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Volumn 312, Issue 4, 2017, Pages C398-C406

Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells

Author keywords

Calcium imaging; Connexin; Endothelial cell; Mitochondria; Reactive oxygen species

Indexed keywords

ATP SYNTHASE SUBUNIT 5 ALPHA; CALCIUM; CALMODULIN; CONNEXIN 40; CYCLOPIAZONIC ACID; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; GAP JUNCTION PROTEIN; MITOCHONDRIAL PROTEIN;

EID: 85017301865     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00283.2016     Document Type: Article
Times cited : (23)

References (65)
  • 1
    • 77956223101 scopus 로고    scopus 로고
    • Calcium and mitochondrial reactive oxygen species generation: How to read the facts
    • Adam-Vizi V, Starkov AA. Calcium and mitochondrial reactive oxygen species generation: how to read the facts. J Alzheimers Dis 20, Suppl 2: S413-S426, 2010. doi:10.3233/JAD-2010-100465.
    • (2010) J Alzheimers Dis , vol.20 , pp. S413-S426
    • Adam-Vizi, V.1    Starkov, A.A.2
  • 2
    • 78249264775 scopus 로고    scopus 로고
    • Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta
    • Alonso F, Boittin FX, Bény JL, Haefliger JA. Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta. Am J Physiol Heart Circ Physiol 299: H1365-H1373, 2010. doi:10.1152/ajpheart.00029.2010.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. H1365-H1373
    • Alonso, F.1    Boittin, F.X.2    Bény, J.L.3    Haefliger, J.A.4
  • 7
    • 58149099301 scopus 로고    scopus 로고
    • Connexins in vascular physiology and pathology
    • Brisset AC, Isakson BE, Kwak BR. Connexins in vascular physiology and pathology. Antioxid Redox Signal 11: 267-282, 2009. doi:10.1089/ ars.2008.2115.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 267-282
    • Brisset, A.C.1    Isakson, B.E.2    Kwak, B.R.3
  • 9
    • 0034975688 scopus 로고    scopus 로고
    • Connexin37, not Cx40 and Cx43, is induced in vascular smooth muscle cells during coronary arteriogenesis
    • Cai WJ, Koltai S, Kocsis E, Scholz D, Schaper W, Schaper J. Connexin37, not Cx40 and Cx43, is induced in vascular smooth muscle cells during coronary arteriogenesis. J Mol Cell Cardiol 33: 957-967, 2001. doi:10.1006/jmcc.2001.1360.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 957-967
    • Cai, W.J.1    Koltai, S.2    Kocsis, E.3    Scholz, D.4    Schaper, W.5    Schaper, J.6
  • 11
    • 84887580283 scopus 로고    scopus 로고
    • Coronary endothelial dysfunction and mitochondrial reactive oxygen species in type 2 diabetic mice
    • Cho YE, Basu A, Dai A, Heldak M, Makino A. Coronary endothelial dysfunction and mitochondrial reactive oxygen species in type 2 diabetic mice. Am J Physiol Cell Physiol 305: C1033-C1040, 2013. doi:10.1152/ ajpcell.00234.2013.
    • (2013) Am J Physiol Cell Physiol , vol.305 , pp. C1033-C1040
    • Cho, Y.E.1    Basu, A.2    Dai, A.3    Heldak, M.4    Makino, A.5
  • 13
    • 0034737654 scopus 로고    scopus 로고
    • Impaired conduction of vasodilation along arterioles in connexin40-deficient mice
    • de Wit C, Roos F, Bolz SS, Kirchhoff S, Krüger O, Willecke K, Pohl U. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ Res 86: 649-655, 2000. doi:10.1161/01.RES.86.6. 649.
    • (2000) Circ Res , vol.86 , pp. 649-655
    • De Wit, C.1    Roos, F.2    Bolz, S.S.3    Kirchhoff, S.4    Krüger, O.5    Willecke, K.6    Pohl, U.7
  • 15
    • 84995639334 scopus 로고    scopus 로고
    • Next-generation connexin and pannexin cell biology
    • Esseltine JL, Laird DW. Next-generation connexin and pannexin cell biology. Trends Cell Biol 26: 944-955, 2016. doi:10.1016/j.tcb.2016.06. 003.
    • (2016) Trends Cell Biol , vol.26 , pp. 944-955
    • Esseltine, J.L.1    Laird, D.W.2
  • 17
    • 84934990551 scopus 로고    scopus 로고
    • Cell communication across gap junctions: A historical perspective and current developments
    • Evans WH. Cell communication across gap junctions: a historical perspective and current developments. Biochem Soc Trans 43: 450-459, 2015. doi:10.1042/BST20150056.
    • (2015) Biochem Soc Trans , vol.43 , pp. 450-459
    • Evans, W.H.1
  • 19
    • 58149100084 scopus 로고    scopus 로고
    • Gap junctions in the control of vascular function
    • Figueroa XF, Duling BR. Gap junctions in the control of vascular function. Antioxid Redox Signal 11: 251-266, 2009. doi:10.1089/ars.2008. 2117.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 251-266
    • Figueroa, X.F.1    Duling, B.R.2
  • 20
    • 84879373237 scopus 로고    scopus 로고
    • The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus
    • Fowler SL, Akins M, Zhou H, Figeys D, Bennett SA. The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus. J Proteome Res 12: 2597-2610, 2013. doi:10.1021/ pr301166p.
    • (2013) J Proteome Res , vol.12 , pp. 2597-2610
    • Fowler, S.L.1    Akins, M.2    Zhou, H.3    Figeys, D.4    Bennett, S.A.5
  • 24
    • 1942470625 scopus 로고    scopus 로고
    • Contribution of connexins to the function of the vascular wall
    • Haefliger JA, Nicod P, Meda P. Contribution of connexins to the function of the vascular wall. Cardiovasc Res 62: 345-356, 2004. doi:10. 1016/j.cardiores.2003.11.015.
    • (2004) Cardiovasc Res , vol.62 , pp. 345-356
    • Haefliger, J.A.1    Nicod, P.2    Meda, P.3
  • 26
    • 0036016630 scopus 로고    scopus 로고
    • Heterogeneity in the distribution of vascular gap junctions and connexins: Implications for function
    • Hill CE, Rummery N, Hickey H, Sandow SL. Heterogeneity in the distribution of vascular gap junctions and connexins: implications for function. Clin Exp Pharmacol Physiol 29: 620-625, 2002. doi:10.1046/j. 1440-1681.2002.03699.x.
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 620-625
    • Hill, C.E.1    Rummery, N.2    Hickey, H.3    Sandow, S.L.4
  • 27
    • 0031824584 scopus 로고    scopus 로고
    • Restricted expression of the gap junctional protein connexin 43 in the arterial system of the rat
    • Hong T, Hill CE. Restricted expression of the gap junctional protein connexin 43 in the arterial system of the rat. J Anat 192: 583-593, 1998. doi:10.1046/j.1469-7580.1998.19240583.x.
    • (1998) J Anat , vol.192 , pp. 583-593
    • Hong, T.1    Hill, C.E.2
  • 28
    • 0025913049 scopus 로고
    • + channel in the mitochondrial inner membrane
    • + channel in the mitochondrial inner membrane. Nature 352: 244-247, 1991. doi:10.1038/ 352244a0.
    • (1991) Nature , vol.352 , pp. 244-247
    • Inoue, I.1    Nagase, H.2    Kishi, K.3    Higuti, T.4
  • 29
    • 33645735805 scopus 로고    scopus 로고
    • Connexin40 and connexin43 in mouse aortic endothelium: Evidence for coordinated regulation
    • Isakson BE, Damon DN, Day KH, Liao Y, Duling BR. Connexin40 and connexin43 in mouse aortic endothelium: evidence for coordinated regulation. Am J Physiol Heart Circ Physiol 290: H1199-H1205, 2006. doi:10.1152/ajpheart.00945.2005.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H1199-H1205
    • Isakson, B.E.1    Damon, D.N.2    Day, K.H.3    Liao, Y.4    Duling, B.R.5
  • 30
    • 84861582126 scopus 로고    scopus 로고
    • Connexin43 phosphorylation and cytoprotection in the heart
    • Jeyaraman MM, Srisakuldee W, Nickel BE, Kardami E. Connexin43 phosphorylation and cytoprotection in the heart. Biochim Biophys Acta 1818: 2009-2013, 2012. doi:10.1016/j.bbamem.2011.06.023.
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 2009-2013
    • Jeyaraman, M.M.1    Srisakuldee, W.2    Nickel, B.E.3    Kardami, E.4
  • 32
    • 68649095201 scopus 로고    scopus 로고
    • Mitochondrial calcium and the permeability transition in cell death
    • Lemasters JJ, Theruvath TP, Zhong Z, Nieminen AL. Mitochondrial calcium and the permeability transition in cell death. Biochim Biophys Acta 1787: 1395-1401, 2009. doi:10.1016/j.bbabio.2009.06.009.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1395-1401
    • Lemasters, J.J.1    Theruvath, T.P.2    Zhong, Z.3    Nieminen, A.L.4
  • 34
    • 84979948880 scopus 로고    scopus 로고
    • Isolation of mouse coronary endothelial cells
    • Luo S, Truong AH, Makino A. Isolation of mouse coronary endothelial cells. J Vis Exp 113: e53985, 2016. doi:10.3791/53985.
    • (2016) J Vis Exp , vol.113
    • Luo, S.1    Truong, A.H.2    Makino, A.3
  • 36
    • 52749094907 scopus 로고    scopus 로고
    • Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice
    • Makino A, Platoshyn O, Suarez J, Yuan JX, Dillmann WH. Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice. Am J Physiol Cell Physiol 295: C221-C230, 2008. doi:10.1152/ajpcell.00433.2007.
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. C221-C230
    • Makino, A.1    Platoshyn, O.2    Suarez, J.3    Yuan, J.X.4    Dillmann, W.H.5
  • 37
    • 77955509429 scopus 로고    scopus 로고
    • Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes
    • Makino A, Scott BT, Dillmann WH. Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. Diabetologia 53: 1783-1794, 2010. doi:10.1007/ s00125-010-1770-4.
    • (2010) Diabetologia , vol.53 , pp. 1783-1794
    • Makino, A.1    Scott, B.T.2    Dillmann, W.H.3
  • 38
    • 0037317019 scopus 로고    scopus 로고
    • The mitochondrial KATP channel and cardioprotection
    • McCully JD, Levitsky S. The mitochondrial KATP channel and cardioprotection. Ann Thorac Surg 75: S667-S673, 2003. doi:10.1016/S0003-4975(02)04689-1.
    • (2003) Ann Thorac Surg , vol.75 , pp. S667-S673
    • McCully, J.D.1    Levitsky, S.2
  • 40
    • 80051736986 scopus 로고    scopus 로고
    • Novel role of mitochondrial matrix metalloproteinase-2 in the development of diabetic retinopathy
    • Mohammad G, Kowluru RA. Novel role of mitochondrial matrix metalloproteinase-2 in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci 52: 3832-3841, 2011. doi:10.1167/iovs.10-6368.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3832-3841
    • Mohammad, G.1    Kowluru, R.A.2
  • 42
    • 1542343927 scopus 로고    scopus 로고
    • + channels and their role in cardioprotection
    • + channels and their role in cardioprotection. Circ Res 94: 420-432, 2004. doi:10.1161/01.RES. 0000117583.66950.43.
    • (2004) Circ Res , vol.94 , pp. 420-432
    • O’Rourke, B.1
  • 43
    • 33947388409 scopus 로고    scopus 로고
    • Mitochondrial ion channels
    • O’Rourke B. Mitochondrial ion channels. Annu Rev Physiol 69: 19-49, 2007. doi:10.1146/annurev.physiol.69.031905.163804.
    • (2007) Annu Rev Physiol , vol.69 , pp. 19-49
    • O’Rourke, B.1
  • 44
    • 63349107500 scopus 로고    scopus 로고
    • Connexin32 is expressed in vascular endothelial cells and participates in gap-junction intercellular communication
    • Okamoto T, Akiyama M, Takeda M, Gabazza EC, Hayashi T, Suzuki K. Connexin32 is expressed in vascular endothelial cells and participates in gap-junction intercellular communication. Biochem Biophys Res Commun 382: 264-268, 2009. doi:10.1016/j.bbrc.2009.02.148.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 264-268
    • Okamoto, T.1    Akiyama, M.2    Takeda, M.3    Gabazza, E.C.4    Hayashi, T.5    Suzuki, K.6
  • 45
    • 84908006671 scopus 로고    scopus 로고
    • Hemichannel composition and electrical synaptic transmission: Molecular diversity and its implications for electrical rectification
    • Palacios-Prado N, Huetteroth W, Pereda AE. Hemichannel composition and electrical synaptic transmission: molecular diversity and its implications for electrical rectification. Front Cell Neurosci 8: 324, 2014. doi:10.3389/fncel.2014.00324.
    • (2014) Front Cell Neurosci , vol.8 , pp. 324
    • Palacios-Prado, N.1    Huetteroth, W.2    Pereda, A.E.3
  • 47
    • 77955291571 scopus 로고    scopus 로고
    • Oxidative stress caused by mitochondrial calcium overload
    • Peng TI, Jou MJ. Oxidative stress caused by mitochondrial calcium overload. Ann NY Acad Sci 1201: 183-188, 2010. doi:10.1111/j.1749-6632.2010.05634.x.
    • (2010) Ann NY Acad Sci , vol.1201 , pp. 183-188
    • Peng, T.I.1    Jou, M.J.2
  • 50
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: Their regulation and functions
    • Saez JC, Berthoud VM, Branes MC, Martinez AD, Beyer EC. Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev 83: 1359-1400, 2003. doi:10.1152/physrev.00007.2003.
    • (2003) Physiol Rev , vol.83 , pp. 1359-1400
    • Saez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 51
    • 84988530975 scopus 로고    scopus 로고
    • Modulation of the matrix redox signaling by mitochondrial Ca(2.)
    • Santo-Domingo J, Wiederkehr A, De Marchi U. Modulation of the matrix redox signaling by mitochondrial Ca(2.). World J Biol Chem 6: 310-323, 2015. doi:10.4331/wjbc.v6.i4.310.
    • (2015) World J Biol Chem , vol.6 , pp. 310-323
    • Santo-Domingo, J.1    Wiederkehr, A.2    De Marchi, U.3
  • 53
    • 0033551036 scopus 로고    scopus 로고
    • 2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line
    • 2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line. Biochem Biophys Res Commun 257: 549-554, 1999. doi:10.1006/bbrc.1999.0496.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 549-554
    • Siemen, D.1    Loupatatzis, C.2    Borecky, J.3    Gulbins, E.4    Lang, F.5
  • 54
    • 0038010467 scopus 로고    scopus 로고
    • Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40
    • Simon AM, McWhorter AR. Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40. J Cell Sci 116: 2223-2236, 2003. doi:10. 1242/jcs.00429.
    • (2003) J Cell Sci , vol.116 , pp. 2223-2236
    • Simon, A.M.1    McWhorter, A.R.2
  • 55
    • 0345865173 scopus 로고    scopus 로고
    • Role of connexin37 and connexin40 in vascular development
    • Simon AM, McWhorter AR. Role of connexin37 and connexin40 in vascular development. Cell Commun Adhes 10: 379-385, 2003. doi:10. 1080/cac.10.4-6.379.385.
    • (2003) Cell Commun Adhes , vol.10 , pp. 379-385
    • Simon, A.M.1    McWhorter, A.R.2
  • 56
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Söhl G, Willecke K. Gap junctions and the connexin protein family. Cardiovasc Res 62: 228-232, 2004. doi:10.1016/j.cardiores.2003.11.013.
    • (2004) Cardiovasc Res , vol.62 , pp. 228-232
    • Söhl, G.1    Willecke, K.2
  • 58
    • 84904015361 scopus 로고    scopus 로고
    • The FGF-2-triggered protection of cardiac subsarcolemmal mitochondria from calcium overload is mitochondrial connexin 43-dependent
    • Srisakuldee W, Makazan Z, Nickel BE, Zhang F, Thliveris JA, Pasumarthi KB, Kardami E. The FGF-2-triggered protection of cardiac subsarcolemmal mitochondria from calcium overload is mitochondrial connexin 43-dependent. Cardiovasc Res 103: 72-80, 2014. doi:10.1093/ cvr/cvu066.
    • (2014) Cardiovasc Res , vol.103 , pp. 72-80
    • Srisakuldee, W.1    Makazan, Z.2    Nickel, B.E.3    Zhang, F.4    Thliveris, J.A.5    Pasumarthi, K.B.6    Kardami, E.7
  • 60
    • 84865014310 scopus 로고    scopus 로고
    • Connexin 43 interacts with Bax to regulate apoptosis of pancreatic cancer through a gap junctionindependent pathway
    • Sun Y, Zhao X, Yao Y, Qi X, Yuan Y, Hu Y. Connexin 43 interacts with Bax to regulate apoptosis of pancreatic cancer through a gap junctionindependent pathway. Int J Oncol 41: 941-948, 2012. doi:10.3892/ijo. 2012.1524.
    • (2012) Int J Oncol , vol.41 , pp. 941-948
    • Sun, Y.1    Zhao, X.2    Yao, Y.3    Qi, X.4    Yuan, Y.5    Hu, Y.6
  • 62
    • 84871875952 scopus 로고    scopus 로고
    • Downregulation of mitochondrial connexin 43 by high glucose triggers mitochondrial shape change and cytochrome C release in retinal endothelial cells
    • Trudeau K, Muto T, Roy S. Downregulation of mitochondrial connexin 43 by high glucose triggers mitochondrial shape change and cytochrome C release in retinal endothelial cells. Invest Ophthalmol Vis Sci 53: 6675-6681, 2012. doi:10.1167/iovs.12-9895.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 6675-6681
    • Trudeau, K.1    Muto, T.2    Roy, S.3
  • 63
    • 0030909330 scopus 로고    scopus 로고
    • Gap junction localization and connexin expression in cytochemically identified endothelial cells of arterial tissue
    • Yeh HI, Dupont E, Coppen S, Rothery S, Severs NJ. Gap junction localization and connexin expression in cytochemically identified endothelial cells of arterial tissue. J Histochem Cytochem 45: 539-550, 1997. doi:10.1177/002215549704500406.
    • (1997) J Histochem Cytochem , vol.45 , pp. 539-550
    • Yeh, H.I.1    Dupont, E.2    Coppen, S.3    Rothery, S.4    Severs, N.J.5
  • 64
    • 77950353205 scopus 로고    scopus 로고
    • 2+ bursts and endothelial nitric oxide synthase activation in ovine uterine artery endothelial cells through increased connexin 43 function
    • 2+ bursts and endothelial nitric oxide synthase activation in ovine uterine artery endothelial cells through increased connexin 43 function. Biol Reprod 82: 66-75, 2010. doi:10.1095/biolreprod.109.078253.
    • (2010) Biol Reprod , vol.82 , pp. 66-75
    • Yi, F.X.1    Boeldt, D.S.2    Gifford, S.M.3    Sullivan, J.A.4    Grummer, M.A.5    Magness, R.R.6    Bird, I.M.7
  • 65
    • 34250825264 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen speciesmediated signaling in endothelial cells
    • Zhang DX, Gutterman DD. Mitochondrial reactive oxygen speciesmediated signaling in endothelial cells. Am J Physiol Heart Circ Physiol 292: H2023-H2031, 2007. doi:10.1152/ajpheart.01283.2006.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H2023-H2031
    • Zhang, D.X.1    Gutterman, D.D.2


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