-
1
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
[1] Mendell, J.T., Olson, E.N., MicroRNAs in stress signaling and human disease. Cell 148 (2012), 1172–1187.
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
2
-
-
81355142141
-
Non-coding RNAs in human disease
-
[2] Esteller, M., Non-coding RNAs in human disease. Nat. Rev. Genet. 12 (2011), 861–874.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
3
-
-
84867900638
-
Long non-coding RNAs and cancer: a new frontier of translational research?
-
[3] Spizzo, R., Almeida, M.I., Colombatti, A., et al. Long non-coding RNAs and cancer: a new frontier of translational research?. Oncogene 31 (2012), 4577–4587.
-
(2012)
Oncogene
, vol.31
, pp. 4577-4587
-
-
Spizzo, R.1
Almeida, M.I.2
Colombatti, A.3
-
4
-
-
84865812140
-
Genomics. ENCODE project writes eulogy for junk DNA
-
[4] Pennisi, E., Genomics. ENCODE project writes eulogy for junk DNA. Science 337 (2012), 1159–1161.
-
(2012)
Science
, vol.337
, pp. 1159-1161
-
-
Pennisi, E.1
-
5
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
[5] Dunham, I., An integrated encyclopedia of DNA elements in the human genome. Nature 489 (2012), 57–74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
-
6
-
-
84865757142
-
Landscape of transcription in human cells
-
[6] Djebali, S., Davis, C.A., Merkel, A., et al. Landscape of transcription in human cells. Nature 489:7414 (2012), 101–108.
-
(2012)
Nature
, vol.489
, Issue.7414
, pp. 101-108
-
-
Djebali, S.1
Davis, C.A.2
Merkel, A.3
-
7
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
[7] Fabian, M.R., Sonenberg, N., Filipowicz, W., Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 79 (2010), 351–379.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
8
-
-
85063656341
-
Targeting microRNAs in cancer: rationale, within cell-cycle promoters
-
[8] Garzon, R., Marcucci, G., Croce, C.M., Targeting microRNAs in cancer: rationale, within cell-cycle promoters. Nat. Genet. 43 (2011), 621–629.
-
(2011)
Nat. Genet.
, vol.43
, pp. 621-629
-
-
Garzon, R.1
Marcucci, G.2
Croce, C.M.3
-
9
-
-
84862185932
-
The therapeutic potential of microRNAs in cancer
-
[9] Thorsen, S.B., Obad, S., Jensenet, N.F., et al. The therapeutic potential of microRNAs in cancer. Cancer J. 18 (2012), 275–284.
-
(2012)
Cancer J.
, vol.18
, pp. 275-284
-
-
Thorsen, S.B.1
Obad, S.2
Jensenet, N.F.3
-
10
-
-
84868475728
-
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles
-
[10] Van Rooij, E., Olson, E.N., MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat. Rev. Drug Discov. 11 (2012), 860–872.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 860-872
-
-
Van Rooij, E.1
Olson, E.N.2
-
11
-
-
85063658097
-
Targeting long non-coding RNA to therapeutically upregulate gene strategies and challenges
-
[11] Wahlestedt, C., Targeting long non-coding RNA to therapeutically upregulate gene strategies and challenges. Nat. Rev. Drug Discov. 9 (2012), 775–789.
-
(2012)
Nat. Rev. Drug Discov.
, vol.9
, pp. 775-789
-
-
Wahlestedt, C.1
-
12
-
-
84864503916
-
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
-
[12] Fabbri, M., MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), E2110–E2116.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. E2110-E2116
-
-
Fabbri, M.1
-
13
-
-
79953301730
-
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
-
[13] Vickers, K.C., Palmisano, B.T., Shoucri, B.M., et al. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat. Cell Biol. 13 (2011), 423–433.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 423-433
-
-
Vickers, K.C.1
Palmisano, B.T.2
Shoucri, B.M.3
-
14
-
-
81855224576
-
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
-
[14] Kasinski, A.L., Slack, F.J., Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 11 (2011), 849–864.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 849-864
-
-
Kasinski, A.L.1
Slack, F.J.2
-
15
-
-
84878595514
-
Control of metastatic progression by microRNA regulatory networks
-
[15] Pencheva, N., Tavazoie, S.F., Control of metastatic progression by microRNA regulatory networks. Nat. Cell Biol. 15 (2013), 546–554.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 546-554
-
-
Pencheva, N.1
Tavazoie, S.F.2
-
16
-
-
84855813448
-
microRNA regular that mediates endothelial recruitment and metastasis by cancer cells
-
[16] Png, K.J., Halberg, N., Yoshida, M., M, et al. microRNA regular that mediates endothelial recruitment and metastasis by cancer cells. Nature 481 (2012), 190–194.
-
(2012)
Nature
, vol.481
, pp. 190-194
-
-
Png, K.J.1
Halberg, N.2
Yoshida, M.3
M4
-
17
-
-
84880570961
-
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling
-
[17] Song, S.J., MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell 154 (2013), 311–324.
-
(2013)
Cell
, vol.154
, pp. 311-324
-
-
Song, S.J.1
-
18
-
-
84859811931
-
Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer
-
[18] Uhlmann, S., Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. Mol. Syst. Biol., 8, 2012, 570.
-
(2012)
Mol. Syst. Biol.
, vol.8
, pp. 570
-
-
Uhlmann, S.1
-
19
-
-
84862831034
-
Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells
-
886–896e9
-
[19] Almeida, M.I., Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. Gastroenterology, 142, 2012 886–896e9.
-
(2012)
Gastroenterology
, vol.142
-
-
Almeida, M.I.1
-
20
-
-
79952717616
-
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
-
[20] Melo, S., et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 4394–4399.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 4394-4399
-
-
Melo, S.1
-
21
-
-
83255192141
-
Developing therapeutic microRNAs for cancer
-
[21] Bader, A.G., Brown, D., Stoudemire, J., et al. Developing therapeutic microRNAs for cancer. Gene Ther. 18 (2011), 1121–1126.
-
(2011)
Gene Ther.
, vol.18
, pp. 1121-1126
-
-
Bader, A.G.1
Brown, D.2
Stoudemire, J.3
-
22
-
-
84861473531
-
Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticle
-
[22] Tivnan, A., Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticle. PLoS ONE, 7, 2012, e38129.
-
(2012)
PLoS ONE
, vol.7
, pp. e38129
-
-
Tivnan, A.1
-
23
-
-
79957900919
-
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
-
[23] Trang, P., et al. Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol. Ther. 19 (2011), 1116–1122.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1116-1122
-
-
Trang, P.1
-
24
-
-
79961020784
-
Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways
-
[24] Chen, L., Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways. Mol. Ther. 19 (2011), 1521–1528.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1521-1528
-
-
Chen, L.1
-
25
-
-
84869219338
-
miR-34-a microRNA replacement therapy is headed to the clinic Front
-
[25] Bader, A.G., miR-34-a microRNA replacement therapy is headed to the clinic Front. Genet, 3, 2012, 120.
-
(2012)
Genet
, vol.3
, pp. 120
-
-
Bader, A.G.1
-
26
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
[26] Janssen, H.L., et al. Treatment of HCV infection by targeting microRNA. N. Engl. J. Med. 368 (2013), 1685–1694.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
-
27
-
-
84865403336
-
LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas
-
(km)
-
[27] Zhang, Y., et al. LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas. Blood 120 (2012), 1678–1686 (km).
-
(2012)
Blood
, vol.120
, pp. 1678-1686
-
-
Zhang, Y.1
-
28
-
-
84855417964
-
Rapid generation of microRNA sponges for microRNA inhibition
-
[28] Kluiver, J., et al. Rapid generation of microRNA sponges for microRNA inhibition. PLoS ONE, 7, 2012, e29275.
-
(2012)
PLoS ONE
, vol.7
, pp. e29275
-
-
Kluiver, J.1
-
29
-
-
84878113369
-
The shaping and functional consequences of the microRNA landscape in breast cancer
-
[29] Dvinge, H., The shaping and functional consequences of the microRNA landscape in breast cancer. Nature 497 (2013), 378–382.
-
(2013)
Nature
, vol.497
, pp. 378-382
-
-
Dvinge, H.1
-
30
-
-
84861577379
-
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
-
[30] Lehmann, S.M., et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat. Neurosci. 15 (2012), 827–835.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 827-835
-
-
Lehmann, S.M.1
-
31
-
-
84877244539
-
Biotech comes to its ‘antisenses’ after hard-won drug approval
-
[31] Jiang, K., Biotech comes to its ‘antisenses’ after hard-won drug approval. Nat. Med., 19, 2013, 252.
-
(2013)
Nat. Med.
, vol.19
, pp. 252
-
-
Jiang, K.1
-
32
-
-
84877649531
-
Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells
-
[32] Ding, L., Hu, X.M., Wu, H., et al. Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells. Can. Bio Med. 10 (2013), 16–21.
-
(2013)
Can. Bio Med.
, vol.10
, pp. 16-21
-
-
Ding, L.1
Hu, X.M.2
Wu, H.3
-
33
-
-
84880596133
-
The effect of Bcl-2 siRNA combined with miR-15a oligonucleotides on the growth of Raji cells
-
[33] Hu, X., Jung, E.J., Calin, G.A., The effect of Bcl-2 siRNA combined with miR-15a oligonucleotides on the growth of Raji cells. Med. Oncol., 30, 2013, 430.
-
(2013)
Med. Oncol.
, vol.30
, pp. 430
-
-
Hu, X.1
Jung, E.J.2
Calin, G.A.3
-
34
-
-
84879177004
-
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11
-
[34] Bockhorn, J., Stoudemire, J., Lammers, P., MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat. Commun., 4, 2013, 1393.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1393
-
-
Bockhorn, J.1
Stoudemire, J.2
Lammers, P.3
-
35
-
-
84875369248
-
Circular RNAs are a large class of animal RNAs with regulatory potency
-
[35] Memczal, S., Poliseno, L., Tay, Y., Circular RNAs are a large class of animal RNAs with regulatory potency. Nature 495 (2013), 333–338.
-
(2013)
Nature
, vol.495
, pp. 333-338
-
-
Memczal, S.1
Poliseno, L.2
Tay, Y.3
-
36
-
-
85063658309
-
CCAT2, a Novel Non-coding RNA Mapping to 8q24
-
[36] Ling, H., Jung, E.J., Calin, G.A., CCAT2, a Novel Non-coding RNA Mapping to 8q24. 2013.
-
(2013)
-
-
Ling, H.1
Jung, E.J.2
Calin, G.A.3
-
37
-
-
85063654749
-
A ceRNA hypothesis: the miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells
-
[37] Salmena, L., Poliseno, L., Tay, Y., A ceRNA hypothesis: the miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells. Cancer 154 (2013), 311–324.
-
(2013)
Cancer
, vol.154
, pp. 311-324
-
-
Salmena, L.1
Poliseno, L.2
Tay, Y.3
-
38
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
[38] Poliseno, L., Pencheva, N., Tavazoie, S.F., A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465 (2010), 1033–1038.
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Pencheva, N.2
Tavazoie, S.F.3
-
39
-
-
85063656542
-
Extensive and coordinated transcription of noncoding RNAs expression
-
[39] Hung, T., Li, C.H., Chen, Y., Extensive and coordinated transcription of noncoding RNAs expression. Nat. Rev. Drug Discov. 12 (2013), 433–446.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 433-446
-
-
Hung, T.1
Li, C.H.2
Chen, Y.3
-
40
-
-
84864439453
-
Targeting nuclear RNA for in vivo correction of myotonic dystrophy
-
[40] Wheeler, T.M., Kino, T., Hurt, D.E., et al. Targeting nuclear RNA for in vivo correction of myotonic dystrophy. Nature 488 (2012), 111–115.
-
(2012)
Nature
, vol.488
, pp. 111-115
-
-
Wheeler, T.M.1
Kino, T.2
Hurt, D.E.3
-
41
-
-
84873451950
-
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells
-
[41] Gutschner, T., The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Res. 73 (2013), 1180–1189.
-
(2013)
Cancer Res.
, vol.73
, pp. 1180-1189
-
-
Gutschner, T.1
-
42
-
-
77951638287
-
Noncoding RNA Gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor
-
[42] Kino, T., Hurt, D.E., Ichijo, T., et al. Noncoding RNA Gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci. Signal, 3, 2010, 8.
-
(2010)
Sci. Signal
, vol.3
, pp. 8
-
-
Kino, T.1
Hurt, D.E.2
Ichijo, T.3
-
43
-
-
84860385629
-
AntagoNATs boost gene expression
-
[43] Rusk, N., AntagoNATs boost gene expression. Nat. Methods, 9, 2012, 437.
-
(2012)
Nat. Methods
, vol.9
, pp. 437
-
-
Rusk, N.1
-
44
-
-
84860353437
-
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
-
[44] Modarresi, F., et al. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat. Biotech. 30 (2012), 453–459.
-
(2012)
Nat. Biotech.
, vol.30
, pp. 453-459
-
-
Modarresi, F.1
-
45
-
-
84866080241
-
Regulatory watch: pioneering gene therapy on brink of approval
-
[45] Flemming, A., Regulatory watch: pioneering gene therapy on brink of approval. Nat. Rev. Drug Discov., 11, 2012, 664.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 664
-
-
Flemming, A.1
-
46
-
-
84869040765
-
Europe gives gene therapy the green light
-
[46] Gruber, K., Europe gives gene therapy the green light. Lancet, 380, 2012, e10.
-
(2012)
Lancet
, vol.380
, pp. e10
-
-
Gruber, K.1
-
47
-
-
84875372911
-
Natural RNA circles function as efficient microRNA sponges
-
[47] Hansen, T.B., Natural RNA circles function as efficient microRNA sponges. Nature 495 (2013), 384–388.
-
(2013)
Nature
, vol.495
, pp. 384-388
-
-
Hansen, T.B.1
-
48
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
-
[48] Guttman, M., Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458 (2009), 223–227.
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
-
49
-
-
84874368349
-
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
-
[49] Lai, F., et al. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature 494 (2013), 497–501.
-
(2013)
Nature
, vol.494
, pp. 497-501
-
-
Lai, F.1
-
50
-
-
84867334962
-
Cell-to-cell miRNA transfer: from body homeostasis to therapy
-
[50] Redis, R.S., Calin, S., Yang, Y., et al. Cell-to-cell miRNA transfer: from body homeostasis to therapy. Pharmacol. Ther. 136 (2012), 169–174.
-
(2012)
Pharmacol. Ther.
, vol.136
, pp. 169-174
-
-
Redis, R.S.1
Calin, S.2
Yang, Y.3
-
51
-
-
80053175966
-
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
-
[51] Yang, M., et al. Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol. Cancer, 10, 2011, 117.
-
(2011)
Mol. Cancer
, vol.10
, pp. 117
-
-
Yang, M.1
-
52
-
-
84883742665
-
MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
-
[52] Yang, S., et al. MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1. Oncogene 32 (2012), 4294–4303.
-
(2012)
Oncogene
, vol.32
, pp. 4294-4303
-
-
Yang, S.1
-
53
-
-
84867396410
-
Diagnostic performance of PCA3 to detect prostate cancer in men with increased prostate specific antigen: a prospective study of 1,962 cases
-
[53] Crawford, E.D., Diagnostic performance of PCA3 to detect prostate cancer in men with increased prostate specific antigen: a prospective study of 1,962 cases. J. Urol. 188 (2012), 1726–1731.
-
(2012)
J. Urol.
, vol.188
, pp. 1726-1731
-
-
Crawford, E.D.1
|