메뉴 건너뛰기




Volumn 579, Issue 22, 2005, Pages 5084-5088

p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells

Author keywords

Apoptosis; Cannabinoids; CB2 receptor; p38 MAPK

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE; RIMONABANT; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

EID: 24144455626     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.08.021     Document Type: Article
Times cited : (73)

References (25)
  • 4
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • S. Munro, K.L. Thomas, and M. Abu-Shaar Molecular characterization of a peripheral receptor for cannabinoids Nature 365 1993 61 65
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 5
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • I. Galve-Roperh, C. Sanchez, M.L. Cortes, T.G. del Pulgar, M. Izquierdo, and M. Guzman Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation Nat. Med. 6 2000 313 319
    • (2000) Nat. Med. , vol.6 , pp. 313-319
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, M.L.3    Del Pulgar, T.G.4    Izquierdo, M.5    Guzman, M.6
  • 9
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • D. Piomelli The molecular logic of endocannabinoid signalling Nat. Rev. Neurosci. 4 2003 873 884
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 873-884
    • Piomelli, D.1
  • 10
    • 0142166330 scopus 로고    scopus 로고
    • Cannabinoids: Potential anticancer agents
    • M. Guzman Cannabinoids: potential anticancer agents Nat. Rev. Cancer 3 2003 745 755
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 745-755
    • Guzman, M.1
  • 14
    • 0035019372 scopus 로고    scopus 로고
    • Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus
    • P. Derkinderen, C. Ledent, M. Parmentier, and J.A. Girault Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus J. Neurochem. 77 2001 957 960
    • (2001) J. Neurochem. , vol.77 , pp. 957-960
    • Derkinderen, P.1    Ledent, C.2    Parmentier, M.3    Girault, J.A.4
  • 16
    • 0033806918 scopus 로고    scopus 로고
    • The CB(1) cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase
    • D. Rueda, I. Galve-Roperh, A. Haro, and M. Guzman The CB(1) cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase Mol. Pharmacol. 58 2000 814 820
    • (2000) Mol. Pharmacol. , vol.58 , pp. 814-820
    • Rueda, D.1    Galve-Roperh, I.2    Haro, A.3    Guzman, M.4
  • 17
    • 0034717184 scopus 로고    scopus 로고
    • Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells
    • O. Cuvillier, L. Edsall, and S. Spiegel Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells J. Biol. Chem. 275 2000 15691 15700
    • (2000) J. Biol. Chem. , vol.275 , pp. 15691-15700
    • Cuvillier, O.1    Edsall, L.2    Spiegel, S.3
  • 18
    • 0034284923 scopus 로고    scopus 로고
    • Aspirin induces apoptosis through mitochondrial cytochrome c release
    • M. Pique, M. Barragan, M. Dalmau, B. Bellosillo, G. Pons, and J. Gil Aspirin induces apoptosis through mitochondrial cytochrome c release FEBS Lett. 480 2000 193 196
    • (2000) FEBS Lett. , vol.480 , pp. 193-196
    • Pique, M.1    Barragan, M.2    Dalmau, M.3    Bellosillo, B.4    Pons, G.5    Gil, J.6
  • 19
    • 0033381793 scopus 로고    scopus 로고
    • 3-(1′,1′-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: Synthesis of selective ligands for the CB2 receptor
    • J.W. Huffman, J. Liddle, S. Yu, M.M. Aung, M.E. Abood, J.L. Wiley, and B.R. Martin 3-(1′,1′-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor Bioorg. Med. Chem. 7 1999 2905 2914
    • (1999) Bioorg. Med. Chem. , vol.7 , pp. 2905-2914
    • Huffman, J.W.1    Liddle, J.2    Yu, S.3    Aung, M.M.4    Abood, M.E.5    Wiley, J.L.6    Martin, B.R.7
  • 20
    • 2442502511 scopus 로고    scopus 로고
    • Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons
    • W.S. Choi, D.S. Eom, B.S. Han, W.K. Kim, B.H. Han, E.J. Choi, T.H. Oh, G.J. Markelonis, J.W. Cho, and Y.J. Oh Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons J. Biol. Chem. 279 2004 20451 20460
    • (2004) J. Biol. Chem. , vol.279 , pp. 20451-20460
    • Choi, W.S.1    Eom, D.S.2    Han, B.S.3    Kim, W.K.4    Han, B.H.5    Choi, E.J.6    Oh, T.H.7    Markelonis, G.J.8    Cho, J.W.9    Oh, Y.J.10
  • 21
    • 0036534724 scopus 로고    scopus 로고
    • De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis
    • T. Gomez del Pulgar, G. Velasco, C. Sanchez, A. Haro, and M. Guzman De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis Biochem. J. 363 2002 183 188
    • (2002) Biochem. J. , vol.363 , pp. 183-188
    • Gomez Del Pulgar, T.1    Velasco, G.2    Sanchez, C.3    Haro, A.4    Guzman, M.5
  • 22
    • 0142184948 scopus 로고    scopus 로고
    • Tetrahydrocannabinol-induced neurotoxicity depends on CB1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons
    • E.J. Downer, M.P. Fogarty, and V.A. Campbell Tetrahydrocannabinol-induced neurotoxicity depends on CB1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons Br. J. Pharmacol. 140 2003 547 557
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 547-557
    • Downer, E.J.1    Fogarty, M.P.2    Campbell, V.A.3
  • 23
    • 8844271735 scopus 로고    scopus 로고
    • Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways
    • J. Gertsch, R. Schoop, U. Kuenzle, and A. Suter Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways FEBS Lett. 577 2004 563 569
    • (2004) FEBS Lett. , vol.577 , pp. 563-569
    • Gertsch, J.1    Schoop, R.2    Kuenzle, U.3    Suter, A.4
  • 24
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • S. Kumar, J. Boehm, and J.C. Lee p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases Nat. Rev. Drug Discov. 2 2003 717 726
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 25
    • 4043179097 scopus 로고    scopus 로고
    • Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: Novel role for endogenous and exogenous cannabinoids in immunoregulation
    • Y. Do, R.J. McKallip, M. Nagarkatti, and P.S. Nagarkatti Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation J. Immunol. 173 2004 2373 2382
    • (2004) J. Immunol. , vol.173 , pp. 2373-2382
    • Do, Y.1    McKallip, R.J.2    Nagarkatti, M.3    Nagarkatti, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.