메뉴 건너뛰기




Volumn 340, Issue 6136, 2013, Pages

Accelerating next-generation vaccine development for global disease prevention

Author keywords

[No Author keywords available]

Indexed keywords

MEASLES VACCINE; PATTERN RECOGNITION RECEPTOR; SMALLPOX VACCINE; TOLL LIKE RECEPTOR; VACCINE; WART VIRUS VACCINE; ANTIGEN; IMMUNOLOGICAL ADJUVANT;

EID: 84878356025     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1232910     Document Type: Review
Times cited : (237)

References (87)
  • 2
    • 0005214107 scopus 로고
    • De l'attenuation du virus du choléra des poules
    • L. Pasteur, De l'attenuation du virus du choléra des poules. CR Acad. Sci. Paris. 91, 673 (1880).
    • (1880) CR Acad. Sci. Paris , vol.91 , pp. 673
    • Pasteur, L.1
  • 3
    • 0039588962 scopus 로고
    • On a new method of producing immunity from contagious diseases
    • D. Salmon, T. Smith, On a new method of producing immunity from contagious diseases. American Vet. Review. 10, 63 (1886).
    • (1886) American Vet. Review , vol.10 , pp. 63
    • Salmon, D.1    Smith, T.2
  • 4
    • 0002963116 scopus 로고
    • Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues
    • doi: 10.1126/science.109.2822.85; pmid: 17794160
    • J. F. Enders, T. H. Weller, F. C. Robbins, Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues. Science 109, 85 (1949). doi: 10.1126/science.109.2822.85; pmid: 17794160
    • (1949) Science , vol.109 , pp. 85
    • Enders, J.F.1    Weller, T.H.2    Robbins, F.C.3
  • 5
    • 0014252463 scopus 로고
    • Live, attenuated mumps-virus vaccine
    • doi: 10.1056/NEJM196802012780501; pmid: 4169706
    • M. R. Hilleman, E. B. Buynak, R. E. Weibel, J. Stokes Jr., Live, attenuated mumps-virus vaccine. N. Engl. J. Med. 278, 227 (1968). doi: 10.1056/NEJM196802012780501; pmid: 4169706
    • (1968) N. Engl. J. Med. , vol.278 , pp. 227
    • Hilleman, M.R.1    Buynak, E.B.2    Weibel, R.E.3    Stokes Jr., J.4
  • 6
    • 0014555736 scopus 로고
    • Attenuation of RA 27-3 rubella virus in WI-38 human diploid cells
    • pmid: 5794813
    • S. A. Plotkin, J. D. Farquhar, M. Katz, F. Buser, Attenuation of RA 27-3 rubella virus in WI-38 human diploid cells. Am. J. Dis. Child. 118, 178 (1969). pmid: 5794813
    • (1969) Am. J. Dis. Child. , vol.118 , pp. 178
    • Plotkin, S.A.1    Farquhar, J.D.2    Katz, M.3    Buser, F.4
  • 7
    • 0042876315 scopus 로고
    • Studies on variants of poliomyelitis virus. I. Experimental segregation and properties of avirulent variants of three immunologic types
    • doi: 10.1084/jem.99.6.551; pmid: 13163327
    • A. B. Sabin, W. A. Hennessen, J. Winsser, Studies on variants of poliomyelitis virus. I. Experimental segregation and properties of avirulent variants of three immunologic types. J. Exp. Med. 99, 551 (1954). doi: 10.1084/jem.99.6.551; pmid: 13163327
    • (1954) J. Exp. Med. , vol.99 , pp. 551
    • Sabin, A.B.1    Hennessen, W.A.2    Winsser, J.3
  • 8
    • 0343782058 scopus 로고
    • Formaldehyde treatment and safety testing of experimental poliomyelitis vaccines
    • doi: 10.2105/AJPH.44.5.563; pmid: 13148396
    • J. E. Salk et al., Formaldehyde treatment and safety testing of experimental poliomyelitis vaccines. Am. J. Public Health Nations Health 44, 563 (1954). doi: 10.2105/AJPH.44.5.563; pmid: 13148396
    • (1954) Am. J. Public Health Nations Health , vol.44 , pp. 563
    • Salk, J.E.1
  • 9
    • 0014414212 scopus 로고
    • Development and evaluation of the Moraten measles virus vaccine
    • doi: 10.1001/jama.1968.03150030043009; pmid: 5695578
    • M. R. Hilleman et al., Development and evaluation of the Moraten measles virus vaccine. JAMA 206, 587 (1968). doi: 10.1001/jama.1968.03150030043009; pmid: 5695578
    • (1968) JAMA , vol.206 , pp. 587
    • Hilleman, M.R.1
  • 10
    • 0034063425 scopus 로고    scopus 로고
    • Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children
    • Northern California Kaiser Permanente Vaccine Study Center Group, doi: 10.1097/00006454-200003000-00003; pmid: 10749457
    • S. Black et al.; Northern California Kaiser Permanente Vaccine Study Center Group, Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Pediatr. Infect. Dis. J. 19, 187 (2000). doi: 10.1097/00006454-200003000-00003; pmid: 10749457
    • (2000) Pediatr. Infect. Dis. J. , vol.19 , pp. 187
    • Black, S.1
  • 11
    • 33645746829 scopus 로고    scopus 로고
    • Who invented the VLP cervical cancer vaccines?
    • doi: 10.1093/jnci/djj144; pmid: 16595773
    • C. McNeil, Who invented the VLP cervical cancer vaccines? J. Natl. Cancer Inst. 98, 433 (2006). doi: 10.1093/jnci/djj144; pmid: 16595773
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 433
    • McNeil, C.1
  • 12
    • 0018955097 scopus 로고
    • Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates
    • doi: 10.1084/jem.152.2.361; pmid: 6967514
    • R. Schneerson, O. Barrera, A. Sutton, J. B. Robbins, Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates. J. Exp. Med. 152, 361 (1980). doi: 10.1084/jem.152.2.361; pmid: 6967514
    • (1980) J. Exp. Med. , vol.152 , pp. 361
    • Schneerson, R.1    Barrera, O.2    Sutton, A.3    Robbins, J.B.4
  • 13
    • 77958451546 scopus 로고    scopus 로고
    • A decade of vaccines: Integrating immunology and vaccinology for rational vaccine design
    • doi: 10.1016/j.immuni.2010.10.011; pmid: 21029955
    • D. A. D'Argenio, C. B. Wilson, A decade of vaccines: Integrating immunology and vaccinology for rational vaccine design. Immunity 33, 437 (2010). doi: 10.1016/j.immuni.2010.10.011; pmid: 21029955
    • (2010) Immunity , vol.33 , pp. 437
    • D'Argenio, D.A.1    Wilson, C.B.2
  • 14
    • 0348078311 scopus 로고    scopus 로고
    • The value of vaccination: A global perspective
    • doi: 10.1016/S0264-410X(03)00377-3; pmid: 14505886
    • J. Ehreth, The value of vaccination: A global perspective. Vaccine 21, 4105 (2003). doi: 10.1016/S0264-410X(03)00377-3; pmid: 14505886
    • (2003) Vaccine , vol.21 , pp. 4105
    • Ehreth, J.1
  • 15
    • 84878347730 scopus 로고    scopus 로고
    • S. A. Plotkin, W. A. Orenstein, P. A. Offit, Eds. Saunders, Philadelphia
    • M. A. Miller, A. R. Hinman, in Vaccines, S. A. Plotkin, W. A. Orenstein, P. A. Offit, Eds. (Saunders, Philadelphia, 2008), pp. 1594-1610.
    • (2008) Vaccines , pp. 1594-1610
    • Miller, M.A.1    Hinman, A.R.2
  • 16
    • 33748366332 scopus 로고    scopus 로고
    • Immunopathological mechanisms in dengue and dengue hemorrhagic fever
    • doi: 10.1097/01.qco.0000244047.31135.fa; pmid: 16940865
    • S. Green, A. Rothman, Immunopathological mechanisms in dengue and dengue hemorrhagic fever. Curr. Opin. Infect. Dis. 19, 429 (2006). doi: 10.1097/01.qco.0000244047.31135.fa; pmid: 16940865
    • (2006) Curr. Opin. Infect. Dis. , vol.19 , pp. 429
    • Green, S.1    Rothman, A.2
  • 17
    • 77958492018 scopus 로고    scopus 로고
    • From vaccines to memory and back
    • doi: 10.1016/j.immuni.2010.10.008; pmid: 21029957
    • F. Sallusto, A. Lanzavecchia, K. Araki, R. Ahmed, From vaccines to memory and back. Immunity 33, 451 (2010). doi: 10.1016/j.immuni.2010.10.008; pmid: 21029957
    • (2010) Immunity , vol.33 , pp. 451
    • Sallusto, F.1    Lanzavecchia, A.2    Araki, K.3    Ahmed, R.4
  • 18
    • 77958490167 scopus 로고    scopus 로고
    • Induction of immunity to human immunodeficiency virus type-1 by vaccination
    • doi: 10.1016/j.immuni.2010.09.011; pmid: 21029964
    • M. J. McElrath, B. F. Haynes, Induction of immunity to human immunodeficiency virus type-1 by vaccination. Immunity 33, 542 (2010). doi: 10.1016/j.immuni.2010.09.011; pmid: 21029964
    • (2010) Immunity , vol.33 , pp. 542
    • McElrath, M.J.1    Haynes, B.F.2
  • 19
    • 37349033017 scopus 로고    scopus 로고
    • Drugs versus bugs: In pursuit of the persistent predator Mycobacterium tuberculosis
    • doi: 10.1038/nrmicro1816; pmid: 18079742
    • J. C. Sacchettini, E. J. Rubin, J. S. Freundlich, Drugs versus bugs: In pursuit of the persistent predator Mycobacterium tuberculosis. Nat. Rev. Microbiol. 6, 41 (2008). doi: 10.1038/nrmicro1816; pmid: 18079742
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 41
    • Sacchettini, J.C.1    Rubin, E.J.2    Freundlich, J.S.3
  • 20
    • 84878370616 scopus 로고    scopus 로고
    • S. A. Plotkin, W. Orenstein, P. A. Offit, Eds. W.B. Saunders, London
    • C.-A. Siegrist, in Vaccines: Sixth Edition, S. A. Plotkin, W. Orenstein, P. A. Offit, Eds. (W.B. Saunders, London, 2013), pp. 14-32.
    • (2013) Vaccines: Sixth Edition , pp. 14-32
    • Siegrist, C.-A.1
  • 21
    • 67650453747 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 elite neutralizers: Individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
    • doi: 10.1128/JVI.00110-09; pmid: 19439467
    • M. D. Simek et al., Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J. Virol. 83, 7337 (2009). doi: 10.1128/JVI.00110-09; pmid: 19439467
    • (2009) J. Virol. , vol.83 , pp. 7337
    • Simek, M.D.1
  • 22
    • 84867630116 scopus 로고    scopus 로고
    • A blueprint for HIV vaccine discovery
    • doi: 10.1016/j.chom.2012.09.008; pmid: 23084910
    • D. R. Burton et al., A blueprint for HIV vaccine discovery. Cell Host Microbe 12, 396 (2012). doi: 10.1016/j.chom.2012.09.008; pmid: 23084910
    • (2012) Cell Host Microbe , vol.12 , pp. 396
    • Burton, D.R.1
  • 23
    • 84860759632 scopus 로고    scopus 로고
    • B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
    • doi: 10.1038/nbt.2197; pmid: 22565972
    • B. F. Haynes, G. Kelsoe, S. C. Harrison, T. B. Kepler, B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat. Biotechnol. 30, 423 (2012). doi: 10.1038/nbt.2197; pmid: 22565972
    • (2012) Nat. Biotechnol. , vol.30 , pp. 423
    • Haynes, B.F.1    Kelsoe, G.2    Harrison, S.C.3    Kepler, T.B.4
  • 24
    • 0033787577 scopus 로고    scopus 로고
    • Reverse vaccinology
    • doi: 10.1016/S1369-5274(00)00119-3; pmid: 11050440
    • R. Rappuoli, Reverse vaccinology. Curr. Opin. Microbiol. 3, 445 (2000). doi: 10.1016/S1369-5274(00)00119-3; pmid: 11050440
    • (2000) Curr. Opin. Microbiol. , vol.3 , pp. 445
    • Rappuoli, R.1
  • 25
    • 33746593691 scopus 로고    scopus 로고
    • A universal vaccine for serogroup B meningococcus
    • doi: 10.1073/pnas.0603940103; pmid: 16825336
    • M. M. Giuliani et al., A universal vaccine for serogroup B meningococcus. Proc. Natl. Acad. Sci. U.S.A. 103, 10834 (2006). doi: 10.1073/pnas.0603940103; pmid: 16825336
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 10834
    • Giuliani, M.M.1
  • 26
    • 77958454595 scopus 로고    scopus 로고
    • Reverse vaccinology: Developing vaccines in the era of genomics
    • doi: 10.1016/j.immuni.2010.09.017; pmid: 21029963
    • A. Sette, R. Rappuoli, Reverse vaccinology: Developing vaccines in the era of genomics. Immunity 33, 530 (2010). doi: 10.1016/j.immuni.2010.09.017; pmid: 21029963
    • (2010) Immunity , vol.33 , pp. 530
    • Sette, A.1    Rappuoli, R.2
  • 27
    • 38749103554 scopus 로고    scopus 로고
    • Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
    • doi: 10.1084/jem.20071168; pmid: 18166586
    • C. Giefing et al ., Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies. J. Exp. Med. 205, 117 (2008). doi: 10.1084/jem.20071168; pmid: 18166586
    • (2008) J. Exp. Med. , vol.205 , pp. 117
    • Giefing, C.1
  • 28
    • 32344453260 scopus 로고    scopus 로고
    • Characterization and identification of vaccine candidate proteins through analysis of the group A streptococcus surface proteome
    • doi: 10.1038/nbt1179; pmid: 16415855
    • M. J. Rodríguez-Ortega et al., Characterization and identification of vaccine candidate proteins through analysis of the group A streptococcus surface proteome. Nat. Biotechnol. 24, 191 (2006). doi: 10.1038/nbt1179; pmid: 16415855
    • (2006) Nat. Biotechnol. , vol.24 , pp. 191
    • Rodríguez-Ortega, M.J.1
  • 29
    • 84878360585 scopus 로고    scopus 로고
    • S. A. Plotkin, W. Orenstein, P. A. Offit, Eds. W.B. Saunders, London
    • R. S. Daum, in Vaccines: Sixth Edition, S. A. Plotkin, W. Orenstein, P. A. Offit, Eds. (W.B. Saunders, London, 2013), pp. 1161-1168.
    • (2013) Vaccines: Sixth Edition , pp. 1161-1168
    • Daum, R.S.1
  • 30
    • 0036719574 scopus 로고    scopus 로고
    • Antibodies, viruses and vaccines
    • doi: 10.1038/nri891; pmid: 12209139
    • D. R. Burton, Antibodies, viruses and vaccines. Nat. Rev. Immunol. 2, 706 (2002). doi: 10.1038/nri891; pmid: 12209139
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 706
    • Burton, D.R.1
  • 31
    • 70349887757 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
    • Protocol G Principal Investigators, doi: 10.1126/science.1178746; pmid: 19729618
    • L. M. Walker et al.; Protocol G Principal Investigators, Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326, 285 (2009). doi: 10.1126/science.1178746; pmid: 19729618
    • (2009) Science , vol.326 , pp. 285
    • Walker, L.M.1
  • 32
    • 84866495323 scopus 로고    scopus 로고
    • Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
    • doi: 10.1016/j.immuni.2012.08.012; pmid: 22999947
    • P. D. Kwong, J. R. Mascola, Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies. Immunity 37, 412 (2012). doi: 10.1016/j.immuni.2012.08.012; pmid: 22999947
    • (2012) Immunity , vol.37 , pp. 412
    • Kwong, P.D.1    Mascola, J.R.2
  • 33
    • 84863774072 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
    • doi: 10.1126/science.1225416; pmid: 22798606
    • D. R. Burton, P. Poignard, R. L. Stanfield, I. A. Wilson, Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 337, 183 (2012). doi: 10.1126/science.1225416; pmid: 22798606
    • (2012) Science , vol.337 , pp. 183
    • Burton, D.R.1    Poignard, P.2    Stanfield, R.L.3    Wilson, I.A.4
  • 34
    • 77954943648 scopus 로고    scopus 로고
    • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
    • doi: 10.1126/science.1192819; pmid: 20616231
    • T. Zhou et al., Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 329, 811 (2010). doi: 10.1126/science.1192819; pmid: 20616231
    • (2010) Science , vol.329 , pp. 811
    • Zhou, T.1
  • 35
    • 80052925616 scopus 로고    scopus 로고
    • Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
    • doi: 10.1126/science.1207227; pmid: 21764753
    • J. F. Scheid et al., Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 333, 1633 (2011). doi: 10.1126/science.1207227; pmid: 21764753
    • (2011) Science , vol.333 , pp. 1633
    • Scheid, J.F.1
  • 36
    • 38049083122 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
    • doi: 10.1038/nm1698; pmid: 18064037
    • M. Law et al., Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nat. Med. 14, 25 (2008). doi: 10.1038/nm1698; pmid: 18064037
    • (2008) Nat. Med. , vol.14 , pp. 25
    • Law, M.1
  • 37
    • 80051635697 scopus 로고    scopus 로고
    • A highly conserved neutralizing epitope on group 2 influenza A viruses
    • doi: 10.1126/science.1204839; pmid: 21737702
    • D. C. Ekiert et al., A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 333, 843 (2011). doi: 10.1126/science.1204839; pmid: 21737702
    • (2011) Science , vol.333 , pp. 843
    • Ekiert, D.C.1
  • 38
    • 84891559198 scopus 로고    scopus 로고
    • Epitope-focused vaccines
    • W. Schief, Epitope-focused vaccines. Retrovirology 9 Suppl. 2, S03.04 (2012).
    • (2012) Retrovirology , vol.9 , Issue.SUPPL. 2
    • Schief, W.1
  • 39
    • 48449084590 scopus 로고    scopus 로고
    • Immune epitope database analysis resource (IEDB-AR)
    • doi: 10.1093/nar/gkn254; pmid: 18515843
    • Q. Zhang et al., Immune epitope database analysis resource (IEDB-AR). Nucleic Acids Res. 36, (Web Server), W513 (2008). doi: 10.1093/nar/gkn254; pmid: 18515843
    • (2008) Nucleic Acids Res. , vol.36 , Issue.WEB SERVER
    • Zhang, Q.1
  • 40
    • 20544465572 scopus 로고    scopus 로고
    • MHC multimer technology: Current status and future prospects
    • doi: 10.1016/j.coi.2005.06.008; pmid: 15967654
    • A. H. Bakker, T. N. Schumacher, MHC multimer technology: Current status and future prospects. Curr. Opin. Immunol. 17, 428 (2005). doi: 10.1016/j.coi.2005.06.008; pmid: 15967654
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 428
    • Bakker, A.H.1    Schumacher, T.N.2
  • 41
    • 0042191632 scopus 로고    scopus 로고
    • Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data
    • doi: 10.1073/pnas.1633254100; pmid: 12886016
    • D. L. Doolan et al., Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proc. Natl. Acad. Sci. U.S.A. 100, 9952 (2003). doi: 10.1073/pnas.1633254100; pmid: 12886016
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 9952
    • Doolan, D.L.1
  • 42
    • 14844318615 scopus 로고    scopus 로고
    • Analyzing Mycobacterium tuberculosis proteomes for candidate vaccine epitopes
    • doi: 10.1016/j.tube.2004.09.005; pmid: 15687033
    • J. McMurry et al., Analyzing Mycobacterium tuberculosis proteomes for candidate vaccine epitopes. Tuberculosis (Edinb.) 85, 95 (2005). doi: 10.1016/j.tube.2004.09.005; pmid: 15687033
    • (2005) Tuberculosis (Edinb.) , vol.85 , pp. 95
    • McMurry, J.1
  • 43
    • 77954097759 scopus 로고    scopus 로고
    • Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques
    • doi: 10.1002/eji.201040344; pmid: 20468055
    • M. Rosario et al., Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques. Eur. J. Immunol. 40, 1973 (2010). doi: 10.1002/eji.201040344; pmid: 20468055
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1973
    • Rosario, M.1
  • 44
    • 33846111016 scopus 로고    scopus 로고
    • Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants
    • doi: 10.1038/nm1461; pmid: 17187074
    • W. Fischer et al., Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nat. Med. 13, 100 (2007). doi: 10.1038/nm1461; pmid: 17187074
    • (2007) Nat. Med. , vol.13 , pp. 100
    • Fischer, W.1
  • 45
    • 33746132748 scopus 로고    scopus 로고
    • A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus
    • doi: 10.1038/nbt1215; pmid: 16767078
    • M. Moutaftsi et al., A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus. Nat. Biotechnol. 24, 817 (2006). doi: 10.1038/nbt1215; pmid: 16767078
    • (2006) Nat. Biotechnol. , vol.24 , pp. 817
    • Moutaftsi, M.1
  • 46
    • 34249813713 scopus 로고    scopus 로고
    • Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses
    • pmid: 17513729
    • M. Moutaftsi et al., Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. J. Immunol. 178, 6814 (2007). pmid: 17513729
    • (2007) J. Immunol. , vol.178 , pp. 6814
    • Moutaftsi, M.1
  • 47
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • doi: 10.1038/nature07469; pmid: 18997770
    • J. Liu et al., Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457, 87 (2009). doi: 10.1038/nature07469; pmid: 18997770
    • (2009) Nature , vol.457 , pp. 87
    • Liu, J.1
  • 48
    • 84868348755 scopus 로고    scopus 로고
    • Vaccine-induced CD8+ T cells control AIDS virus replication
    • doi: 10.1038/nature11443; pmid: 23023123
    • P. A. Mudd et al., Vaccine-induced CD8+ T cells control AIDS virus replication. Nature 491, 129 (2012). doi: 10.1038/nature11443; pmid: 23023123
    • (2012) Nature , vol.491 , pp. 129
    • Mudd, P.A.1
  • 49
    • 84870602529 scopus 로고    scopus 로고
    • ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans
    • doi: 10.1038/mt.2012.223; pmid: 23089736
    • S. H. Sheehy et al., ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans. Mol. Ther. 20, 2355 (2012). doi: 10.1038/mt.2012.223; pmid: 23089736
    • (2012) Mol. Ther. , vol.20 , pp. 2355
    • Sheehy, S.H.1
  • 50
    • 84875382846 scopus 로고    scopus 로고
    • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: A randomised, placebo-controlled phase 2b trial
    • the MVA85A 020 Trial Study Team, doi: 10.1016/S0140-6736(13)60177-4; pmid: 23391465
    • M. D. Tameris et al.; the MVA85A 020 Trial Study Team, Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: A randomised, placebo-controlled phase 2b trial. Lancet 381, 1021 (2013). doi: 10.1016/S0140-6736(13)60177-4; pmid: 23391465
    • (2013) Lancet , vol.381 , pp. 1021
    • Tameris, M.D.1
  • 51
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: Putting innate immunity to work
    • doi: 10.1016/j.immuni.2010.10.002; pmid: 21029960
    • R. L. Coffman, A. Sher, R. A. Seder, Vaccine adjuvants: Putting innate immunity to work. Immunity 33, 492 (2010). doi: 10.1016/j.immuni.2010.10.002; pmid: 21029960
    • (2010) Immunity , vol.33 , pp. 492
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 52
    • 61849170035 scopus 로고    scopus 로고
    • TLRs and innate immunity
    • doi: 10.1182/blood-2008-07-019307; pmid: 18757776
    • B. A. Beutler, TLRs and innate immunity. Blood 113, 1399 (2009). doi: 10.1182/blood-2008-07-019307; pmid: 18757776
    • (2009) Blood , vol.113 , pp. 1399
    • Beutler, B.A.1
  • 53
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • doi: 10.1038/ni1112; pmid: 15454922
    • A. Iwasaki, R. Medzhitov, Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987 (2004). doi: 10.1038/ni1112; pmid: 15454922
    • (2004) Nat. Immunol. , vol.5 , pp. 987
    • Iwasaki, A.1    Medzhitov, R.2
  • 54
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • doi: 10.1016/j.cell.2010.01.022; pmid: 20303872
    • O. Takeuchi, S. Akira, Pattern recognition receptors and inflammation. Cell 140, 805 (2010). doi: 10.1016/j.cell.2010.01.022; pmid: 20303872
    • (2010) Cell , vol.140 , pp. 805
    • Takeuchi, O.1    Akira, S.2
  • 55
    • 33845224163 scopus 로고    scopus 로고
    • Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity
    • doi: 10.1016/j.vaccine.2006.08.013; pmid: 16968658
    • J. W. Huleatt et al., Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine 25, 763 (2007). doi: 10.1016/j.vaccine.2006.08.013; pmid: 16968658
    • (2007) Vaccine , vol.25 , pp. 763
    • Huleatt, J.W.1
  • 56
    • 0343953087 scopus 로고    scopus 로고
    • Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity
    • doi: 10.1067/mai.2000.107927; pmid: 10887315
    • H. Tighe et al., Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity. J. Allergy Clin. Immunol. 106, 124 (2000). doi: 10.1067/mai.2000.107927; pmid: 10887315
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 124
    • Tighe, H.1
  • 57
    • 27244443079 scopus 로고    scopus 로고
    • HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates
    • doi: 10.1073/pnas.0507484102; pmid: 16219698
    • U. Wille-Reece et al., HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proc. Natl. Acad. Sci. U.S.A. 102, 15190 (2005). doi: 10.1073/pnas.0507484102; pmid: 16219698
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 15190
    • Wille-Reece, U.1
  • 58
    • 42549152118 scopus 로고    scopus 로고
    • CPG 7909 adjuvant plus hepatitis B virus vaccination in HIV-infected adults achieves long-term seroprotection for up to 5 years
    • doi: 10.1086/533467; pmid: 18444872
    • C. L. Cooper, J. B. Angel, I. Seguin, H. L. Davis, D. W. Cameron, CPG 7909 adjuvant plus hepatitis B virus vaccination in HIV-infected adults achieves long-term seroprotection for up to 5 years. Clin. Infect. Dis. 46, 1310 (2008). doi: 10.1086/533467; pmid: 18444872
    • (2008) Clin. Infect. Dis. , vol.46 , pp. 1310
    • Cooper, C.L.1    Angel, J.B.2    Seguin, I.3    Davis, H.L.4    Cameron, D.W.5
  • 59
    • 77958452906 scopus 로고    scopus 로고
    • Vaccination strategies to promote mucosal antibody responses
    • doi: 10.1016/j.immuni.2010.09.013; pmid: 21029959
    • K. Chen, A. Cerutti, Vaccination strategies to promote mucosal antibody responses. Immunity 33, 479 (2010). doi: 10.1016/j.immuni.2010.09.013; pmid: 21029959
    • (2010) Immunity , vol.33 , pp. 479
    • Chen, K.1    Cerutti, A.2
  • 60
    • 77958469466 scopus 로고    scopus 로고
    • Immunologic basis of vaccine vectors
    • doi: 10.1016/j.immuni.2010.10.004; pmid: 21029961
    • M. A. Liu, Immunologic basis of vaccine vectors. Immunity 33, 504 (2010). doi: 10.1016/j.immuni.2010.10.004; pmid: 21029961
    • (2010) Immunity , vol.33 , pp. 504
    • Liu, M.A.1
  • 61
    • 50449109985 scopus 로고    scopus 로고
    • Replicating viral vectors as HIV vaccines: Summary report from IAVI sponsored satellite symposium, International AIDS Society Conference, July 22, 2007
    • doi: 10.1016/j.biologicals.2008.04.004; pmid: 18555698
    • W. C. Koff et al., Replicating viral vectors as HIV vaccines: Summary report from IAVI sponsored satellite symposium, International AIDS Society Conference, July 22, 2007. Biologicals 36, 277 (2008). doi: 10.1016/j. biologicals.2008.04.004; pmid: 18555698
    • (2008) Biologicals , vol.36 , pp. 277
    • Koff, W.C.1
  • 62
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • doi: 10.1038/nm.1935; pmid: 19219024
    • S. G. Hansen et al., Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat. Med. 15, 293 (2009). doi: 10.1038/nm.1935; pmid: 19219024
    • (2009) Nat. Med. , vol.15 , pp. 293
    • Hansen, S.G.1
  • 63
    • 77958454596 scopus 로고    scopus 로고
    • Designing vaccines based on biology of human dendritic cell subsets
    • doi: 10.1016/j.immuni.2010.10.007; pmid: 21029958
    • K. Palucka, J. Banchereau, I. Mellman, Designing vaccines based on biology of human dendritic cell subsets. Immunity 33, 464 (2010). doi: 10.1016/j.immuni.2010.10.007; pmid: 21029958
    • (2010) Immunity , vol.33 , pp. 464
    • Palucka, K.1    Banchereau, J.2    Mellman, I.3
  • 64
    • 79957947384 scopus 로고    scopus 로고
    • Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine
    • doi:10.1093/infdis/jir199; pmid: 21628671
    • L. Lai et al., Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine. J. Infect. Dis. 204, 164 (2011). doi:10.1093/infdis/jir199; pmid: 21628671
    • (2011) J. Infect. Dis. , vol.204 , pp. 164
    • Lai, L.1
  • 65
    • 68249083949 scopus 로고    scopus 로고
    • Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity
    • doi: 10.1038/mt.2009.95; pmid: 19401673
    • J. E. Boudreau et al., Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity. Mol. Ther. 17, 1465 (2009). doi: 10.1038/mt.2009.95; pmid: 19401673
    • (2009) Mol. Ther. , vol.17 , pp. 1465
    • Boudreau, J.E.1
  • 66
    • 77958471315 scopus 로고    scopus 로고
    • Systems vaccinology
    • doi: 10.1016/j.immuni.2010.10.006; pmid: 21029962
    • B. Pulendran, S. Li, H. I. Nakaya, Systems vaccinology. Immunity 33, 516 (2010). doi: 10.1016/j.immuni.2010.10.006; pmid: 21029962
    • (2010) Immunity , vol.33 , pp. 516
    • Pulendran, B.1    Li, S.2    Nakaya, H.I.3
  • 67
    • 77949773550 scopus 로고    scopus 로고
    • Towards genome-scale signalling network reconstructions
    • doi: 10.1038/nrg2750; pmid: 20177425
    • D. R. Hyduke, B. O. Palsson, Towards genome-scale signalling network reconstructions. Nat. Rev. Genet. 11, 297 (2010). doi: 10.1038/nrg2750; pmid: 20177425
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 297
    • Hyduke, D.R.1    Palsson, B.O.2
  • 68
    • 57849085182 scopus 로고    scopus 로고
    • Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
    • doi: 10.1038/ni.1688; pmid: 19029902
    • T. D. Querec et al., Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 10, 116 (2009). doi: 10.1038/ni.1688; pmid: 19029902
    • (2009) Nat. Immunol. , vol.10 , pp. 116
    • Querec, T.D.1
  • 69
    • 80052942203 scopus 로고    scopus 로고
    • Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
    • NISC Comparative Sequencing Program, doi: 10.1126/science.1207532; pmid: 21835983
    • X. Wu et al ; NISC Comparative Sequencing Program, Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 333, 1593 (2011). doi: 10.1126/science.1207532; pmid: 21835983
    • (2011) Science , vol.333 , pp. 1593
    • Wu, X.1
  • 70
    • 77958479678 scopus 로고    scopus 로고
    • Vaccines and the future of human immunology
    • doi: 10.1016/j.immuni.2010.09.014; pmid: 21029956
    • R. N. Germain, Vaccines and the future of human immunology. Immunity 33, 441 (2010). doi: 10.1016/j.immuni.2010.09.014; pmid: 21029956
    • (2010) Immunity , vol.33 , pp. 441
    • Germain, R.N.1
  • 71
    • 68849103521 scopus 로고    scopus 로고
    • Mass cytometry: Technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry
    • doi: 10.1021/ac901049w; pmid: 19601617
    • D. R. Bandura et al., Mass cytometry: Technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal. Chem. 81, 6813 (2009). doi: 10.1021/ac901049w; pmid: 19601617
    • (2009) Anal. Chem. , vol.81 , pp. 6813
    • Bandura, D.R.1
  • 72
    • 55449095864 scopus 로고    scopus 로고
    • A chromatic explosion: The development and future of multiparameter flow cytometry
    • doi: 10.1111/j.1365-2567.2008.02989.x; pmid: 19137647
    • P. K. Chattopadhyay, C. M. Hogerkorp, M. Roederer, A chromatic explosion: The development and future of multiparameter flow cytometry. Immunology 125, 441 (2008). doi: 10.1111/j.1365-2567.2008.02989.x; pmid: 19137647
    • (2008) Immunology , vol.125 , pp. 441
    • Chattopadhyay, P.K.1    Hogerkorp, C.M.2    Roederer, M.3
  • 74
    • 57449096122 scopus 로고    scopus 로고
    • A prescription for human immunology
    • doi: 10.1016/j.immuni.2008.12.003; pmid: 19100694
    • M. M. Davis, A prescription for human immunology. Immunity 29, 835 (2008). doi: 10.1016/j.immuni.2008.12.003; pmid: 19100694
    • (2008) Immunity , vol.29 , pp. 835
    • Davis, M.M.1
  • 75
    • 84874457770 scopus 로고    scopus 로고
    • Genomic responses in mouse models poorly mimic human inflammatory diseases
    • Inflammation and Host Response to Injury, Large Scale Collaborative Research Program, doi: 10.1073/pnas.1222878110; pmid: 23401516
    • J. Seok et al.; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program, Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc. Natl. Acad. Sci. U.S.A. 110, 3507 (2013). doi: 10.1073/pnas.1222878110; pmid: 23401516
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 3507
    • Seok, J.1
  • 76
    • 27744473566 scopus 로고    scopus 로고
    • Lost in translation: Barriers to implementing clinical immunotherapeutics for autoimmunity
    • doi: 10.1084/jem.20051224; pmid: 16275758
    • M. G. von Herrath, G. T. Nepom, Lost in translation: Barriers to implementing clinical immunotherapeutics for autoimmunity. J. Exp. Med. 202, 1159 (2005). doi: 10.1084/jem.20051224; pmid: 16275758
    • (2005) J. Exp. Med. , vol.202 , pp. 1159
    • Von Herrath, M.G.1    Nepom, G.T.2
  • 77
    • 70349202192 scopus 로고    scopus 로고
    • CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans
    • doi: 10.1172/JCI38294; pmid: 19726873
    • J. D. Campbell et al ., CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans. J. Clin. Invest. 119, 2564 (2009). doi: 10.1172/JCI38294; pmid: 19726873
    • (2009) J. Clin. Invest. , vol.119 , pp. 2564
    • Campbell, J.D.1
  • 78
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • pmid: 14978070
    • J. Mestas, C. C. Hughes, Of mice and not men: Differences between mouse and human immunology. J. Immunol. 172, 2731 (2004). pmid: 14978070
    • (2004) J. Immunol. , vol.172 , pp. 2731
    • Mestas, J.1    Hughes, C.C.2
  • 79
    • 35548956882 scopus 로고    scopus 로고
    • Immunology in natura: Clinical, epidemiological and evolutionary genetics of infectious diseases
    • doi: 10.1038/ni1535; pmid: 17952041
    • L. Quintana-Murci, A. Alcaïs, L. Abel, J. L. Casanova, Immunology in natura: Clinical, epidemiological and evolutionary genetics of infectious diseases. Nat. Immunol. 8, 1165 (2007). doi: 10.1038/ni1535; pmid: 17952041
    • (2007) Nat. Immunol. , vol.8 , pp. 1165
    • Quintana-Murci, L.1    Alcaïs, A.2    Abel, L.3    Casanova, J.L.4
  • 80
    • 51349093240 scopus 로고    scopus 로고
    • Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells
    • doi: 10.1016/j.immuni.2008.07.013; pmid: 18789730
    • E. Klechevsky et al., Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity 29, 497 (2008). doi: 10.1016/j.immuni.2008.07.013; pmid: 18789730
    • (2008) Immunity , vol.29 , pp. 497
    • Klechevsky, E.1
  • 81
    • 84860876434 scopus 로고    scopus 로고
    • Current advances in humanized mouse models
    • doi: 10.1038/cmi.2012.2; pmid: 22327211
    • R. Ito, T. Takahashi, I. Katano, M. Ito, Current advances in humanized mouse models. Cell. Mol. Immunol. 9, 208 (2012). doi: 10.1038/cmi.2012.2; pmid: 22327211
    • (2012) Cell. Mol. Immunol. , vol.9 , pp. 208
    • Ito, R.1    Takahashi, T.2    Katano, I.3    Ito, M.4
  • 82
    • 15244346957 scopus 로고    scopus 로고
    • Retrovirus restriction by TRIM5alpha variants from Old World and New World primates
    • doi: 10.1128/JVI.79.7.3930-3937.2005; pmid: 15767395
    • B. Song et al., Retrovirus restriction by TRIM5alpha variants from Old World and New World primates. J. Virol. 79, 3930 (2005). doi: 10.1128/JVI.79.7.3930-3937.2005; pmid: 15767395
    • (2005) J. Virol. , vol.79 , pp. 3930
    • Song, B.1
  • 83
    • 80053462850 scopus 로고    scopus 로고
    • Metagenomics and personalized medicine
    • doi: 10.1016/j.cell.2011.09.009; pmid: 21962506
    • H. W. Virgin, J. A. Todd, Metagenomics and personalized medicine. Cell 147, 44 (2011). doi: 10.1016/j.cell.2011.09.009; pmid: 21962506
    • (2011) Cell , vol.147 , pp. 44
    • Virgin, H.W.1    Todd, J.A.2
  • 84
    • 67649660551 scopus 로고    scopus 로고
    • Redefining chronic viral infection
    • doi: 10.1016/j.cell.2009.06.036; pmid: 19596234
    • H. W. Virgin, E. J. Wherry, R. Ahmed, Redefining chronic viral infection. Cell 138, 30 (2009). doi: 10.1016/j.cell.2009.06.036; pmid: 19596234
    • (2009) Cell , vol.138 , pp. 30
    • Virgin, H.W.1    Wherry, E.J.2    Ahmed, R.3
  • 85
    • 44949100369 scopus 로고    scopus 로고
    • Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
    • doi: 10.1038/nm.f.1759; pmid: 18535579
    • D. I. Watkins, D. R. Burton, E. G. Kallas, J. P. Moore, W. C. Koff, Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nat. Med. 14, 617 (2008). doi: 10.1038/nm.f.1759; pmid: 18535579
    • (2008) Nat. Med. , vol.14 , pp. 617
    • Watkins, D.I.1    Burton, D.R.2    Kallas, E.G.3    Moore, J.P.4    Koff, W.C.5
  • 86
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Step Study Protocol Team, doi: 10.1016/S0140-6736(08)61591-3; pmid: 19012954
    • S. P. Buchbinder et al.; Step Study Protocol Team, Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372, 1881 (2008). doi: 10.1016/S0140-6736(08)61591-3; pmid: 19012954
    • (2008) Lancet , vol.372 , pp. 1881
    • Buchbinder, S.P.1
  • 87
    • 0029927993 scopus 로고    scopus 로고
    • Vaccine R&D success rates and development times
    • doi: 10.1038/nbt0596-591; pmid: 9630948
    • M. M. Struck, Vaccine R&D success rates and development times. Nat. Biotechnol. 14, 591 (1996). doi: 10.1038/nbt0596-591; pmid: 9630948
    • (1996) Nat. Biotechnol. , vol.14 , pp. 591
    • Struck, M.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.