HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism

Journal of Biological Chemistry

Volumn 289, Issue 23, 2014, Pages 16430-16441

  Moroishi, Toshiro ^a   Yamauchi, Takayoshi ^a   Nishiyama, Masaaki ^a   Nakayama, Keiichi I ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; IRON; IRON COMPOUNDS; MAMMALS; METABOLISM; MOLECULAR BIOLOGY; PHYSIOLOGY;

DEGRADATION PATHWAYS; IRON REGULATORY PROTEINS; LEUCINE-RICH REPEATS; POST-TRANSCRIPTIONAL REGULATIONS; PROTEASOMAL DEGRADATION; SUBSTRATE RECOGNITION; UBIQUITIN-PROTEIN LIGASES; UPSTREAM REGULATION;

PROTEINS;

F BOX AND LEUCINE RICH REPEAT PROTEIN 5; FERROUS ION; PROTEIN HERC2; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; INHIBITION KINETICS; IRON METABOLISM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; PROTEOMICS; RNA INTERFERENCE; STEADY STATE; UPREGULATION;

E3 UBIQUITIN LIGASE; IRON METABOLISM; PROTEIN DEGRADATION; PROTEOMICS; UBIQUITYLATION (UBIQUITINATION);

BASE SEQUENCE; DNA PRIMERS; F-BOX PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HELA CELLS; HUMANS; HYDROLYSIS; IRON; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84902209441     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.541490     Document Type: Article

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