Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 cells by a multiplex CRISPR/Cas9 strategy results in glycoproteins without plant-specific glycans

Frontiers in Plant Science

Volumn 8, Issue , 2017, Pages

  Mercx, Sébastien ^a   Smargiasso, Nicolas ^b   Chaumont, François ^a   De Pauw, Edwin ^b   Boutry, Marc ^a   Navarre, Catherine ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Antibody; Gene editing; Glyco engineering; Glycoproteins; Humanized N glycosylation; Molecular farming; Plant specific glycans; Suspension cells

Indexed keywords

EID: 85017326066     PISSN: None     EISSN: 1664462X     Source Type: Journal    
DOI: 10.3389/fpls.2017.00403     Document Type: Article

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