메뉴 건너뛰기




Volumn 21, Issue 1, 2007, Pages 123-132

Increased bax/bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with Myasthenia gravis

Author keywords

Apoptosis; Bax Bcl 2 ratio; Caspase 3; Myasthenia gravis; Prognosis; Thymectomy

Indexed keywords

AZATHIOPRINE; CASPASE 3; MESSENGER RNA; PREDNISONE; PROTEIN BAX; PROTEIN BCL 2; PYRIDOSTIGMINE;

EID: 33847668419     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (311)

References (29)
  • 1
    • 0012107789 scopus 로고
    • Disorders of the neuromuscular junction
    • In: Rowland P (ed.). Baltimore, Williams and Wilkins
    • Penn AS and Rowland P: Disorders of the neuromuscular junction. In: Merritt's Textbook of Neurology. Rowland P (ed.). Baltimore, Williams and Wilkins, pp. 754-761, 1995.
    • (1995) Merritt's Textbook of Neurology , pp. 754-761
    • Penn, A.S.1    Rowland, P.2
  • 3
    • 0023701551 scopus 로고
    • Maximal thymectomy for myasthenia gravis
    • Jaretzki A and Wolff M: Maximal thymectomy for myasthenia gravis. J Thorac Cardiovasc Surg 96: 711-716, 1988.
    • (1988) J Thorac Cardiovasc Surg , vol.96 , pp. 711-716
    • Jaretzki, A.1    Wolff, M.2
  • 6
    • 0031048545 scopus 로고    scopus 로고
    • Bcl-2 and the ICE family of apoptotic regulators: Making a connection
    • Rao L and White E: Bcl-2 and the ICE family of apoptotic regulators: making a connection. Current Opin Genet Dev 7: 52-58, 1997.
    • (1997) Current Opin Genet Dev , vol.7 , pp. 52-58
    • Rao, L.1    White, E.2
  • 8
    • 0025231503 scopus 로고
    • Developmental biology of T cells in T cell-receptor transgenic mice
    • Von Boehmer H: Developmental biology of T cells in T cell-receptor transgenic mice. Annu Rev Immunol 8: 531-556, 1990.
    • (1990) Annu Rev Immunol , vol.8 , pp. 531-556
    • Von Boehmer, H.1
  • 9
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh CD and Sprent J: T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372: 100-103, 1994.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 10
    • 0033017328 scopus 로고    scopus 로고
    • Caspase inhibitors in prevention of apoptosis
    • Rudel T: Caspase inhibitors in prevention of apoptosis. Herz 24: 236-241, 1999.
    • (1999) Herz , vol.24 , pp. 236-241
    • Rudel, T.1
  • 11
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milligan C, Schreiber RD and Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 333-336, 1990.
    • (1990) Nature , vol.348 , pp. 333-336
    • Hockenbery, D.1    Nunez, G.2    Milligan, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 12
    • 0028325283 scopus 로고
    • The prevalence of bcl-2 immunoreactivity in breast carcinomas and its clinicopathological correlates, with particular reference to estrogen receptor status
    • Doglioni C, Dei Tos AP, Laurino L, Chiarelli C, Barbareschi M and Viale G: The prevalence of bcl-2 immunoreactivity in breast carcinomas and its clinicopathological correlates, with particular reference to estrogen receptor status. Virchows Archiv 424: 47-51, 1994.
    • (1994) Virchows Archiv , vol.424 , pp. 47-51
    • Doglioni, C.1    Dei Tos, A.P.2    Laurino, L.3    Chiarelli, C.4    Barbareschi, M.5    Viale, G.6
  • 14
    • 0035491323 scopus 로고    scopus 로고
    • The potential role of bcl-2, bax and Ki67 expression in thymus of patients with myasthenia gravis, and their correlation with clinicopathologic parameters
    • Salakou S, Tsamandas AC, Bonikos D, Papapetropoulos T and Dougenis D: The potential role of bcl-2, bax and Ki67 expression in thymus of patients with myasthenia gravis, and their correlation with clinicopathologic parameters. Eur J Cardiothoracic Sur 20: 712-721, 2001.
    • (2001) Eur J Cardiothoracic Sur , vol.20 , pp. 712-721
    • Salakou, S.1    Tsamandas, A.C.2    Bonikos, D.3    Papapetropoulos, T.4    Dougenis, D.5
  • 15
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conversed homolog, Bax, that accelerates programmed cell death
    • Oltvai Z, Milliman C and Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conversed homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619, 1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman, C.2    Korsmeyer, S.J.3
  • 16
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopics: A discourse on the BCL2 family and cell death
    • Yang E and Korsmeyer S: Molecular thanatopics: a discourse on the BCL2 family and cell death. Blood 88: 386-401, 1996.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.2
  • 17
    • 0033119372 scopus 로고    scopus 로고
    • Bcl-2 gene family and the regulation of programmed cell death
    • Korsmeyer SJ: Bcl-2 gene family and the regulation of programmed cell death. Cancer Res 59: S1693-S1700, 1999.
    • (1999) Cancer Res , vol.59
    • Korsmeyer, S.J.1
  • 22
    • 0034995263 scopus 로고    scopus 로고
    • Histologic typing of thymoma according to the New World Health Organization classification
    • Dadmanesh F, Sekihara T and Rosai J: Histologic typing of thymoma according to the New World Health Organization classification. Chest Surgery Clinics North America 11: 407-420, 2001.
    • (2001) Chest Surgery Clinics North America , vol.11 , pp. 407-420
    • Dadmanesh, F.1    Sekihara, T.2    Rosai, J.3
  • 23
    • 0034641222 scopus 로고    scopus 로고
    • Myasthenia gravis: Recommendation for clinical research standards
    • Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America
    • Jaretzki A, Barohn RB, Ernstoff R, Kaminski HR, Keesey JC, Penn AS and Sanders DB: Myasthenia gravis: recommendation for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America. Neurology 55: 16-23, 2000.
    • (2000) Neurology , vol.55 , pp. 16-23
    • Jaretzki, A.1    Barohn, R.B.2    Ernstoff, R.3    Kaminski, H.R.4    Keesey, J.C.5    Penn, A.S.6    Sanders, D.B.7
  • 24
    • 0028891851 scopus 로고
    • Expression of members of the bcl-2 family in the immature rat ovary: Equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis with decreased Bax and constitutive Bcl-2 and Bcl-xlong messenger ribonucleic acid levels
    • Tilly JL, Tilly KI, Kenton ML and Johnson AL: Expression of members of the bcl-2 family in the immature rat ovary: Equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis with decreased Bax and constitutive Bcl-2 and Bcl-xlong messenger ribonucleic acid levels. Endocrinology 136: 232-241, 1995.
    • (1995) Endocrinology , vol.136 , pp. 232-241
    • Tilly, J.L.1    Tilly, K.I.2    Kenton, M.L.3    Johnson, A.L.4
  • 26
    • 0030960657 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of expression of CPP32(caspase-3), a cell death protease
    • Krajewska M, Wang HG, Krajewski S, Zapata JM, Shabaik A, Gascoyne R and Reed JC: Immunohistochemical analysis of in vivo patterns of expression of CPP32(caspase-3), a cell death protease. Cancer Res 57: 1605-1613, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1605-1613
    • Krajewska, M.1    Wang, H.G.2    Krajewski, S.3    Zapata, J.M.4    Shabaik, A.5    Gascoyne, R.6    Reed, J.C.7
  • 27
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA and Yuan J: Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 403: 98-103, 2000.
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.