Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Yu, Yang ^a   Li, Yang ^b   Wang, Wen ^b   Jin, Minghua ^b   Du, Zhongjun ^b   Li, Yanbo ^a   Duan, Junchao ^a   Yu, Yongbo ^a   Sun, Zhiwei ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE; NANOPARTICLE; SILICON DIOXIDE; SILICON DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CAPILLARY ENDOTHELIUM; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GRANULOMATOSIS; HISTOLOGY; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; KIDNEY; LACTATE DEHYDROGENASE BLOOD LEVEL; LD 50; LIVER; LIVER CELL; LIVER CELL DAMAGE; LUNG; LUNG DISEASE; LUNG INTERSTITIUM; LUNG INTERSTITIUM THICKENING; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MEGAKARYOCYTE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PNEUMONIA; SPLEEN; SPLEEN DISEASE; TOXICITY TESTING; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BODY WEIGHT; HYDRODYNAMICS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; LETHAL DOSE 50; MICE; MICE, INBRED ICR; NANOPARTICLES; ORGAN SPECIFICITY; PARTICLE SIZE; SILICON; SILICON DIOXIDE; SPECTROPHOTOMETRY, ATOMIC; STATIC ELECTRICITY; TISSUE DISTRIBUTION; TOXICITY TESTS, ACUTE;

MUS;

EID: 84876096177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061346     Document Type: Article

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