A critical role for mTORC1 in erythropoiesis and anemia

eLife

Volumn 3, Issue , 2014, Pages e01913-

  Knight, Zachary A ^a   Schmidt, Sarah F ^a   Birsoy, Kivanc ^a   Tan, Keith ^a   Friedman, Jeffrey M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

anemia; cell biology; erythropoiesis; human biology; medicine; mouse; mTOR; mTORC1; RBC

Indexed keywords

IRON; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; RPTOR PROTEIN, MOUSE; S6 KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE; TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADULT; ANEMIA; ANIMAL; ANTAGONISTS AND INHIBITORS; DEFICIENCY; DRUG EFFECTS; ERYTHROPOIESIS; GENE DELETION; HUMAN; K562 CELL LINE; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION; RETICULOCYTE; SIGNAL TRANSDUCTION; SURVIVAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; ANEMIA; ANIMALS; ERYTHROPOIESIS; GENE DELETION; HUMANS; IRON; K562 CELLS; MICE; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; RETICULOCYTES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84964315439     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01913     Document Type: Article

References (0)