Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure

Journal of the American Chemical Society

Volumn 138, Issue 5, 2016, Pages 1478-1481

  Uchida, Hirokuni ^a   Itaka, Keiji ^a   Uchida, Satoshi ^a   Ishii, Takehiko ^b   Suma, Tomoya ^c   Miyata, Kanjiro ^a   Oba, Makoto ^d   Nishiyama, Nobuhiro ^e   Kataoka, Kazunori ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d NAGASAKI UNIVERSITY   (Japan)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINS; CHAINS; EFFICIENCY;

AMINOLYSIS REACTION; BINDING AFFINITIES; CRITICAL RESEARCHES; DELIVERY VEHICLE; EUKARYOTIC INITIATION FACTOR; IMMUNOPRECIPITATION ASSAYS; POTENTIAL UTILITY; TRANSLATIONAL EFFICIENCIES;

AMINES;

CAP BINDING PROTEIN; INITIATION FACTOR 4E; MESSENGER RNA; POLYAMINE; SPERMIDINE; SPERMINE; CAPPED RNA; PROTEIN BINDING;

5' UNTRANSLATED REGION; AMINOLYSIS; ARTICLE; CARTILAGE CELL; CELL FREE SYSTEM; COMPLEX FORMATION; CONTROLLED STUDY; IMMUNOGENICITY; IMMUNOPRECIPITATION; PROTEIN BINDING; PROTEIN POLYMERIZATION; PROTEIN SYNTHESIS; PROTON TRANSPORT; RNA TRANSLATION; TITRIMETRY; GENETICS; METABOLISM;

EUKARYOTIC INITIATION FACTOR-4E; POLYAMINES; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; RNA CAPS; RNA, MESSENGER;

EID: 84958211739     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b11726     Document Type: Article

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