Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery

ACS Nano

Volumn 11, Issue 3, 2017, Pages 2531-2544

  Li, Jiahe ^a,b   Wang, Wade ^a   He, Yanpu ^a,b   Li, Yingzhong ^a,b   Yan, Emily Z ^a,b   Zhang, Ketian ^a,b   Irvine, Darrell J ^a,b,c   Hammond, Paula T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

eIF4E; mRNA; nanoplex; nucleic acid delivery

Indexed keywords

BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION; GENE TRANSFER; MOLECULAR BIOLOGY; RNA; STABILIZATION;

EUKARYOTIC INITIATION FACTOR; EUKARYOTIC INITIATION FACTOR 4E; MESSENGER RNA; NANOCARRIERS; NANOPLEX; NUCLEIC ACIDS DELIVERIES; PROTEIN SYNTHESIS; RIBONUCLEOPROTEINS; RNA TRANSLATION; TRANSFECTION EFFICIENCY;

PROTEINS;

CAPPED RNA; INITIATION FACTOR 4E; MESSENGER RNA; NANOPARTICLE;

CHEMISTRY; CONFORMATION; GENE TRANSFER; GENETICS; PROTEIN SYNTHESIS; TRANSLATION INITIATION;

EUKARYOTIC INITIATION FACTOR-4E; GENE TRANSFER TECHNIQUES; NANOPARTICLES; NUCLEIC ACID CONFORMATION; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROTEIN BIOSYNTHESIS; RNA CAPS; RNA, MESSENGER;

EID: 85016414588     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b08447     Document Type: Article

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