Mitochondrial small conductance sk2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction

Journal of Biological Chemistry

Volumn 288, Issue 15, 2013, Pages 10792-10804

  Dolga, Amalia M ^a   Netter, Michael F ^a   Perocchi, Fabiana ^b,c   Doti, Nunzianna ^a,d,e   Meissner, Lilja ^f   Tobaben, Svenja ^a   Grohm, Julia ^a   Zischka, Hans ^g   Plesnila, Nikolaus ^d,f   Decher, Niels ^a   Culmsee, Carsten ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^e CNR   (Italy)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^g INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM-ACTIVATED POTASSIUM; INHIBITORY PEPTIDES; INNER MITOCHONDRIAL MEMBRANES; INTERMEMBRANE SPACE; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSMEMBRANE POTENTIALS; PATCH CLAMP RECORDING;

BIOELECTRIC POTENTIALS; CELL DEATH; CELL MEMBRANES; ELECTROPHYSIOLOGY; PROTEINS;

MITOCHONDRIA;

GLUTAMIC ACID; MITOCHONDRIAL PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PEPTIDE; PROAPOPTOTIC MITOCHONDRIAL PROTEIN; SK2 CHANNEL; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; MITOCHONDRIAL MEMBRANE; MOUSE; NEUROPROTECTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; PROTEIN SECRETION; PROTEIN TARGETING;

ANIMALS; CELL LINE; CELL MEMBRANE; GLUTAMIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDES; POTASSIUM; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 84876209070     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.453522     Document Type: Article

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