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Volumn 21, Issue 6, 2015, Pages 1219-1228

Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: A systematic review

Author keywords

Crohn's disease; dysbiosis; microbiome; microbiota

Indexed keywords

BUTYRIC ACID; CASPASE RECRUITMENT DOMAIN PROTEIN 15; SHORT CHAIN FATTY ACID;

EID: 84929857413     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000382     Document Type: Article
Times cited : (195)

References (90)
  • 1
    • 48249156638 scopus 로고    scopus 로고
    • What is the role of the metabolic activity of the gut microbiota in inflammatory bowel disease? Probing for answers with stable isotopes
    • Barclay AR, Morrison DJ, Weaver LT. What is the role of the metabolic activity of the gut microbiota in inflammatory bowel disease? Probing for answers with stable isotopes. J Pediatr Gastroenterol Nutr. 2008;46:486-495.
    • (2008) J Pediatr Gastroenterol Nutr , vol.46 , pp. 486-495
    • Barclay, A.R.1    Morrison, D.J.2    Weaver, L.T.3
  • 2
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis of inflammatory bowel disease
    • Khor B, Gardet A, Xavier RJ. Genetics and pathogenesis of inflammatory bowel disease. Nature. 2011;474:307-317.
    • (2011) Nature , vol.474 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.J.3
  • 4
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635-1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 5
    • 84862276328 scopus 로고    scopus 로고
    • Structure function and diversity of the healthy human microbiome
    • Human Microbiome Project C. Structure, function and diversity of the healthy human microbiome. Nature. 2012;486:207-214.
    • (2012) Nature , vol.486 , pp. 207-214
    • Human Microbiome Project, C.1
  • 7
    • 79960854386 scopus 로고    scopus 로고
    • Intestinal microbiota in healthy adults: Temporal analysis reveals individual and common core and relation to intestinal symptoms
    • Jalanka-Tuovinen J, Salonen A, Nikkila J, et al. Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. PLoS One. 2011;6:e23035.
    • (2011) PLoS One , vol.6 , pp. e23035
    • Jalanka-Tuovinen, J.1    Salonen, A.2    Nikkila, J.3
  • 8
    • 84875904427 scopus 로고    scopus 로고
    • Long-term monitoring of the human intestinal microbiota composition
    • [published online ahead of print October 15]
    • Rajilic-Stojanovic M, Heilig HG, Tims S, et al. Long-term monitoring of the human intestinal microbiota composition. Environ Microbiol. [published online ahead of print October 15, 2012]. doi: 10.1111/1462-2920.12023.
    • (2012) Environ Microbiol
    • Rajilic-Stojanovic, M.1    Heilig, H.G.2    Tims, S.3
  • 10
    • 84881484788 scopus 로고    scopus 로고
    • Cohabiting family members share microbiota with one another and with their dogs
    • Song SJ, Lauber C, Costello EK, et al. Cohabiting family members share microbiota with one another and with their dogs. Elife. 2013;2:e00458.
    • (2013) Elife , vol.2 , pp. e00458
    • Song, S.J.1    Lauber, C.2    Costello, E.K.3
  • 11
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • Wu GD, Chen J, Hoffmann C, et al. Linking long-term dietary patterns with gut microbial enterotypes. Science. 2011;334:105-108.
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3
  • 12
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505:559-563.
    • (2014) Nature , vol.505 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3
  • 13
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen L, Huse S, Sogin ML, et al. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol. 2008;6:e280.
    • (2008) PLoS Biol , vol.6 , pp. e280
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3
  • 14
    • 84861331645 scopus 로고    scopus 로고
    • Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota
    • Benjamin JL, Hedin CR, Koutsoumpas A, et al. Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota. Inflamm Bowel Dis. 2012;18:1092-1100.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1092-1100
    • Benjamin, J.L.1    Hedin, C.R.2    Koutsoumpas, A.3
  • 15
    • 84875047451 scopus 로고    scopus 로고
    • Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans
    • Biedermann L, Zeitz J, Mwinyi J, et al. Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans. PLoS One. 2013;8:e59260.
    • (2013) PLoS One , vol.8 , pp. e59260
    • Biedermann, L.1    Zeitz, J.2    Mwinyi, J.3
  • 16
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh PJ, Ley RE, Mahowald MA, et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444: 1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3
  • 17
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins. Nature. 2009;457:480-484.
    • (2009) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 18
    • 84880059693 scopus 로고    scopus 로고
    • Dysbiosis signature of fecal microbiota in colorectal cancer patients
    • Wu N, Yang X, Zhang R, et al. Dysbiosis signature of fecal microbiota in colorectal cancer patients. Microb Ecol. 2013;66:462-470.
    • (2013) Microb Ecol , vol.66 , pp. 462-470
    • Wu, N.1    Yang, X.2    Zhang, R.3
  • 19
    • 84856534859 scopus 로고    scopus 로고
    • Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
    • Castellarin M, Warren RL, Freeman JD, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res. 2012; 22:299-306.
    • (2012) Genome Res , vol.22 , pp. 299-306
    • Castellarin, M.1    Warren, R.L.2    Freeman, J.D.3
  • 20
    • 84898824175 scopus 로고    scopus 로고
    • Interactions between the intestinal microbiome and liver diseases
    • Schnabl B, Brenner DA. Interactions between the intestinal microbiome and liver diseases. Gastroenterology. 2014;146:1513-1524.
    • (2014) Gastroenterology , vol.146 , pp. 1513-1524
    • Schnabl, B.1    Brenner, D.A.2
  • 21
    • 84868555218 scopus 로고    scopus 로고
    • The microbiota link to irritable bowel syndrome: An emerging story
    • Jeffery IB, Quigley EM, Ohman L, et al. The microbiota link to irritable bowel syndrome: an emerging story. Gut Microbes. 2012;3:572-576.
    • (2012) Gut Microbes , vol.3 , pp. 572-576
    • Jeffery, I.B.1    Quigley, E.M.2    Ohman, L.3
  • 22
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • Jeffery IB, O'Toole PW, Ohman L, et al. An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut. 2012;61:997-1006.
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O'Toole, P.W.2    Ohman, L.3
  • 23
    • 80054119513 scopus 로고    scopus 로고
    • Molecular analysis of the luminal-and mucosal-associated intestinal microbiota in diarrheapredominant irritable bowel syndrome
    • Carroll IM, Ringel-Kulka T, Keku TO, et al. Molecular analysis of the luminal-and mucosal-associated intestinal microbiota in diarrheapredominant irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2011;301:G799-G807.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , pp. G799-G807
    • Carroll, I.M.1    Ringel-Kulka, T.2    Keku, T.O.3
  • 24
    • 84896092821 scopus 로고    scopus 로고
    • The treatment-naive microbiome in new-onset Crohn's disease
    • Gevers D, Kugathasan S, Denson LA, et al. The treatment-naive microbiome in new-onset Crohn's disease. Cell Host Microbe. 2014;15: 382-392.
    • (2014) Cell Host Microbe , vol.15 , pp. 382-392
    • Gevers, D.1    Kugathasan, S.2    Denson, L.A.3
  • 25
    • 84866549438 scopus 로고    scopus 로고
    • Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
    • Morgan XC, Tickle TL, Sokol H, et al. Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biol. 2012;13:R79.
    • (2012) Genome Biol , vol.13 , pp. R79
    • Morgan, X.C.1    Tickle, T.L.2    Sokol, H.3
  • 26
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 2010;464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 27
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
    • Manichanh C, Rigottier-Gois L, Bonnaud E, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut. 2006;55:205-211.
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3
  • 28
    • 84908554334 scopus 로고    scopus 로고
    • Bacterial protein signals are associated with Crohn's disease
    • Juste C, Kreil DP, Beauvallet C, et al. Bacterial protein signals are associated with Crohn's disease. Gut. 2014.
    • (2014) Gut.
    • Juste, C.1    Kreil, D.P.2    Beauvallet, C.3
  • 29
    • 20244388832 scopus 로고    scopus 로고
    • Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: A randomized, double-blind, placebo-controlled trial
    • Rutgeerts P, Van Assche G, Vermeire S, et al. Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology. 2005;128:856-861.
    • (2005) Gastroenterology , vol.128 , pp. 856-861
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 30
    • 0029079279 scopus 로고
    • Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection
    • Rutgeerts P, Hiele M, Geboes K, et al. Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection. Gastroenterology. 1995;108:1617-1621.
    • (1995) Gastroenterology , vol.108 , pp. 1617-1621
    • Rutgeerts, P.1    Hiele, M.2    Geboes, K.3
  • 31
    • 0025887076 scopus 로고
    • Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum
    • Rutgeerts P, Goboes K, Peeters M, et al. Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum. Lancet. 1991; 338:771-774.
    • (1991) Lancet , vol.338 , pp. 771-774
    • Rutgeerts, P.1    Goboes, K.2    Peeters, M.3
  • 32
    • 84865494677 scopus 로고    scopus 로고
    • Systematic review: Faecal microbiota transplantation in the management of inflammatory bowel disease
    • Anderson JL, Edney RJ, Whelan K. Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease. Aliment Pharmacol Ther. 2012;36:503-516.
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 503-516
    • Anderson, J.L.1    Edney, R.J.2    Whelan, K.3
  • 33
    • 84890435364 scopus 로고    scopus 로고
    • Fecal microbiota transplantation: Facts and controversies
    • van Nood E, Speelman P, Nieuwdorp M, et al. Fecal microbiota transplantation: facts and controversies. Curr Opin Gastroenterol. 2014;30:34-39.
    • (2014) Curr Opin Gastroenterol , vol.30 , pp. 34-39
    • Van Nood, E.1    Speelman, P.2    Nieuwdorp, M.3
  • 34
    • 84898835480 scopus 로고    scopus 로고
    • Manipulation of the microbiota for treatment of IBS and IBD-Challenges and Controversies
    • Shanahan F, Quigley EM. Manipulation of the Microbiota for Treatment of IBS and IBD-Challenges and Controversies. Gastroenterology. 2014; 146:1554-1563.
    • (2014) Gastroenterology , vol.146 , pp. 1554-1563
    • Shanahan, F.1    Quigley, E.M.2
  • 35
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6:e1000097.
    • (2009) PLoS Med , vol.6 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 36
    • 84868336049 scopus 로고    scopus 로고
    • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    • Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491:119-124.
    • (2012) Nature , vol.491 , pp. 119-124
    • Jostins, L.1    Ripke, S.2    Weersma, R.K.3
  • 37
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 2001;411:603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 38
    • 0037180433 scopus 로고    scopus 로고
    • Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
    • Stappenbeck TS, Hooper LV, Gordon JI. Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci USA. 2002;99:15451-15455.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15451-15455
    • Stappenbeck, T.S.1    Hooper, L.V.2    Gordon, J.I.3
  • 39
    • 33847016160 scopus 로고    scopus 로고
    • NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives
    • Devlin SM, Yang H, Ippoliti A, et al. NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives. Gastroenterology. 2007;132:576-586.
    • (2007) Gastroenterology , vol.132 , pp. 576-586
    • Devlin, S.M.1    Yang, H.2    Ippoliti, A.3
  • 40
    • 34548153548 scopus 로고    scopus 로고
    • Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients
    • Papp M, Altorjay I, Norman GL, et al. Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients. Inflamm Bowel Dis. 2007;13:984-992.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 984-992
    • Papp, M.1    Altorjay, I.2    Norman, G.L.3
  • 41
    • 84861001724 scopus 로고    scopus 로고
    • Inflammatory bowel diseases phenotype C. Difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition
    • Li E, Hamm CM, Gulati AS, et al. Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition. PLoS One. 2012;7:e26284.
    • (2012) PLoS One , vol.7 , pp. e26284
    • Li, E.1    Hamm, C.M.2    Gulati, A.S.3
  • 42
    • 80052580369 scopus 로고    scopus 로고
    • Nod2 is essential for temporal development of intestinal microbial communities
    • Rehman A, Sina C, Gavrilova O, et al. Nod2 is essential for temporal development of intestinal microbial communities. Gut. 2011;60:1354-1362.
    • (2011) Gut , vol.60 , pp. 1354-1362
    • Rehman, A.1    Sina, C.2    Gavrilova, O.3
  • 43
    • 78650099360 scopus 로고    scopus 로고
    • Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases
    • Frank DN, Robertson CE, Hamm CM, et al. Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases. Inflamm Bowel Dis. 2011;17:179-184.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 179-184
    • Frank, D.N.1    Robertson, C.E.2    Hamm, C.M.3
  • 44
    • 84928259169 scopus 로고    scopus 로고
    • PWE-082 the impact of Nod2 variants on gut microbiota in Crohn's disease and healthy controls
    • Kennedy N, Walker A, Berry S, et al. PWE-082 the impact of Nod2 variants on gut microbiota in Crohn's disease and healthy controls. Gut. 2014;63(suppl 1):A159-A160.
    • (2014) Gut , vol.63 , pp. A159-A160
    • Kennedy, N.1    Walker, A.2    Berry, S.3
  • 45
    • 46749119859 scopus 로고    scopus 로고
    • Molecular analysis of the gut microbiota of identical twins with Crohn's disease
    • Dicksved J, Halfvarson J, Rosenquist M, et al. Molecular analysis of the gut microbiota of identical twins with Crohn's disease. ISME J. 2008;2: 716-727.
    • (2008) ISME J , vol.2 , pp. 716-727
    • Dicksved, J.1    Halfvarson, J.2    Rosenquist, M.3
  • 46
    • 66249129571 scopus 로고    scopus 로고
    • Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease
    • Willing B, Halfvarson J, Dicksved J, et al. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis. 2009;15:653-660.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 653-660
    • Willing, B.1    Halfvarson, J.2    Dicksved, J.3
  • 47
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • e1
    • Willing BP, Dicksved J, Halfvarson J, et al. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology. 2010; 139:1844-1854.e1.
    • (2010) Gastroenterology , vol.139 , pp. 1844-1854
    • Willing, B.P.1    Dicksved, J.2    Halfvarson, J.3
  • 48
    • 79953748870 scopus 로고    scopus 로고
    • Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
    • Joossens M, Huys G, Cnockaert M, et al. Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut. 2011;60:631-637.
    • (2011) Gut , vol.60 , pp. 631-637
    • Joossens, M.1    Huys, G.2    Cnockaert, M.3
  • 49
    • 84908507536 scopus 로고    scopus 로고
    • Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings
    • Hedin CR, McCarthy NE, Louis P, et al. Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings. Gut. 2014;63:1578-1586.
    • (2014) Gut , vol.63 , pp. 1578-1586
    • Hedin, C.R.1    McCarthy, N.E.2    Louis, P.3
  • 50
    • 84928264148 scopus 로고    scopus 로고
    • OC-051 siblings of Crohn's disease patients exhibit a biologically relevant dysbiosis in the mucosal microbial community: A 16s Rrna Gene Pyrosequencing Study
    • Hedin C, van der Gast C, Rogers G, et al. OC-051 siblings of Crohn's disease patients exhibit a biologically relevant dysbiosis in the mucosal microbial community: a 16s Rrna Gene Pyrosequencing Study. Gut. 2014; 63(suppl 1):A25.
    • (2014) Gut , vol.63 , pp. A25
    • Hedin, C.1    Van Der Gast, C.2    Rogers, G.3
  • 51
    • 84870824919 scopus 로고    scopus 로고
    • Microbiota of de-novo pediatric IBD: Increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis
    • Hansen R, Russell RK, Reiff C, et al. Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol. 2012;107: 1913-1922.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1913-1922
    • Hansen, R.1    Russell, R.K.2    Reiff, C.3
  • 52
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA. 2008; 105:16731-16736.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 53
    • 77955300097 scopus 로고    scopus 로고
    • Microbiota in pediatric inflammatory bowel disease
    • e1
    • Schwiertz A, Jacobi M, Frick JS, et al. Microbiota in pediatric inflammatory bowel disease. J Pediatr. 2010;157:240-244.e1.
    • (2010) J Pediatr , vol.157 , pp. 240-244
    • Schwiertz, A.1    Jacobi, M.2    Frick, J.S.3
  • 54
    • 84875612653 scopus 로고    scopus 로고
    • Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease
    • Fujimoto T, Imaeda H, Takahashi K, et al. Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease. J Gastroenterol Hepatol. 2012;28:613-619.
    • (2012) J Gastroenterol Hepatol , vol.28 , pp. 613-619
    • Fujimoto, T.1    Imaeda, H.2    Takahashi, K.3
  • 55
    • 84872791148 scopus 로고    scopus 로고
    • Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: A case-control study in India
    • Kabeerdoss J, Sankaran V, Pugazhendhi S, et al. Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case-control study in India. BMC Gastroenterol. 2013;13:20.
    • (2013) BMC Gastroenterol , vol.13 , pp. 20
    • Kabeerdoss, J.1    Sankaran, V.2    Pugazhendhi, S.3
  • 56
    • 84899627277 scopus 로고    scopus 로고
    • Mucosa-associated Faecalibacterium prausnitzii and Escherichia coli co-abundance can distinguish Irritable Bowel Syndrome and Inflammatory Bowel Disease phenotypes
    • Lopez-Siles M, Martinez-Medina M, Busquets D, et al. Mucosa-associated Faecalibacterium prausnitzii and Escherichia coli co-abundance can distinguish Irritable Bowel Syndrome and Inflammatory Bowel Disease phenotypes. Int J Med Microbiol. 2014;304:464-475.
    • (2014) Int J Med Microbiol , vol.304 , pp. 464-475
    • Lopez-Siles, M.1    Martinez-Medina, M.2    Busquets, D.3
  • 57
    • 84905482236 scopus 로고    scopus 로고
    • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
    • Haberman Y, Tickle TL, Dexheimer PJ, et al. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. J Clin Invest. 2014;124:3617-3633.
    • (2014) J Clin Invest , vol.124 , pp. 3617-3633
    • Haberman, Y.1    Tickle, T.L.2    Dexheimer, P.J.3
  • 58
    • 84929168026 scopus 로고    scopus 로고
    • Characterization of gut microbiota profiles by disease activity in patients with Crohn's disease using data mining analysis of terminal restriction fragment length polymorphisms
    • Andoh A, Kobayashi T, Kuzuoka H, et al. Characterization of gut microbiota profiles by disease activity in patients with Crohn's disease using data mining analysis of terminal restriction fragment length polymorphisms. Biomed Rep. 2014;2:370-373.
    • (2014) Biomed Rep , vol.2 , pp. 370-373
    • Andoh, A.1    Kobayashi, T.2    Kuzuoka, H.3
  • 59
    • 84886742916 scopus 로고    scopus 로고
    • Terminal-restriction fragment length polymorphism analysis of diversity of mucosa-associated microbiota in patients with Crohn's disease [Article in Chinese]
    • Ran WB, Ouyang Q, Shi W. Terminal-restriction fragment length polymorphism analysis of diversity of mucosa-associated microbiota in patients with Crohn's disease [Article in Chinese]. Zhonghua Yi Xue Za Zhi. 2013;93:2884-2889.
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , pp. 2884-2889
    • Ran, W.B.1    Ouyang, Q.2    Shi, W.3
  • 60
    • 84859789740 scopus 로고    scopus 로고
    • Alterations in diversity of the oral microbiome in pediatric inflammatory bowel disease
    • Docktor MJ, Paster BJ, Abramowicz S, et al. Alterations in diversity of the oral microbiome in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2012;18:935-942.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 935-942
    • Docktor, M.J.1    Paster, B.J.2    Abramowicz, S.3
  • 61
    • 84866463340 scopus 로고    scopus 로고
    • Microbial dysbiosis in pediatric patients with Crohn's disease
    • Kaakoush NO, Day AS, Huinao KD, et al. Microbial dysbiosis in pediatric patients with Crohn's disease. J Clin Microbiol. 2012;50: 3258-3266.
    • (2012) J Clin Microbiol , vol.50 , pp. 3258-3266
    • Kaakoush, N.O.1    Day, A.S.2    Huinao, K.D.3
  • 62
    • 79960228384 scopus 로고    scopus 로고
    • High prevalence of aggregative adherent Escherichia coli strains in the mucosa-associated microbiota of patients with inflammatory bowel diseases
    • Thomazini CM, Samegima DA, Rodrigues MA, et al. High prevalence of aggregative adherent Escherichia coli strains in the mucosa-associated microbiota of patients with inflammatory bowel diseases. Int J Med Microbiol. 2011;301:475-479.
    • (2011) Int J Med Microbiol , vol.301 , pp. 475-479
    • Thomazini, C.M.1    Samegima, D.A.2    Rodrigues, M.A.3
  • 63
    • 79959835543 scopus 로고    scopus 로고
    • Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn's disease using terminal restriction fragment length polymorphism analysis
    • Andoh A, Imaeda H, Aomatsu T, et al. Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn's disease using terminal restriction fragment length polymorphism analysis. J Gastroenterol. 2011;46:479-486.
    • (2011) J Gastroenterol , vol.46 , pp. 479-486
    • Andoh, A.1    Imaeda, H.2    Aomatsu, T.3
  • 64
    • 78650973052 scopus 로고    scopus 로고
    • High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
    • Walker AW, Sanderson JD, Churcher C, et al. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol. 2011;11:7.
    • (2011) BMC Microbiol , vol.11 , pp. 7
    • Walker, A.W.1    Sanderson, J.D.2    Churcher, C.3
  • 65
    • 78049501532 scopus 로고    scopus 로고
    • Real-time analysis of mucosal flora in patients with inflammatory bowel disease in India
    • Verma R, Verma AK, Ahuja V, et al. Real-time analysis of mucosal flora in patients with inflammatory bowel disease in India. J Clin Microbiol. 2010;48:4279-4282.
    • (2010) J Clin Microbiol , vol.48 , pp. 4279-4282
    • Verma, R.1    Verma, A.K.2    Ahuja, V.3
  • 66
    • 78649622569 scopus 로고    scopus 로고
    • Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray
    • Kang S, Denman SE, Morrison M, et al. Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray. Inflamm Bowel Dis. 2010;16:2034-2042.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 2034-2042
    • Kang, S.1    Denman, S.E.2    Morrison, M.3
  • 67
    • 74249101114 scopus 로고    scopus 로고
    • Mucosal bacterial microflora and mucus layer thickness in adolescents with inflammatory bowel disease
    • Fyderek K, Strus M, Kowalska-Duplaga K, et al. Mucosal bacterial microflora and mucus layer thickness in adolescents with inflammatory bowel disease. World J Gastroenterol. 2009;15:5287-5294.
    • (2009) World J Gastroenterol , vol.15 , pp. 5287-5294
    • Fyderek, K.1    Strus, M.2    Kowalska-Duplaga, K.3
  • 68
    • 57649179488 scopus 로고    scopus 로고
    • Faecal microbiota profile of Crohn's disease determined by terminal restriction fragment length polymorphism analysis
    • Andoh A, Tsujikawa T, Sasaki M, et al. Faecal microbiota profile of Crohn's disease determined by terminal restriction fragment length polymorphism analysis. Aliment Pharmacol Ther. 2009;29:75-82.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 75-82
    • Andoh, A.1    Tsujikawa, T.2    Sasaki, M.3
  • 69
    • 44349164525 scopus 로고    scopus 로고
    • Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease
    • Takaishi H, Matsuki T, Nakazawa A, et al. Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease. Int J Med Microbiol. 2008;298:463-472.
    • (2008) Int J Med Microbiol , vol.298 , pp. 463-472
    • Takaishi, H.1    Matsuki, T.2    Nakazawa, A.3
  • 70
    • 34250375140 scopus 로고    scopus 로고
    • Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease
    • Sepehri S, Kotlowski R, Bernstein CN, et al. Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease. Inflamm Bowel Dis. 2007;13:675-683.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 675-683
    • Sepehri, S.1    Kotlowski, R.2    Bernstein, C.N.3
  • 71
    • 33750932588 scopus 로고    scopus 로고
    • Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease
    • Scanlan PD, Shanahan F, O'Mahony C, et al. Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease. J Clin Microbiol. 2006;44: 3980-3988.
    • (2006) J Clin Microbiol , vol.44 , pp. 3980-3988
    • Scanlan, P.D.1    Shanahan, F.2    O'Mahony, C.3
  • 72
    • 33645019411 scopus 로고    scopus 로고
    • Specificities of the fecal microbiota in inflammatory bowel disease
    • Sokol H, Seksik P, Rigottier-Gois L, et al. Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis. 2006; 12:106-111.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 106-111
    • Sokol, H.1    Seksik, P.2    Rigottier-Gois, L.3
  • 73
    • 33747050143 scopus 로고    scopus 로고
    • The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    • Bibiloni R, Mangold M, Madsen KL, et al. The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. J Med Microbiol. 2006;55:1141-1149.
    • (2006) J Med Microbiol , vol.55 , pp. 1141-1149
    • Bibiloni, R.1    Mangold, M.2    Madsen, K.L.3
  • 74
    • 33750956239 scopus 로고    scopus 로고
    • Differences between tissueassociated intestinal microfloras of patients with Crohn's disease and ulcerative colitis
    • Gophna U, Sommerfeld K, Gophna S, et al. Differences between tissueassociated intestinal microfloras of patients with Crohn's disease and ulcerative colitis. J Clin Microbiol. 2006;44:4136-4141.
    • (2006) J Clin Microbiol , vol.44 , pp. 4136-4141
    • Gophna, U.1    Sommerfeld, K.2    Gophna, S.3
  • 76
    • 2342442430 scopus 로고    scopus 로고
    • Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
    • Ott SJ, Musfeldt M, Wenderoth DF, et al. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut. 2004;53:685-693.
    • (2004) Gut , vol.53 , pp. 685-693
    • Ott, S.J.1    Musfeldt, M.2    Wenderoth, D.F.3
  • 77
    • 24744444522 scopus 로고    scopus 로고
    • Search for localized dysbiosis in Crohn's disease ulcerations by temporal temperature gradient gel electrophoresis of 16S rRNA
    • Seksik P, Lepage P, de la Cochetiere MF, et al. Search for localized dysbiosis in Crohn's disease ulcerations by temporal temperature gradient gel electrophoresis of 16S rRNA. J Clin Microbiol. 2005;43:4654-4658.
    • (2005) J Clin Microbiol , vol.43 , pp. 4654-4658
    • Seksik, P.1    Lepage, P.2    De La Cochetiere, M.F.3
  • 78
    • 84898738612 scopus 로고    scopus 로고
    • The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models
    • Martin R, Chain F, Miquel S, et al. The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis. 2014;20:417-430.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 417-430
    • Martin, R.1    Chain, F.2    Miquel, S.3
  • 79
    • 84902150181 scopus 로고    scopus 로고
    • Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease
    • Rajca S, Grondin V, Louis E, et al. Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease. Inflamm Bowel Dis. 2014;20:978-986.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 978-986
    • Rajca, S.1    Grondin, V.2    Louis, E.3
  • 80
    • 84875294514 scopus 로고    scopus 로고
    • Xenobiotics and the human gut microbiome: Metatranscriptomics reveal the active players
    • Ursell LK, Knight R. Xenobiotics and the human gut microbiome: metatranscriptomics reveal the active players. Cell Metab. 2013;17:317-318.
    • (2013) Cell Metab , vol.17 , pp. 317-318
    • Ursell, L.K.1    Knight, R.2
  • 81
    • 79953170241 scopus 로고    scopus 로고
    • Effect of antibiotic treatment on the intestinal metabolome
    • Antunes LC, Han J, Ferreira RB, et al. Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother. 2011;55: 1494-1503.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1494-1503
    • Antunes, L.C.1    Han, J.2    Ferreira, R.B.3
  • 82
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc Natl Acad Sci USA. 2011;108(suppl 1):4554-4561.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 83
    • 0036117798 scopus 로고    scopus 로고
    • Changes in the bacterial flora of the neoterminal ileum after ileocolonic resection for Crohn's disease
    • Neut C, Bulois P, Desreumaux P, et al. Changes in the bacterial flora of the neoterminal ileum after ileocolonic resection for Crohn's disease. Am J Gastroenterol. 2002;97:939-946.
    • (2002) Am J Gastroenterol , vol.97 , pp. 939-946
    • Neut, C.1    Bulois, P.2    Desreumaux, P.3
  • 84
    • 84882297193 scopus 로고    scopus 로고
    • Association of gut microbiota with post-operative clinical course in Crohn's disease
    • Dey N, Soergel DA, Repo S, et al. Association of gut microbiota with post-operative clinical course in Crohn's disease. BMC Gastroenterol. 2013;13:131.
    • (2013) BMC Gastroenterol , vol.13 , pp. 131
    • Dey, N.1    Soergel, D.A.2    Repo, S.3
  • 85
    • 84921481734 scopus 로고    scopus 로고
    • Specific mucosa-associated microbiota in Crohn's disease at the time of resection are associated with early disease recurrence: A Pilot Study
    • De Cruz P, Kang S, Wagner J, et al. Specific mucosa-associated microbiota in Crohn's disease at the time of resection are associated with early disease recurrence: a Pilot Study. J Gastroenterol Hepatol. 2015;30:268-278.
    • (2015) J Gastroenterol Hepatol , vol.30 , pp. 268-278
    • De Cruz, P.1    Kang, S.2    Wagner, J.3
  • 86
    • 4444236381 scopus 로고    scopus 로고
    • Short chain fatty acid regulation of signaling genes expressed by the intestinal epithelium
    • Sanderson IR. Short chain fatty acid regulation of signaling genes expressed by the intestinal epithelium. J Nutr. 2004;134:2450S-2454S.
    • (2004) J Nutr , vol.134 , pp. 2450S-2454S
    • Sanderson, I.R.1
  • 87
    • 84870322666 scopus 로고    scopus 로고
    • Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease
    • Erickson AR, Cantarel BL, Lamendella R, et al. Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease. PLoS One. 2012;7:e49138.
    • (2012) PLoS One , vol.7 , pp. e49138
    • Erickson, A.R.1    Cantarel, B.L.2    Lamendella, R.3
  • 88
    • 0033863238 scopus 로고    scopus 로고
    • Butyrate inhibits inflammatory responses through NF kappa B inhibition: Implications for Crohn's disease
    • Segain JP, Raingeard de la Bletiere D, Bourreille A, et al. Butyrate inhibits inflammatory responses through NF kappa B inhibition: implications for Crohn's disease. Gut. 2000;47:397-403.
    • (2000) Gut , vol.47 , pp. 397-403
    • Segain, J.P.1    Raingeard De La Bletiere, D.2    Bourreille, A.3
  • 89
    • 78349271212 scopus 로고    scopus 로고
    • Desulfovibrio bacterial species are increased in ulcerative colitis
    • Rowan F, Docherty NG, Murphy M, et al. Desulfovibrio bacterial species are increased in ulcerative colitis. Dis Colon Rectum. 2010;53: 1530-1536.
    • (2010) Dis Colon Rectum , vol.53 , pp. 1530-1536
    • Rowan, F.1    Docherty, N.G.2    Murphy, M.3
  • 90
    • 84879258302 scopus 로고    scopus 로고
    • Increase of faecal tryptic activity relates to changes in the intestinal microbiome: Analysis of Crohn's disease with a multidisciplinary platform
    • Midtvedt T, Zabarovsky E, Norin E, et al. Increase of faecal tryptic activity relates to changes in the intestinal microbiome: analysis of Crohn's disease with a multidisciplinary platform. PLoS One. 2013;8:e66074.
    • (2013) PLoS One , vol.8 , pp. e66074
    • Midtvedt, T.1    Zabarovsky, E.2    Norin, E.3


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