FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells

Molecular and Cellular Biology

Volumn 37, Issue 8, 2017, Pages

  Yamauchi, Takayoshi ^a   Nishiyama, Masaaki ^a   Moroishi, Toshiro ^a   Kawamura, Atsuki ^a   Nakayama, Keiichi I ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Brain development; Iron regulation; Ligase; mTOR; Neural stem cell; Oxidative stress; SCF complex; Ubiquitination

Indexed keywords

F BOX AND LEUCINE RICH REPEAT PROTEIN 5; FERRIC ION; FERROUS ION; IRON REGULATORY PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN; NESTIN; REACTIVE OXYGEN METABOLITE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; F BOX PROTEIN; FBXL5 PROTEIN, MOUSE; IRON; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; MACROGLIA; MOUSE; MOUSE MUTANT; NEURAL STEM CELL; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; CYTOLOGY; GENE DELETION; KNOCKOUT MOUSE; MAMMALIAN EMBRYO; METABOLISM;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL PROLIFERATION; EMBRYO, MAMMALIAN; F-BOX PROTEINS; GENE DELETION; IRON; MICE, KNOCKOUT; NEURAL STEM CELLS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 85017143987     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00470-16     Document Type: Article

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