Mutation and catastrophe in the aging genome

Experimental Gerontology

Volumn 94, Issue , 2017, Pages 34-40

  Milholland, Brandon ^a   Suh, Yousin ^a   Vijg, Jan ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Aging; Catastrophe; Genomics; Somatic mutation; Translation error; Two hit model

Indexed keywords

AGING; ARTICLE; CATASTROPHE THEORY; DNA REPAIR; DNA REPLICATION; FEEDBACK SYSTEM; GENE MUTATION; GENE REGULATORY NETWORK; GENOMIC INSTABILITY; GENOMICS; HUMAN; MORTALITY; MUTATION ACCUMULATION; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SOMATIC MUTATION; THEORY; ADOLESCENT; ADULT; AGE; AGED; ANIMAL; BIOLOGICAL MODEL; CHILD; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; INFANT; METABOLISM; MIDDLE AGED; MUTATION; NEWBORN; PHYSIOLOGICAL FEEDBACK; PRESCHOOL CHILD; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ANIMALS; CHILD; CHILD, PRESCHOOL; DNA REPAIR; DNA REPLICATION; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; INFANT; INFANT, NEWBORN; MIDDLE AGED; MODELS, GENETIC; MUTATION; MUTATION RATE; YOUNG ADULT;

EID: 85016476904     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2017.02.073     Document Type: Article

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