pone.0055438 PMID: 23437055; PubMed Central PMCID: PMC3577797.
    • (2013) PloS One , vol.8 , Issue.2
    • Leroux-Roels, G.1    Maes, C.2    Clement, F.3    van Engelenburg, F.4    van den Dobbelsteen, M.5    Adler, M.6
  • 20
    • 84867630116 scopus 로고    scopus 로고
    • A blueprint for HIV vaccine discovery
    • Epub 2012/10/23.: PMID: 23084910; PubMed Central PMCID: PMC3513329
    • Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, et al. A Blueprint for HIV Vaccine Discovery. Cell host & microbe. 2012; 12(4):396–407. Epub 2012/10/23. doi: 10.1016/j.chom.2012.09. 008 PMID: 23084910; PubMed Central PMCID: PMC3513329.
    • (2012) Cell Host & Microbe , vol.12 , Issue.4 , pp. 396-407
    • Burton, D.R.1    Ahmed, R.2    Barouch, D.H.3    Butera, S.T.4    Crotty, S.5    Godzik, A.6
  • 21
    • 84878356025 scopus 로고    scopus 로고
    • Accelerating next-generation vaccine development for global disease prevention
    • PMID: 23723240; PubMed Central PMCID: PMC4026248
    • Koff WC, Burton DR, Johnson PR, Walker BD, King CR, Nabel GJ, et al. Accelerating next-generation vaccine development for global disease prevention. Science. 2013; 340(6136):1232910. doi: 10.1126/ science.1232910 PMID: 23723240; PubMed Central PMCID: PMC4026248.
    • (2013) Science , vol.340 , Issue.6136 , pp. 1232910
    • Koff, W.C.1    Burton, D.R.2    Johnson, P.R.3    Walker, B.D.4    King, C.R.5    Nabel, G.J.6
  • 22
    • 84901653387 scopus 로고    scopus 로고
    • HIV-1 envelope gp41 broadly neutralizing antibodies: Hurdles for vaccine development
    • PMID: 24853821; PubMed Central PMCID: PMC4031215
    • Verkoczy L, Kelsoe G, Haynes BF. HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development. PLoS Pathog. 2014; 10(5):e1004073. doi: 10.1371/journal.ppat.1004073 PMID: 24853821; PubMed Central PMCID: PMC4031215.
    • (2014) PLoS Pathog , vol.10 , Issue.5
    • Verkoczy, L.1    Kelsoe, G.2    Haynes, B.F.3
  • 23
    • 84864075527 scopus 로고    scopus 로고
    • Mechanism of membrane perturbation by the HIV-1 gp41 membrane-proximal external region and its modulation by cholesterol
    • Epub 2012/06/14.: PMID: 22692008
    • Ivankin A, Apellaniz B, Gidalevitz D, Nieva JL. Mechanism of membrane perturbation by the HIV-1 gp41 membrane-proximal external region and its modulation by cholesterol. Biochimica et biophysica acta. 2012; 1818(11):2521–8. Epub 2012/06/14. doi: 10.1016/j.bbamem.2012.06.002 PMID: 22692008.
    • (2012) Biochimica Et Biophysica Acta , vol.1818 , Issue.11 , pp. 2521-2528
    • Ivankin, A.1    Apellaniz, B.2    Gidalevitz, D.3    Nieva, J.L.4
  • 24
    • 84863229918 scopus 로고    scopus 로고
    • Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane
    • Epub 2012/01/13. JVI.06349-11 pii: PMID: 22238313; PubMed Central PMCID: PMC3302331
    • Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, et al. Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane. J Virol. 2012; 86(6):2930–41. Epub 2012/01/13. JVI.06349-11 [pii] doi: 10.1128/ JVI.06349-11 PMID: 22238313; PubMed Central PMCID: PMC3302331.
    • (2012) J Virol , vol.86 , Issue.6 , pp. 2930-2941
    • Montero, M.1    Gulzar, N.2    Klaric, K.A.3    Donald, J.E.4    Lepik, C.5    Wu, S.6
  • 25
    • 84896737636 scopus 로고    scopus 로고
    • Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6
    • PMID: 24335316; PubMed Central PMCID: PMC3958054
    • Ofek G, Zirkle B, Yang Y, Zhu Z, McKee K, Zhang B, et al. Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6. J Virol. 2014; 88(5):2426–41. doi: 10.1128/JVI.02837-13 PMID: 24335316; PubMed Central PMCID: PMC3958054.
    • (2014) J Virol , vol.88 , Issue.5 , pp. 2426-2441
    • Ofek, G.1    Zirkle, B.2    Yang, Y.3    Zhu, Z.4    McKee, K.5    Zhang, B.6
  • 26
    • 84883597216 scopus 로고    scopus 로고
    • A universal virus-like particle-based vaccine for human papillomavirus: Longevity of protection and role of endogenous and exogenous adjuvants
    • PMID: 23933337; PubMed Central PMCID: PMC3785330
    • Tumban E, Peabody J, Peabody DS, Chackerian B. A universal virus-like particle-based vaccine for human papillomavirus: longevity of protection and role of endogenous and exogenous adjuvants. Vaccine. 2013; 31(41):4647–54. doi: 10.1016/j.vaccine.2013.07.052 PMID: 23933337; PubMed Central PMCID: PMC3785330.
    • (2013) Vaccine , vol.31 , Issue.41 , pp. 4647-4654
    • Tumban, E.1    Peabody, J.2    Peabody, D.S.3    Chackerian, B.4
  • 27
    • 80051615759 scopus 로고    scopus 로고
    • New insights into HIV assembly and trafficking
    • Epub 2011/08/16.: PMID: 21841072
    • Balasubramaniam M, Freed EO. New insights into HIV assembly and trafficking. Physiology (Bethesda). 2011; 26(4):236–51. Epub 2011/08/16. doi: 10.1152/physiol.00051.2010 PMID: 21841072.
    • (2011) Physiology (Bethesda) , vol.26 , Issue.4 , pp. 236-251
    • Balasubramaniam, M.1    Freed, E.O.2
  • 28
    • 0024429254 scopus 로고
    • Assembly and release of HIV-1 precursor Pr55gag virus-like particles from recombinant baculovirus-infected insect cells
    • PMID: 2676191
    • Gheysen D, Jacobs E, de Foresta F, Thiriart C, Francotte M, Thines D, et al. Assembly and release of HIV-1 precursor Pr55gag virus-like particles from recombinant baculovirus-infected insect cells. Cell. 1989; 59(1):103–12. PMID: 2676191.
    • (1989) Cell , vol.59 , Issue.1 , pp. 103-112
    • Gheysen, D.1    Jacobs, E.2    de Foresta, F.3    Thiriart, C.4    Francotte, M.5    Thines, D.6
  • 29
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • PMID: 12525643
    • Addo MM, Yu XG, Rathod A, Cohen D, Eldridge RL, Strick D, et al. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol. 2003; 77(3):2081–92. PMID: 12525643.
    • (2003) J Virol , vol.77 , Issue.3 , pp. 2081-2092
    • Addo, M.M.1    Yu, X.G.2    Rathod, A.3    Cohen, D.4    Eldridge, R.L.5    Strick, D.6
  • 30
    • 14844300825 scopus 로고    scopus 로고
    • Virus-like particles as HIV-1 vaccines
    • PMID: 15484204
    • Doan LX, Li M, Chen C, Yao Q. Virus-like particles as HIV-1 vaccines. Rev Med Virol. 2005; 15(2):75–88. PMID: 15484204.
    • (2005) Rev Med Virol , vol.15 , Issue.2 , pp. 75-88
    • Doan, L.X.1    Li, M.2    Chen, C.3    Yao, Q.4
  • 31
    • 33846101731 scopus 로고    scopus 로고
    • CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
    • PMID: 17173051
    • Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, et al. CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med. 2007; 13 (1):46–53. doi: 10.1038/nm1520 PMID: 17173051.
    • (2007) Nat Med , vol.13 , Issue.1 , pp. 46-53
    • Kiepiela, P.1    Ngumbela, K.2    Thobakgale, C.3    Ramduth, D.4    Honeyborne, I.5    Moodley, E.6
  • 32
    • 77954085035 scopus 로고    scopus 로고
    • Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV
    • PMID: 20531016; PubMed Central PMCID: PMC2930513
    • Hicar MD, Chen X, Briney B, Hammonds J, Wang JJ, Kalams S, et al. Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV. J Acquir Immune Defic Syndr. 2010; 54(3):223–35. doi: 10.1097/QAI. 0b013e3181dc98a3 PMID: 20531016; PubMed Central PMCID: PMC2930513.
    • (2010) J Acquir Immune Defic Syndr , vol.54 , Issue.3 , pp. 223-235
    • Hicar, M.D.1    Chen, X.2    Briney, B.3    Hammonds, J.4    Wang, J.J.5    Kalams, S.6
  • 33
    • 0034967872 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques
    • PMID: 11390589; PubMed Central PMCID: PMC114303
    • Montefiori DC, Safrit JT, Lydy SL, Barry AP, Bilska M, Vo HT, et al. Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques. J Virol. 2001; 75(13):5879–90. doi: 10.1128/JVI.75.13.5879-5890.2001 PMID: 11390589; PubMed Central PMCID: PMC114303.
    • (2001) J Virol , vol.75 , Issue.13 , pp. 5879-5890
    • Montefiori, D.C.1    Safrit, J.T.2    Lydy, S.L.3    Barry, A.P.4    Bilska, M.5    Vo, H.T.6
  • 34
    • 84951870546 scopus 로고    scopus 로고
    • Justification for the inclusion of Gag in HIV vaccine candidates
    • PMID: 26645951
    • Williamson AL, Rybicki EP. Justification for the inclusion of Gag in HIV vaccine candidates. Expert Rev Vaccines. 2015:1–14. doi: 10.1586/14760584.2016.1129904 PMID: 26645951.
    • (2015) Expert Rev Vaccines , pp. 1-14
    • Williamson, A.L.1    Rybicki, E.P.2
  • 35
    • 84927060257 scopus 로고    scopus 로고
    • Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease
    • PMID: 25453586
    • Zimran A, Gonzalez-Rodriguez DE, Abrahamov A, Elstein D, Paz A, Brill-Almon E, et al. Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease. Blood Cells Mol Dis. 2015; 54(1):9–16. doi: 10.1016/j.bcmd.2014.10.002 PMID: 25453586.
    • (2015) Blood Cells Mol Dis , vol.54 , Issue.1 , pp. 9-16
    • Zimran, A.1    Gonzalez-Rodriguez, D.E.2    Abrahamov, A.3    Elstein, D.4    Paz, A.5    Brill-Almon, E.6
  • 36
    • 84912116176 scopus 로고    scopus 로고
    • Fighting Ebola with ZMapp: Spotlight on plant-made antibody
    • PMID: 25218825
    • Zhang Y, Li D, Jin X, Huang Z. Fighting Ebola with ZMapp: spotlight on plant-made antibody. Science China Life sciences. 2014; 57(10):987–8. doi: 10.1007/s11427-014-4746-7 PMID: 25218825.
    • (2014) Science China Life Sciences , vol.57 , Issue.10 , pp. 987-988
    • Zhang, Y.1    Li, D.2    Jin, X.3    Huang, Z.4
  • 37
    • 84912539210 scopus 로고    scopus 로고
    • Clinical care of two patients with Ebola virus disease in the United States
    • PMID: 25390460
    • Lyon GM, Mehta AK, Varkey JB, Brantly K, Plyler L, McElroy AK, et al. Clinical care of two patients with Ebola virus disease in the United States. N Engl J Med. 2014; 371(25):2402–9. doi: 10.1056/ NEJMoa1409838 PMID: 25390460.
    • (2014) N Engl J Med , vol.371 , Issue.25 , pp. 2402-2409
    • Lyon, G.M.1    Mehta, A.K.2    Varkey, J.B.3    Brantly, K.4    Plyler, L.5    McElroy, A.K.6
  • 38
    • 84925581190 scopus 로고    scopus 로고
    • As Ebola epidemic begins to slow, trials of drugs and vaccines speed up
    • PMID: 25671623
    • Kuehn BM. As Ebola Epidemic Begins to Slow, Trials of Drugs and Vaccines Speed Up. JAMA. 2015. doi: 10.1001/jama.2015.0942 PMID: 25671623.
    • (2015) JAMA
    • Kuehn, B.M.1
  • 39
    • 84936865223 scopus 로고    scopus 로고
    • Plant-based vaccines against viruses
    • PMID: 25465382; PubMed Central PMCID: PMC4264547
    • Rybicki EP. Plant-based vaccines against viruses. Virology journal. 2014; 11(1):205. doi: 10.1186/ s12985-014-0205-0 PMID: 25465382; PubMed Central PMCID: PMC4264547.
    • (2014) Virology Journal , vol.11 , Issue.1 , pp. 205
    • Rybicki, E.P.1
  • 40
    • 84881024740 scopus 로고    scopus 로고
    • Biological and biochemical characterization of HIV-1 Gag/ dgp41 virus-like particles expressed in Nicotiana benthamiana
    • PMID: 23506331
    • Kessans SA, Linhart MD, Matoba N, Mor T. Biological and biochemical characterization of HIV-1 Gag/ dgp41 virus-like particles expressed in Nicotiana benthamiana. Plant Biotechnology Journal. 2013; 11 (6):681–90. doi: 10.1111/pbi.12058 PMID: 23506331
    • (2013) Plant Biotechnology Journal , vol.11 , Issue.6 , pp. 681-690
    • Kessans, S.A.1    Linhart, M.D.2    Matoba, N.3    Mor, T.4
  • 41
    • 47749107594 scopus 로고    scopus 로고
    • Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes
    • PMID: 18473785
    • Matoba N, Griffin TA, Mittman M, Doran JD, Alfsen A, Montefiori DC, et al. Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes. Curr HIV Res. 2008; 6(3):218–29. PMID: 18473785.
    • (2008) Curr HIV Res , vol.6 , Issue.3 , pp. 218-229
    • Matoba, N.1    Griffin, T.A.2    Mittman, M.3    Doran, J.D.4    Alfsen, A.5    Montefiori, D.C.6
  • 42
    • 0035813390 scopus 로고    scopus 로고
    • Expression of recombinant human acetylcholinesterase in transgenic tomato plants
    • PMID: 11590598
    • Mor TS, Sternfeld M, Soreq H, Arntzen CJ, Mason HS. Expression of recombinant human acetylcholinesterase in transgenic tomato plants. Biotechnol Bioeng. 2001; 75(3):259–66. PMID: 11590598.
    • (2001) Biotechnol Bioeng , vol.75 , Issue.3 , pp. 259-266
    • Mor, T.S.1    Sternfeld, M.2    Soreq, H.3    Arntzen, C.J.4    Mason, H.S.5
  • 44
    • 77951630373 scopus 로고    scopus 로고
    • GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium
    • Epub 2010/03/09.: PMID: 20208001; PubMed Central PMCID: PMC3731077
    • Shen R, Drelichman ER, Bimczok D, Ochsenbauer C, Kappes JC, Cannon JA, et al. GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium. J Immunol. 2010; 184(7):3648–55. Epub 2010/03/09. doi: 10.4049/jimmunol.0903346 PMID: 20208001; PubMed Central PMCID: PMC3731077.
    • (2010) J Immunol , vol.184 , Issue.7 , pp. 3648-3655
    • Shen, R.1    Drelichman, E.R.2    Bimczok, D.3    Ochsenbauer, C.4    Kappes, J.C.5    Cannon, J.A.6
  • 45
    • 0034759882 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
    • PMID: 11602729; PubMed Central PMCID: PMC114669
    • Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, et al. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol. 2001; 75(22):10892–905. doi: 10.1128/JVI.75.22.10892-10905.2001 PMID: 11602729; PubMed Central PMCID: PMC114669.
    • (2001) J Virol , vol.75 , Issue.22 , pp. 10892-10905
    • Zwick, M.B.1    Labrijn, A.F.2    Wang, M.3    Spenlehauer, C.4    Saphire, E.O.5    Binley, J.M.6
  • 46
    • 69249086612 scopus 로고    scopus 로고
    • HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: An IgA gene and functional analysis
    • Epub 2009/07/10. mi200989 pii: PMID: 19587640
    • Tudor D, Derrien M, Diomede L, Drillet AS, Houimel M, Moog C, et al. HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis. Mucosal Immunol. 2009; 2(5):412–26. Epub 2009/07/10. mi200989 [pii] doi: 10.1038/mi.2009.89 PMID: 19587640.
    • (2009) Mucosal Immunol , vol.2 , Issue.5 , pp. 412-426
    • Tudor, D.1    Derrien, M.2    Diomede, L.3    Drillet, A.S.4    Houimel, M.5    Moog, C.6
  • 47
    • 79953736960 scopus 로고    scopus 로고
    • The broadly neutralizing HIV-1 IgG 2F5 elicits gp41-specific antibody-dependent cell cytotoxicity in a FcgammaRI-dependent manner
    • PMID: 21330910
    • Tudor D, Bomsel M. The broadly neutralizing HIV-1 IgG 2F5 elicits gp41-specific antibody-dependent cell cytotoxicity in a FcgammaRI-dependent manner. AIDS. 2011; 25(6):751–9. doi: 10.1097/QAD. 0b013e32834507bd PMID: 21330910.
    • (2011) AIDS , vol.25 , Issue.6 , pp. 751-759
    • Tudor, D.1    Bomsel, M.2
  • 48
    • 82455210416 scopus 로고    scopus 로고
    • Mucosal antibodies induced by tandem repeat of 2F5 epitope block transcytosis of HIV-1
    • Epub 2011/09/24.: PMID: 21939723
    • Wang J, Xu L, Tong P, Chen YH. Mucosal antibodies induced by tandem repeat of 2F5 epitope block transcytosis of HIV-1. Vaccine. 2011; 29(47):8542–8. Epub 2011/09/24. doi: 10.1016/j.vaccine.2011. 09.032 PMID: 21939723.
    • (2011) Vaccine , vol.29 , Issue.47 , pp. 8542-8548
    • Wang, J.1    Xu, L.2    Tong, P.3    Chen, Y.H.4
  • 49
    • 84857195490 scopus 로고    scopus 로고
    • Prime boost vaccination approaches with different conjugates of a new HIV-1 gp41 epitope encompassing the membrane proximal external region induce neutralizing antibodies in mice
    • Epub 2012/ 01/25. pii: PMID: 22269872
    • Zhou M, Kostoula I, Brill B, Panou E, Sakarellos-Daitsiotis M, Dietrich U. Prime boost vaccination approaches with different conjugates of a new HIV-1 gp41 epitope encompassing the membrane proximal external region induce neutralizing antibodies in mice. Vaccine. 2012; 30(11):1911–6. Epub 2012/ 01/25. S0264-410X(12)00041-2 [pii] doi: 10.1016/j.vaccine.2012.01.026 PMID: 22269872.
    • (2012) Vaccine , vol.30 , Issue.11 , pp. 1911-1916
    • Zhou, M.1    Kostoula, I.2    Brill, B.3    Panou, E.4    Sakarellos-Daitsiotis, M.5    Dietrich, U.6
  • 50
    • 79960563686 scopus 로고    scopus 로고
    • Humoral immunogenicity of an HIV-1 envelope residue 649–684 membrane-proximal region peptide fused to the plague antigen F1-V
    • Epub 2011/06/23. pii: PMID: 21693158; PubMed Central PMCID: PMC3152316
    • Matoba N, Shah NR, Mor TS. Humoral immunogenicity of an HIV-1 envelope residue 649–684 membrane-proximal region peptide fused to the plague antigen F1-V. Vaccine. 2011; 29(34):5584–90. Epub 2011/06/23. S0264-410X(11)00871-1 [pii] doi: 10.1016/j.vaccine.2011.06.007 PMID: 21693158; PubMed Central PMCID: PMC3152316.
    • (2011) Vaccine , vol.29 , Issue.34 , pp. 5584-5590
    • Matoba, N.1    Shah, N.R.2    Mor, T.S.3
  • 51
    • 84883348588 scopus 로고    scopus 로고
    • Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: Selection against membrane proximal external region-associated autoreactivity limits T-dependent responses
    • Epub 2013/08/07.: PMID: 23918977; PubMed Central PMCID: PMC3870053
    • Verkoczy L, Chen Y, Zhang J, Bouton-Verville H, Newman A, Lockwood B, et al. Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses. Journal of immunology. 2013; 191 (5):2538–50. Epub 2013/08/07. doi: 10.4049/jimmunol.1300971 PMID: 23918977; PubMed Central PMCID: PMC3870053.
    • (2013) Journal of Immunology , vol.191 , Issue.5 , pp. 2538-2550
    • Verkoczy, L.1    Chen, Y.2    Zhang, J.3    Bouton-Verville, H.4    Newman, A.5    Lockwood, B.6
  • 52
    • 79951754740 scopus 로고    scopus 로고
    • Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges
    • Epub 2011/02/15. S1074-7613(11)00036-7 pii: PMID: 21315623
    • Bomsel M, Tudor D, Drillet AS, Alfsen A, Ganor Y, Roger MG, et al. Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges. Immunity. 2011; 34(2):269–80. Epub 2011/02/15. S1074-7613(11)00036-7 [pii] doi: 10. 1016/j.immuni.2011.01.015 PMID: 21315623.
    • (2011) Immunity , vol.34 , Issue.2 , pp. 269-280
    • Bomsel, M.1    Tudor, D.2    Drillet, A.S.3    Alfsen, A.4    Ganor, Y.5    Roger, M.G.6
  • 53
    • 41649090223 scopus 로고    scopus 로고
    • A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
    • Epub 2008/ 03/07.: PMID: 18322015; PubMed Central PMCID: PMC2268799
    • Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, Chen B. A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies. P Natl Acad Sci USA. 2008; 105(10):3739–44. Epub 2008/ 03/07. doi: 10.1073/pnas.0800255105 PMID: 18322015; PubMed Central PMCID: PMC2268799.
    • (2008) P Natl Acad Sci USA , vol.105 , Issue.10 , pp. 3739-3744
    • Frey, G.1    Peng, H.2    Rits-Volloch, S.3    Morelli, M.4    Cheng, Y.5    Chen, B.6
  • 54
    • 84900317748 scopus 로고    scopus 로고
    • AIDS/HIV. Host controls of HIV neutralizing antibodies
    • PMID: 24812389; PubMed Central PMCID: PMC4162091
    • Haynes BF, Verkoczy L. AIDS/HIV. Host controls of HIV neutralizing antibodies. Science. 2014; 344 (6184):588–9. doi: 10.1126/science.1254990 PMID: 24812389; PubMed Central PMCID: PMC4162091.
    • (2014) Science , vol.344 , Issue.6184 , pp. 588-589
    • Haynes, B.F.1    Verkoczy, L.2
  • 55
    • 84942884607 scopus 로고    scopus 로고
    • Biophysical characterization of a vaccine candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion
    • PMID: 26295457; PubMed Central PMCID: PMCPMC4546420
    • Gong Z, Martin-Garcia JM, Daskalova SM, Craciunescu FM, Song L, Dorner K, et al. Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion. PLoS One. 2015; 10(8):e0136507. doi: 10.1371/journal.pone.0136507 PMID: 26295457; PubMed Central PMCID: PMCPMC4546420.
    • (2015) PLoS One , vol.10 , Issue.8
    • Gong, Z.1    Martin-Garcia, J.M.2    Daskalova, S.M.3    Craciunescu, F.M.4    Song, L.5    Dorner, K.6
  • 56
    • 35448941978 scopus 로고    scopus 로고
    • Advances in methods for the production, purification, and characterization of HIV-1 Gag-Env pseudovirion vaccines
    • PMID: 17936444
    • Hammonds J, Chen X, Zhang X, Lee F, Spearman P. Advances in methods for the production, purification, and characterization of HIV-1 Gag-Env pseudovirion vaccines. Vaccine. 2007; 25(47):8036–48. doi: 10.1016/j.vaccine.2007.09.016 PMID: 17936444.
    • (2007) Vaccine , vol.25 , Issue.47 , pp. 8036-8048
    • Hammonds, J.1    Chen, X.2    Zhang, X.3    Lee, F.4    Spearman, P.5
  • 57
    • 77953987341 scopus 로고    scopus 로고
    • Plant-made vaccines for humans and animals
    • Epub 2010/03/18. PBI507 pii: PMID: 20233333
    • Rybicki EP. Plant-made vaccines for humans and animals. Plant Biotechnol J. 2010; 8(5):620–37. Epub 2010/03/18. PBI507 [pii] doi: 10.1111/j.1467-7652.2010.00507.x PMID: 20233333.
    • (2010) Plant Biotechnol J , vol.8 , Issue.5 , pp. 620-637
    • Rybicki, E.P.1
  • 58
    • 84907263545 scopus 로고    scopus 로고
    • Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
    • PMID: 25171469; PubMed Central PMCID: PMC4214273
    • Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature. 2014; 514(7520):47–53. doi: 10.1038/nature13777 PMID: 25171469; PubMed Central PMCID: PMC4214273.
    • (2014) Nature , vol.514 , Issue.7520 , pp. 47-53
    • Qiu, X.1    Wong, G.2    Audet, J.3    Bello, A.4    Fernando, L.5    Alimonti, J.B.6
  • 59
    • 84912064043 scopus 로고    scopus 로고
    • US signs contract with ZMapp maker to accelerate development of the Ebola drug
    • PMID: 25189475
    • McCarthy M. US signs contract with ZMapp maker to accelerate development of the Ebola drug. Bmj. 2014; 349:g5488. doi: 10.1136/bmj.g5488 PMID: 25189475.
    • (2014) Bmj , vol.349 , pp. g5488
    • McCarthy, M.1
  • 61
    • 67650156117 scopus 로고    scopus 로고
    • A DNA replicon system for rapid high-level production of virus-like particles in plants
    • Epub 2009/ 03/25.: PMID: 19309755; PubMed Central PMCID: PMC2704498
    • Huang Z, Chen Q, Hjelm B, Arntzen C, Mason H. A DNA replicon system for rapid high-level production of virus-like particles in plants. Biotechnology and bioengineering. 2009; 103(4):706–14. Epub 2009/ 03/25. doi: 10.1002/bit.22299 PMID: 19309755; PubMed Central PMCID: PMC2704498.
    • (2009) Biotechnology and Bioengineering , vol.103 , Issue.4 , pp. 706-714
    • Huang, Z.1    Chen, Q.2    Hjelm, B.3    Arntzen, C.4    Mason, H.5
  • 62
    • 40849140609 scopus 로고    scopus 로고
    • An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles
    • Epub 2008/03/08.: PMID: 18325641; PubMed Central PMCID: PMC2744496
    • Santi L, Batchelor L, Huang Z, Hjelm B, Kilbourne J, Arntzen CJ, et al. An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles. Vaccine. 2008; 26(15):1846–54. Epub 2008/03/08. doi: 10.1016/j.vaccine.2008.01.053 PMID: 18325641; PubMed Central PMCID: PMC2744496.
    • (2008) Vaccine , vol.26 , Issue.15 , pp. 1846-1854
    • Santi, L.1    Batchelor, L.2    Huang, Z.3    Hjelm, B.4    Kilbourne, J.5    Arntzen, C.J.6
  • 63
    • 33745085830 scopus 로고    scopus 로고
    • Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein
    • Epub 2006/12/21.: PMID: 17177807
    • Zhang X, Buehner NA, Hutson AM, Estes MK, Mason HS. Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein. Plant biotechnology journal. 2006; 4(4):419–32. Epub 2006/12/21. doi: 10.1111/j.1467-7652.2006.00191.x PMID: 17177807.
    • (2006) Plant Biotechnology Journal , vol.4 , Issue.4 , pp. 419-432
    • Zhang, X.1    Buehner, N.A.2    Hutson, A.M.3    Estes, M.K.4    Mason, H.S.5
  • 64
    • 77953964469 scopus 로고    scopus 로고
    • The production of hemagglutinin-based virus-like particles in plants: A rapid, efficient and safe response to pandemic influenza
    • Epub 2010/03/05.: PMID: 20199612
    • D'Aoust MA, Couture MM, Charland N, Trepanier S, Landry N, Ors F, et al. The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza. Plant biotechnology journal. 2010; 8(5):607–19. Epub 2010/03/05. doi: 10.1111/j.1467-7652.2009. 00496.x PMID: 20199612.
    • (2010) Plant Biotechnology Journal , vol.8 , Issue.5 , pp. 607-619
    • D'Aoust, M.A.1    Couture, M.M.2    Charland, N.3    Trepanier, S.4    Landry, N.5    Ors, F.6
  • 65
    • 46949110898 scopus 로고    scopus 로고
    • Expression of HIV-1 antigens in plants as potential subunit vaccines
    • PMID: 18573204; PubMed Central PMCID: PMC2443125
    • Meyers A, Chakauya E, Shephard E, Tanzer FL, Maclean J, Lynch A, et al. Expression of HIV-1 antigens in plants as potential subunit vaccines. BMC Biotechnol. 2008; 8:53. doi: 10.1186/1472-6750-8-53 PMID: 18573204; PubMed Central PMCID: PMC2443125.
    • (2008) BMC Biotechnol , vol.8 , pp. 53
    • Meyers, A.1    Chakauya, E.2    Shephard, E.3    Tanzer, F.L.4    Maclean, J.5    Lynch, A.6
  • 66
    • 63349105635 scopus 로고    scopus 로고
    • High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts
    • PMID: 19234717.
    • Scotti N, Alagna F, Ferraiolo E, Formisano G, Sannino L, Buonaguro L, et al. High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts. Planta. 2009; 229(5):1109–22. PMID: 19234717. doi: 10.1007/s00425-009-0898-2
    • (2009) Planta , vol.229 , Issue.5 , pp. 1109-1122
    • Scotti, N.1    Alagna, F.2    Ferraiolo, E.3    Formisano, G.4    Sannino, L.5    Buonaguro, L.6
  • 67
    • 48449103933 scopus 로고    scopus 로고
    • Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration
    • Epub 2008/07/08. pii: PMID: 18601967
    • Guetard D, Greco R, Cervantes Gonzalez M, Celli S, Kostrzak A, Langlade-Demoyen P, et al. Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration. Vaccine. 2008; 26 (35):4477–85. Epub 2008/07/08. S0264-410X(08)00806-2 [pii] doi: 10.1016/j.vaccine.2008.06.059 PMID: 18601967.
    • (2008) Vaccine , vol.26 , Issue.35 , pp. 4477-4485
    • Guetard, D.1    Greco, R.2    Cervantes Gonzalez, M.3    Celli, S.4    Kostrzak, A.5    Langlade-Demoyen, P.6
  • 68
    • 4644329653 scopus 로고    scopus 로고
    • Preserved antigenicity of HIV-1 p24 produced and purified in high yields from plants inoculated with a tobacco mosaic virus (TMV)-derived vector
    • Epub 2004/09/24.: PMID: 15381357
    • Perez-Filgueira DM, Brayfield BP, Phiri S, Borca MV, Wood C, Morris TJ. Preserved antigenicity of HIV-1 p24 produced and purified in high yields from plants inoculated with a tobacco mosaic virus (TMV)-derived vector. Journal of virological methods. 2004; 121(2):201–8. Epub 2004/09/24. doi: 10. 1016/j.jviromet.2004.06.022 PMID: 15381357.
    • (2004) Journal of Virological Methods , vol.121 , Issue.2 , pp. 201-208
    • Perez-Filgueira, D.M.1    Brayfield, B.P.2    Phiri, S.3    Borca, M.V.4    Wood, C.5    Morris, T.J.6
  • 69
    • 79955652900 scopus 로고    scopus 로고
    • Immunogenicity of chloroplast-derived HIV-1 p24 and a p24-Nef fusion protein following subcutaneous and oral administration in mice
    • Epub 2011/03/30.: PMID: 21443546
    • Gonzalez-Rabade N, McGowan EG, Zhou F, McCabe MS, Bock R, Dix PJ, et al. Immunogenicity of chloroplast-derived HIV-1 p24 and a p24-Nef fusion protein following subcutaneous and oral administration in mice. Plant biotechnology journal. 2011; 9(6):629–38. Epub 2011/03/30. doi: 10.1111/j.1467-7652.2011.00609.x PMID: 21443546.
    • (2011) Plant Biotechnology Journal , vol.9 , Issue.6 , pp. 629-638
    • Gonzalez-Rabade, N.1    McGowan, E.G.2    Zhou, F.3    McCabe, M.S.4    Bock, R.5    Dix, P.J.6
  • 70
    • 58149142623 scopus 로고    scopus 로고
    • Feeding of mice with Arabidopsis thaliana expressing the HIV-1 subtype C p24 antigen gives rise to systemic immune responses
    • Epub 2009/01/10.: PMID: 19132995
    • Lindh I, Kalbina I, Thulin S, Scherbak N, Savenstrand H, Brave A, et al. Feeding of mice with Arabidopsis thaliana expressing the HIV-1 subtype C p24 antigen gives rise to systemic immune responses. Apmis. 2008; 116(11):985–94. Epub 2009/01/10. doi: 10.1111/j.1600-0463.2008.00900.x PMID: 19132995.
    • (2008) Apmis , vol.116 , Issue.11 , pp. 985-994
    • Lindh, I.1    Kalbina, I.2    Thulin, S.3    Scherbak, N.4    Savenstrand, H.5    Brave, A.6
  • 71
    • 0031792544 scopus 로고    scopus 로고
    • Intranasal immunization with a plant virus expressing a peptide from HIV-1 gp41 stimulates better mucosal and systemic HIV-1specific IgA and IgG than oral immunization
    • PMID: 9839930
    • Durrani Z, McInerney TL, McLain L, Jones T, Bellaby T, Brennan FR, et al. Intranasal immunization with a plant virus expressing a peptide from HIV-1 gp41 stimulates better mucosal and systemic HIV-1specific IgA and IgG than oral immunization. J Immunol Methods. 1998; 220(1–2):93–103. PMID: 9839930.
    • (1998) J Immunol Methods , vol.220 , Issue.1-2 , pp. 93-103
    • Durrani, Z.1    McInerney, T.L.2    McLain, L.3    Jones, T.4    Bellaby, T.5    Brennan, F.R.6
  • 72
    • 0034881226 scopus 로고    scopus 로고
    • Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1
    • PMID: 11507188
    • Marusic C, Rizza P, Lattanzi L, Mancini C, Spada M, Belardelli F, et al. Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1. J Virol. 2001; 75(18):8434–9. PMID: 11507188.
    • (2001) J Virol , vol.75 , Issue.18 , pp. 8434-8439
    • Marusic, C.1    Rizza, P.2    Lattanzi, L.3    Mancini, C.4    Spada, M.5    Belardelli, F.6
  • 74
    • 0033577298 scopus 로고    scopus 로고
    • Analysis of the ability of five adjuvants to enhance immune responses to a chimeric plant virus displaying an HIV-1 peptide
    • PMID: 10195771
    • McInerney TL, Brennan FR, Jones TD, Dimmock NJ. Analysis of the ability of five adjuvants to enhance immune responses to a chimeric plant virus displaying an HIV-1 peptide. Vaccine. 1999; 17(11–12):1359–68. PMID: 10195771.
    • (1999) Vaccine , vol.17 , Issue.11-12 , pp. 1359-1368
    • McInerney, T.L.1    Brennan, F.R.2    Jones, T.D.3    Dimmock, N.J.4
  • 75
    • 0030175998 scopus 로고    scopus 로고
    • Stimulation of neutralizing antibodies to human immunodeficiency virus type 1 in three strains of mice immunized with a 22 amino acid peptide of gp41 expressed on the surface of a plant virus
    • PMID: 8817828
    • McLain L, Durrani Z, Wisniewski LA, Porta C, Lomonossoff GP, Dimmock NJ. Stimulation of neutralizing antibodies to human immunodeficiency virus type 1 in three strains of mice immunized with a 22 amino acid peptide of gp41 expressed on the surface of a plant virus. Vaccine. 1996; 14(8):799–810. PMID: 8817828.
    • (1996) Vaccine , vol.14 , Issue.8 , pp. 799-810
    • McLain, L.1    Durrani, Z.2    Wisniewski, L.A.3    Porta, C.4    Lomonossoff, G.P.5    Dimmock, N.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.