Cardiovascular toxicity of different sizes amorphous silica nanoparticles in rats after intratracheal instillation

Cardiovascular Toxicology

Volumn 13, Issue 3, 2013, Pages 194-207

  Du, Zhongjun ^a   Zhao, Dali ^a   Jing, Li ^b   Cui, Guanqun ^a   Jin, Minghua ^a   Li, Yang ^a   Liu, Xiaomei ^a   Liu, Ying ^a   Du, Haiying ^a   Guo, Caixia ^b   Zhou, Xianqing ^b   Sun, Zhiwei ^a,b  

^a JILIN UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cardiovascular toxicity; Endothelial dysfunction; Inflammatory reaction; Oxidative stress; Silica nanoparticles

Indexed keywords

C REACTIVE PROTEIN; CREATINE KINASE MB; D DIMER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MALONALDEHYDE; NANOPARTICLE; NITRIC OXIDE; PADGEM PROTEIN; REACTIVE OXYGEN METABOLITE; SILICA NANOPARTICLE; SILICON DIOXIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; CARDIOTOXICITY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ERYTHROCYTE COUNT; EXPOSURE; FLAME PHOTOMETRY; HEMOGLOBIN BLOOD LEVEL; HISTOPATHOLOGY; INFLAMMATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE COUNT; LUNG ALVEOLUS; LUNG CAPILLARY; MALE; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; THROMBOCYTE COUNT; TOXICITY TESTING;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; BIOLOGICAL MARKERS; BLOOD CELL COUNT; BLOOD COAGULATION; CARDIOVASCULAR DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; INDICATORS AND REAGENTS; INFLAMMATION MEDIATORS; INTUBATION, INTRATRACHEAL; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIUM; NANOPARTICLES; OXIDATIVE STRESS; PARTICLE SIZE; RATS; RATS, WISTAR; SILICON DIOXIDE;

EID: 84884292327     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-013-9198-y     Document Type: Article

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