Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: A comprehensive study using the most potent and broadly neutralizing monoclonal antibodies

Journal of Virology

Volumn 88, Issue 23, 2014, Pages 13910-13917

  Bouvin Pley, M ^a   Morgand, M ^a   Meyer, L ^b,c   Goujard, C ^b,c   Moreau, A ^a   Mouquet, H ^d   Nussenzweig, M ^e   Pace, C ^e,l   Ho, D ^e   Bjorkman, P J ^f   Baty, D ^g   Chames, P ^g   Pancera, M ^h   Kwong, P D ^h   Poignard, P ^i,j   Barin, F ^a,k   Braibant, M ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c BICÊTRE HOSPITAL   (France)

^d INSTITUT PASTEUR   (France)

^e ROCKEFELLER UNIVERSITY   (United States)

^f CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^g AIX MARSEILLE UNIVERSITY   (France)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

ⁱ SCRIPPS RESEARCH INSTITUTE   (United States)

^j International AIDS Vaccine Initiative Neutralizing Antibody Center   (United States)

^k CHU BRETONNEAU   (France)

^l GILEAD SCIENCES   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; IBALIZUMAB; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; GP120 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; GP41 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

ANTIBODY SPECIFICITY; ARTICLE; BINDING SITE; CLADISTICS; CLINICAL ARTICLE; CONTROLLED STUDY; ENVELOPE GENE; GENETIC VARIABILITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMORAL IMMUNITY; IC50; MALE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; VIRUS NEUTRALIZATION; VIRUS RESISTANCE; VIRUS TRANSMISSION; ANIMAL; EPIDEMIC; GENETIC DRIFT; GENETICS; HIV INFECTIONS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOUSE; SERODIAGNOSIS; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; EPIDEMICS; GENETIC DRIFT; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV INFECTIONS; HIV-1; HUMANS; MALE; MICE; NEUTRALIZATION TESTS;

EID: 84911459185     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02083-14     Document Type: Article

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