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Volumn 542, Issue 7639, 2017, Pages 49-54

The role of fatty acid β-oxidation in lymphangiogenesis

(33)  Wong, Brian W a,b   Wang, Xingwu a,b   Zecchin, Annalisa a,b   Thienpont, Bernard b,c   Cornelissen, Ivo a,b   Kalucka, Joanna a,b   García Caballero, Melissa d   Missiaen, Rindert a,b   Huang, Hongling a,b   Brüning, Ulrike a,b   Blacher, Silvia d   Vinckier, Stefan a,b   Goveia, Jermaine a,b   Knobloch, Marlen e   Zhao, Hui b,c   Dierkes, Cathrin f   Shi, Chenyan a,b   Hägerling, René f   Moral Dardé, Veronica a,b   Wyns, Sabine a,b   more..


Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; CARNITINE PALMITOYLTRANSFERASE 1A; CARNITINE PALMITOYLTRANSFERASE I; CRE RECOMBINASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PROX1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3; ACETIC ACID DERIVATIVE; CARNITINE PALMITOYLTRANSFERASE; CPT1B PROTEIN, MOUSE; FATTY ACID; HISTONE; HOMEODOMAIN PROTEIN; PROSPERO-RELATED HOMEOBOX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 85016143129     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21028     Document Type: Article
Times cited : (253)

References (47)
  • 1
    • 84867045079 scopus 로고    scopus 로고
    • Lymphangiogenesis and cancer
    • Christiansen, A. & Detmar, M. Lymphangiogenesis and cancer. Genes Cancer 2, 1146-1158 (2011).
    • (2011) Genes Cancer , vol.2 , pp. 1146-1158
    • Christiansen, A.1    Detmar, M.2
  • 2
    • 84862648524 scopus 로고    scopus 로고
    • Regulation and implications of inflammatory lymphangiogenesis
    • Kim, H., Kataru, R. P. & Koh, G. Y. Regulation and implications of inflammatory lymphangiogenesis. Trends Immunol. 33, 350-356 (2012).
    • (2012) Trends Immunol. , vol.33 , pp. 350-356
    • Kim, H.1    Kataru, R.P.2    Koh, G.Y.3
  • 3
    • 81255188905 scopus 로고    scopus 로고
    • The lymphatic vasculature in disease
    • Alitalo, K. The lymphatic vasculature in disease. Nat. Med. 17, 1371-1380 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 1371-1380
    • Alitalo, K.1
  • 4
    • 84904173553 scopus 로고    scopus 로고
    • Metabolism of stromal and immune cells in health and disease
    • Ghesquiere, B., et al. Metabolism of stromal and immune cells in health and disease. Nature 511, 167-176 (2014).
    • (2014) Nature , vol.511 , pp. 167-176
    • Ghesquiere, B.1
  • 5
    • 18544386859 scopus 로고    scopus 로고
    • Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
    • Petrova, T. V. et al. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J. 21, 4593-4599 (2002).
    • (2002) EMBO J. , vol.21 , pp. 4593-4599
    • Petrova, T.V.1
  • 6
    • 0037007216 scopus 로고    scopus 로고
    • An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
    • Wigle, J. T. et al. An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. EMBO J. 21, 1505-1513 (2002).
    • (2002) EMBO J. , vol.21 , pp. 1505-1513
    • Wigle, J.T.1
  • 7
    • 84896746916 scopus 로고    scopus 로고
    • Development of the mammalian lymphatic vasculature
    • Yang, Y. & Oliver, G. Development of the mammalian lymphatic vasculature. J. Clin. Invest. 124, 888-897 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 888-897
    • Yang, Y.1    Oliver, G.2
  • 8
    • 84877901574 scopus 로고    scopus 로고
    • COUP-TFII orchestrates venous and lymphatic endothelial identity by homo-or hetero-dimerisation with PROX1
    • Aranguren, X. L. et al. COUP-TFII orchestrates venous and lymphatic endothelial identity by homo-or hetero-dimerisation with PROX1. J. Cell Sci. 126, 1164-1175 (2013).
    • (2013) J. Cell Sci. , vol.126 , pp. 1164-1175
    • Aranguren, X.L.1
  • 9
    • 34948856826 scopus 로고    scopus 로고
    • Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
    • Srinivasan, R. S. et al. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21, 2422-2432 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 2422-2432
    • Srinivasan, R.S.1
  • 10
    • 84907494392 scopus 로고    scopus 로고
    • The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors
    • Srinivasan, R. S. et al. The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors. Genes Dev. 28, 2175-2187 (2014).
    • (2014) Genes Dev. , vol.28 , pp. 2175-2187
    • Srinivasan, R.S.1
  • 11
    • 84927563455 scopus 로고    scopus 로고
    • Fatty acid carbon is essential for dNTP synthesis in endothelial cells
    • Schoors, S. et al. Fatty acid carbon is essential for dNTP synthesis in endothelial cells. Nature 520, 192-197 (2015).
    • (2015) Nature , vol.520 , pp. 192-197
    • Schoors, S.1
  • 12
    • 9144236286 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
    • Karkkainen, M. J. et al. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 5, 74-80 (2004).
    • (2004) Nat. Immunol. , vol.5 , pp. 74-80
    • Karkkainen, M.J.1
  • 13
    • 84875217017 scopus 로고    scopus 로고
    • A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy
    • Hagerling, R. et al. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J. 32, 629-644 (2013).
    • (2013) EMBO J. , vol.32 , pp. 629-644
    • Hagerling, R.1
  • 14
    • 79960983746 scopus 로고    scopus 로고
    • Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice
    • Bazigou, E. et al. Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice. J. Clin. Invest. 121, 2984-2992 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 2984-2992
    • Bazigou, E.1
  • 15
    • 77951847278 scopus 로고    scopus 로고
    • Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development
    • Lin, F. J. et al. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J. Clin. Invest. 120, 1694-1707 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 1694-1707
    • Lin, F.J.1
  • 16
    • 40949156610 scopus 로고    scopus 로고
    • Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos
    • Hirashima, M. et al. Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev. Biol. 316, 149-159 (2008).
    • (2008) Dev. Biol. , vol.316 , pp. 149-159
    • Hirashima, M.1
  • 17
    • 70349306570 scopus 로고    scopus 로고
    • Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85a, p55a, and p50a
    • Mouta-Bellum, C. et al. Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85a , p55a , and p50a . Dev. Dyn. 238, 2670-2679 (2009).
    • (2009) Dev. Dyn. , vol.238 , pp. 2670-2679
    • Mouta-Bellum, C.1
  • 18
    • 84938642590 scopus 로고    scopus 로고
    • CKit lineage hemogenic endothelium-derived cells contribute to mesenteric lymphatic vessels
    • Rep. S2211-1247(15)00172-2
    • Stanczuk, L. et al. cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels. Cell Rep. S2211-1247(15)00172-2 (2015).
    • (2015) Cell
    • Stanczuk, L.1
  • 19
    • 0036840138 scopus 로고    scopus 로고
    • Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate
    • Hong, Y. K. et al. Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev. Dyn. 225, 351-357 (2002).
    • (2002) Dev. Dyn. , vol.225 , pp. 351-357
    • Hong, Y.K.1
  • 20
    • 57749087100 scopus 로고    scopus 로고
    • Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity
    • Johnson, N. C. et al. Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev. 22, 3282-3291 (2008).
    • (2008) Genes Dev. , vol.22 , pp. 3282-3291
    • Johnson, N.C.1
  • 21
    • 84871274937 scopus 로고    scopus 로고
    • Ras/MAPK signaling modulates VEGFR-3 expression through Ets-mediated p300 recruitment and histone acetylation on the Vegfr3 gene in lymphatic endothelial cells
    • Ichise, T., Yoshida, N. & Ichise, H. Ras/MAPK signaling modulates VEGFR-3 expression through Ets-mediated p300 recruitment and histone acetylation on the Vegfr3 gene in lymphatic endothelial cells. PLoS One 7, e51639 (2012).
    • (2012) PLoS One , vol.7 , pp. e51639
    • Ichise, T.1    Yoshida, N.2    Ichise, H.3
  • 22
    • 33947651613 scopus 로고    scopus 로고
    • Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis
    • Goldman, J. et al. Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis. FASEB J. 21, 1003-1012 (2007).
    • (2007) FASEB J. , vol.21 , pp. 1003-1012
    • Goldman, J.1
  • 23
    • 84903739739 scopus 로고    scopus 로고
    • Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains
    • Hay, D. A. et al. Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains. J. Am. Chem. Soc. 136, 9308-9319 (2014).
    • (2014) J. Am. Chem. Soc. , vol.136 , pp. 9308-9319
    • Hay, D.A.1
  • 24
    • 84905816638 scopus 로고    scopus 로고
    • Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation
    • Lee, J. V. et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metab. 20, 306-319 (2014).
    • (2014) Cell Metab. , vol.20 , pp. 306-319
    • Lee, J.V.1
  • 25
    • 84883242404 scopus 로고    scopus 로고
    • Differences in specificity and selectivity between CBP and p300 acetylation of histone H3 and H3/H4
    • Henry, R. A., Kuo, Y. M. & Andrews, A. J. Differences in specificity and selectivity between CBP and p300 acetylation of histone H3 and H3/H4. Biochemistry 52, 5746-5759 (2013).
    • (2013) Biochemistry , vol.52 , pp. 5746-5759
    • Henry, R.A.1    Kuo, Y.M.2    Andrews, A.J.3
  • 26
    • 84908616466 scopus 로고    scopus 로고
    • Posttranslational modifications of human histone H3: An update
    • Xu, Y. M., Du, J. Y. & Lau, A. T. Posttranslational modifications of human histone H3: an update. Proteomics 14, 2047-2060 (2014).
    • (2014) Proteomics , vol.14 , pp. 2047-2060
    • Xu, Y.M.1    Du, J.Y.2    Lau, A.T.3
  • 27
    • 2942668041 scopus 로고    scopus 로고
    • Lymphatic vasculature: Development, molecular regulation and role in tumor metastasis and inflammation
    • Saharinen, P., Tammela, T., Karkkainen, M. J. & Alitalo, K. Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends Immunol. 25, 387-395 (2004).
    • (2004) Trends Immunol. , vol.25 , pp. 387-395
    • Saharinen, P.1    Tammela, T.2    Karkkainen, M.J.3    Alitalo, K.4
  • 28
    • 84877116642 scopus 로고    scopus 로고
    • Sunitinib inhibits inflammatory corneal lymphangiogenesis
    • Detry, B. et al. Sunitinib inhibits inflammatory corneal lymphangiogenesis. Invest. Ophthalmol. Vis. Sci. 54, 3082-3093 (2013).
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , pp. 3082-3093
    • Detry, B.1
  • 29
    • 66249105703 scopus 로고    scopus 로고
    • ATP-citrate lyase links cellular metabolism to histone acetylation
    • Wellen, K. E. et al. ATP-citrate lyase links cellular metabolism to histone acetylation. Science 324, 1076-1080 (2009).
    • (2009) Science , vol.324 , pp. 1076-1080
    • Wellen, K.E.1
  • 30
    • 84894568529 scopus 로고    scopus 로고
    • Lymphangiogenesis and lymphatic vessel remodelling in cancer
    • Stacker, S. A. et al. Lymphangiogenesis and lymphatic vessel remodelling in cancer. Nat. Rev. Cancer 14, 159-172 (2014).
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 159-172
    • Stacker, S.A.1
  • 31
    • 68349105030 scopus 로고    scopus 로고
    • Integrin-a 9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis
    • Bazigou, E. et al. Integrin-a 9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev. Cell 17, 175-186 (2009).
    • (2009) Dev. Cell , vol.17 , pp. 175-186
    • Bazigou, E.1
  • 32
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe, E. A., Nachman, R. L., Becker, C. G. & Minick, C. R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52, 2745-2756 (1973).
    • (1973) J. Clin. Invest. , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 33
    • 0035903330 scopus 로고    scopus 로고
    • Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages
    • Kriehuber, E. et al. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J. Exp. Med. 194, 797-808 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 797-808
    • Kriehuber, E.1
  • 34
    • 3142512610 scopus 로고    scopus 로고
    • Targeting the tumor and its microenvironment by a dual-function decoy Met receptor
    • Michieli, P. et al. Targeting the tumor and its microenvironment by a dual-function decoy Met receptor. Cancer Cell 6, 61-73 (2004).
    • (2004) Cancer Cell , vol.6 , pp. 61-73
    • Michieli, P.1
  • 35
    • 1342311444 scopus 로고    scopus 로고
    • Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes
    • Carlotti, F. et al. Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes. Mol. Ther. 9, 209-217 (2004).
    • (2004) Mol. Ther. , vol.9 , pp. 209-217
    • Carlotti, F.1
  • 36
    • 2942716714 scopus 로고    scopus 로고
    • Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies
    • Korff, T., Krauss, T. & Augustin, H. G. Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies. Exp. Cell. Res. 297, 415-423 (2004).
    • (2004) Exp. Cell. Res. , vol.297 , pp. 415-423
    • Korff, T.1    Krauss, T.2    Augustin, H.G.3
  • 37
    • 67650409974 scopus 로고    scopus 로고
    • Additional parameters for the morphometry of angiogenesis and lymphangiogenesis in corneal flat mounts
    • Blacher, S., Detry, B., Bruyere, F., Foidart, J. M. & Noel, A. Additional parameters for the morphometry of angiogenesis and lymphangiogenesis in corneal flat mounts. Exp. Eye Res. 89, 274-276 (2009).
    • (2009) Exp. Eye Res. , vol.89 , pp. 274-276
    • Blacher, S.1    Detry, B.2    Bruyere, F.3    Foidart, J.M.4    Noel, A.5
  • 38
    • 53849146020 scopus 로고    scopus 로고
    • Model-based analysis of ChIP-Seq (MACS)
    • Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008).
    • (2008) Genome Biol. , vol.9 , pp. R137
    • Zhang, Y.1
  • 39
    • 77952857912 scopus 로고    scopus 로고
    • A signal-noise model for significance analysis of ChIP-seq with negative control
    • Xu, H. et al. A signal-noise model for significance analysis of ChIP-seq with negative control. Bioinformatics 26, 1199-1204 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 1199-1204
    • Xu, H.1
  • 40
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M.D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 41
    • 83455178287 scopus 로고    scopus 로고
    • SILEC: A protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards
    • Basu, S. S. & Blair, I. A. SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards. Nat. Protocols 7, 1-12 (2011).
    • (2011) Nat. Protocols , vol.7 , pp. 1-12
    • Basu, S.S.1    Blair, I.A.2
  • 42
    • 0030873452 scopus 로고    scopus 로고
    • Energy turnover of vascular endothelial cells
    • Culic, O., Gruwel, M. L. & Schrader, J. Energy turnover of vascular endothelial cells. Am. J. Physiol. 273, C205-C213 (1997).
    • (1997) Am. J. Physiol. , vol.273 , pp. C205-C213
    • Culic, O.1    Gruwel, M.L.2    Schrader, J.3
  • 43
    • 0242515803 scopus 로고    scopus 로고
    • What determines the intracellular ATP concentration
    • Ataullakhanov, F. I. & Vitvitsky, V. M. What determines the intracellular ATP concentration. Biosci. Rep. 22, 501-511 (2002).
    • (2002) Biosci. Rep. , vol.22 , pp. 501-511
    • Ataullakhanov, F.I.1    Vitvitsky, V.M.2
  • 44
    • 78649894468 scopus 로고    scopus 로고
    • Physiological levels of ATP negatively regulate proteasome function
    • Huang, H. et al. Physiological levels of ATP negatively regulate proteasome function. Cell Res. 20, 1372-1385 (2010).
    • (2010) Cell Res. , vol.20 , pp. 1372-1385
    • Huang, H.1
  • 45
    • 0014198718 scopus 로고
    • Adenosine triphosphate conservation in metabolic regulation. Rat liver citrate cleavage enzyme
    • Atkinson, D. E. & Walton, G. M. Adenosine triphosphate conservation in metabolic regulation. Rat liver citrate cleavage enzyme. J. Biol. Chem. 242, 3239-3241 (1967).
    • (1967) J. Biol. Chem. , vol.242 , pp. 3239-3241
    • Atkinson, D.E.1    Walton, G.M.2
  • 46
    • 38649143118 scopus 로고    scopus 로고
    • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
    • Aragones, J. et al. Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat. Genet. 40, 170-180 2008).
    • (2008) Nat. Genet. , vol.40 , pp. 170-180
    • Aragones, J.1
  • 47
    • 84899714028 scopus 로고    scopus 로고
    • Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events
    • McCloy, R. A. et al. Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events. Cell Cycle 13, 1400-1412 (2014).
    • (2014) Cell Cycle , vol.13 , pp. 1400-1412
    • McCloy, R.A.1


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