Multiplexed, targeted gene editing in Nicotiana benthamiana for glyco-engineering and monoclonal antibody production

Plant Biotechnology Journal

Volumn 14, Issue 2, 2016, Pages 533-542

  Li, Jin ^a   Stoddard, Thomas J ^a   Demorest, Zachary L ^a   Lavoie, Pierre Olivier ^b   Luo, Song ^a   Clasen, Benjamin M ^a   Cedrone, Frederic ^a   Ray, Erin E ^a   Coffman, Andrew P ^a   Daulhac, Aurelie ^a   Yabandith, Ann ^a   Retterath, Adam J ^a   Mathis, Luc ^a   Voytas, Daniel F ^a   D'Aoust, Marc André ^b   Zhang, Feng ^a  

^a Arvid Wallgrens Backe 20   (France)

^b Medicago Inc   (Canada)

Author keywords

Gene editing; Glyco engineering; Plant derived pharmaceuticals; Transcription activator like effector nucleases

Indexed keywords

FUCOSE; MONOCLONAL ANTIBODY; PLANT PROTEIN; POLYSACCHARIDE; RITUXIMAB; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; XYLOSE;

BIOSYNTHESIS; CHEMISTRY; GENE EDITING; GENETIC ENGINEERING; GENETIC TRANSFORMATION; GENETICS; GLYCOSYLATION; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PROCEDURES; PROTOPLAST; TOBACCO; TRANSGENIC PLANT;

ANTIBODIES, MONOCLONAL; BASE SEQUENCE; FUCOSE; GENE EDITING; GENETIC ENGINEERING; GLYCOSYLATION; MUTATION; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; POLYSACCHARIDES; PROTOPLASTS; RITUXIMAB; TOBACCO; TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES; TRANSFORMATION, GENETIC; XYLOSE;

EID: 84930028449     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12403     Document Type: Article

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