-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes
-
Huntington’s Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell. 1993;72(6):971–83.
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
-
2
-
-
2942625910
-
Differential loss of striatal projection systems in Huntington’s disease: a quantitative immunohistochemical study
-
COI: 1:STN:280:DC%2BD2c3otl2jsQ%3D%3D, PID: 15183201
-
Deng YP, et al. Differential loss of striatal projection systems in Huntington’s disease: a quantitative immunohistochemical study. J Chem Neuroanat. 2004;27(3):143–64.
-
(2004)
J Chem Neuroanat
, vol.27
, Issue.3
, pp. 143-164
-
-
Deng, Y.P.1
-
3
-
-
0001589776
-
Differential loss of striatal projection neurons in Huntington disease
-
COI: 1:STN:280:DyaL1c3ovFOqsw%3D%3D, PID: 2456581
-
Reiner A, et al. Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci. 1988;85(15):5733–7.
-
(1988)
Proc Natl Acad Sci
, vol.85
, Issue.15
, pp. 5733-5737
-
-
Reiner, A.1
-
4
-
-
58149189835
-
Tetrabenazine
-
COI: 1:CAS:528:DC%2BD1cXhsFCku7zO, PID: 19116624
-
Hayden MR, et al. Tetrabenazine. Nat Rev Drug Discov. 2009;8(1):17–8.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.1
, pp. 17-18
-
-
Hayden, M.R.1
-
5
-
-
84874201382
-
Analysis of CYP2D6 genotype and response to tetrabenazine
-
COI: 1:CAS:528:DC%2BC3sXktlCgsLg%3D, PID: 23280482
-
Mehanna R, et al. Analysis of CYP2D6 genotype and response to tetrabenazine. Mov Disord. 2013;28(2):210–5.
-
(2013)
Mov Disord
, vol.28
, Issue.2
, pp. 210-215
-
-
Mehanna, R.1
-
6
-
-
33847731495
-
Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders
-
PID: 17133512
-
Kenney C, Hunter C, Jankovic J. Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. Mov Disord. 2007;22(2):193–7.
-
(2007)
Mov Disord
, vol.22
, Issue.2
, pp. 193-197
-
-
Kenney, C.1
Hunter, C.2
Jankovic, J.3
-
7
-
-
33645798913
-
Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial
-
Huntington Study Group. Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. Neurology. 2006;66(3):366–72.
-
(2006)
Neurology
, vol.66
, Issue.3
, pp. 366-372
-
-
-
9
-
-
59849086625
-
The long-term effect of tetrabenazine in the management of Huntington disease
-
COI: 1:CAS:528:DC%2BD1cXhsVCrsL%2FO, PID: 19050408
-
Fasano A, et al. The long-term effect of tetrabenazine in the management of Huntington disease. Clin Neuropharmacol. 2008;31(6):313–8.
-
(2008)
Clin Neuropharmacol
, vol.31
, Issue.6
, pp. 313-318
-
-
Fasano, A.1
-
10
-
-
41249090997
-
A study of chorea after tetrabenazine withdrawal in patients with Huntington disease
-
COI: 1:CAS:528:DC%2BD1cXmsFymu7k%3D, PID: 18520979
-
Frank S, et al. A study of chorea after tetrabenazine withdrawal in patients with Huntington disease. Clin Neuropharmacol. 2008;31(3):127–33.
-
(2008)
Clin Neuropharmacol
, vol.31
, Issue.3
, pp. 127-133
-
-
Frank, S.1
-
11
-
-
84907929491
-
Safety and efficacy of tetrabenazine and use of concomitant medications during long-term, open-label treatment of chorea associated with Huntington’s and other diseases
-
Shen V, et al. Safety and efficacy of tetrabenazine and use of concomitant medications during long-term, open-label treatment of chorea associated with Huntington’s and other diseases. Tremor Other Hyperkinet Mov. 2013;3
-
(2013)
Tremor Other Hyperkinet Mov
, pp. 3
-
-
Shen, V.1
-
12
-
-
84906923097
-
Depressed mood and suicidality in individuals exposed to tetrabenazine in a large Huntington disease observational study
-
COI: 1:CAS:528:DC%2BC2cXosFSl, PID: 25062735
-
Dorsey ER, et al. Depressed mood and suicidality in individuals exposed to tetrabenazine in a large Huntington disease observational study. J Huntingtons Dis. 2013;2(4):509–15.
-
(2013)
J Huntingtons Dis
, vol.2
, Issue.4
, pp. 509-515
-
-
Dorsey, E.R.1
-
13
-
-
84977592334
-
Effect of deutetrabenazine on chorea among patients with Huntington disease: a randomized clinical trial
-
COI: 1:CAS:528:DC%2BC28XhtlOlu77M, PID: 27380342, A recent trial testing a novel molecule containing deuterium bound to tetrabenazine (TBZ), used to prolong the half-life of TBZ and decrease the side effects. This new medication could potentially allow for better control of chorea with fewer side effects
-
•• Frank S, et al. Effect of deutetrabenazine on chorea among patients with Huntington disease: a randomized clinical trial. JAMA. 2016;316(1):40–50. A recent trial testing a novel molecule containing deuterium bound to tetrabenazine (TBZ), used to prolong the half-life of TBZ and decrease the side effects. This new medication could potentially allow for better control of chorea with fewer side effects
-
(2016)
JAMA
, vol.316
, Issue.1
, pp. 40-50
-
-
Frank, S.1
-
14
-
-
0016276793
-
Letter: double-blind trial of lithium carbonate and haloperidol in Huntington’s chorea
-
COI: 1:STN:280:DyaE2M%2FksVGgsA%3D%3D, PID: 4139622
-
Leonard DP, et al. Letter: double-blind trial of lithium carbonate and haloperidol in Huntington’s chorea. Lancet. 1974;2(7890):1208–9.
-
(1974)
Lancet
, vol.2
, Issue.7890
, pp. 1208-1209
-
-
Leonard, D.P.1
-
15
-
-
0019444436
-
Huntington disease: functional capacities in patients treated with neuroleptic and antidepressant drugs
-
COI: 1:STN:280:DyaL383nt12nug%3D%3D, PID: 6125919
-
Shoulson I. Huntington disease: functional capacities in patients treated with neuroleptic and antidepressant drugs. Neurology. 1981;31(10):1333–5.
-
(1981)
Neurology
, vol.31
, Issue.10
, pp. 1333-1335
-
-
Shoulson, I.1
-
16
-
-
0018878029
-
Huntington’s disease: clinical effects of a short-term treatment with pimozide
-
COI: 1:STN:280:DyaL3c3mt1CmtA%3D%3D, PID: 6447434
-
Arena R, et al. Huntington’s disease: clinical effects of a short-term treatment with pimozide. Adv Biochem Psychopharmacol. 1980;24:573–5.
-
(1980)
Adv Biochem Psychopharmacol
, vol.24
, pp. 573-575
-
-
Arena, R.1
-
17
-
-
0017067441
-
Fluphenazine decanoate in the treatment of chorea: a double-blind study
-
COI: 1:STN:280:DyaE283ls1Gmug%3D%3D, PID: 133787
-
Terrence CF. Fluphenazine decanoate in the treatment of chorea: a double-blind study. Curr Ther Res Clin Exp. 1976;20(2):177–83.
-
(1976)
Curr Ther Res Clin Exp
, vol.20
, Issue.2
, pp. 177-183
-
-
Terrence, C.F.1
-
18
-
-
0030790234
-
Clozapine versus placebo in Huntington’s disease: a double blind randomised comparative study
-
PID: 9221965
-
van Vugt JP, et al. Clozapine versus placebo in Huntington’s disease: a double blind randomised comparative study. J Neurol Neurosurg Psychiatry. 1997;63(1):35–9.
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.63
, Issue.1
, pp. 35-39
-
-
van Vugt, J.P.1
-
19
-
-
0028341579
-
Clozapine in Huntington’s chorea
-
COI: 1:STN:280:DyaK2c3kslKmsg%3D%3D, PID: 8190281
-
Bonuccelli U, et al. Clozapine in Huntington’s chorea. Neurology. 1994;44(5):821–3.
-
(1994)
Neurology
, vol.44
, Issue.5
, pp. 821-823
-
-
Bonuccelli, U.1
-
20
-
-
0036709253
-
Olanzapine for Huntington’s disease: an open label study
-
COI: 1:CAS:528:DC%2BD38XovFShsr0%3D, PID: 12410058
-
Bonelli RM, Mahnert FA, Niederwieser G. Olanzapine for Huntington’s disease: an open label study. Clin Neuropharmacol. 2002;25(5):263–5.
-
(2002)
Clin Neuropharmacol
, vol.25
, Issue.5
, pp. 263-265
-
-
Bonelli, R.M.1
Mahnert, F.A.2
Niederwieser, G.3
-
21
-
-
0036276160
-
Olanzapine in Huntington’s disease
-
COI: 1:CAS:528:DC%2BD38Xlt1Cms7Y%3D, PID: 12027832
-
Paleacu D, Anca M, Giladi N. Olanzapine in Huntington’s disease. Acta Neurol Scand. 2002;105(6):441–4.
-
(2002)
Acta Neurol Scand
, vol.105
, Issue.6
, pp. 441-444
-
-
Paleacu, D.1
Anca, M.2
Giladi, N.3
-
22
-
-
0035118773
-
Short-term effects of olanzapine in Huntington disease
-
COI: 1:STN:280:DC%2BD3M3lvVKhsQ%3D%3D, PID: 11234911
-
Squitieri F, et al. Short-term effects of olanzapine in Huntington disease. Neuropsychiatry Neuropsychol Behav Neurol. 2001;14(1):69–72.
-
(2001)
Neuropsychiatry Neuropsychol Behav Neurol
, vol.14
, Issue.1
, pp. 69-72
-
-
Squitieri, F.1
-
23
-
-
61449249292
-
Treatment of the symptoms of Huntington’s disease: preliminary results comparing aripiprazole and tetrabenazine
-
PID: 19170197
-
Brusa L, et al. Treatment of the symptoms of Huntington’s disease: preliminary results comparing aripiprazole and tetrabenazine. Mov Disord. 2009;24(1):126–9.
-
(2009)
Mov Disord
, vol.24
, Issue.1
, pp. 126-129
-
-
Brusa, L.1
-
24
-
-
33746687898
-
Clinical experience with risperidone and memantine in the treatment of Huntington’s disease
-
PID: 16916137
-
Cankurtaran ES, et al. Clinical experience with risperidone and memantine in the treatment of Huntington’s disease. J Natl Med Assoc. 2006;98(8):1353–5.
-
(2006)
J Natl Med Assoc
, vol.98
, Issue.8
, pp. 1353-1355
-
-
Cankurtaran, E.S.1
-
25
-
-
0036038875
-
Risperidone in chorea and psychosis of Huntington’s disease
-
PID: 11882064
-
Erdemoglu AK, Boratav C. Risperidone in chorea and psychosis of Huntington’s disease. Eur J Neurol. 2002;9(2):182–3.
-
(2002)
Eur J Neurol
, vol.9
, Issue.2
, pp. 182-183
-
-
Erdemoglu, A.K.1
Boratav, C.2
-
26
-
-
0030938246
-
Risperidone in treatment of choreoathetosis of Huntington’s disease
-
COI: 1:STN:280:DC%2BD3cvitFWmtw%3D%3D, PID: 10950488
-
Parsa MA, et al. Risperidone in treatment of choreoathetosis of Huntington’s disease. J Clin Psychopharmacol. 1997;17(2):134–5.
-
(1997)
J Clin Psychopharmacol
, vol.17
, Issue.2
, pp. 134-135
-
-
Parsa, M.A.1
-
27
-
-
0036041559
-
Quetiapine in Huntington’s disease: a first case report
-
PID: 12420714
-
Bonelli RM, Niederwieser G. Quetiapine in Huntington’s disease: a first case report. J Neurol. 2002;249(8):1114–5.
-
(2002)
J Neurol
, vol.249
, Issue.8
, pp. 1114-1115
-
-
Bonelli, R.M.1
Niederwieser, G.2
-
28
-
-
0347285447
-
Ziprasidone in Huntington’s disease: the first case reports
-
PID: 14870962
-
Bonelli RM, et al. Ziprasidone in Huntington’s disease: the first case reports. J Psychopharmacol. 2003;17(4):459–60.
-
(2003)
J Psychopharmacol
, vol.17
, Issue.4
, pp. 459-460
-
-
Bonelli, R.M.1
-
29
-
-
77957986360
-
Efficacy and safety of the dopaminergic stabilizer pridopidine (ACR16) in patients with Huntington’s disease
-
COI: 1:CAS:528:DC%2BC3cXht1WisrbF, PID: 20616707
-
Lundin A, et al. Efficacy and safety of the dopaminergic stabilizer pridopidine (ACR16) in patients with Huntington’s disease. Clin Neuropharmacol. 2010;33(5):260–4.
-
(2010)
Clin Neuropharmacol
, vol.33
, Issue.5
, pp. 260-264
-
-
Lundin, A.1
-
30
-
-
81255195330
-
Pridopidine for the treatment of motor function in patients with Huntington’s disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial
-
PID: 22071279
-
de Yebenes JG, et al. Pridopidine for the treatment of motor function in patients with Huntington’s disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2011;10(12):1049–57.
-
(2011)
Lancet Neurol
, vol.10
, Issue.12
, pp. 1049-1057
-
-
de Yebenes, J.G.1
-
31
-
-
84884724757
-
A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington’s disease
-
Huntington Study Group. A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington’s disease. Mov Disord. 2013;28(10):1407–15.
-
(2013)
Mov Disord
, vol.28
, Issue.10
, pp. 1407-1415
-
-
-
32
-
-
0037700247
-
IV amantadine improves chorea in Huntington,s disease: an acute randomized, controlled study
-
COI: 1:CAS:528:DC%2BD3sXksVGisrc%3D, PID: 12821751
-
Lucetti C, et al. IV amantadine improves chorea in Huntington,s disease: an acute randomized, controlled study. Neurology. 2003;60(12):1995–7.
-
(2003)
Neurology
, vol.60
, Issue.12
, pp. 1995-1997
-
-
Lucetti, C.1
-
33
-
-
0036757043
-
Amantadine in Huntington’s disease: open-label video-blinded study
-
PID: 12548355
-
Lucetti C, et al. Amantadine in Huntington’s disease: open-label video-blinded study. Neurol Sci. 2002;23(Suppl 2):S83–4.
-
(2002)
Neurol Sci
, vol.23
, pp. S83-S84
-
-
Lucetti, C.1
-
34
-
-
0037056392
-
Huntington’s disease: a randomized, controlled trial using the NMDA-antagonist amantadine
-
Verhagen ML, et al. Huntington’s disease: a randomized, controlled trial using the NMDA-antagonist amantadine. Neurology. 2002;59(5):694–9.
-
(2002)
Neurology
, vol.59
, Issue.5
, pp. 694-699
-
-
Verhagen, M.L.1
-
35
-
-
0038375825
-
A randomized trial of amantadine in Huntington disease
-
PID: 12873857
-
O’Suilleabhain P, Dewey RB. A randomized trial of amantadine in Huntington disease. Arch Neurol. 2003;60(7):996–8.
-
(2003)
Arch Neurol
, vol.60
, Issue.7
, pp. 996-998
-
-
O’Suilleabhain, P.1
Dewey, R.B.2
-
36
-
-
34948838383
-
Riluzole in Huntington’s disease: a 3-year, randomized controlled study
-
COI: 1:CAS:528:DC%2BD2sXht1CntrvO, PID: 17702031
-
Landwehrmeyer GB, et al. Riluzole in Huntington’s disease: a 3-year, randomized controlled study. Ann Neurol. 2007;62(3):262–72.
-
(2007)
Ann Neurol
, vol.62
, Issue.3
, pp. 262-272
-
-
Landwehrmeyer, G.B.1
-
37
-
-
0345600893
-
Dosage effects of riluzole in Huntington’s disease: a multicenter placebo-controlled study
-
Huntington Study Group. Dosage effects of riluzole in Huntington’s disease: a multicenter placebo-controlled study. Neurology. 2003;61(11):1551–6.
-
(2003)
Neurology
, vol.61
, Issue.11
, pp. 1551-1556
-
-
-
38
-
-
84866131013
-
Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology
-
PID: 22815556
-
Armstrong MJ, Miyasaki JM. Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology. Neurology. 2012;79(6):597–603.
-
(2012)
Neurology
, vol.79
, Issue.6
, pp. 597-603
-
-
Armstrong, M.J.1
Miyasaki, J.M.2
-
39
-
-
84957844104
-
Deep brain stimulation of the internal pallidum in Huntington’s disease patients: clinical outcome and neuronal firing patterns
-
PID: 26568561
-
Delorme C, et al. Deep brain stimulation of the internal pallidum in Huntington’s disease patients: clinical outcome and neuronal firing patterns. J Neurol. 2016;263(2):290–8.
-
(2016)
J Neurol
, vol.263
, Issue.2
, pp. 290-298
-
-
Delorme, C.1
-
40
-
-
84903892559
-
Deep brain stimulation for Huntington’s disease: long-term results of a prospective open-label study
-
PID: 24702329, Longitudinal case series of bilateral GPi DBS in patients with pharmacologically resistant chorea secondary to HD. Provides information about long-term outcomes of DBS therapy for chorea in HD
-
• Gonzalez V, et al. Deep brain stimulation for Huntington’s disease: long-term results of a prospective open-label study. J Neurosurg. 2014;121(1):114–22. Longitudinal case series of bilateral GPi DBS in patients with pharmacologically resistant chorea secondary to HD. Provides information about long-term outcomes of DBS therapy for chorea in HD
-
(2014)
J Neurosurg
, vol.121
, Issue.1
, pp. 114-122
-
-
Gonzalez, V.1
-
41
-
-
79951814028
-
Long-term follow-up of pallidal deep brain stimulation in two cases of Huntington’s disease
-
PID: 20974647
-
Kang GA, et al. Long-term follow-up of pallidal deep brain stimulation in two cases of Huntington’s disease. J Neurol Neurosurg Psychiatry. 2011;82(3):272–7.
-
(2011)
J Neurol Neurosurg Psychiatry
, vol.82
, Issue.3
, pp. 272-277
-
-
Kang, G.A.1
-
42
-
-
3843077481
-
Bilateral globus pallidus stimulation for Huntington’s disease
-
PID: 15293283
-
Moro E, et al. Bilateral globus pallidus stimulation for Huntington’s disease. Ann Neurol. 2004;56(2):290–4.
-
(2004)
Ann Neurol
, vol.56
, Issue.2
, pp. 290-294
-
-
Moro, E.1
-
43
-
-
84872786004
-
Differential and better response to deep brain stimulation of chorea compared to dystonia in Huntington’s disease
-
PID: 23343665
-
Velez-Lago FM, et al. Differential and better response to deep brain stimulation of chorea compared to dystonia in Huntington’s disease. Stereotact Funct Neurosurg. 2013;91(2):129–33.
-
(2013)
Stereotact Funct Neurosurg
, vol.91
, Issue.2
, pp. 129-133
-
-
Velez-Lago, F.M.1
-
44
-
-
84893636639
-
A 5-year follow-up of deep brain stimulation in Huntington’s disease
-
PID: 24300048
-
Lopez-Sendon Moreno JL, et al. A 5-year follow-up of deep brain stimulation in Huntington’s disease. Parkinsonism Relat Disord. 2014;20(2):260–1.
-
(2014)
Parkinsonism Relat Disord
, vol.20
, Issue.2
, pp. 260-261
-
-
Lopez-Sendon Moreno, J.L.1
-
45
-
-
84861706912
-
Deep brain stimulation in Huntington’s disease: a 4-year follow-up case report
-
PID: 22451258, author reply 807-8
-
Spielberger S, et al. Deep brain stimulation in Huntington’s disease: a 4-year follow-up case report. Mov Disord. 2012;27(6):806–7. author reply 807-8
-
(2012)
Mov Disord
, vol.27
, Issue.6
, pp. 806-807
-
-
Spielberger, S.1
-
46
-
-
0031785792
-
Levodopa responsive parkinsonism in an adult with Huntington’s disease
-
COI: 1:STN:280:DyaK1cvkt1Ogtg%3D%3D, PID: 9771791
-
Racette BA, Perlmutter JS. Levodopa responsive parkinsonism in an adult with Huntington’s disease. J Neurol Neurosurg Psychiatry. 1998;65(4):577–9.
-
(1998)
J Neurol Neurosurg Psychiatry
, vol.65
, Issue.4
, pp. 577-579
-
-
Racette, B.A.1
Perlmutter, J.S.2
-
47
-
-
0034057350
-
Late onset levodopa responsive Huntington’s disease with minimal chorea masquerading as Parkinson plus syndrome
-
COI: 1:STN:280:DC%2BD3c7ht12msA%3D%3D, PID: 10644798
-
Reuter I, et al. Late onset levodopa responsive Huntington’s disease with minimal chorea masquerading as Parkinson plus syndrome. J Neurol Neurosurg Psychiatry. 2000;68(2):238–41.
-
(2000)
J Neurol Neurosurg Psychiatry
, vol.68
, Issue.2
, pp. 238-241
-
-
Reuter, I.1
-
48
-
-
0019254352
-
Seven cases of Huntington’s disease in childhood and levodopa induced improvement in the hypokinetic—rigid form
-
COI: 1:STN:280:DyaL3M3htVOrug%3D%3D, PID: 6165509
-
Jongen PJ, Renier WO, Gabreels FJ. Seven cases of Huntington’s disease in childhood and levodopa induced improvement in the hypokinetic—rigid form. Clin Neurol Neurosurg. 1980;82(4):251–61.
-
(1980)
Clin Neurol Neurosurg
, vol.82
, Issue.4
, pp. 251-261
-
-
Jongen, P.J.1
Renier, W.O.2
Gabreels, F.J.3
-
49
-
-
46449134291
-
Long-term follow-up of Huntington disease treated by bilateral deep brain stimulation of the internal globus pallidus
-
PID: 18590443
-
Biolsi B, et al. Long-term follow-up of Huntington disease treated by bilateral deep brain stimulation of the internal globus pallidus. J Neurosurg. 2008;109(1):130–2.
-
(2008)
J Neurosurg
, vol.109
, Issue.1
, pp. 130-132
-
-
Biolsi, B.1
-
50
-
-
33645461836
-
Cabergoline in Huntington’s disease: the first case report
-
COI: 1:STN:280:DC%2BD283it1Wgtw%3D%3D, PID: 16629775
-
Magnet MK, Kapfhammer HP, Bonelli RM. Cabergoline in Huntington’s disease: the first case report. Acta Neurol Scand. 2006;113(5):355–6.
-
(2006)
Acta Neurol Scand
, vol.113
, Issue.5
, pp. 355-356
-
-
Magnet, M.K.1
Kapfhammer, H.P.2
Bonelli, R.M.3
-
51
-
-
0036182828
-
Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington’s disease
-
PID: 11852299
-
Bonelli RM, et al. Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington’s disease. Clin Neuropharmacol. 2002;25(1):58–60.
-
(2002)
Clin Neuropharmacol
, vol.25
, Issue.1
, pp. 58-60
-
-
Bonelli, R.M.1
-
52
-
-
84905174777
-
Bilateral globus pallidus stimulation in Westphal variant of Huntington disease
-
PID: 24024832
-
Cislaghi G, et al. Bilateral globus pallidus stimulation in Westphal variant of Huntington disease. Neuromodulation. 2014;17(5):502–5.
-
(2014)
Neuromodulation
, vol.17
, Issue.5
, pp. 502-505
-
-
Cislaghi, G.1
-
53
-
-
0033693353
-
Internal globus pallidotomy in dystonia secondary to Huntington’s disease
-
COI: 1:STN:280:DC%2BD3MzgsVagtg%3D%3D, PID: 11104214
-
Cubo E, et al. Internal globus pallidotomy in dystonia secondary to Huntington’s disease. Mov Disord. 2000;15(6):1248–51.
-
(2000)
Mov Disord
, vol.15
, Issue.6
, pp. 1248-1251
-
-
Cubo, E.1
-
54
-
-
33645216173
-
Dose-dependent improvement of myoclonic hyperkinesia due to valproic acid in eight Huntington’s disease patients: a case series
-
PID: 16507108
-
Saft C, et al. Dose-dependent improvement of myoclonic hyperkinesia due to valproic acid in eight Huntington’s disease patients: a case series. BMC Neurol. 2006;6:11.
-
(2006)
BMC Neurol
, vol.6
, pp. 11
-
-
Saft, C.1
-
55
-
-
0028077467
-
Cortical myoclonus in Huntington’s disease
-
COI: 1:STN:280:DyaK2M7ksl2jsg%3D%3D, PID: 7845404
-
Thompson PD, et al. Cortical myoclonus in Huntington’s disease. Mov Disord. 1994;9(6):633–41.
-
(1994)
Mov Disord
, vol.9
, Issue.6
, pp. 633-641
-
-
Thompson, P.D.1
-
56
-
-
0025965356
-
Myoclonus in adult Huntington’s disease
-
COI: 1:STN:280:DyaK3M7ovFKltg%3D%3D, PID: 1826419
-
Vogel CM, et al. Myoclonus in adult Huntington’s disease. Ann Neurol. 1991;29(2):213–5.
-
(1991)
Ann Neurol
, vol.29
, Issue.2
, pp. 213-215
-
-
Vogel, C.M.1
-
57
-
-
84885649254
-
Cognitive decline in prodromal Huntington disease: implications for clinical trials
-
PID: 23911948
-
Paulsen JS, Smith MM, Long JD. Cognitive decline in prodromal Huntington disease: implications for clinical trials. J Neurol Neurosurg Psychiatry. 2013;84(11):1233–9.
-
(2013)
J Neurol Neurosurg Psychiatry
, vol.84
, Issue.11
, pp. 1233-1239
-
-
Paulsen, J.S.1
Smith, M.M.2
Long, J.D.3
-
58
-
-
0029043634
-
Distinct cognitive profiles of cortical and subcortical dementia in advanced illness
-
COI: 1:STN:280:DyaK2M3msFajsA%3D%3D, PID: 7746413
-
Paulsen JS, et al. Distinct cognitive profiles of cortical and subcortical dementia in advanced illness. Neurology. 1995;45(5):951–6.
-
(1995)
Neurology
, vol.45
, Issue.5
, pp. 951-956
-
-
Paulsen, J.S.1
-
59
-
-
34248560852
-
Patients with Huntington’s disease have impaired awareness of cognitive, emotional, and functional abilities
-
Hoth KF, et al. Patients with Huntington’s disease have impaired awareness of cognitive, emotional, and functional abilities. J Clin Exp Neuropsychol. 2007;9(4):365–76.
-
(2007)
J Clin Exp Neuropsychol
, vol.9
, Issue.4
, pp. 365-376
-
-
Hoth, K.F.1
-
60
-
-
33846815309
-
Two years’ follow-up of rivastigmine treatment in Huntington disease
-
PID: 17272969
-
de Tommaso M, et al. Two years’ follow-up of rivastigmine treatment in Huntington disease. Clin Neuropharmacol. 2007;30(1):43–6.
-
(2007)
Clin Neuropharmacol
, vol.30
, Issue.1
, pp. 43-46
-
-
de Tommaso, M.1
-
61
-
-
0036834904
-
Rivastigmine in the treatment of Huntington’s disease
-
COI: 1:STN:280:DC%2BD38npt1GisA%3D%3D, PID: 12453090
-
Rot U, et al. Rivastigmine in the treatment of Huntington’s disease. Eur J Neurol. 2002;9(6):689–90.
-
(2002)
Eur J Neurol
, vol.9
, Issue.6
, pp. 689-690
-
-
Rot, U.1
-
62
-
-
84907167457
-
Cognitive function in early clinical phase Huntington disease after rivastigmine treatment
-
COI: 1:CAS:528:DC%2BC2cXhvFejtLfM, PID: 25191771
-
Sesok S, et al. Cognitive function in early clinical phase Huntington disease after rivastigmine treatment. Psychiatr Danub. 2014;26(3):239–48.
-
(2014)
Psychiatr Danub
, vol.26
, Issue.3
, pp. 239-248
-
-
Sesok, S.1
-
63
-
-
33749861388
-
Effect of donepezil on motor and cognitive function in Huntington disease
-
COI: 1:CAS:528:DC%2BD28XhtFyqtb7M, PID: 17030764
-
Cubo E, et al. Effect of donepezil on motor and cognitive function in Huntington disease. Neurology. 2006;67(7):1268–71.
-
(2006)
Neurology
, vol.67
, Issue.7
, pp. 1268-1271
-
-
Cubo, E.1
-
64
-
-
34548814154
-
A pilot study of the clinical efficacy and safety of memantine for Huntington’s disease
-
PID: 17046312
-
Ondo WG, Mejia NI, Hunter CB. A pilot study of the clinical efficacy and safety of memantine for Huntington’s disease. Parkinsonism Relat Disord. 2007;13(7):453–4.
-
(2007)
Parkinsonism Relat Disord
, vol.13
, Issue.7
, pp. 453-454
-
-
Ondo, W.G.1
Mejia, N.I.2
Hunter, C.B.3
-
65
-
-
4544335687
-
The N-methyl-D-aspartate antagonist memantine retards progression of Huntington’s disease
-
COI: 1:CAS:528:DC%2BD2MXht1CgurfK
-
Beister A, et al. The N-methyl-D-aspartate antagonist memantine retards progression of Huntington’s disease. J Neural Transm Suppl. 2004;68:117–22.
-
(2004)
J Neural Transm Suppl
, vol.68
, pp. 117-122
-
-
Beister, A.1
-
66
-
-
0034881096
-
Neuropsychiatric aspects of Huntington’s disease
-
COI: 1:STN:280:DC%2BD3Mvms12hsQ%3D%3D, PID: 11511702
-
Paulsen JS, et al. Neuropsychiatric aspects of Huntington’s disease. J Neurol Neurosurg Psychiatry. 2001;71(3):310–4.
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.71
, Issue.3
, pp. 310-314
-
-
Paulsen, J.S.1
-
67
-
-
0031849018
-
Apathy is not depression
-
COI: 1:STN:280:DyaK1czntFyhug%3D%3D, PID: 9706539
-
Levy ML, et al. Apathy is not depression. J Neuropsychiatry Clin Neurosci. 1998;10(3):314–9.
-
(1998)
J Neuropsychiatry Clin Neurosci
, vol.10
, Issue.3
, pp. 314-319
-
-
Levy, M.L.1
-
68
-
-
36549036813
-
Psychiatric symptoms in Huntington’s disease before diagnosis: the predict-HD study
-
PID: 17481592
-
Duff K, et al. Psychiatric symptoms in Huntington’s disease before diagnosis: the predict-HD study. Biol Psychiatry. 2007;62(12):1341–6.
-
(2007)
Biol Psychiatry
, vol.62
, Issue.12
, pp. 1341-1346
-
-
Duff, K.1
-
69
-
-
0346502764
-
Cognitive and psychiatric aspects of Huntington disease contribute to functional capacity
-
PID: 14718780
-
Nehl C, Paulsen JS. Cognitive and psychiatric aspects of Huntington disease contribute to functional capacity. J Nerv Ment Dis. 2004;192(1):72–4.
-
(2004)
J Nerv Ment Dis
, vol.192
, Issue.1
, pp. 72-74
-
-
Nehl, C.1
Paulsen, J.S.2
-
70
-
-
84900376687
-
Neuropsychiatric symptoms in a European Huntington’s disease cohort (REGISTRY)
-
PID: 24828898
-
van Duijn E, et al. Neuropsychiatric symptoms in a European Huntington’s disease cohort (REGISTRY). J Neurol Neurosurg Psychiatry. 2014;85(12):1411–8.
-
(2014)
J Neurol Neurosurg Psychiatry
, vol.85
, Issue.12
, pp. 1411-1418
-
-
van Duijn, E.1
-
72
-
-
84927518627
-
Systematic review of pharmacological treatments for depressive symptoms in Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2cXhslajsrbN, PID: 25111961
-
Moulton CD, Hopkins CW, Bevan-Jones WR. Systematic review of pharmacological treatments for depressive symptoms in Huntington’s disease. Mov Disord. 2014;29(12):1556–61.
-
(2014)
Mov Disord
, vol.29
, Issue.12
, pp. 1556-1561
-
-
Moulton, C.D.1
Hopkins, C.W.2
Bevan-Jones, W.R.3
-
73
-
-
16744362352
-
A controlled trial of fluoxetine in nondepressed patients with Huntington’s disease
-
COI: 1:STN:280:DyaK2szgtlCisg%3D%3D, PID: 9159735
-
Como PG, et al. A controlled trial of fluoxetine in nondepressed patients with Huntington’s disease. Mov Disord. 1997;12(3):397–401.
-
(1997)
Mov Disord
, vol.12
, Issue.3
, pp. 397-401
-
-
Como, P.G.1
-
74
-
-
84896110683
-
Results of the citalopram to enhance cognition in Huntington disease trial
-
COI: 1:CAS:528:DC%2BC2cXktlChu7s%3D, PID: 24375941
-
Beglinger LJ, et al. Results of the citalopram to enhance cognition in Huntington disease trial. Mov Disord. 2014;29(3):401–5.
-
(2014)
Mov Disord
, vol.29
, Issue.3
, pp. 401-405
-
-
Beglinger, L.J.1
-
75
-
-
73449100113
-
Combating depression in Huntington’s disease: effective antidepressive treatment with venlafaxine XR
-
PID: 19996754
-
Holl AK, et al. Combating depression in Huntington’s disease: effective antidepressive treatment with venlafaxine XR. Int Clin Psychopharmacol. 2010;25(1):46–50.
-
(2010)
Int Clin Psychopharmacol
, vol.25
, Issue.1
, pp. 46-50
-
-
Holl, A.K.1
-
76
-
-
39749165003
-
Risperidone and the treatment of psychiatric, motor, and cognitive symptoms in Huntington’s disease
-
PID: 18297579
-
Duff K, et al. Risperidone and the treatment of psychiatric, motor, and cognitive symptoms in Huntington’s disease. Ann Clin Psychiatry. 2008;20(1):1–3.
-
(2008)
Ann Clin Psychiatry
, vol.20
, Issue.1
, pp. 1-3
-
-
Duff, K.1
-
77
-
-
70449710919
-
Aripiprazole in the treatment of Huntington’s disease: a case series
-
COI: 1:CAS:528:DC%2BD1MXitFWls7k%3D, PID: 19557093
-
Ciammola A, et al. Aripiprazole in the treatment of Huntington’s disease: a case series. Neuropsychiatr Dis Treat. 2009;5:1–4.
-
(2009)
Neuropsychiatr Dis Treat
, vol.5
, pp. 1-4
-
-
Ciammola, A.1
-
78
-
-
0025977935
-
Clozapine treatment of psychiatric symptoms resistant to neuroleptic treatment in patients with Huntington’s chorea
-
COI: 1:STN:280:DyaK3M%2FovVSktg%3D%3D, PID: 1670739
-
Sajatovic M, et al. Clozapine treatment of psychiatric symptoms resistant to neuroleptic treatment in patients with Huntington’s chorea. Neurology. 1991;41(1):156.
-
(1991)
Neurology
, vol.41
, Issue.1
, pp. 156
-
-
Sajatovic, M.1
-
79
-
-
79951513261
-
Risperidone long-acting injection and Huntington’s disease: case series with significant psychiatric and behavioural symptoms
-
PID: 21119522
-
Johnston TG. Risperidone long-acting injection and Huntington’s disease: case series with significant psychiatric and behavioural symptoms. Int Clin Psychopharmacol. 2011;26(2):114–9.
-
(2011)
Int Clin Psychopharmacol
, vol.26
, Issue.2
, pp. 114-119
-
-
Johnston, T.G.1
-
80
-
-
0029875455
-
ECT in genetically confirmed Huntington’s disease
-
COI: 1:STN:280:DyaK2s7htVyktg%3D%3D, PID: 9081559
-
Lewis CF, DeQuardo JR, Tandon R. ECT in genetically confirmed Huntington’s disease. J Neuropsychiatry Clin Neurosci. 1996;8(2):209–10.
-
(1996)
J Neuropsychiatry Clin Neurosci
, vol.8
, Issue.2
, pp. 209-210
-
-
Lewis, C.F.1
DeQuardo, J.R.2
Tandon, R.3
-
81
-
-
0028349632
-
ECT as a treatment for depression in Huntington’s disease
-
COI: 1:STN:280:DyaK2czhvFWktA%3D%3D, PID: 8044037
-
Ranen NG, Peyser CE, Folstein SE. ECT as a treatment for depression in Huntington’s disease. J Neuropsychiatry Clin Neurosci. 1994;6(2):154–9.
-
(1994)
J Neuropsychiatry Clin Neurosci
, vol.6
, Issue.2
, pp. 154-159
-
-
Ranen, N.G.1
Peyser, C.E.2
Folstein, S.E.3
-
82
-
-
84887032790
-
Rapid improvement of depression and psychotic symptoms in Huntington’s disease: a retrospective chart review of seven patients treated with electroconvulsive therapy
-
PID: 23541803, e3-5
-
Cusin C, et al. Rapid improvement of depression and psychotic symptoms in Huntington’s disease: a retrospective chart review of seven patients treated with electroconvulsive therapy. Gen Hosp Psychiatry. 2013;35(6):678. e3-5
-
(2013)
Gen Hosp Psychiatry
, vol.35
, Issue.6
, pp. 678
-
-
Cusin, C.1
-
83
-
-
29044431699
-
Depression and stages of Huntington’s disease
-
PID: 16387989
-
Paulsen JS, et al. Depression and stages of Huntington’s disease. J Neuropsychiatry Clin Neurosci. 2005;17(4):496–502.
-
(2005)
J Neuropsychiatry Clin Neurosci
, vol.17
, Issue.4
, pp. 496-502
-
-
Paulsen, J.S.1
-
84
-
-
0027467546
-
Suicide risk in Huntington’s disease
-
COI: 1:STN:280:DyaK3s3ltlOntg%3D%3D, PID: 8487273
-
Di Maio L, et al. Suicide risk in Huntington’s disease. J Med Genet. 1993;30(4):293–5.
-
(1993)
J Med Genet
, vol.30
, Issue.4
, pp. 293-295
-
-
Di Maio, L.1
-
85
-
-
0027134654
-
Risk factors for suicide in Huntingtons disease: a retrospective case controlled study
-
COI: 1:STN:280:DyaK2c7ot1Kktw%3D%3D, PID: 8135306
-
Lipe H, Schultz A, Bird TD. Risk factors for suicide in Huntingtons disease: a retrospective case controlled study. Am J Med Genet. 1993;48(4):231–3.
-
(1993)
Am J Med Genet
, vol.48
, Issue.4
, pp. 231-233
-
-
Lipe, H.1
Schultz, A.2
Bird, T.D.3
-
86
-
-
79960696876
-
Suicidal ideation in Huntington disease: the role of comorbidity
-
PID: 21605914
-
Wetzel HH, et al. Suicidal ideation in Huntington disease: the role of comorbidity. Psychiatry Res. 2011;188(3):372–6.
-
(2011)
Psychiatry Res
, vol.188
, Issue.3
, pp. 372-376
-
-
Wetzel, H.H.1
-
87
-
-
80755128156
-
Treatment of apathy in Huntington’s disease and other movement disorders
-
PID: 21800056
-
Krishnamoorthy A, Craufurd D. Treatment of apathy in Huntington’s disease and other movement disorders. Curr Treat Options Neurol. 2011;13(5):508–19.
-
(2011)
Curr Treat Options Neurol
, vol.13
, Issue.5
, pp. 508-519
-
-
Krishnamoorthy, A.1
Craufurd, D.2
-
88
-
-
0035140902
-
Fluoxetine in the treatment of Huntington’s disease
-
COI: 1:CAS:528:DC%2BD3MXhtlGiurg%3D, PID: 11205429
-
De Marchi N, Daniele F, Ragone MA. Fluoxetine in the treatment of Huntington’s disease. Psychopharmacology. 2001;153(2):264–6.
-
(2001)
Psychopharmacology
, vol.153
, Issue.2
, pp. 264-266
-
-
De Marchi, N.1
Daniele, F.2
Ragone, M.A.3
-
89
-
-
0036713657
-
Obsessive compulsive disorder in Huntington disease: a case of isolated obsessions successfully treated with sertraline
-
PID: 12218715
-
Patzold T, Brune M. Obsessive compulsive disorder in Huntington disease: a case of isolated obsessions successfully treated with sertraline. Neuropsychiatry Neuropsychol Behav Neurol. 2002;15(3):216–9.
-
(2002)
Neuropsychiatry Neuropsychol Behav Neurol
, vol.15
, Issue.3
, pp. 216-219
-
-
Patzold, T.1
Brune, M.2
-
90
-
-
84863702589
-
An international survey-based algorithm for the pharmacologic treatment of obsessive-compulsive behaviors in Huntington’s disease
-
PID: 21947193
-
Anderson K, et al. An international survey-based algorithm for the pharmacologic treatment of obsessive-compulsive behaviors in Huntington’s disease. PLoS Curr. 2011;3:Rrn1261.
-
(2011)
PLoS Curr
, vol.3
, pp. Rrn1261
-
-
Anderson, K.1
-
91
-
-
0029793158
-
Sertraline in the treatment of severe aggressiveness in Huntington’s disease
-
COI: 1:STN:280:DyaK2s%2FgslSgsA%3D%3D, PID: 8854307
-
Ranen NG, et al. Sertraline in the treatment of severe aggressiveness in Huntington’s disease. J Neuropsychiatry Clin Neurosci. 1996;8(3):338–40.
-
(1996)
J Neuropsychiatry Clin Neurosci
, vol.8
, Issue.3
, pp. 338-340
-
-
Ranen, N.G.1
-
92
-
-
84865652676
-
An international survey-based algorithm for the pharmacologic treatment of irritability in Huntington’s disease
-
PID: 21975525
-
Groves M, et al. An international survey-based algorithm for the pharmacologic treatment of irritability in Huntington’s disease. PLoS Curr. 2011;3:Rrn1259.
-
(2011)
PLoS Curr
, vol.3
, pp. Rrn1259
-
-
Groves, M.1
-
93
-
-
0031708158
-
Use of risperidone in psychosis associated with Huntington’s disease
-
COI: 1:STN:280:DyaK1M%2FgvF2rsg%3D%3D, PID: 9793585
-
Madhusoodanan S, Brenner R. Use of risperidone in psychosis associated with Huntington’s disease. Am J Geriatr Psychiatry. 1998;6(4):347–9.
-
(1998)
Am J Geriatr Psychiatry
, vol.6
, Issue.4
, pp. 347-349
-
-
Madhusoodanan, S.1
Brenner, R.2
-
94
-
-
3042733763
-
Quetiapine in the management of psychosis secondary to Huntington’s disease: a case report
-
Seitz DP, Millson RC. Quetiapine in the management of psychosis secondary to Huntington’s disease: a case report. Can J Psychiatr. 2004;49(6):413.
-
(2004)
Can J Psychiatr
, vol.49
, Issue.6
, pp. 413
-
-
Seitz, D.P.1
Millson, R.C.2
-
95
-
-
29544445190
-
Quetiapine in the treatment of behavioral disturbances in patients with Huntington’s disease
-
PID: 16384811
-
Alpay M, Koroshetz WJ. Quetiapine in the treatment of behavioral disturbances in patients with Huntington’s disease. Psychosomatics. 2006;47(1):70–2.
-
(2006)
Psychosomatics
, vol.47
, Issue.1
, pp. 70-72
-
-
Alpay, M.1
Koroshetz, W.J.2
-
96
-
-
84961752080
-
The genetic modifiers of motor onsetAge (GeM MOA) website: genome-wide association analysis for genetic modifiers of Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2MXhs1WqsrrF, PID: 26444025
-
Correia K, et al. The genetic modifiers of motor onsetAge (GeM MOA) website: genome-wide association analysis for genetic modifiers of Huntington’s disease. J Huntingtons Dis. 2015;4(3):279–84.
-
(2015)
J Huntingtons Dis
, vol.4
, Issue.3
, pp. 279-284
-
-
Correia, K.1
-
97
-
-
84938389137
-
Identification of genetic factors that modify clinical onset of Huntington’s disease
-
Genetic Modifiers of Huntington’s Disease Consortium. Identification of genetic factors that modify clinical onset of Huntington’s disease. Cell. 2015;162(3):516–26.
-
(2015)
Cell
, vol.162
, Issue.3
, pp. 516-526
-
-
-
98
-
-
84922460332
-
Delivering a disease-modifying treatment for Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2cXhs1KgtrrK, PID: 25256777
-
Godinho BM, et al. Delivering a disease-modifying treatment for Huntington’s disease. Drug Discov Today. 2015;20(1):50–64.
-
(2015)
Drug Discov Today
, vol.20
, Issue.1
, pp. 50-64
-
-
Godinho, B.M.1
-
99
-
-
84941569159
-
Therapeutic advances in Huntington’s disease
-
PID: 26226924
-
Shannon KM, Fraint A. Therapeutic advances in Huntington’s disease. Mov Disord. 2015;30(11):1539–46.
-
(2015)
Mov Disord
, vol.30
, Issue.11
, pp. 1539-1546
-
-
Shannon, K.M.1
Fraint, A.2
-
100
-
-
84918574081
-
Huntington disease: pathogenesis and treatment
-
PID: 25432725
-
Dayalu P, Albin RL. Huntington disease: pathogenesis and treatment. Neurol Clin. 2015;33(1):101–14.
-
(2015)
Neurol Clin
, vol.33
, Issue.1
, pp. 101-114
-
-
Dayalu, P.1
Albin, R.L.2
-
103
-
-
84918785958
-
H.D.I. Safety, tolerability, and efficacy of PBT2 in Huntington’s disease: a phase 2, randomised, double-blind, placebo-controlled trial
-
Huntington Study Group Reach. H.D.I. Safety, tolerability, and efficacy of PBT2 in Huntington’s disease: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2015;14(1):39–47.
-
(2015)
Lancet Neurol
, vol.14
, Issue.1
, pp. 39-47
-
-
-
104
-
-
84930012088
-
An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington’s disease
-
PID: 25223731
-
Sussmuth SD, et al. An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington’s disease. Br J Clin Pharmacol. 2015;79(3):465–76.
-
(2015)
Br J Clin Pharmacol
, vol.79
, Issue.3
, pp. 465-476
-
-
Sussmuth, S.D.1
-
107
-
-
84930189896
-
Disease modifying potential of glatiramer acetate in Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2cXhs12ku7bP, PID: 25300334
-
Corey-Bloom J, et al. Disease modifying potential of glatiramer acetate in Huntington’s disease. J Huntingtons Dis. 2014;3(3):311–6.
-
(2014)
J Huntingtons Dis
, vol.3
, Issue.3
, pp. 311-316
-
-
Corey-Bloom, J.1
-
108
-
-
80053937926
-
Neuroprotective and metabolic effects of resveratrol: therapeutic implications for Huntington’s disease and other neurodegenerative disorders
-
COI: 1:CAS:528:DC%2BC3MXht12jt7nE, PID: 21907197
-
Pasinetti GM, et al. Neuroprotective and metabolic effects of resveratrol: therapeutic implications for Huntington’s disease and other neurodegenerative disorders. Exp Neurol. 2011;232(1):1–6.
-
(2011)
Exp Neurol
, vol.232
, Issue.1
, pp. 1-6
-
-
Pasinetti, G.M.1
-
109
-
-
84938718400
-
Sirtuins: double players in Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2MXhtFKis7zF, PID: 26163995
-
Naia L, Rego AC. Sirtuins: double players in Huntington’s disease. Biochim Biophys Acta. 2015;1852(10 Pt A):2183–94.
-
(2015)
Biochim Biophys Acta
, vol.1852
, Issue.10
, pp. 2183-2194
-
-
Naia, L.1
Rego, A.C.2
-
110
-
-
0033595502
-
Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial
-
COI: 1:CAS:528:DyaK1MXmsFers7c%3D, PID: 10496259
-
Kremer B, et al. Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial. Neurology. 1999;53(5):1000–11.
-
(1999)
Neurology
, vol.53
, Issue.5
, pp. 1000-1011
-
-
Kremer, B.1
-
111
-
-
78649369122
-
A futility study of minocycline in Huntington’s disease
-
Huntington Study Group DOMINO Investigators. A futility study of minocycline in Huntington’s disease. Mov Disord. 2010;25(13):2219–24.
-
(2010)
Mov Disord
, vol.25
, Issue.13
, pp. 2219-2224
-
-
-
112
-
-
33745211255
-
Antisense oligonucleotides: from design to therapeutic application
-
COI: 1:CAS:528:DC%2BD28XlvFCmt70%3D, PID: 16700890
-
Chan JH, Lim S, Wong WS. Antisense oligonucleotides: from design to therapeutic application. Clin Exp Pharmacol Physiol. 2006;33(5–6):533–40.
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, Issue.5-6
, pp. 533-540
-
-
Chan, J.H.1
Lim, S.2
Wong, W.S.3
-
113
-
-
84901688904
-
Personalized gene silencing therapeutics for Huntington disease
-
COI: 1:CAS:528:DC%2BC2cXpsVelt7g%3D, PID: 24646433
-
Kay C, et al. Personalized gene silencing therapeutics for Huntington disease. Clin Genet. 2014;86(1):29–36.
-
(2014)
Clin Genet
, vol.86
, Issue.1
, pp. 29-36
-
-
Kay, C.1
-
114
-
-
84926687571
-
Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients
-
PID: 25207939, Article describing development of stable ASOs targeting SNPs found on a majority of mutant alleles to stop production of mhtt
-
• Skotte NH, et al. Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients. PLoS One. 2014;9(9):e107434. Article describing development of stable ASOs targeting SNPs found on a majority of mutant alleles to stop production of mhtt
-
(2014)
PLoS One
, vol.9
, Issue.9
-
-
Skotte, N.H.1
-
115
-
-
78649379362
-
Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat
-
COI: 1:CAS:528:DC%2BC3cXhtlynsb3O, PID: 21028906
-
Gagnon KT, et al. Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat. Biochemistry. 2010;49(47):10166–78.
-
(2010)
Biochemistry
, vol.49
, Issue.47
, pp. 10166-10178
-
-
Gagnon, K.T.1
-
116
-
-
70349469318
-
Allele-selective inhibition of mutant huntingtin by peptide nucleic acid-peptide conjugates, locked nucleic acid, and small interfering RNA
-
COI: 1:CAS:528:DC%2BD1MXhtlGgu7zJ, PID: 19796074
-
Hu J, Matsui M, Corey DR. Allele-selective inhibition of mutant huntingtin by peptide nucleic acid-peptide conjugates, locked nucleic acid, and small interfering RNA. Ann N Y Acad Sci. 2009;1175:24–31.
-
(2009)
Ann N Y Acad Sci
, vol.1175
, pp. 24-31
-
-
Hu, J.1
Matsui, M.2
Corey, D.R.3
-
117
-
-
84937251574
-
Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity
-
COI: 1:CAS:528:DC%2BC28XhtFOntL3K, PID: 25035419
-
Sun X, et al. Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity. Hum Mol Genet. 2014;23(23):6302–17.
-
(2014)
Hum Mol Genet
, vol.23
, Issue.23
, pp. 6302-6317
-
-
Sun, X.1
-
118
-
-
84862663712
-
Sustained therapeutic reversal of Huntington’s disease by transient repression of huntingtin synthesis
-
COI: 1:CAS:528:DC%2BC38XptVKgtbs%3D, PID: 22726834
-
Kordasiewicz HB, et al. Sustained therapeutic reversal of Huntington’s disease by transient repression of huntingtin synthesis. Neuron. 2012;74(6):1031–44.
-
(2012)
Neuron
, vol.74
, Issue.6
, pp. 1031-1044
-
-
Kordasiewicz, H.B.1
-
119
-
-
82955237522
-
Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin
-
COI: 1:CAS:528:DC%2BC3MXht1GqsLzM, PID: 21971427
-
Carroll JB, et al. Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin. Mol Ther. 2011;19(12):2178–85.
-
(2011)
Mol Ther
, vol.19
, Issue.12
, pp. 2178-2185
-
-
Carroll, J.B.1
-
120
-
-
84907924586
-
Targets for future clinical trials in Huntington’s disease: what’s in the pipeline?
-
COI: 1:CAS:528:DC%2BC2cXhsFGhtrfF, PID: 25155142
-
Wild EJ, Tabrizi SJ. Targets for future clinical trials in Huntington’s disease: what’s in the pipeline? Mov Disord. 2014;29(11):1434–45.
-
(2014)
Mov Disord
, vol.29
, Issue.11
, pp. 1434-1445
-
-
Wild, E.J.1
Tabrizi, S.J.2
-
121
-
-
84876466100
-
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
-
COI: 1:CAS:528:DC%2BC3sXltVynsrY%3D, PID: 23541756
-
Miller TM, et al. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. Lancet Neurol. 2013;12(5):435–42.
-
(2013)
Lancet Neurol
, vol.12
, Issue.5
, pp. 435-442
-
-
Miller, T.M.1
-
122
-
-
85015850311
-
Inc. Safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS-HTTRx in patients with early manifest Huntington's disease
-
Ionis Pharmaceuticals, Inc. Safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS-HTTRx in patients with early manifest Huntington's disease. Bethesda: National Library of Medicine (US); 2000. https://clinicaltrials.gov/ct2/show/NCT02519036.
-
(2000)
Bethesda: National Library of Medicine (US)
-
-
Pharmaceuticals, I.1
-
123
-
-
84907920445
-
Huntingtin-lowering strategies in Huntington’s disease: antisense oligonucleotides, small RNAs, and gene editing
-
COI: 1:CAS:528:DC%2BC2cXhsFGhtrfE, PID: 25164989, Review article describing in greater detail the function and limitations of various genetic approaches at gene silencing for HD
-
• Aronin N, DiFiglia M. Huntingtin-lowering strategies in Huntington’s disease: antisense oligonucleotides, small RNAs, and gene editing. Mov Disord. 2014;29(11):1455–61. Review article describing in greater detail the function and limitations of various genetic approaches at gene silencing for HD
-
(2014)
Mov Disord
, vol.29
, Issue.11
, pp. 1455-1461
-
-
Aronin, N.1
DiFiglia, M.2
-
124
-
-
84919622781
-
Huntington’s disease: an update of therapeutic strategies
-
COI: 1:CAS:528:DC%2BC2cXhvFantLjJ, PID: 25447911
-
Kumar A, et al. Huntington’s disease: an update of therapeutic strategies. Gene. 2015;556(2):91–7.
-
(2015)
Gene
, vol.556
, Issue.2
, pp. 91-97
-
-
Kumar, A.1
-
125
-
-
84901195245
-
Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington’s disease
-
COI: 1:CAS:528:DC%2BC2cXotlWhsrw%3D, PID: 24484067
-
Stanek LM, et al. Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington’s disease. Hum Gene Ther. 2014;25(5):461–74.
-
(2014)
Hum Gene Ther
, vol.25
, Issue.5
, pp. 461-474
-
-
Stanek, L.M.1
-
126
-
-
77953700445
-
Promising human brain tumors therapy with interference RNA intervention (iRNAi)
-
PID: 20118657
-
Rolle K, et al. Promising human brain tumors therapy with interference RNA intervention (iRNAi). Cancer Biol Ther. 2010;9(5):396–406.
-
(2010)
Cancer Biol Ther
, vol.9
, Issue.5
, pp. 396-406
-
-
Rolle, K.1
-
127
-
-
84891834550
-
Phase I clinical trial of SYL040012, a small interfering RNA targeting beta-adrenergic receptor 2, for lowering intraocular pressure
-
COI: 1:CAS:528:DC%2BC3sXhs1WmsLjE, PID: 24025752
-
Moreno-Montanes J, et al. Phase I clinical trial of SYL040012, a small interfering RNA targeting beta-adrenergic receptor 2, for lowering intraocular pressure. Mol Ther. 2014;22(1):226–32.
-
(2014)
Mol Ther
, vol.22
, Issue.1
, pp. 226-232
-
-
Moreno-Montanes, J.1
-
128
-
-
84868538087
-
Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice
-
COI: 1:CAS:528:DC%2BC38Xhslyiu7fP, PID: 23054839
-
Garriga-Canut M, et al. Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice. Proc Natl Acad Sci. 2012;109(45):E3136–45.
-
(2012)
Proc Natl Acad Sci
, vol.109
, Issue.45
, pp. E3136-E3145
-
-
Garriga-Canut, M.1
|