Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression

Science Signaling

Volumn 10, Issue 472, 2017, Pages

  Andrieu, Guillaume ^a,b,c   Ledoux, Adeline ^a,b,c   Branka, Sophie ^a,b,c   Bocquet, Magalie ^a,b,c   Gilhodes, Julia ^d   Walzer, Thierry ^e   Kasahara, Kousuke ^f   Inagaki, Masaki ^f   Sabbadini, Roger A ^g   Cuvillier, Olivier ^a,b,c   Hatzoglou, Anastassia ^a,b,c  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c Chemical Biology of Cancer Team   (France)

^d INSTITUT CLAUDIUS REGAUD   (France)

^e CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^f AICHI CANCER CENTER HOSPITAL   (Japan)

^g Lpath Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 (3 OCTYLPHENYLCARBAMOYL)ETHYL PHOSPHATE; 4 (2,6 DICHLORO 4 PYRIDINYL) 1 (1,3 DIMETHYL 4 ISOPROPYL 1H PYRAZOLO[3,4 B]PYRIDIN 6 YL)SEMICARBAZIDE; CYCLIN B1; DOXYCYCLINE; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOCODAZOLE; PHOSPHATIDYLINOSITOL 3 KINASE; POLO LIKE KINASE 1; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; CELL CYCLE PROTEIN; LYSOPHOSPHOLIPID; ONCOPROTEIN; PHOSPHOTRANSFERASE; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANAPHASE; ARTICLE; CHROMOSOME CONDENSATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HELA CELL LINE; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; METAPHASE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS INDEX; MITOSIS INHIBITION; MITOSIS RATE; PHENOTYPE; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PROCEDURES; RNA INTERFERENCE; TIME LAPSE IMAGING; TUMOR CELL LINE;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; CHROMOSOME SEGREGATION; HELA CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MITOSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, LYSOSPHINGOLIPID; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPHINGOSINE; TIME-LAPSE IMAGING;

EID: 85017547406     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aah4007     Document Type: Article

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