Inhibition of gap junction intercellular communication is involved in silica nanoparticles-induced H9c2 cardiomyocytes apoptosis via the mitochondrial pathway

International Journal of Nanomedicine

Volumn 12, Issue , 2017, Pages 2179-2188

  Du, Zhong Jun ^a   Cui, Guan Qun ^b   Zhang, Juan ^a   Liu, Xiao Mei ^c   Zhang, Zhi Hu ^a   Jia, Qiang ^a   Ng, Jack C ^d   Peng, Cheng ^a,d   Bo, Cun Xiang ^a   Shao, Hua ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^b QILU CHILDREN S HOSPITAL OF SHANDONG UNIVERSITY   (China)

^c JILIN UNIVERSITY   (China)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cardiotoxicity; Cell death; Connexin 43; Gap junction; Silica nanoparticles

Indexed keywords

CARBENOXOLONE; CASPASE 3; CASPASE 9; CONNEXIN 43; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; SILICA NANOPARTICLE; NANOPARTICLE; RETINOIC ACID; SILICON DIOXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIAC MUSCLE CELL; CARDIOTOXICITY; CELL COMMUNICATION; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; GAP JUNCTION; H9C2 CELL; HEART MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; SIGNAL TRANSDUCTION; TIME FACTOR; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CELL COMMUNICATION; CELL LINE; GAP JUNCTIONS; MITOCHONDRIA; MYOCYTES, CARDIAC; NANOPARTICLES; RATS; SIGNAL TRANSDUCTION; SILICON DIOXIDE; TIME FACTORS; TRETINOIN;

EID: 85016132806     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S127904     Document Type: Article

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