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Volumn 302, Issue 1, 2012, Pages 11-17

Uremic toxin p-cresol induces disassembly of gap junctions of cardiomyocytes

Author keywords

Cardiomyocyte; Connexin; Gap junction; P Cresol; Protein kinase C

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; CALCIUM; CONNEXIN 43; PARA CRESOL; PROTEIN KINASE C ALPHA; SMALL INTERFERING RNA; UREMIC TOXIN;

EID: 84865963424     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.07.004     Document Type: Article
Times cited : (47)

References (36)
  • 1
    • 11844254718 scopus 로고    scopus 로고
    • Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A
    • Ai X., Pogwizd S.M. Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A. Circ. Res. 2005, 96:54-63.
    • (2005) Circ. Res. , vol.96 , pp. 54-63
    • Ai, X.1    Pogwizd, S.M.2
  • 3
    • 0037085442 scopus 로고    scopus 로고
    • Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells
    • Boudreau R.T., Garduno R., Lin T.J. Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells. J. Biol. Chem. 2002, 277:5322-5329.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5322-5329
    • Boudreau, R.T.1    Garduno, R.2    Lin, T.J.3
  • 6
    • 45849084652 scopus 로고    scopus 로고
    • An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction
    • Chen K.H., Tung P.Y., Wu J.C., Chen Y., Chen P.C., Huang S.H., Wang S.M. An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction. Cancer Lett. 2008, 267:37-48.
    • (2008) Cancer Lett. , vol.267 , pp. 37-48
    • Chen, K.H.1    Tung, P.Y.2    Wu, J.C.3    Chen, Y.4    Chen, P.C.5    Huang, S.H.6    Wang, S.M.7
  • 7
    • 7444226471 scopus 로고    scopus 로고
    • 17Beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor
    • Chung T.H., Wang S.M., Wu J.C. 17Beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor. J. Mol. Cell. Cardiol. 2004, 37:1013-1022.
    • (2004) J. Mol. Cell. Cardiol. , vol.37 , pp. 1013-1022
    • Chung, T.H.1    Wang, S.M.2    Wu, J.C.3
  • 8
    • 0033621884 scopus 로고    scopus 로고
    • The epsilon subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation
    • Doble B.W., Ping P., Kardami E. The epsilon subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation. Circ. Res. 2000, 86:293-301.
    • (2000) Circ. Res. , vol.86 , pp. 293-301
    • Doble, B.W.1    Ping, P.2    Kardami, E.3
  • 11
    • 0024402489 scopus 로고
    • Factors affecting polyacrylamide gel electrophoresis and electroblotting of high-molecular-weight myofibrillar proteins
    • Fritz J.D., Swartz D.R., Greaser M.L. Factors affecting polyacrylamide gel electrophoresis and electroblotting of high-molecular-weight myofibrillar proteins. Anal. Biochem. 1989, 180:205-210.
    • (1989) Anal. Biochem. , vol.180 , pp. 205-210
    • Fritz, J.D.1    Swartz, D.R.2    Greaser, M.L.3
  • 12
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed
    • Gabriels J.E., Paul D.L. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ. Res. 1998, 83:636-643.
    • (1998) Circ. Res. , vol.83 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 13
    • 34250635347 scopus 로고    scopus 로고
    • Protein kinase C-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells
    • Guan L., Song K., Pysz M.A., Curry K.J., Hizli A.A., Danielpour D., Black A.R., Black J.D. Protein kinase C-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells. J. Biol. Chem. 2007, 282:14213-14225.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14213-14225
    • Guan, L.1    Song, K.2    Pysz, M.A.3    Curry, K.J.4    Hizli, A.A.5    Danielpour, D.6    Black, A.R.7    Black, J.D.8
  • 14
    • 4444256469 scopus 로고    scopus 로고
    • Mechanism of oleic acid-induced gap junctional disassembly in rat cardiomyocytes
    • Huang Y.S., Tseng Y.Z., Wu J.C., Wang S.M. Mechanism of oleic acid-induced gap junctional disassembly in rat cardiomyocytes. J. Mol. Cell. Cardiol 2004, 37:755-766.
    • (2004) J. Mol. Cell. Cardiol , vol.37 , pp. 755-766
    • Huang, Y.S.1    Tseng, Y.Z.2    Wu, J.C.3    Wang, S.M.4
  • 16
    • 73349090269 scopus 로고    scopus 로고
    • Biological and biophysical properties of vascular connexin channels
    • Johnstone S., Isakson B., Locke D. Biological and biophysical properties of vascular connexin channels. Int. Rev. Cell Mol. Biol. 2009, 278:69-118.
    • (2009) Int. Rev. Cell Mol. Biol. , vol.278 , pp. 69-118
    • Johnstone, S.1    Isakson, B.2    Locke, D.3
  • 17
    • 0034812869 scopus 로고    scopus 로고
    • The role of myocardial gap junctions in electrical conduction and arrhythmogenesis
    • Kanno S., Saffitz J.E. The role of myocardial gap junctions in electrical conduction and arrhythmogenesis. Cardiovasc. Pathol. 2001, 10:169-177.
    • (2001) Cardiovasc. Pathol. , vol.10 , pp. 169-177
    • Kanno, S.1    Saffitz, J.E.2
  • 18
    • 20444369494 scopus 로고    scopus 로고
    • Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation
    • Laird D.W. Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation. Biochim. Biophys. Acta 2005, 1711:172-182.
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 172-182
    • Laird, D.W.1
  • 19
    • 0034671950 scopus 로고    scopus 로고
    • Regulation of gap junctions by phosphorylation of connexins
    • Lampe P.D., Lau A.F. Regulation of gap junctions by phosphorylation of connexins. Arch. Biochem. Biophys. 2000, 384:205-215.
    • (2000) Arch. Biochem. Biophys. , vol.384 , pp. 205-215
    • Lampe, P.D.1    Lau, A.F.2
  • 20
    • 1942470517 scopus 로고    scopus 로고
    • The effects of connexin phosphorylation on gap junctional communication
    • Lampe P.D., Lau A.F. The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 2004, 36:1171-1186.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1171-1186
    • Lampe, P.D.1    Lau, A.F.2
  • 21
    • 77954786480 scopus 로고    scopus 로고
    • Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?
    • Lekawanvijit S., Adrahtas A., Kelly D.J., Kompa A.R., Wang B.H., Krum H. Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?. Eur. Heart J. 2010, 31:1771-1779.
    • (2010) Eur. Heart J. , vol.31 , pp. 1771-1779
    • Lekawanvijit, S.1    Adrahtas, A.2    Kelly, D.J.3    Kompa, A.R.4    Wang, B.H.5    Krum, H.6
  • 22
    • 0034076871 scopus 로고    scopus 로고
    • Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions
    • Li W.E., Nagy J.I. Activation of fibres in rat sciatic nerve alters phosphorylation state of connexin-43 at astrocytic gap junctions in spinal cord: evidence for junction regulation by neuronal-glial interactions. Neuroscience 2000, 97:113-123.
    • (2000) Neuroscience , vol.97 , pp. 113-123
    • Li, W.E.1    Nagy, J.I.2
  • 23
    • 0035088123 scopus 로고    scopus 로고
    • Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C
    • Mackay K., Mochly-Rosen D. Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C. Cardiovasc. Res 2001, 50:65-74.
    • (2001) Cardiovasc. Res , vol.50 , pp. 65-74
    • Mackay, K.1    Mochly-Rosen, D.2
  • 25
    • 0025789648 scopus 로고
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
    • Musil L.S., Goodenough D.A. Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J. Cell Biol. 1991, 115:1357-1374.
    • (1991) J. Cell Biol. , vol.115 , pp. 1357-1374
    • Musil, L.S.1    Goodenough, D.A.2
  • 27
    • 31844445153 scopus 로고    scopus 로고
    • Quantitative determination of gap junction intercellular communication by scrape loading and image analysis
    • Opsahl H., Rivedal E. Quantitative determination of gap junction intercellular communication by scrape loading and image analysis. Cell Adhes. Commun. 2000, 7:367-375.
    • (2000) Cell Adhes. Commun. , vol.7 , pp. 367-375
    • Opsahl, H.1    Rivedal, E.2
  • 28
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Sohl G., Willecke K. Gap junctions and the connexin protein family. Cardiovasc. Res. 2004, 62:228-232.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 228-232
    • Sohl, G.1    Willecke, K.2
  • 29
    • 0037672632 scopus 로고    scopus 로고
    • Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation
    • Solan J.L., Fry M.D., TenBroek E.M., Lampe P.D. Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation. J. Cell Sci. 2003, 116:2203-2211.
    • (2003) J. Cell Sci. , vol.116 , pp. 2203-2211
    • Solan, J.L.1    Fry, M.D.2    TenBroek, E.M.3    Lampe, P.D.4
  • 30
    • 20444411484 scopus 로고    scopus 로고
    • Connexin phosphorylation as a regulatory event linked to gap junction channel assembly
    • Solan J.L., Lampe P.D. Connexin phosphorylation as a regulatory event linked to gap junction channel assembly. Biochim. Biophys. Acta 2005, 1711:154-163.
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 154-163
    • Solan, J.L.1    Lampe, P.D.2
  • 31
    • 64249170988 scopus 로고    scopus 로고
    • Connexin43 phosphorylation: structural changes and biological effects
    • Solan J.L., Lampe P.D. Connexin43 phosphorylation: structural changes and biological effects. Biochem. J. 2009, 419:261-272.
    • (2009) Biochem. J. , vol.419 , pp. 261-272
    • Solan, J.L.1    Lampe, P.D.2
  • 32
    • 80051916439 scopus 로고    scopus 로고
    • Cellular chemosensitivity assays: an overview
    • Sumantran V.N. Cellular chemosensitivity assays: an overview. Methods Mol. Biol. 2011, 731:219-236.
    • (2011) Methods Mol. Biol. , vol.731 , pp. 219-236
    • Sumantran, V.N.1
  • 35
    • 0032189511 scopus 로고    scopus 로고
    • Role of M-line proteins in sarcomeric titin assembly during cardiac myofibrillogenesis
    • Wang S.M., Lo M.C., Shang C., Kao S.C., Tseng Y.Z. Role of M-line proteins in sarcomeric titin assembly during cardiac myofibrillogenesis. J. Cell. Biochem. 1998, 71:82-95.
    • (1998) J. Cell. Biochem. , vol.71 , pp. 82-95
    • Wang, S.M.1    Lo, M.C.2    Shang, C.3    Kao, S.C.4    Tseng, Y.Z.5
  • 36
    • 80052170947 scopus 로고    scopus 로고
    • A uremic solute, p-cresol, inhibits the proliferation of endothelial progenitor cells via the p38 pathway
    • Ying Y., Yang K., Liu Y., Chen Q.J., Shen W.F., Lu L., Zhang R.Y. A uremic solute, p-cresol, inhibits the proliferation of endothelial progenitor cells via the p38 pathway. Circ. J. 2011, 75:2252-2259.
    • (2011) Circ. J. , vol.75 , pp. 2252-2259
    • Ying, Y.1    Yang, K.2    Liu, Y.3    Chen, Q.J.4    Shen, W.F.5    Lu, L.6    Zhang, R.Y.7


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