ATON: Results from a Phase II randomized trial of the B-cell-targeting agent atacicept in patients with optic neuritis

Journal of the Neurological Sciences

Volumn 351, Issue 1-2, 2015, Pages 174-178

  Sergott, Robert C ^a   Bennett, Jeffrey L ^b   Rieckmann, Peter ^c   Montalban, Xavier ^d   Mikol, Daniel ^e   Freudensprung, Ulrich ^f   Plitz, Thomas ^f   Van Beek, Johan ^f  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Sozialstiftung Bamberg Hospital   (Germany)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^e EMD SERONO INC   (United States)

^f MERCK KGAA   (Germany)

Author keywords

Atacicept; Clinically definite multiple sclerosis; Multiple sclerosis; Optic neuritis; Optical coherence tomography; Retinal nerve fiber layer

Indexed keywords

ATACICEPT; HYBRID PROTEIN; TACI RECEPTOR-IGG FC FRAGMENT FUSION PROTEIN;

ADULT; ARTICLE; BLISTER; CHRONIC PYELONEPHRITIS; CLINICAL ARTICLE; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EYE DISEASE; FEMALE; FEVER; GASTROINTESTINAL DISEASE; HUMAN; INFECTION; INFESTATION; INJECTION SITE REACTION; INNER EAR DISEASE; MALE; MENTAL DISEASE; MULTICENTER STUDY (TOPIC); MULTIPLE SCLEROSIS; MUSCULOSKELETAL DISEASE; MYELITIS; NEUROLOGIC DISEASE; OPTIC NEURITIS; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RETINAL NERVE FIBER LAYER THICKNESS; SKIN DISEASE; TREATMENT DURATION; B LYMPHOCYTE; CHEMICALLY INDUCED; CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; NERVE FIBER; OPTICAL COHERENCE TOMOGRAPHY; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RETINA NERVE CELL; TREATMENT OUTCOME; ULTRASTRUCTURE;

ADULT; B-LYMPHOCYTES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NERVE FIBERS; OPTIC NEURITIS; RECOMBINANT FUSION PROTEINS; RETINAL NEURONS; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME;

EID: 84926408540     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2015.02.019     Document Type: Article

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