Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

Cell Reports

Volumn 13, Issue 11, 2015, Pages 2456-2469

  del Pozo Martin, Yaiza ^a   Park, Danielle ^a   Ramachandran, Anassuya ^a   Ombrato, Luigi ^a   Calvo, Fernando ^b   Chakravarty, Probir ^a   Spencer Dene, Bradley ^a   Derzsi, Stefanie ^a   Hill, Caroline S ^a   Sahai, Erik ^a   Malanchi, Ilaria ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; PROTEIN AXL; PROTEIN TYROSINE KINASE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; THROMBOSPONDIN 2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; AXL RECEPTOR TYROSINE KINASE; CD24 ANTIGEN; FUSED ALICYCLIC AROMATIC COMPOUND; HOMEODOMAIN PROTEIN; ONCOPROTEIN; R428 COMPOUND; RAG-1 PROTEIN; SMAD PROTEIN; THROMBOSPONDIN; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL ACTIVATION; CELL INFILTRATION; CELL INTERACTION; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; LUNG FIBROBLAST; METASTASIS; METASTATIC INITIATING CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STROMA; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CANCER STEM CELL; CELL SURVIVAL; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; LUNG TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; RNA INTERFERENCE; SECONDARY; TRANSGENIC MOUSE; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; ANTIGENS, CD24; BENZOCYCLOHEPTENES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; MICE, TRANSGENIC; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD PROTEINS; THROMBOSPONDINS; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HETEROLOGOUS; TRIAZOLES;

EID: 84951310639     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.11.025     Document Type: Article

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