메뉴 건너뛰기




Volumn 8, Issue MAR, 2017, Pages

Cannabidiol reduces leukemic cell size - But is it important?

Author keywords

Cannabidiol; Cell size; Jurkat; Leukaemia; Physiological normoxia; Protein kinase B; Ribosomal protein S6

Indexed keywords

CANNABIDIOL; DOXORUBICIN; MAMMALIAN TARGET OF RAPAMYCIN; OXYGEN; PROTEIN KINASE B; PROTEIN S6;

EID: 85016149112     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2017.00144     Document Type: Article
Times cited : (30)

References (35)
  • 2
    • 33845863911 scopus 로고    scopus 로고
    • Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids
    • Börner, C., Höllt, V., Sebald, W., and Kraus, J. (2007). Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids. J. Leukoc. Biol. 81, 336-343. doi: 10.1189/jlb.0306224
    • (2007) J. Leukoc. Biol , vol.81 , pp. 336-343
    • Börner, C.1    Höllt, V.2    Sebald, W.3    Kraus, J.4
  • 4
    • 0030087688 scopus 로고    scopus 로고
    • Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation
    • Daaka, Y., Friedman, H., and Klein, T. W. (1996). Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation. J. Pharmacol. Exp. Ther. 276, 776-783.
    • (1996) J. Pharmacol. Exp. Ther , vol.276 , pp. 776-783
    • Daaka, Y.1    Friedman, H.2    Klein, T.W.3
  • 5
    • 84973547651 scopus 로고    scopus 로고
    • Safety and feasibility of fasting in combination with platinum-based chemotherapy
    • Dorff, T. B., Groshen, S., Garcia, A., Shah, M., Tsao-Wei, D., Pham, H., et al. (2016). Safety and feasibility of fasting in combination with platinum-based chemotherapy. BMC Cancer 16:360. doi: 10.1186/s12885-016-2370-6
    • (2016) BMC Cancer , vol.16 , pp. 360
    • Dorff, T.B.1    Groshen, S.2    Garcia, A.3    Shah, M.4    Tsao-Wei, D.5    Pham, H.6
  • 6
    • 0022468204 scopus 로고
    • Comparison of in vitro activity of cytotoxic drugs towards human carcinoma and leukaemia cell lines
    • Finlay, G. J., Wilson, W. R., and Baguley, B. C. (1986). Comparison of in vitro activity of cytotoxic drugs towards human carcinoma and leukaemia cell lines. Eur. J. Cancer Clin. Oncol. 22, 655-662. doi: 10.1016/0277-5379(86)90162-8
    • (1986) Eur. J. Cancer Clin. Oncol , vol.22 , pp. 655-662
    • Finlay, G.J.1    Wilson, W.R.2    Baguley, B.C.3
  • 7
    • 84938932680 scopus 로고    scopus 로고
    • Delta(9)-tetrahydrocannabinol and cannabidiol as potential curative agents for cancer: a critical examination of the preclinical literature
    • Fowler, C. J. (2015). Delta(9)-tetrahydrocannabinol and cannabidiol as potential curative agents for cancer: a critical examination of the preclinical literature. Clin. Pharmacol. Ther. 97, 587-596. doi: 10.1002/cpt.84
    • (2015) Clin. Pharmacol. Ther , vol.97 , pp. 587-596
    • Fowler, C.J.1
  • 8
    • 0037111475 scopus 로고    scopus 로고
    • Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors
    • Freeburn, R. W., Wright, K. L., Burgess, S. J., Astoul, E., Cantrell, D. A., and Ward, S. G. (2002). Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors. J. Immunol. 169, 5441-5450. doi: 10.4049/jimmunol.169.10.5441
    • (2002) J. Immunol , vol.169 , pp. 5441-5450
    • Freeburn, R.W.1    Wright, K.L.2    Burgess, S.J.3    Astoul, E.4    Cantrell, D.A.5    Ward, S.G.6
  • 9
    • 27144556646 scopus 로고    scopus 로고
    • Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis
    • Fumarola, C., La Monica, S., Alfieri, R. R., Borra, E., and Guidotti, G. G. (2005). Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis. Cell Death Discov. 12, 1344-1357. doi: 10.1038/sj.cdd.4401660
    • (2005) Cell Death Discov , vol.12 , pp. 1344-1357
    • Fumarola, C.1    La Monica, S.2    Alfieri, R.R.3    Borra, E.4    Guidotti, G.G.5
  • 10
    • 84881238904 scopus 로고    scopus 로고
    • Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells
    • Guo, C. W., Kawakatsu, M., Idemitsu, M., Urata, Y., Goto, S., Ono, Y., et al. (2013). Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells. J. Cell. Physiol. 228, 2159-2166. doi: 10.1002/jcp.24389
    • (2013) J. Cell. Physiol , vol.228 , pp. 2159-2166
    • Guo, C.W.1    Kawakatsu, M.2    Idemitsu, M.3    Urata, Y.4    Goto, S.5    Ono, Y.6
  • 11
    • 33744913027 scopus 로고    scopus 로고
    • The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
    • Herrera, B., Carracedo, A., Diez-Zaera, M., Gómez del Pulgar, T., Guzmán, M., and Velasco, G. (2006). The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. Exp. Cell Res. 312, 2121-2131. doi: 10.1016/j.yexcr.2006.03.009
    • (2006) Exp. Cell Res , vol.312 , pp. 2121-2131
    • Herrera, B.1    Carracedo, A.2    Diez-Zaera, M.3    Gómez del Pulgar, T.4    Guzmán, M.5    Velasco, G.6
  • 12
    • 24144455626 scopus 로고    scopus 로고
    • p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells
    • Herrera, B., Carracedo, A., Diez-Zaera, M., Guzmán, M., and Velasco, G. (2005). p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells. FEBS Lett. 579, 5084-5088. doi: 10.1016/j.febslet.2005.08.021
    • (2005) FEBS Lett , vol.579 , pp. 5084-5088
    • Herrera, B.1    Carracedo, A.2    Diez-Zaera, M.3    Guzmán, M.4    Velasco, G.5
  • 13
    • 84874647204 scopus 로고    scopus 로고
    • The genomic landscape of hypodiploid acute lymphoblastic leukemia
    • Holmfeldt, L., Wei, L., Diaz-Flores, E., Walsh, M., Zhang, J., Ding, L., et al. (2013). The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat. Genet. 45, 242-252. doi: 10.1038/ng.2532
    • (2013) Nat. Genet , vol.45 , pp. 242-252
    • Holmfeldt, L.1    Wei, L.2    Diaz-Flores, E.3    Walsh, M.4    Zhang, J.5    Ding, L.6
  • 14
    • 0034672605 scopus 로고    scopus 로고
    • Serum-dependent effects of tamoxifen and cannabinoids upon C6 glioma cell viability
    • Jacobsson, S. O., Rongård, E., Stridh, M., Tiger, G., and Fowler, C. J. (2000). Serum-dependent effects of tamoxifen and cannabinoids upon C6 glioma cell viability. Biochem. Pharmacol. 60, 1807-1813. doi: 10.1016/S0006-2952(00)00492-5
    • (2000) Biochem. Pharmacol , vol.60 , pp. 1807-1813
    • Jacobsson, S.O.1    Rongård, E.2    Stridh, M.3    Tiger, G.4    Fowler, C.J.5
  • 15
    • 33748417610 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria
    • Jia, W., Hegde, V. L., Singh, N. P., Sisco, D., Grant, S., Nagarkatti, M., et al. (2006). Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol. Cancer Res. 4, 549-562. doi: 10.1158/1541-7786.MCR-05-0193
    • (2006) Mol. Cancer Res , vol.4 , pp. 549-562
    • Jia, W.1    Hegde, V.L.2    Singh, N.P.3    Sisco, D.4    Grant, S.5    Nagarkatti, M.6
  • 16
    • 84862821594 scopus 로고    scopus 로고
    • Starvation, detoxification, and multidrug resistance in cancer therapy
    • Lee, C., Raffaghello, L., and Longo, V. D. (2012). Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resist. Updat. 15, 114-122. doi: 10.1016/j.drup.2012.01.004
    • (2012) Drug Resist. Updat , vol.15 , pp. 114-122
    • Lee, C.1    Raffaghello, L.2    Longo, V.D.3
  • 17
    • 20544444202 scopus 로고    scopus 로고
    • Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells
    • Lombard, C., Nagarkatti, M., and Nagarkatti, P. S. (2005). Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells. Leuk. Res. 29, 915-922. doi: 10.1016/j.leukres.2005.01.014
    • (2005) Leuk. Res , vol.29 , pp. 915-922
    • Lombard, C.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 18
    • 84902540119 scopus 로고    scopus 로고
    • Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol
    • Macpherson, T., Armstrong, J. A., Criddle, D. N., and Wright, K. L. (2014). Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol. In Vitro Cell Dev. Biol. Anim. 50, 417-426. doi: 10.1007/s11626-013-9719-9
    • (2014) In Vitro Cell Dev. Biol. Anim , vol.50 , pp. 417-426
    • Macpherson, T.1    Armstrong, J.A.2    Criddle, D.N.3    Wright, K.L.4
  • 19
    • 84872233704 scopus 로고    scopus 로고
    • Cannabidiol as potential anticancer drug
    • Massi, P., Solinas, M., Cinquina, V., and Parolaro, D. (2013). Cannabidiol as potential anticancer drug. Br. J. Clin. Pharmacol. 75, 303-312. doi: 10.1111/j.1365-2125.2012.04298.x
    • (2013) Br. J. Clin. Pharmacol , vol.75 , pp. 303-312
    • Massi, P.1    Solinas, M.2    Cinquina, V.3    Parolaro, D.4
  • 20
    • 84931003590 scopus 로고    scopus 로고
    • The antitumor activity of plant-derived non-psychoactive cannabinoids
    • McAllister, S. D., Soroceanu, L., and Desprez, P. Y. (2015). The antitumor activity of plant-derived non-psychoactive cannabinoids. J Neuroimmune Pharmacol. 10, 255-267. doi: 10.1007/s11481-015-9608-y
    • (2015) J Neuroimmune Pharmacol , vol.10 , pp. 255-267
    • McAllister, S.D.1    Soroceanu, L.2    Desprez, P.Y.3
  • 21
    • 33747592582 scopus 로고    scopus 로고
    • Cannabidiol-induced apoptosis in human leukemia cells: a novel role of cannabidiol in the regulation of p22phox and Nox4 expression
    • McKallip, R. J., Jia, W., Schlomer, J., Warren, J. W., Nagarkatti, P. S., and Nagarkatti, M. (2006). Cannabidiol-induced apoptosis in human leukemia cells: a novel role of cannabidiol in the regulation of p22phox and Nox4 expression. Mol. Pharmacol. 70, 897-908. doi: 10.1124/mol.106.023937
    • (2006) Mol. Pharmacol , vol.70 , pp. 897-908
    • McKallip, R.J.1    Jia, W.2    Schlomer, J.3    Warren, J.W.4    Nagarkatti, P.S.5    Nagarkatti, M.6
  • 22
    • 0037100312 scopus 로고    scopus 로고
    • Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
    • McKallip, R. J., Lombard, C., Fisher, M., Martin, B. R., Ryu, S., Grant, S., et al. (2002). Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100, 627-634. doi: 10.1182/blood-2002-01-0098
    • (2002) Blood , vol.100 , pp. 627-634
    • McKallip, R.J.1    Lombard, C.2    Fisher, M.3    Martin, B.R.4    Ryu, S.5    Grant, S.6
  • 23
    • 84930660341 scopus 로고    scopus 로고
    • Doxorubicin induces apoptosis in Jurkat cells by mitochondria-dependent and mitochondria-independent mechanisms under normoxic and hypoxic conditions
    • Mendivil-Perez, M., Velez-Pardo, C., and Jimenez-Del-Rio, M. (2015). Doxorubicin induces apoptosis in Jurkat cells by mitochondria-dependent and mitochondria-independent mechanisms under normoxic and hypoxic conditions. Anticancer Drugs 26, 583-598. doi: 10.1097/CAD.0000000000000223
    • (2015) Anticancer Drugs , vol.26 , pp. 583-598
    • Mendivil-Perez, M.1    Velez-Pardo, C.2    Jimenez-Del-Rio, M.3
  • 24
    • 0025120457 scopus 로고
    • The effects of pH and temperature on the in vitro bindings of delta-9-tetrahydrocannabinol and other cannabinoids to bovine serum albumin
    • Papa, V. M., Shen, M. L., and Ou, D. W. (1990). The effects of pH and temperature on the in vitro bindings of delta-9-tetrahydrocannabinol and other cannabinoids to bovine serum albumin. J. Pharm. Biomed. Anal. 8, 353-356. doi: 10.1016/0731-7085(90)80049-U
    • (1990) J. Pharm. Biomed. Anal , vol.8 , pp. 353-356
    • Papa, V.M.1    Shen, M.L.2    Ou, D.W.3
  • 25
    • 2342505872 scopus 로고    scopus 로고
    • Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells
    • Rao, G. K., Zhang, W., and Kaminski, N. E. (2004). Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells. J. Leukoc. Biol. 75, 884-892. doi: 10.1189/jlb.1203638
    • (2004) J. Leukoc. Biol , vol.75 , pp. 884-892
    • Rao, G.K.1    Zhang, W.2    Kaminski, N.E.3
  • 26
    • 33646195654 scopus 로고    scopus 로고
    • Force microscopy of nonadherent cells: a comparison of leukemia cell deformability
    • Rosenbluth, M. J., Lam, W. A., and Fletcher, D. A. (2006). Force microscopy of nonadherent cells: a comparison of leukemia cell deformability. Biophys. J. 90, 2994-3003. doi: 10.1529/biophysj.105.067496
    • (2006) Biophys. J , vol.90 , pp. 2994-3003
    • Rosenbluth, M.J.1    Lam, W.A.2    Fletcher, D.A.3
  • 27
    • 24944464482 scopus 로고    scopus 로고
    • Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis
    • Ruvinsky, I., Sharon, N., Lerer, T., Cohen, H., Stolovich-Rain, M., Nir, T., et al. (2005). Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. Genes Dev. 19, 2199-2211. doi: 10.1101/gad.351605
    • (2005) Genes Dev , vol.19 , pp. 2199-2211
    • Ruvinsky, I.1    Sharon, N.2    Lerer, T.3    Cohen, H.4    Stolovich-Rain, M.5    Nir, T.6
  • 28
    • 0345257345 scopus 로고    scopus 로고
    • The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway
    • Sancho, R., de la Vega, L., Appendino, G., Di Marzo, V., Macho, A., and Munoz, E. (2003). The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway. Br. J. Pharmacol. 140, 1035-1044. doi: 10.1038/sj.bjp.0705532
    • (2003) Br. J. Pharmacol , vol.140 , pp. 1035-1044
    • Sancho, R.1    de la Vega, L.2    Appendino, G.3    Di Marzo, V.4    Macho, A.5    Munoz, E.6
  • 29
    • 0038723739 scopus 로고    scopus 로고
    • Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1, possible involvement of lipid rafts
    • Sarker, K. P., and Maruyama, I. (2003). Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts. Cell Mol. Life Sci. 60, 1200-1208. doi: 10.1007/s00018-003-3055-2
    • (2003) Cell Mol. Life Sci , vol.60 , pp. 1200-1208
    • Sarker, K.P.1    Maruyama, I.2
  • 30
    • 0031062297 scopus 로고    scopus 로고
    • Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system
    • Schatz, A. R., Lee, M., Condie, R. B., Pulaski, J. T., and Kaminski, N. E. (1997). Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system. Toxicol. Appl. Pharmacol. 142, 278-287. doi: 10.1006/taap.1996.8034
    • (1997) Toxicol. Appl. Pharmacol , vol.142 , pp. 278-287
    • Schatz, A.R.1    Lee, M.2    Condie, R.B.3    Pulaski, J.T.4    Kaminski, N.E.5
  • 31
    • 0017702412 scopus 로고
    • Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
    • Schneider, U., Schwenk, H. U., and Bornkamm, G. (1977). Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int. J. Cancer 19, 621-626. doi: 10.1002/ijc.2910190505
    • (1977) Int. J. Cancer , vol.19 , pp. 621-626
    • Schneider, U.1    Schwenk, H.U.2    Bornkamm, G.3
  • 32
    • 0033811659 scopus 로고    scopus 로고
    • Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
    • Shan, X., Czar, M. J., Bunnell, S. C., Liu, P., Liu, Y., Schwartzberg, P. L., et al. (2000). Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol. Cell. Biol. 20, 6945-6957. doi: 10.1128/MCB.20.18.6945-6957.2000
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6945-6957
    • Shan, X.1    Czar, M.J.2    Bunnell, S.C.3    Liu, P.4    Liu, Y.5    Schwartzberg, P.L.6
  • 33
    • 79960115996 scopus 로고    scopus 로고
    • Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
    • Shrivastava, A., Kuzontkoski, P. M., Groopman, J. E., and Prasad, A. (2011). Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol. Cancer Ther. 10, 1161-1172. doi: 10.1158/1535-7163.MCT-10-1100
    • (2011) Mol. Cancer Ther , vol.10 , pp. 1161-1172
    • Shrivastava, A.1    Kuzontkoski, P.M.2    Groopman, J.E.3    Prasad, A.4
  • 34
    • 84892938475 scopus 로고    scopus 로고
    • Cannabis extract treatment for terminal acute lymphoblastic leukemia with a philadelphia chromosome mutation
    • Singh, Y., and Bali, C. (2013). Cannabis extract treatment for terminal acute lymphoblastic leukemia with a philadelphia chromosome mutation. Case Rep. Oncol. 6, 585-592. doi: 10.1159/000356446
    • (2013) Case Rep. Oncol , vol.6 , pp. 585-592
    • Singh, Y.1    Bali, C.2
  • 35
    • 0017098402 scopus 로고
    • Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol
    • Van Klingeren, B., and Ten Ham, M. (1976). Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol. Antonie Van Leeuwenhoek 42, 9-12. doi: 10.1007/BF00399444
    • (1976) Antonie Van Leeuwenhoek , vol.42 , pp. 9-12
    • Van Klingeren, B.1    Ten Ham, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.