Effect of Ku80 deficiency on mutation frequencies and spectra at a lacZ reporter locus in mouse tissues and cells

PLoS ONE

Volumn 3, Issue 10, 2008, Pages

  Busuttil, Rita A ^a,g   Muñoz, Denise P ^a   Garcia, Ana Maria ^b   Rodier, Francis ^c   Kim, Woo Ho ^d   Suh, Yousin ^e   Hasty, Paul ^f   Campisi, Judith ^a,c   Vijg, Jan ^a,e  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d Seoul National University   (South Korea)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^g PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BLEOMYCIN; CELL PROTEIN; HISTONE H2AX; HYDROGEN PEROXIDE; KU ANTIGEN; PROTEIN BP1; PROTEIN KU80; UNCLASSIFIED DRUG; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL STIMULATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; FIBROBLAST CULTURE; GENE MUTATION; GENE REARRANGEMENT; IN VITRO STUDY; IN VIVO STUDY; LIVER PARENCHYMA; MOUSE; MOUSE MUTANT; MUTATION RATE; MUTATIONAL ANALYSIS; NEWBORN; NONHUMAN; POINT MUTATION; PREMATURE AGING; PROTEIN DEFICIENCY; REPORTER GENE; SPLEEN; WILD TYPE; ANIMAL; ANTIBODY SPECIFICITY; CELL CULTURE; DNA REPAIR; FIBROBLAST; GENETICS; GENOMIC INSTABILITY; KINETICS; LACTOSE OPERON; METABOLISM; MUTATION;

ANIMALIA; MUS;

AGING, PREMATURE; ANIMALS; ANTIGENS, NUCLEAR; CELLS, CULTURED; DNA REPAIR; DNA-BINDING PROTEINS; FIBROBLASTS; GENES, REPORTER; GENOMIC INSTABILITY; KINETICS; LAC OPERON; MICE; MICE, MUTANT STRAINS; MUTATION; ORGAN SPECIFICITY;

EID: 55149105227     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003458     Document Type: Article

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