Restricted expression of the gap junctional protein connexin 43 in the arterial system of the rat

Journal of Anatomy

Volumn 192, Issue 4, 1998, Pages 583-593

  Hong, Tao ^a   Hill, Caryl E ^a  

^a Biology and Environment   (Australia)

Author keywords

Endothelia; Gap junctions; Media; Vasculature

Indexed keywords

CONNEXIN 43; GAP JUNCTION PROTEIN;

ANIMAL TISSUE; ARTERY; ARTERY MEDIA; ARTERY RESISTANCE; ARTICLE; BASILAR ARTERY; CELL JUNCTION; CONFOCAL LASER MICROSCOPY; CORONARY ARTERY; ENDOTHELIUM CELL; FEMALE; HEPATIC ARTERY; IMMUNOFLUORESCENCE; MALE; MESENTERIC ARTERY; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; STAINING; TAIL ARTERY; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASCULARIZATION;

ANIMALS; AORTA, ABDOMINAL; AORTA, THORACIC; BASILAR ARTERY; CAROTID ARTERIES; CEREBRAL ARTERIES; CONNEXIN 43; CORONARY VESSELS; ELASTIC TISSUE; ENDOTHELIUM, VASCULAR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GAP JUNCTIONS; HEPATIC ARTERY; MALE; MESENTERIC ARTERY, SUPERIOR; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED WKY; TAIL;

ANIMALIA;

EID: 0031824584     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0021878298003653     Document Type: Article

References (34)

1. BASTIDE B, NEYSES L, GANTEN D, PAUL M, WILLECKE K, TRAUB O (1993) Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions. Circulation Research 73, 1138-1149.
2. BENY JL, CONNAT JL (1992) An electron-microscopic study of smooth muscle cell dye coupling in the pig coronary arteries. Role of gap junctions. Circulation Research 70, 49-55.
3. BENY JL, GRIBI F (1989) Dye and electrical coupling of endothelial cells in situ. Tissue and Cell 21, 797-802.
4. BENY JL, PACICCA C (1994) Bidirectional electrical communication between smooth muscle and endothelial cells in the pig coronary artery. American Journal of Physiology 266, H1465-1472.
5. BEYER EC, REED KE, WESTPHALE EM, KANTER HL, LARSON DM (1992) Molecular cloning and expression of rat connexin40, a gap junction protein expressed in vascular smooth muscle. Journal of Membrane Biology 127, 69-76.
6. BLACKBURN JP, CONNAT JL, SEVERS NJ, GREEN CR (1997) Connexin43 gap junction levels during development of the thoracic aorta are temporally correlated with elastic laminae deposition and increased blood pressure. Cell Biology International 21, 87-97.
7. BRUZZONE R, HAEFLIGER JA, GIMLICH RL, PAUL DL (1993) Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Molecular Biology of the Cell 4, 7-20.
8. BRUZZONE R, WHITE TW, PAUL DL (1996) Connections with connexins: the molecular basis of direct intercellular signaling. European Journal of Biochemistry 238, 1-27.
9. CHAYTOR AT, EWANS WH, GRIFFITH TM (1997) Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. Journal of Physiology 503, 992-110.
10. CHRIST GJ, SPRAY DC, EL-SABBAN M, MOORE LK, BRINK PR (1996) Gap junctions in vascular tissues-evaluating the role of intercellular communication in the modulation of vasomotor tone. Circulation Research 79, 631-646.
11. DELORME B, DAHL E, JARRY-GUICHARD T, BRIAND JP, WILLECKE K, GROS D et al. (1997) Expression pattern of connexin gene products at the early development stages of the mouse cardiovascular system. Circulation Research 81, 423-437.
12. GOURDIE RG (1995) A map of the heart: gap junctions, connexin diversity and retroviral studies of conduction myocyte lineage. Clinical Science 88, 257-262.
13. GREEN CR, PETERS NS, GOURDIE RG, ROTHERY S, SEVERS NJ (1993) Validation of immunohistochemical quantification in confocal scanning laser microscopy : a comparative assessment of gap junction size with confocal and ultrastructural techniques. Journal of Histochemistry and Cytochemistry 41, 1339-1349.
14. GROS D, JARRY-GUICHARD T, VELDE IT, DE MAZIERE A, VAN KEMPEN MJA, DAVOUST et al. (1994) Restricted distribution of connexin40, a gap junctional protein, in mammalian heart. Circulation Research 74, 839-851.
15. HIRST G, EDWARDS F (1989) Sympathetic neuroeffector transmission in arteries and arterioles. Physiological Reviews 69, 549-604.
16. KUMAR NM, GILULAR NB (1996) The gap junction communication channel. Cell 84, 381-388.
17. LAING JG, WESTPHALE EM, ENGELMANN GL, BEYER EC (1994) Characterization of the gap junction protein, connexin45. Journal of Membrane Biology 139, 31-40.
18. LARSON DM, HAUDENSCHILD CC, BEYER EC (1990) Gap junction messenger RNA expression by vascular wall cells. Circulation Research 66, 1074-1080.
19. LASH JA, CRITSER ES, PRESSLER ML (1990) Cloning of a gap junctional protein from vascular smooth muscle and expression in two-cell mouse embryos. Journal of Biological Chemistry 265, 13113-13117.
20. LITTLE TL, BEYER EC, DULING BR (1995a) Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo. American Journal of Physiology 268, H729-739.
21. LITTLE TL, XIA J, DULING BR ( 1995b) Dye tracers define differential endothelial and smooth muscle coupling pattern within the arteriolar wall. Circulation Research 76, 498-504.
22. MIKKELSEN HB, HUIZINGA JD, THUNEBERG L, RUMESSEN JJ (1993) Immunohistochemical localization of a gap junction protein (connexin43) in the muscularis externa of murine, canine, and human intestine. Cell and Tissue Research 274, 249-256.
23. MOORE LK, BURT JM (1995) Gap junction function in vascular smooth muscle: influence of serotonin. American Journal of Physiology 269, H1481-1489.
24. PEPPER MS, MONTESANO R, EL AOUMARI A, GROS D, ORCI L, MEDA P (1992) Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. American Journal of Physiology 262, C1246-1257.
25. POLACEK D, BECH F, MCKENSEY JF, DAVIES PF (1997) Effects of hypercholesterolemia, balloon injury and their combination. Journal of Vascular Research 34, 19-30.
26. REED KE, WESTPHALE EM, LARSON DM, WANG HZ, VEENSTRA RD, BEYER EC (1993) Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. Journal of Clinical Investigation 91, 997-1004.
27. SEGAL SS, BENY JL (1992) Intracellular recording and dye transfer in arterioles during blood flow control. American Journal of Physiology 263, H1-H7.
28. SEVERS NJ (1995) Cardiac muscle cell interaction: from microanatomy to the molecular make-up of the gap junction. Histology and Histopathology 10, 481-501.
29. SOSINSKY GE (1996) Molecular organization of gap junction membrane channels. Journal of Bioenergetics and Biomembranes 28, 297-309.
30. STUTENKEMPER R, GEISSE S, SCHWARZ HL, LOOK J, TRAUB O, NICHOLSON BJ et al. (1992) The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43. Experimental Cell Research 201, 43-54.
31. VERHEULE S, VAN KEMPEN MJA, TE WELSCHER PHJA, KWAK BR, JONGSMA HJ (1997) Characterization of gap junction channels in adult rabbit atrial and ventricular myocardium. Circulation Research 80, 673-681.
32. WILLECKE K, HAUBRICH S (1996) Connexin expression system: to what extent do they reflect the situation in the animal ? Journal of Bioenergetics and Biomembranes 28, 319-326.
33. YEH HI, DUPONT E, COPPEN S, SEVERS NJ (1997a) Gap junction localization and connexin expression in cytochemically identified endothelial cells of arterial tissue. Journal of Histochemistry and Cytochemistry 45, 539-550.
34. YEH HI, LUPU F, DUPONT E, SEVERS NJ (1997b) Upregulation of connexin43 gap junctions between smooth muscle cells after balloon catheter injury in the rat carotid artery. Arteriosclerosis, Thrombosis, and Vascular Biology 17, 3174-3184.