A Splice Variant of the Human CCA-adding Enzyme with Modified Activity

Journal of Molecular Biology

Volumn 366, Issue 4, 2007, Pages 1258-1265

  Lizano, Esther ^a   Schuster, Jens ^b   Müller, Martin ^a   Kelso, Janet ^c   Mörl, Mario ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

^c MAX PLANCK INSTITUTE FOR EVOLUTIONARY ANTHROPOLOGY   (Germany)

Author keywords

alternative splicing; CC adding enzyme; CCA adding enzyme; tRNA nucleotidyltransferase

Indexed keywords

CCA ADDING ENZYME; COMPLEMENTARY DNA; ENZYME VARIANT; RNA POLYMERASE; TRANSFER RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL; COMPUTER MODEL; DATA BASE; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION;

EID: 33846573777     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.12.016     Document Type: Article

References (26)

1. Sprinzl M., and Cramer F. The -C-C-A end of tRNA and its role in protein biosynthesis. Prog. Nucl. Acid Res. Mol. Biol. 22 (1979) 1-69
2. Schürer H., Schiffer S., Marchfelder A., and Mörl M. This is the end: processing, editing and repair at the tRNA 3′-terminus. Biol. Chem. 382 (2001) 1147-1156
3. Weiner A.M. tRNA maturation: RNA polymerization without a nucleic acid template. Curr. Biol. 14 (2004) R883-R885
4. Schimmel P., and Yang X.L. Two classes give lessons about CCA. Nature Struct. Mol. Biol. 11 (2004) 807-808
5. Tomita K., and Weiner A.M. Collaboration between CC- and A-adding enzymes to build and repair the 3′-terminal CCA of tRNA in Aquifex aeolicus. Science 294 (2001) 1334-1336
6. Tomita K., and Weiner A.M. Closely related CC- and A-adding enzymes collaborate to construct and repair the 3′-terminal CCA of tRNA in Synechocystis sp. and Deinococcus radiodurans. J. Biol. Chem. 277 (2002) 48192-48198
7. Reichert A.S., Thurlow D.L., and Mörl M. A eubacterial origin for the human tRNA nucleotidyltransferase?. Biol. Chem. 382 (2001) 1431-1438
8. Nagaike T., Suzuki T., Tomari Y., Takemoto-Hori C., Negayama F., Watanabe K., and Ueda T. Identification and characterization of mammalian mitochondrial tRNA nucleotidyltransferases. J. Biol. Chem. 276 (2001) 40041-40049
9. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403-410
10. Augustin M.A., Reichert A.S., Betat H., Huber R., Mörl M., and Steegborn C. Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization. J. Mol. Biol. 328 (2003) 985-994
11. Modrek B., and Lee C. A genomic view of alternative splicing. Nature Genet. 30 (2002) 13-19
12. Sorek R., Shamir R., and Ast G. How prevalent is functional alternative splicing in the human genome?. Trends Genet. 20 (2004) 68-71
13. Berget S.M. Exon recognition in vertebrate splicing. J. Biol. Chem. 270 (1995) 2411-2414
14. Moore M.J., Query C.C., and Sharp P.A. Splicing of precursors to mRNAs by the spliceosome. In: Gesteland R.F., and Atkins J.F. (Eds). The RNA World (1993), Cold Spring Harbour Laboratory Press, Cold Spring Harbour, NY 303-357
15. Roca X., Sachidanandam R., and Krainer A.R. Intrinsic differences between authentic and cryptic 5′ splice sites. Nucl. Acids Res. 31 (2003) 6321-6333
16. Shapiro M.B., and Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucl. Acids Res. 15 (1987) 7155-7174
17. Sorek R., and Ast G. Intronic sequences flanking alternatively spliced exons are conserved between human and mouse. Genome Res. 13 (2003) 1631-1637
18. Lewis B.P., Green R.E., and Brenner S.E. Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc. Natl Acad. Sci. USA 100 (2003) 189-192
19. Li F., Xiong Y., Wang J., Cho H.D., Tomita K., Weiner A.M., and Steitz T.A. Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Cell 111 (2002) 815-824
20. Tomita K., Fukai S., Ishitani R., Ueda T., Takeuchi N., Vassylyev D.G., and Nureki O. Structural basis for template-independent RNA polymerization. Nature 430 (2004) 700-704
21. Betat H., Rammelt C., Martin G., and Mörl M. Exchange of regions between bbacterial poly(A) polymerase and CCA adding enzyme generates altered specificities. Mol. Cell 15 (2004) 389-398
22. Blanchette M., Kent W.J., Riemer C., Elnitski L., Smit A.F., Roskin K.M., et al. Aligning multiple genomic sequences with the threaded blockset aligner. Genome Res. 14 (2004) 708-715
23. Schwartz S., Kent W.J., Smit A., Zhang Z., Baertsch R., Hardison R.C., et al. Human-mouse alignments with BLASTZ. Genome Res. 13 (2003) 103-107
24. Crooks G.E., Hon G., Chandonia J.M., and Brenner S.E. WebLogo: a sequence logo generator. Genome Res. 14 (2004) 1188-1190
25. Sorek R., Shemesh R., Cohen Y., Basechess O., Ast G., and Shamir R. A non-EST-based method for exon-skipping prediction. Genome Res. 14 (2004) 1617-1623
26. Mörl M., Lizano E., Willkomm D.K., and Hartmann R.K. Production of RNAs with homogeneous 5′ and 3′ ends. In: Hartmann R.K., Bindereif A., Schön A., and Westhof E. (Eds). Handbook of RNA Biochemistry vol. 1 (2005), Wiley-VCH, Weinheim 22-35 (2 vols)