Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa

Stem Cell Research

Volumn 21, Issue , 2017, Pages 58-70

  Sharma, Tasneem P ^a   Wiley, Luke A ^a   Whitmore, S Scott ^a   Anfinson, Kristin R ^a   Cranston, Cathryn M ^a   Oppedal, Douglas J ^a   Daggett, Heather T ^a   Mullins, Robert F ^a   Tucker, Budd A ^a   Stone, Edwin M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Autophagy; Induced pluripotent stem cells; Oxidative stress; Retinal organoids; Retinitis pigmentosa; TRNT 1

Indexed keywords

CHLOROQUINE; ISOPROTEIN; KRUPPEL LIKE FACTOR 4; RNA POLYMERASE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRNT1 PROTEIN; UNCLASSIFIED DRUG; LAMP1 PROTEIN, HUMAN; LIGHT CHAIN 3, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NUCLEOTIDYLTRANSFERASE; TRNT1 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DIFFERENTIATION; CELL PROLIFERATION; CLEARANCE; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENETIC IDENTIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; INDUCED PLURIPOTENT STEM CELL; MOLECULAR PATHOLOGY; ONCOGENE C MYC; OXIDATIVE STRESS; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN FOLDING; RETINITIS PIGMENTOSA; SKIN FIBROBLAST; WESTERN BLOTTING; WHOLE EXOME SEQUENCING; CYTOLOGY; GENETICS; METABOLISM; MUTATION; ORGANOID; PATHOLOGY; PATHOPHYSIOLOGY; RETINA;

AUTOPHAGOSOMES; AUTOPHAGY; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NUCLEOTIDYLTRANSFERASES; ORGANOIDS; OXIDATIVE STRESS; RETINA; RETINITIS PIGMENTOSA;

EID: 85017158791     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2017.03.005     Document Type: Article

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