Deep brain stimulation for Huntington's disease: Long-term results of a prospective open-label study: Clinical article

Journal of Neurosurgery

Volumn 121, Issue 1, 2014, Pages 114-122

  Gonzalez, Victoria ^a,b,c   Cif, Laura ^a,b,c   Biolsi, Brigitte ^a,b,c   Garcia Ptacek, Sara ^a,c,d   Seychelles, Anne ^a,b,c   Sanrey, Emily ^a,c   Descours, Irene ^c,e   Coubes, Christine ^c,e   Ribeiro De Moura, Ana Maria ^a,c   Corlobe, Astrid ^c,e   James, Syril ^a,b,c   Roujeau, Thomas ^a,b,c   Coubes, Philippe ^a,b,c  

^a GUI DE CHAULIAC HOSPITAL   (France)

^b INSERM   (France)

^c UNIV MONTPELLIER   (France)

^d KAROLINSKA INSTITUTE   (Sweden)

^e MONTPELLIER UNIVERSITY HOSPITAL   (France)

Author keywords

Bradykinesia; Chorea; Deep brain stimulation; Functional neurosurgery; Globus pallidus internus; Huntington's disease

Indexed keywords

ALPRAZOLAM; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CLONAZEPAM; CYAMEMAZINE; ESCITALOPRAM; HYDROXYZINE; LEVODOPA; LORMETAZEPAM; NEUROLEPTIC AGENT; OLANZAPINE; PAROXETINE; PIPOTIAZINE; RISPERIDONE; TETRABENAZINE; TIANEPTINE; TIAPRIDE; VALPROIC ACID; VENLAFAXINE; ZOPICLONE;

ADULT; AGGRESSION; ARTICLE; AUTOMUTILATION; BEHAVIOR DISORDER; BRADYKINESIA; BRAIN DEPTH STIMULATION; CEREBELLAR STIMULATOR; CLINICAL ARTICLE; CLINICAL TRIAL; DEPTH ELECTRODE; DISEASE COURSE; DRUG DOSE INCREASE; DYSTONIA; FEMALE; FOLLOW UP; FUNCTIONAL DISEASE; GLOBUS PALLIDUS; GLOBUS PALLIDUS INTERNUS; HUMAN; HUNTINGTON CHOREA; IMPLANTABLE PULSE GENERATOR; LEG CRAMP; MALE; MIDDLE AGED; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; SELF DEFENESTRATION; THERAPY EFFECT; TREATMENT RESPONSE; UNIFIED HUNTINGTON DISEASE RATING SCALE;

BRADYKINESIA; CHOREA; DBS = DEEP BRAIN STIMULATION; DEEP BRAIN STIMULATION; DRS = DEMENTIA RATING SCALE; FA = FUNCTIONAL ASSESSMENT; FUNCTIONAL NEUROSURGERY; GLOBUS PALLIDUS INTERNUS; GPI = GLOBUS PALLIDUS INTERNUS; HD = HUNTINGTON'S DISEASE; HR-QOL = HEALTH-RELATED QUALITY OF LIFE; HUNTINGTON'S DISEASE; IPG = IMPLANTABLE PULSE GENERATOR; IS = INDEPENDENCE SCALE; TFC = TOTAL FUNCTIONAL CAPACITY; UHDRS = UNIFIED HUNTINGTON'S DISEASE RATING SCALE;

ADULT; AGED; CHOREA; DEEP BRAIN STIMULATION; FEMALE; GLOBUS PALLIDUS; HUMANS; HUNTINGTON DISEASE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84903892559     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.2.JNS131722     Document Type: Article

References (42)

1. Adam OR, Jankovic J: Symptomatic treatment of Huntington disease. Neurotherapeutics 5:181-197, 2008 (Pubitemid 351446213)
2. Banaszkiewicz K, Sitek EJ, Rudzińska M, Sołtan W, Sławek J, Szczudlik A: Huntington's disease from the patient, caregiver and physician's perspectives: three sides of the same coin? J Neural Transm 119:1361-1365, 2012
3. Berardelli A, Noth J, Thompson PD, Bollen EL, Currà A, Deuschl G, et al: Pathophysiology of chorea and bradykinesia in Huntington's disease. Mov Disord 14:398-403, 1999 (Pubitemid 30011648)
4. Biolsi B, Cif L, Fertit HE, Robles SG, Coubes P: Long-term follow-up of Huntington disease treated by bilateral deep brain stimulation of the internal globus pallidus. Case report. J Neurosurg 109:130-132, 2008 (Pubitemid 351930532)
5. Bonelli RM, Wenning GK: Pharmacological management of Huntington's disease: an evidence-based review. Curr Pharm Des 12:2701-2720, 2006
6. Cif L, Ruge D, Gonzalez V, Limousin P, Vasques X, Hariz MI, et al: The influence of deep brain stimulation intensity and duration on symptoms evolution in an OFF stimulation dystonia study. Brain Stimul 6:500-505, 2012
7. Coubes P, Vayssiere N, El Fertit H, Hemm S, Cif L, Kienlen J, et al: Deep brain stimulation for dystonia. Surgical technique. Stereotact Funct Neurosurg 78:183-191, 2002 (Pubitemid 36351218)
8. Cubo E, Shannon KM, Penn RD, Kroin JS: Internal globus pallidotomy in dystonia secondary to Huntington's disease. Mov Disord 15:1248-1251, 2000
9. Fasano A, Mazzone P, Piano C, Quaranta D, Soleti F, Bentivoglio AR: GPi-DBS in Huntington's disease: results on motor function and cognition in a 72-year-old case. Mov Disord 23: 1289-1292, 2008
10. Frank S: Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. BMC Neurol 9:62, 2009 (Erratum in BMC Neurol 11:18, 2011)
11. Gamez J, Lorenzo-Bosquet C, Cuberas-Borrós G, Carmona F, Hernández-Vara J, Castilló J, et al: Does reduced [(123)I]-FPCIT binding in Huntington's disease suggest pre-synaptic dopaminergic involvement? Clin Neurol Neurosurg 112:870-875, 2010
12. García Ruiz PJ, Hernández J, Cantarero S, Bartolomé M, Sánchez Bernardos V, García de Yébenez J: Bradykinesia in Huntington's disease. A prospective, follow-up study. J Neurol 249:437-440, 2002
13. Ginovart N, Lundin A, Farde L, Halldin C, Bäckman L, Swahn CG, et al: PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease. Brain 120:503-514, 1997 (Pubitemid 27153642)
14. Grabli D, Ewenczyk C, Coelho-Braga MC, Lagrange C, Fraix V, Cornu P, et al: Interruption of deep brain stimulation of the globus pallidus in primary generalized dystonia. Mov Disord 24:2363-2369, 2009
15. Grips E, Blahak C, Capelle HH, Bäzner H, Weigel R, Sedlaczek O, et al: Patterns of reoccurrence of segmental dystonia after discontinuation of deep brain stimulation. J Neurol Neurosurg Psychiatry 78:318-320, 2007 (Pubitemid 46579675)
16. Hebb MO, Chiasson P, Lang AE, Brownstone RM, Mendez I: Sustained relief of dystonia following cessation of deep brain stimulation. Mov Disord 22:1958-1962, 2007 (Pubitemid 350134212)
17. Hebb MO, Garcia R, Gaudet P, Mendez IM: Bilateral stimulation of the globus pallidus internus to treat choreathetosis in Huntington's disease: technical case report. Neurosurgery 58: E383, 2006
18. Helder DI, Kaptein AA, van Kempen GM, van Houwelingen JC, Roos RA: Impact of Huntington's disease on quality of life. Mov Disord 16:325-330, 2001 (Pubitemid 36061169)
19. Ho AK, Gilbert AS, Mason SL, Goodman AO, Barker RA: Health-related quality of life in Huntington's disease: which factors matter most? Mov Disord 24:574-578, 2009
20. Ho AK, Hocaoglu MB, European Huntington's Disease Network Quality of Life Working Group: Impact of Huntington's across the entire disease spectrum: the phases and stages of disease from the patient perspective. Clin Genet 80:235-239, 2011
21. Hocaoglu MB, Gaffan EA, Ho AK: Health-related quality of life in Huntington's disease patients: a comparison of proxy assessment and patient self-rating using the disease-specific Huntington's disease health-related quality of life questionnaire (HDQoL). J Neurol 259:1793-1800, 2012
22. Hocaoglu MB, Gaffan EA, Ho AK: The Huntington's Disease health-related Quality of Life questionnaire (HDQoL): a disease-specific measure of health-related quality of life. Clin Genet 81:117-122, 2012
23. Huntington Study Group: Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. Neurology 66:366-372, 2006
24. Huntington Study Group: Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 11:136-142, 1996
25. Jongen PJ, Renier WO, Gabreëls FJ: Seven cases of Huntington's disease in childhood and levodopa induced improvement in the hypokinetic - rigid form. Clin Neurol Neurosurg 82: 251-261, 1980 (Pubitemid 11100926)
26. Kang GA, Heath S, Rothlind J, Starr PA: Long-term follow-up of pallidal deep brain stimulation in two cases of Huntington's disease. J Neurol Neurosurg Psychiatry 82:272-277, 2011
27. Mestre TA, Ferreira JJ: An evidence-based approach in the treatment of Huntington's disease. Parkinsonism Relat Disord 18:316-320, 2012
28. Moro E, Lang AE, Strafella AP, Poon YY, Arango PM, Dagher A, et al: Bilateral globus pallidus stimulation for Huntington's disease. Ann Neurol 56:290-294, 2004 (Pubitemid 39037926)
29. Paulsen JS, Nehl C, Hoth KF, Kanz JE, Benjamin M, Conybeare R, et al: Depression and stages of Huntington's disease. J Neuropsychiatry Clin Neurosci 17:496-502, 2005 (Pubitemid 41790050)
30. Racette BA, Perlmutter JS: Levodopa responsive parkinsonism in an adult with Huntington's disease. J Neurol Neurosurg Psychiatry 65:577-579, 1998 (Pubitemid 28438897)
31. Ready RE, Mathews M, Leserman A, Paulsen JS: Patient and caregiver quality of life in Huntington's disease. Mov Disord 23:721-726, 2008
32. Reuter I, Hu MT, Andrews TC, Brooks DJ, Clough C, Chaudhuri KR: Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome. J Neurol Neurosurg Psychiatry 68:238-241, 2000 (Pubitemid 30245854)
33. Rosenblatt A, Kumar BV, Margolis RL, Welsh CS, Ross CA: Factors contributing to institutionalization in patients with Huntington's disease. Mov Disord 26:1711-1716, 2011
34. Ross CA, Tabrizi SJ: Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10:83-98, 2011
35. Shoulson I, Fahn S: Huntington disease: clinical care and evaluation. Neurology 29:1-3, 1979 (Pubitemid 9051179)
36. Spiegel EA, Wycis HT: Thalamotomy and pallidotomy for treatment of choreic movements. Acta Neurochir (Wien) 2: 417-422, 1952
37. Suzuki M, Desmond TJ, Albin RL, Frey KA: Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers. Synapse 41:329-336, 2001 (Pubitemid 32702253)
38. Thompson PD, Berardelli A, Rothwell JC, Day BL, Dick JP, Benecke R, et al: The coexistence of bradykinesia and chorea in Huntington's disease and its implications for theories of basal ganglia control of movement. Brain 111:223-244, 1988
39. Velez-Lago FM, Thompson A, Oyama G, Hardwick A, Sporrer JM, Zeilman P, et al: Differential and better response to deep brain stimulation of chorea compared to dystonia in Huntington's disease. Stereotact Funct Neurosurg 91:129-133, 2013
40. Venuto CS, McGarry A, Ma Q, Kieburtz K: Pharmacologic approaches to the treatment of Huntington's disease. Mov Disord 27:31-41, 2012
41. Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP Jr: Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol 44:559-577, 1985 (Pubitemid 16196286)
42. Wheelock VL, Tempkin T, Marder K, Nance M, Myers RH, Zhao H, et al: Predictors of nursing home placement in Huntington disease. Neurology 60:998-1001, 2003 (Pubitemid 36348935)