Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups

Cell Stem Cell

Volumn 18, Issue 6, 2016, Pages 769-781

  Parfitt, David A ^a   Lane, Amelia ^a   Ramsden, Conor M ^a,b   Carr, Amanda Jayne F ^a   Munro, Peter M ^a   Jovanovic, Katarina ^a   Schwarz, Nele ^a   Kanuga, Naheed ^a   Muthiah, Manickam N ^a,b   Hull, Sarah ^a,b   Gallo, Jean Marc ^c   Da Cruz, Lyndon ^a,b   Moore, Anthony T ^a,b   Hardcastle, Alison J ^a   Coffey, Peter J ^a   Cheetham, Michael E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CELL PROTEIN; CEP290 PROTEIN; MORPHOLINO OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; CEP290 PROTEIN, HUMAN; EYE PROTEIN; MESSENGER RNA; OPSIN; RAB PROTEIN; RAB8A PROTEIN, HUMAN; RPGR PROTEIN, HUMAN; TUMOR ANTIGEN; TUMOR PROTEIN;

ALTERNATIVE RNA SPLICING; ANTISENSE THERAPY; ARTICLE; CELL DIFFERENTIATION; CELLS BY BODY ANATOMY; CONGENITAL BLINDNESS; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; INHERITANCE; OPTIC DISK CUP; PHENOTYPE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN TRANSPORT; RETINA; RETINAL PIGMENT EPITHELIUM; BLINDNESS; CILIUM; CYTOLOGY; DRUG EFFECTS; EXON; FIBROBLAST; GENETICS; LEBER CONGENITAL AMAUROSIS; MALE; METABOLISM; OPTIC DISK; ORGANOGENESIS; PATHOLOGY; RNA SPLICING; ULTRASTRUCTURE; VERTEBRATE PHOTORECEPTOR CELL;

ANTIGENS, NEOPLASM; BLINDNESS; CELL DIFFERENTIATION; CILIA; EXONS; EYE PROTEINS; FIBROBLASTS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INHERITANCE PATTERNS; LEBER CONGENITAL AMAUROSIS; MALE; MORPHOLINOS; NEOPLASM PROTEINS; OPSINS; OPTIC DISK; ORGANOGENESIS; PHOTORECEPTOR CELLS, VERTEBRATE; RAB GTP-BINDING PROTEINS; RETINAL PIGMENT EPITHELIUM; RNA SPLICING; RNA, MESSENGER;

EID: 84963537954     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.03.021     Document Type: Article

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