메뉴 건너뛰기




Volumn 8, Issue MAR, 2017, Pages

Role of anti-osteopontin antibodies in multiple sclerosis and experimental autoimmune encephalomyelitis

Author keywords

Autoantibodies; Experimental autoimmune encephalomyelitis; Multiple sclerosis; osteopontin; Vaccination

Indexed keywords

AUTOANTIBODY; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; OSTEOPONTIN;

EID: 85017092388     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00321     Document Type: Article
Times cited : (35)

References (44)
  • 1
    • 84855967278 scopus 로고    scopus 로고
    • Immune-mediated CNS diseases: a review on nosological classification and clinical features
    • Zettl UK, Stüve O, Patejdl R. Immune-mediated CNS diseases: a review on nosological classification and clinical features. Autoimmun Rev (2012) 11(3):167-73. doi: 10.1016/j.autrev.2011.05.008
    • (2012) Autoimmun Rev , vol.11 , Issue.3 , pp. 167-173
    • Zettl, U.K.1    Stüve, O.2    Patejdl, R.3
  • 2
    • 0028928973 scopus 로고
    • The natural history of multiple sclerosis
    • Weinshenker BG. The natural history of multiple sclerosis. Neurol Clin (1995) 13(1):119-46
    • (1995) Neurol Clin , vol.13 , Issue.1 , pp. 119-146
    • Weinshenker, B.G.1
  • 3
    • 84916604715 scopus 로고    scopus 로고
    • Biomarkers of therapeutic response in multiple sclerosis: current status
    • Harris VK, Sadiq SA. Biomarkers of therapeutic response in multiple sclerosis: current status. Mol Diagn Ther (2014) 18(6):605-17. doi:10.1007/s40291-014-0117-0
    • (2014) Mol Diagn Ther , vol.18 , Issue.6 , pp. 605-617
    • Harris, V.K.1    Sadiq, S.A.2
  • 4
    • 79960720555 scopus 로고    scopus 로고
    • The role of osteopontin in neurodegenerative diseases
    • Carecchio M, Comi C. The role of osteopontin in neurodegenerative diseases. J Alzheimers Dis (2011) 25(2):179-85. doi:10.3233/JAD-2011-102151
    • (2011) J Alzheimers Dis , vol.25 , Issue.2 , pp. 179-185
    • Carecchio, M.1    Comi, C.2
  • 5
    • 0043245084 scopus 로고    scopus 로고
    • Osteopontin: a bridge between bone and the immune system
    • Gravallese EM. Osteopontin: a bridge between bone and the immune system. J Clin Invest (2003) 112(2):147-9. doi:10.3233/JAD-2011-102151
    • (2003) J Clin Invest , vol.112 , Issue.2 , pp. 147-149
    • Gravallese, E.M.1
  • 6
    • 21044457664 scopus 로고    scopus 로고
    • Osteopontin gene haplotypes correlate with multiple sclerosis development and progression
    • Chiocchetti A, Comi C, Indelicato M, Castelli L, Mesturini R, Bensi T, et al. Osteopontin gene haplotypes correlate with multiple sclerosis development and progression. J Neuroimmunol (2005) 163(1-2):172-8. doi:10.1016/j.jneuroim.2005.02.020
    • (2005) J Neuroimmunol , vol.163 , Issue.1-2 , pp. 172-178
    • Chiocchetti, A.1    Comi, C.2    Indelicato, M.3    Castelli, L.4    Mesturini, R.5    Bensi, T.6
  • 7
    • 46949088027 scopus 로고    scopus 로고
    • Circulating levels of osteopontin, osteoprotegerin, total soluble receptor activator of nuclear factor-kappa B ligand, and high-sensitivity C-reactive protein in patients with active rheumatoid arthritis randomized to etanercept alone or in combination with methotrexate
    • Sennels H, Sørensen S, Ostergaard M, Knudsen L, Hansen M, Skjødt H, et al. Circulating levels of osteopontin, osteoprotegerin, total soluble receptor activator of nuclear factor-kappa B ligand, and high-sensitivity C-reactive protein in patients with active rheumatoid arthritis randomized to etanercept alone or in combination with methotrexate. Scand J Rheumatol (2008) 37(4):241-7. doi:10.1080/03009740801910320
    • (2008) Scand J Rheumatol , vol.37 , Issue.4 , pp. 241-247
    • Sennels, H.1    Sørensen, S.2    Ostergaard, M.3    Knudsen, L.4    Hansen, M.5    Skjødt, H.6
  • 8
    • 13444253766 scopus 로고    scopus 로고
    • Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus
    • D'Alfonso S, Barizzone N, Giordano M, Chiocchetti A, Magnani C, Castelli L, et al. Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus. Arthritis Rheum (2005) 52(2):539-47. doi:10.1002/art.20808
    • (2005) Arthritis Rheum , vol.52 , Issue.2 , pp. 539-547
    • D'Alfonso, S.1    Barizzone, N.2    Giordano, M.3    Chiocchetti, A.4    Magnani, C.5    Castelli, L.6
  • 9
    • 33846446710 scopus 로고    scopus 로고
    • High plasma osteopontin levels in patients with inflammatory bowel disease
    • Mishima R, Takeshima F, Sawai T, Ohba K, Ohnita K, Isomoto H, et al. High plasma osteopontin levels in patients with inflammatory bowel disease. J Clin Gastroenterol (2007) 41(2):167-72. doi:10.1097/MCG.0b013e31802d6268
    • (2007) J Clin Gastroenterol , vol.41 , Issue.2 , pp. 167-172
    • Mishima, R.1    Takeshima, F.2    Sawai, T.3    Ohba, K.4    Ohnita, K.5    Isomoto, H.6
  • 10
    • 0035941106 scopus 로고    scopus 로고
    • The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
    • Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (2001) 294(5547):1731-5. doi:10.1126/science.1062960
    • (2001) Science , vol.294 , Issue.5547 , pp. 1731-1735
    • Chabas, D.1    Baranzini, S.E.2    Mitchell, D.3    Bernard, C.C.4    Rittling, S.R.5    Denhardt, D.T.6
  • 11
    • 79751513658 scopus 로고    scopus 로고
    • The role of osteopontin in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS)
    • Braitch M, Constantinescu CS. The role of osteopontin in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). Inflamm Allergy Drug Targets (2010) 9(4):249-56. doi:10.2174/187152810793358778
    • (2010) Inflamm Allergy Drug Targets , vol.9 , Issue.4 , pp. 249-256
    • Braitch, M.1    Constantinescu, C.S.2
  • 13
    • 84867344577 scopus 로고    scopus 로고
    • The impact of osteopontin gene variations on multiple sclerosis development and progression
    • Comi C, Cappellano G, Chiocchetti A, Orilieri E, Buttini S, Ghezzi L, et al. The impact of osteopontin gene variations on multiple sclerosis development and progression. Clin Dev Immunol (2012) 2012:212893. doi:10.1155/2012/212893
    • (2012) Clin Dev Immunol , vol.2012
    • Comi, C.1    Cappellano, G.2    Chiocchetti, A.3    Orilieri, E.4    Buttini, S.5    Ghezzi, L.6
  • 14
    • 0033579511 scopus 로고    scopus 로고
    • The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin
    • Yokosaki Y, Matsuura N, Sasaki T, Murakami I, Schneider H, Higashiyama S, et al. The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem (1999) 274(51):36328-34. doi:10.1074/jbc.274.51.36328
    • (1999) J Biol Chem , vol.274 , Issue.51 , pp. 36328-36334
    • Yokosaki, Y.1    Matsuura, N.2    Sasaki, T.3    Murakami, I.4    Schneider, H.5    Higashiyama, S.6
  • 15
    • 71849086031 scopus 로고    scopus 로고
    • Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis
    • Murugaiyan G, Mittal A, Weiner HL. Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis. J Immunol (2008) 181(11):7480-8. doi:10.4049/jimmunol.181.11.7480
    • (2008) J Immunol , vol.181 , Issue.11 , pp. 7480-7488
    • Murugaiyan, G.1    Mittal, A.2    Weiner, H.L.3
  • 16
    • 84876582298 scopus 로고    scopus 로고
    • N-terminal rather than full-length osteopontin orits C-terminal fragment is associated with carotid-plaque inflammation inhypertensive patients
    • Wolak T, Sion-Vardi N, Novack V, Greenberg G, Szendro G, Tarnovscki T, et al. N-terminal rather than full-length osteopontin orits C-terminal fragment is associated with carotid-plaque inflammation inhypertensive patients. Am J Hypertens (2013) 26(3):326-33. doi:10.1093/ajh/hps043
    • (2013) Am J Hypertens , vol.26 , Issue.3 , pp. 326-333
    • Wolak, T.1    Sion-Vardi, N.2    Novack, V.3    Greenberg, G.4    Szendro, G.5    Tarnovscki, T.6
  • 17
    • 84979790726 scopus 로고    scopus 로고
    • Thrombin cleavage of osteopontin modulates its activities in human cells in vitro and mouse experimental autoimmune encephalomyelitis in vivo
    • Boggio E, Dianzani C, Gigliotti CL, Soluri MF, Clemente N, Cappellano G, et al. Thrombin cleavage of osteopontin modulates its activities in human cells in vitro and mouse experimental autoimmune encephalomyelitis in vivo. J Immunol Res (2016) 2016:9345495. doi:10.1155/2016/9345495
    • (2016) J Immunol Res , vol.2016
    • Boggio, E.1    Dianzani, C.2    Gigliotti, C.L.3    Soluri, M.F.4    Clemente, N.5    Cappellano, G.6
  • 18
    • 33846998653 scopus 로고    scopus 로고
    • Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
    • Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol (2007) 8(1):74-83. doi:10.1038/ni1415
    • (2007) Nat Immunol , vol.8 , Issue.1 , pp. 74-83
    • Hur, E.M.1    Youssef, S.2    Haws, M.E.3    Zhang, S.Y.4    Sobel, R.A.5    Steinman, L.6
  • 19
    • 84867352357 scopus 로고    scopus 로고
    • Response to comment on "the influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease"
    • Steinman L, Youssef S, Van Venrooij N, Chabas D, Baranzini SE, Rittling S, et al. Response to comment on "the influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease". Science (2003) 299(5614):1845. doi:10.1126/science.1080223
    • (2003) Science , vol.299 , Issue.5614 , pp. 1845
    • Steinman, L.1    Youssef, S.2    Van Venrooij, N.3    Chabas, D.4    Baranzini, S.E.5    Rittling, S.6
  • 20
    • 0034930681 scopus 로고    scopus 로고
    • Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis
    • Sakata M, Tsuruha JI, Masuko-Hongo K, Nakamura H, Matsui T, Sudo A, et al. Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis. J Rheumatol (2001) 28(7):1492-5
    • (2001) J Rheumatol , vol.28 , Issue.7 , pp. 1492-1495
    • Sakata, M.1    Tsuruha, J.I.2    Masuko-Hongo, K.3    Nakamura, H.4    Matsui, T.5    Sudo, A.6
  • 21
    • 47249145601 scopus 로고    scopus 로고
    • Treatment of collagen-induced arthritis with ananti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells
    • Fan K, Dai J, Wang H, Wei H, Cao Z, Hou S, et al. Treatment of collagen-induced arthritis with ananti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells. Arthritis Rheum (2008) 58(7):2041-52. doi:10.1002/art.23490
    • (2008) Arthritis Rheum , vol.58 , Issue.7 , pp. 2041-2052
    • Fan, K.1    Dai, J.2    Wang, H.3    Wei, H.4    Cao, Z.5    Hou, S.6
  • 23
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol (2001) 50(1):121-7. doi:10.1002/ana.1032
    • (2001) Ann Neurol , vol.50 , Issue.1 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3    Goodkin, D.4    Hartung, H.P.5    Lublin, F.D.6
  • 24
    • 46749123864 scopus 로고    scopus 로고
    • Factors predicting incomplete recovery from relapses in multiple sclerosis: a prospective study
    • Leone MA, Bonissoni S, Collimedaglia L, Tesser F, Calzoni S, Stecco A, et al. Factors predicting incomplete recovery from relapses in multiple sclerosis: a prospective study. Mult Scler (2008) 14(4):485-93. doi:10.1177/1352458507084650
    • (2008) Mult Scler , vol.14 , Issue.4 , pp. 485-493
    • Leone, M.A.1    Bonissoni, S.2    Collimedaglia, L.3    Tesser, F.4    Calzoni, S.5    Stecco, A.6
  • 25
    • 20144387016 scopus 로고    scopus 로고
    • Multiple sclerosis severity score: using disability and disease duration torate disease severity
    • Roxburgh RH, Seaman SR, Masterman T, Hensiek AE, Sawcer SJ, Vukusic S, et al. Multiple sclerosis severity score: using disability and disease duration torate disease severity. Neurology (2005) 64(7):1144-51. doi:10.1212/01.WNL.0000156155.19270.F8
    • (2005) Neurology , vol.64 , Issue.7 , pp. 1144-1151
    • Roxburgh, R.H.1    Seaman, S.R.2    Masterman, T.3    Hensiek, A.E.4    Sawcer, S.J.5    Vukusic, S.6
  • 26
    • 33751243318 scopus 로고    scopus 로고
    • Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis
    • Uyttenhove C, Van Snick J. Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis. Eur J Immunol (2006) 36(11):2868-74. doi:10.1002/eji.200636662
    • (2006) Eur J Immunol , vol.36 , Issue.11 , pp. 2868-2874
    • Uyttenhove, C.1    Van Snick, J.2
  • 27
    • 84908401417 scopus 로고    scopus 로고
    • Subcutaneous inverse vaccination with PLGA particles loaded with a MOG peptide and IL-10 decreases the severity of experimental autoimmune encephalomyelitis
    • Cappellano G, Woldetsadik AD, Orilieri E, Shivakumar Y, Rizzi M, Carniato F, et al. Subcutaneous inverse vaccination with PLGA particles loaded with a MOG peptide and IL-10 decreases the severity of experimental autoimmune encephalomyelitis. Vaccine (2014) 32(43):5681-9. doi:10.1016/j.vaccine.2014.08.016
    • (2014) Vaccine , vol.32 , Issue.43 , pp. 5681-5689
    • Cappellano, G.1    Woldetsadik, A.D.2    Orilieri, E.3    Shivakumar, Y.4    Rizzi, M.5    Carniato, F.6
  • 28
    • 0033987925 scopus 로고    scopus 로고
    • Exploiting recombination in single bacteria to make large phage antibody libraries
    • Sblattero D, Bradbury A. Exploiting recombination in single bacteria to make large phage antibody libraries. Nat Biotechnol (2000) 18(1):75-80. doi:10.1038/71958
    • (2000) Nat Biotechnol , vol.18 , Issue.1 , pp. 75-80
    • Sblattero, D.1    Bradbury, A.2
  • 29
    • 34548402959 scopus 로고    scopus 로고
    • Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models
    • Di Niro R, Ziller F, Florian F, Crovella S, Stebel M, Bestagno M, et al. Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models. BMC Biotechnol (2007) 7:46. doi:10.1186/1472-6750-7-46
    • (2007) BMC Biotechnol , vol.7 , pp. 46
    • Di Niro, R.1    Ziller, F.2    Florian, F.3    Crovella, S.4    Stebel, M.5    Bestagno, M.6
  • 30
    • 84963542806 scopus 로고    scopus 로고
    • Therapeutic strategies targeting B-cells in multiple sclerosis
    • Milo R. Therapeutic strategies targeting B-cells in multiple sclerosis. Autoimmun Rev (2016) 15(7):714-8. doi:10.1016/j.autrev.2016.03.006
    • (2016) Autoimmun Rev , vol.15 , Issue.7 , pp. 714-718
    • Milo, R.1
  • 31
    • 84896070550 scopus 로고    scopus 로고
    • Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial
    • Kappos L, Hartung HP, Freedman MS, Boyko A, Radü EW, Mikol DD, et al. Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial. Lancet Neurol (2014) 13(4):353-63. doi:10.1016/S1474-4422(14)70028-6
    • (2014) Lancet Neurol , vol.13 , Issue.4 , pp. 353-363
    • Kappos, L.1    Hartung, H.P.2    Freedman, M.S.3    Boyko, A.4    Radü, E.W.5    Mikol, D.D.6
  • 32
    • 84926408540 scopus 로고    scopus 로고
    • ATON: results from a phase II randomized trial of the B-cell-targeting agent atacicept in patients with optic neuritis
    • Sergott RC, Bennett JL, Rieckmann P, Montalban X, Mikol D, Freudensprung U, et al. ATON: results from a phase II randomized trial of the B-cell-targeting agent atacicept in patients with optic neuritis. J Neurol Sci (2015) 351(1-2):174-8. doi:10.1016/j.jns.2015.02.019
    • (2015) J Neurol Sci , vol.351 , Issue.1-2 , pp. 174-178
    • Sergott, R.C.1    Bennett, J.L.2    Rieckmann, P.3    Montalban, X.4    Mikol, D.5    Freudensprung, U.6
  • 33
    • 40749132997 scopus 로고    scopus 로고
    • Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritis
    • Nestorov I, Munafo A, Papasouliotis O, Visich J. Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritis. J Clin Pharmacol (2008) 48(4):406-17. doi:10.1177/0091270008315312
    • (2008) J Clin Pharmacol , vol.48 , Issue.4 , pp. 406-417
    • Nestorov, I.1    Munafo, A.2    Papasouliotis, O.3    Visich, J.4
  • 34
    • 84888873502 scopus 로고    scopus 로고
    • The improvement of cognitive functions is associated with a decrease of plasma osteopontin levels in natalizumab treated relapsing multiple sclerosis
    • Iaffaldano P, Ruggieri M, Viterbo RG, Mastrapasqua M, Trojano M. The improvement of cognitive functions is associated with a decrease of plasma osteopontin levels in natalizumab treated relapsing multiple sclerosis. Brain Behav Immun (2014) 35:96-101. doi:10.1016/j.bbi.2013.08.009
    • (2014) Brain Behav Immun , vol.35 , pp. 96-101
    • Iaffaldano, P.1    Ruggieri, M.2    Viterbo, R.G.3    Mastrapasqua, M.4    Trojano, M.5
  • 35
    • 84884813611 scopus 로고    scopus 로고
    • Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica
    • Shimizu Y, Ota K, Ikeguchi R, Kubo S, Kabasawa C, Uchiyama S. Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica. J Neuroimmunol (2013) 263(1-2):148-51. doi:10.1016/j.jneuroim.2013.07.005
    • (2013) J Neuroimmunol , vol.263 , Issue.1-2 , pp. 148-151
    • Shimizu, Y.1    Ota, K.2    Ikeguchi, R.3    Kubo, S.4    Kabasawa, C.5    Uchiyama, S.6
  • 36
    • 84896123714 scopus 로고    scopus 로고
    • Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development
    • Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, et al. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler (2014) 20(4):438-44. doi:10.1177/1352458513503052
    • (2014) Mult Scler , vol.20 , Issue.4 , pp. 438-444
    • Kivisäkk, P.1    Healy, B.C.2    Francois, K.3    Gandhi, R.4    Gholipour, T.5    Egorova, S.6
  • 37
    • 84910115061 scopus 로고    scopus 로고
    • No evidence for an association of osteopontin plasma levels with disease activity in multiple sclerosis
    • Runia TF, van Meurs M, Nasserinejad K, Hintzen RQ. No evidence for an association of osteopontin plasma levels with disease activity in multiple sclerosis. Mult Scler (2014) 20(12):1670-1. doi:10.1177/1352458514528765
    • (2014) Mult Scler , vol.20 , Issue.12 , pp. 1670-1671
    • Runia, T.F.1    van Meurs, M.2    Nasserinejad, K.3    Hintzen, R.Q.4
  • 38
    • 79959536193 scopus 로고    scopus 로고
    • CD44 reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis
    • Guan H, Nagarkatti PS, Nagarkatti M. CD44 reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis. J Immunol (2011) 186(12):6955-64. doi:10.4049/jimmunol.1004043
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 6955-6964
    • Guan, H.1    Nagarkatti, P.S.2    Nagarkatti, M.3
  • 39
    • 84866896574 scopus 로고    scopus 로고
    • Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis
    • Winkler CW, Foster SC, Matsumoto SG, Preston MA, Xing R, Bebo BF, et al. Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis. J Biol Chem (2012) 287(40):33237-51. doi:10.1074/jbc.M112.356287
    • (2012) J Biol Chem , vol.287 , Issue.40 , pp. 33237-33251
    • Winkler, C.W.1    Foster, S.C.2    Matsumoto, S.G.3    Preston, M.A.4    Xing, R.5    Bebo, B.F.6
  • 40
    • 84875190575 scopus 로고    scopus 로고
    • CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: a role in immune cells and vascular cells of the blood-brain barrier
    • Flynn KM, Michaud M, Madri JA. CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: a role in immune cells and vascular cells of the blood-brain barrier. Am J Pathol (2013) 182(4):1322-36. doi:10.1016/j.ajpath.2013.01.003
    • (2013) Am J Pathol , vol.182 , Issue.4 , pp. 1322-1336
    • Flynn, K.M.1    Michaud, M.2    Madri, J.A.3
  • 41
    • 84874566273 scopus 로고    scopus 로고
    • Overexpression of CD44 in neural precursor cells improves trans-endothelial migration and facilitates their invasion of perivascular tissues in vivo
    • Deboux C, Ladraa S, Cazaubon S, Ghribi-Mallah S, Weiss N, Chaverot N, et al. Overexpression of CD44 in neural precursor cells improves trans-endothelial migration and facilitates their invasion of perivascular tissues in vivo. PLoS One (2013) 8(2):e57430. doi:10.1371/journal.pone.0057430
    • (2013) PLoS One , vol.8 , Issue.2
    • Deboux, C.1    Ladraa, S.2    Cazaubon, S.3    Ghribi-Mallah, S.4    Weiss, N.5    Chaverot, N.6
  • 42
    • 84883312632 scopus 로고    scopus 로고
    • CD44 variant isoforms control experimental autoimmune encephalomyelitis by affecting the lifespan of the pathogenic T cells
    • Ghazi-Visser L, Laman JD, Nagel S, van Meurs M, van Riel D, Tzankov A, et al. CD44 variant isoforms control experimental autoimmune encephalomyelitis by affecting the lifespan of the pathogenic T cells. FASEB J (2013) 27(9):3683-701. doi:10.1096/fj.13-228809
    • (2013) FASEB J , vol.27 , Issue.9 , pp. 3683-3701
    • Ghazi-Visser, L.1    Laman, J.D.2    Nagel, S.3    van Meurs, M.4    van Riel, D.5    Tzankov, A.6
  • 43
    • 84870253612 scopus 로고    scopus 로고
    • The role of T cell apoptosis in nervous system autoimmunity
    • Comi C, Fleetwood T, Dianzani U. The role of T cell apoptosis in nervous system autoimmunity. Autoimmun Rev (2012) 12(2):150-6. doi:10.1016/j.autrev.2011.08.011
    • (2012) Autoimmun Rev , vol.12 , Issue.2 , pp. 150-156
    • Comi, C.1    Fleetwood, T.2    Dianzani, U.3
  • 44
    • 57049166456 scopus 로고    scopus 로고
    • Osteopontin: role in immune regulation and stress responses
    • Wang KX, Denhardt DT. Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev (2008) 19(5-6):333-45. doi:10.1016/j.cytogfr.2008.08.001
    • (2008) Cytokine Growth Factor Rev , vol.19 , Issue.5-6 , pp. 333-345
    • Wang, K.X.1    Denhardt, D.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.