-
1
-
-
76749157903
-
Advances in the treatment of malignant gliomas
-
COI: 1:CAS:528:DC%2BC3cXht1Cjsb7K, PID: 20425605
-
Khasraw M, Lassman AB. Advances in the treatment of malignant gliomas. Curr Oncol Rep. 2010;12(1):26–33. doi:10.1007/s11912-009-0077-4.
-
(2010)
Curr Oncol Rep
, vol.12
, Issue.1
, pp. 26-33
-
-
Khasraw, M.1
Lassman, A.B.2
-
2
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
COI: 1:CAS:528:DC%2BD1MXlsVKhs74%3D, PID: 19269895
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459–66. doi:10.1016/s1470-2045(09)70025-7.
-
(2009)
Lancet Oncol
, vol.10
, Issue.5
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
-
3
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–74. doi:10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
-
COI: 1:CAS:528:DC%2BC2MXkvVWgsLk%3D, PID: 25795410
-
Weber JS, D’Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2015;16(4):375–84. doi:10.1016/s1470-2045(15)70076-8.
-
(2015)
Lancet Oncol
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D’Angelo, S.P.2
Minor, D.3
Hodi, F.S.4
Gutzmer, R.5
Neyns, B.6
-
6
-
-
84929572937
-
Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial
-
COI: 1:CAS:528:DC%2BC2MXpvFahsbY%3D
-
Motzer RJ, Rini BI, McDermott DF, Redman BG, Kuzel TM, Harrison MR, et al. Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial. J Clin Oncol Off J Am Soc Clin Oncol. 2015;33(13):1430–7. doi:10.1200/jco.2014.59.0703.
-
(2015)
J Clin Oncol Off J Am Soc Clin Oncol
, vol.33
, Issue.13
, pp. 1430-1437
-
-
Motzer, R.J.1
Rini, B.I.2
McDermott, D.F.3
Redman, B.G.4
Kuzel, T.M.5
Harrison, M.R.6
-
7
-
-
84891373595
-
Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial
-
COI: 1:CAS:528:DC%2BC3sXitVWjtL3K, PID: 24332512
-
Westin JR, Chu F, Zhang M, Fayad LE, Kwak LW, Fowler N, et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014;15(1):69–77. doi:10.1016/s1470-2045(13)70551-5.
-
(2014)
Lancet Oncol
, vol.15
, Issue.1
, pp. 69-77
-
-
Westin, J.R.1
Chu, F.2
Zhang, M.3
Fayad, L.E.4
Kwak, L.W.5
Fowler, N.6
-
8
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
COI: 1:CAS:528:DC%2BC3sXht1emsbjP, PID: 23724846
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2):134–44. doi:10.1056/NEJMoa1305133.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
9
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
COI: 1:CAS:528:DC%2BC28XjsFyitL0%3D, PID: 26412456
-
Borghaei H, Paz-Ares L, Horn L, Spigel DR, Steins M, Ready NE, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 2015;373(17):1627–39. doi:10.1056/NEJMoa1507643.
-
(2015)
N Engl J Med
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
Spigel, D.R.4
Steins, M.5
Ready, N.E.6
-
10
-
-
84924901863
-
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial
-
COI: 1:CAS:528:DC%2BC2MXjtFShs7s%3D, PID: 25704439
-
Rizvi NA, Mazieres J, Planchard D, Stinchcombe TE, Dy GK, Antonia SJ, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16(3):257–65. doi:10.1016/s1470-2045(15)70054-9.
-
(2015)
Lancet Oncol
, vol.16
, Issue.3
, pp. 257-265
-
-
Rizvi, N.A.1
Mazieres, J.2
Planchard, D.3
Stinchcombe, T.E.4
Dy, G.K.5
Antonia, S.J.6
-
11
-
-
84960407098
-
PD-L1 expression and prognostic impact in glioblastoma
-
Nduom EK, Wei J, Yaghi NK, Huang N, Kong L-Y, Gabrusiewicz K, et al. ;18(2):195–205. doi:. This study demonstrates the rates of PD-L1 expression in glioblastoma, which is increasingly used for eligibility criteria in clinical trials
-
Nduom EK, Wei J, Yaghi NK, Huang N, Kong L-Y, Gabrusiewicz K, et al. PD-L1 expression and prognostic impact in glioblastoma. J Neuro-Oncol. 2016;18(2):195–205. doi:10.1093/neuonc/nov172. This study demonstrates the rates of PD-L1 expression in glioblastoma, which is increasingly used for eligibility criteria in clinical trials.
-
(2016)
J Neuro-Oncol
-
-
-
12
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
COI: 1:CAS:528:DC%2BC38Xht1Wkt7fN, PID: 22903150
-
Ransohoff RM, Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol. 2012;12(9):623–35. doi:10.1038/nri3265.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.9
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
13
-
-
0017864016
-
Relationship of lymphocyte invasion and survival of brain tumor patients
-
COI: 1:STN:280:DyaE1M%2FmtVyrtQ%3D%3D, PID: 718133
-
Brooks WH, Markesbery WR, Gupta GD, Roszman TL. Relationship of lymphocyte invasion and survival of brain tumor patients. Ann Neurol. 1978;4(3):219–24. doi:10.1002/ana.410040305.
-
(1978)
Ann Neurol
, vol.4
, Issue.3
, pp. 219-224
-
-
Brooks, W.H.1
Markesbery, W.R.2
Gupta, G.D.3
Roszman, T.L.4
-
14
-
-
0021151540
-
Mononuclear infiltrates in human intracranial tumors as a prognostic factor. Influence of preoperative steroid treatment. I. Glioblastoma
-
COI: 1:STN:280:DyaL2M%2Fgt1CgtQ%3D%3D, PID: 6478676
-
Boker DK, Kalff R, Gullotta F, Weekes-Seifert S, Mohrer U. Mononuclear infiltrates in human intracranial tumors as a prognostic factor. Influence of preoperative steroid treatment. I. Glioblastoma. Clin Neuropathol. 1984;3(4):143–7.
-
(1984)
Clin Neuropathol
, vol.3
, Issue.4
, pp. 143-147
-
-
Boker, D.K.1
Kalff, R.2
Gullotta, F.3
Weekes-Seifert, S.4
Mohrer, U.5
-
15
-
-
0018068743
-
Lymphocytic infiltrates in primary glioblastomas and recidivous gliomas. Incidence, fate, and relevance to prognosis in 228 operated cases
-
COI: 1:STN:280:DyaE1M%2FptVehsw%3D%3D, PID: 731302
-
Palma L, Di Lorenzo N, Guidetti B. Lymphocytic infiltrates in primary glioblastomas and recidivous gliomas. Incidence, fate, and relevance to prognosis in 228 operated cases. J Neurosurg. 1978;49(6):854–61. doi:10.3171/jns.1978.49.6.0854.
-
(1978)
J Neurosurg
, vol.49
, Issue.6
, pp. 854-861
-
-
Palma, L.1
Di Lorenzo, N.2
Guidetti, B.3
-
16
-
-
0024338056
-
The mononuclear cell infiltrate compared with survival in high-grade astrocytomas
-
COI: 1:STN:280:DyaL1MzhvFGrsw%3D%3D, PID: 2750489
-
Rossi ML, Jones NR, Candy E, Nicoll JA, Compton JS, Hughes JT, et al. The mononuclear cell infiltrate compared with survival in high-grade astrocytomas. Acta Neuropathol. 1989;78(2):189–93.
-
(1989)
Acta Neuropathol
, vol.78
, Issue.2
, pp. 189-193
-
-
Rossi, M.L.1
Jones, N.R.2
Candy, E.3
Nicoll, J.A.4
Compton, J.S.5
Hughes, J.T.6
-
17
-
-
0021906674
-
Prognostic value of round cell (lymphocyte) infiltration in malignant gliomas
-
COI: 1:STN:280:DyaL2M7kt1Onsw%3D%3D, PID: 2983448
-
Safdari H, Hochberg FH, Richardson Jr EP. Prognostic value of round cell (lymphocyte) infiltration in malignant gliomas. Surg Neurol. 1985;23(3):221–6.
-
(1985)
Surg Neurol
, vol.23
, Issue.3
, pp. 221-226
-
-
Safdari, H.1
Hochberg, F.H.2
Richardson, E.P.3
-
18
-
-
84900527836
-
Tumour-infiltrating CD4(+) and CD8(+) lymphocytes as predictors of clinical outcome in glioma
-
Han S, Zhang C, Li Q, Dong J, Liu Y, Huang Y, et al. ;110(10):2560–8. This paper is important in revealing different populations of TILs which may correlate with prognosis
-
Han S, Zhang C, Li Q, Dong J, Liu Y, Huang Y, et al. Tumour-infiltrating CD4(+) and CD8(+) lymphocytes as predictors of clinical outcome in glioma. Br J Cancer. 2014;110(10):2560–8. doi:10.1038/bjc.2014.162. This paper is important in revealing different populations of TILs which may correlate with prognosis.
-
(2014)
Br J Cancer
-
-
-
19
-
-
52649169692
-
Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas
-
COI: 1:CAS:528:DC%2BD1cXpslKgurw%3D, PID: 18698034
-
Heimberger AB, Abou-Ghazal M, Reina-Ortiz C, Yang DS, Sun W, Qiao W, et al. Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas. Clin Cancer Res. 2008;14(16):5166–72. doi:10.1158/1078-0432.ccr-08-0320.
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.16
, pp. 5166-5172
-
-
Heimberger, A.B.1
Abou-Ghazal, M.2
Reina-Ortiz, C.3
Yang, D.S.4
Sun, W.5
Qiao, W.6
-
20
-
-
33748481603
-
An increase in CD4 + CD25 + FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
-
PID: 16723631
-
El Andaloussi A, Lesniak MS. An increase in CD4 + CD25 + FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme. Neuro-Oncology. 2006;8(3):234–43. doi:10.1215/15228517-2006-006.
-
(2006)
Neuro-Oncology
, vol.8
, Issue.3
, pp. 234-243
-
-
El Andaloussi, A.1
Lesniak, M.S.2
-
21
-
-
84991396048
-
Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies
-
PID: 27370400
-
Garber ST, Hashimoto Y, Weathers SP, Xiu J, Gatalica Z, Verhaak RG, et al. Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies. Neuro-Oncology. 2016. doi:10.1093/neuonc/now132.
-
(2016)
Neuro-Oncology
-
-
Garber, S.T.1
Hashimoto, Y.2
Weathers, S.P.3
Xiu, J.4
Gatalica, Z.5
Verhaak, R.G.6
-
22
-
-
84963621254
-
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
-
COI: 1:CAS:528:DC%2BC28XmtVOrurc%3D, PID: 27079802
-
Topalian SL, Taube JM, Anders RA, Pardoll DM. Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy. Nat Rev Cancer. 2016;16(5):275–87. doi:10.1038/nrc.2016.36.
-
(2016)
Nat Rev Cancer
, vol.16
, Issue.5
, pp. 275-287
-
-
Topalian, S.L.1
Taube, J.M.2
Anders, R.A.3
Pardoll, D.M.4
-
23
-
-
84879484111
-
Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages
-
COI: 1:CAS:528:DC%2BC3sXpsVyns7o%3D, PID: 23613317
-
Bloch O, Crane CA, Kaur R, Safaee M, Rutkowski MJ, Parsa AT. Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages. Clin Cancer Res. 2013;19(12):3165–75. doi:10.1158/1078-0432.ccr-12-3314.
-
(2013)
Clin. Cancer Res
, vol.19
, Issue.12
, pp. 3165-3175
-
-
Bloch, O.1
Crane, C.A.2
Kaur, R.3
Safaee, M.4
Rutkowski, M.J.5
Parsa, A.T.6
-
24
-
-
84943241524
-
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma
-
PID: 25355681
-
Berghoff AS, Kiesel B, Widhalm G, Rajky O, Ricken G, Wohrer A, et al. Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma. Neuro-Oncology. 2015;17(8):1064–75. doi:10.1093/neuonc/nou307.
-
(2015)
Neuro-Oncology
, vol.17
, Issue.8
, pp. 1064-1075
-
-
Berghoff, A.S.1
Kiesel, B.2
Widhalm, G.3
Rajky, O.4
Ricken, G.5
Wohrer, A.6
-
25
-
-
84962032646
-
Glioblastoma eradication following immune checkpoint blockade in an orthotopic, immunocompetent model
-
COI: 1:CAS:528:DC%2BC28Xit1Kqsr0%3D, PID: 26546453
-
Reardon DA, Gokhale PC, Klein SR, Ligon KL, Rodig SJ, Ramkissoon SH, et al. Glioblastoma eradication following immune checkpoint blockade in an orthotopic, immunocompetent model. Cancer Immunol Res. 2016;4(2):124–35. doi:10.1158/2326-6066.cir-15-0151.
-
(2016)
Cancer Immunol Res
, vol.4
, Issue.2
, pp. 124-135
-
-
Reardon, D.A.1
Gokhale, P.C.2
Klein, S.R.3
Ligon, K.L.4
Rodig, S.J.5
Ramkissoon, S.H.6
-
26
-
-
84904061991
-
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
-
COI: 1:CAS:528:DC%2BC2cXhslKnsr%2FK, PID: 24691018
-
Wainwright DA, Chang AL, Dey M, Balyasnikova IV, Kim CK, Tobias A, et al. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res. 2014;20(20):5290–301. doi:10.1158/1078-0432.ccr-14-0514.
-
(2014)
Clin. Cancer Res
, vol.20
, Issue.20
, pp. 5290-5301
-
-
Wainwright, D.A.1
Chang, A.L.2
Dey, M.3
Balyasnikova, I.V.4
Kim, C.K.5
Tobias, A.6
-
27
-
-
34247502076
-
Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function
-
COI: 1:CAS:528:DC%2BD2sXjs12rtL8%3D, PID: 17404100
-
Fecci PE, Ochiai H, Mitchell DA, Grossi PM, Sweeney AE, Archer GE, et al. Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function. Clin Cancer Res. 2007;13(7):2158–67. doi:10.1158/1078-0432.ccr-06-2070.
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.7
, pp. 2158-2167
-
-
Fecci, P.E.1
Ochiai, H.2
Mitchell, D.A.3
Grossi, P.M.4
Sweeney, A.E.5
Archer, G.E.6
-
28
-
-
84890846323
-
Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection
-
vom Berg J, Vrohlings M, Haller S, Haimovici A, Kulig P, Sledzinska A, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J Exp Med. 2013;210(13):2803–11. doi:10.1084/jem.20130678.
-
(2013)
J Exp Med
, vol.210
, Issue.13
, pp. 2803-2811
-
-
vom Berg, J.1
Vrohlings, M.2
Haller, S.3
Haimovici, A.4
Kulig, P.5
Sledzinska, A.6
-
29
-
-
84861233216
-
Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors
-
COI: 1:CAS:528:DC%2BC38Xnt1elt74%3D
-
Agarwalla P, Barnard Z, Fecci P, Dranoff G, Curry Jr WT. Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. J Immunother (Hagerstown, Md: 1997). 2012;35(5):385–9. doi:10.1097/CJI.0b013e3182562d59.
-
(2012)
J. Immunother (Hagerstown, Md: 1997)
, vol.35
, Issue.5
, pp. 385-389
-
-
Agarwalla, P.1
Barnard, Z.2
Fecci, P.3
Dranoff, G.4
Curry, W.T.5
-
30
-
-
84877581852
-
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
-
COI: 1:CAS:528:DC%2BC3sXivFyku7k%3D, PID: 23462419
-
Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys. 2013;86(2):343–9. doi:10.1016/j.ijrobp.2012.12.025.
-
(2013)
Int J Radiat Oncol Biol Phys
, vol.86
, Issue.2
, pp. 343-349
-
-
Zeng, J.1
See, A.P.2
Phallen, J.3
Jackson, C.M.4
Belcaid, Z.5
Ruzevick, J.6
-
31
-
-
84969610644
-
Prioritization schema for immunotherapy clinical trials in glioblastoma
-
Hodges TR, Ferguson SD, Caruso HG, Kohanbash G, Zhou S, Cloughesy TF et al. (just-accepted):00
-
Hodges TR, Ferguson SD, Caruso HG, Kohanbash G, Zhou S, Cloughesy TF et al. Prioritization schema for immunotherapy clinical trials in glioblastoma. OncoImmunology. 2016 (just-accepted):00-.
-
(2016)
OncoImmunology
-
-
-
32
-
-
84937515352
-
Re-defining response and treatment effects for neuro-oncology immunotherapy clinical trials
-
COI: 1:CAS:528:DC%2BC2MXjsVGhu7k%3D
-
Reardon DA, Okada H. Re-defining response and treatment effects for neuro-oncology immunotherapy clinical trials. J Neuro-Oncol. 2015;123(3):339–46. doi:10.1007/s11060-015-1748-7.
-
(2015)
J Neuro-Oncol
, vol.123
, Issue.3
, pp. 339-346
-
-
Reardon, D.A.1
Okada, H.2
-
33
-
-
84976878200
-
Pembrolizumab: first experience with recurrent primary central nervous system (CNS) tumors
-
PID: 27663387
-
Blumenthal DT, Yalon M, Vainer GW, Lossos A, Yust S, Tzach L, et al. Pembrolizumab: first experience with recurrent primary central nervous system (CNS) tumors. J Neuro-Oncol. 2016. doi:10.1007/s11060-016-2190-1.
-
(2016)
J Neuro-Oncol
-
-
Blumenthal, D.T.1
Yalon, M.2
Vainer, G.W.3
Lossos, A.4
Yust, S.5
Tzach, L.6
-
35
-
-
85015796571
-
ET-53 ipilimumab for recurrent glioblastoma (GBM)
-
Schaff LR, Lassman AB, Goldlust SA, Cloughesy T, Singer S, Schwartz GK, et al. ET-53 ipilimumab for recurrent glioblastoma (GBM). Neuro-Oncology. 2014;16 suppl 5:v90. doi:10.1093/neuonc/nou255.50.
-
(2014)
Neuro-Oncology
, vol.16
, pp. v90
-
-
Schaff, L.R.1
Lassman, A.B.2
Goldlust, S.A.3
Cloughesy, T.4
Singer, S.5
Schwartz, G.K.6
-
36
-
-
84907651089
-
IT-13Ipilimumab for recurrent high-grade glioma: a single-institution case series
-
Hu J, Yu J, Black K, Rudnick J. IT-13Ipilimumab for recurrent high-grade glioma: a single-institution case series. Neuro-Oncology. 2014;16 suppl 5:v112. doi:10.1093/neuonc/nou258.11.
-
(2014)
Neuro-Oncology
, vol.16
, pp. v112
-
-
Hu, J.1
Yu, J.2
Black, K.3
Rudnick, J.4
-
37
-
-
84992103934
-
Sequential immune checkpoint inhibition with concurrent bevacizumab for relapsed glioblastoma: a single centre experience
-
Brown NF, Carter T, Shaw HM, Cohn-Brown D, Chester K, Mulholland PJ, et al. Sequential immune checkpoint inhibition with concurrent bevacizumab for relapsed glioblastoma: a single centre experience. ASCO Meeting Abs. 2016;34:e13514.
-
(2016)
ASCO Meeting Abs
, vol.34
-
-
Brown, N.F.1
Carter, T.2
Shaw, H.M.3
Cohn-Brown, D.4
Chester, K.5
Mulholland, P.J.6
-
38
-
-
84976467739
-
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
-
This report of two pediatric patients with extraordinary high mutational loads responding to nivolumab suggests the hypermutator phenotype may be sensitive to immune checkpoint inhibitors
-
Bouffet E, Larouche V, Campbell BB, Merico D, de Borja R, Aronson M, et al. Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency. J Clin Oncol Off J Am Soc Clin Oncol. 2016. doi:10.1200/jco.2016.66.6552. This report of two pediatric patients with extraordinary high mutational loads responding to nivolumab suggests the hypermutator phenotype may be sensitive to immune checkpoint inhibitors.
-
(2016)
J Clin Oncol Off J Am Soc Clin Oncol
-
-
Bouffet, E.1
Larouche, V.2
Campbell, B.B.3
Merico, D.4
de Borja, R.5
Aronson, M.6
-
39
-
-
84860446616
-
Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial
-
COI: 1:CAS:528:DC%2BC38Xmslyhsb4%3D, PID: 22456429
-
Margolin K, Ernstoff MS, Hamid O, Lawrence D, McDermott D, Puzanov I, et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol. 2012;13(5):459–65. doi:10.1016/s1470-2045(12)70090-6.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 459-465
-
-
Margolin, K.1
Ernstoff, M.S.2
Hamid, O.3
Lawrence, D.4
McDermott, D.5
Puzanov, I.6
-
40
-
-
84971619894
-
Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial
-
COI: 1:CAS:528:DC%2BC28XhtFSitrnO, PID: 27267608
-
Goldberg SB, Gettinger SN, Mahajan A, Chiang AC, Herbst RS, Sznol M, et al. Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial. Lancet Oncol. 2016;17(7):976–83. doi:10.1016/s1470-2045(16)30053-5.
-
(2016)
Lancet Oncol
, vol.17
, Issue.7
, pp. 976-983
-
-
Goldberg, S.B.1
Gettinger, S.N.2
Mahajan, A.3
Chiang, A.C.4
Herbst, R.S.5
Sznol, M.6
-
41
-
-
85015764131
-
Randomized phase IIb study of nivolumab (anti-PD-1; BMS-936558, ONO-4538) alone or in combination with ipilimumab versus bevacizumab in patients (pts) with recurrent glioblastoma (GBM)
-
Sampson JH, Vlahovic G, Desjardins A, Friedman HS, Baehring JM, Hafler D et al. ;32(15_suppl):TPS2101
-
Sampson JH, Vlahovic G, Desjardins A, Friedman HS, Baehring JM, Hafler D et al. Randomized phase IIb study of nivolumab (anti-PD-1; BMS-936558, ONO-4538) alone or in combination with ipilimumab versus bevacizumab in patients (pts) with recurrent glioblastoma (GBM). ASCO Meeting Abstracts. 2014;32(15_suppl):TPS2101.
-
(2014)
ASCO Meeting Abstracts
-
-
-
42
-
-
84947509509
-
Preliminary safety and activity of nivolumab and its combination with ipilimumab in recurrent glioblastoma (GBM): CHECKMATE-143
-
Sampson JH, Vlahovic G, Sahebjam S, Omuro AMP, Baehring JM, Hafler DA et al. Preliminary safety and activity of nivolumab and its combination with ipilimumab in recurrent glioblastoma (GBM): CHECKMATE-143. ASCO Meeting Abstracts. 2015;33(15_suppl):3010.
-
(2015)
ASCO Meeting Abstracts
, vol.33
, pp. 3010
-
-
Sampson, J.H.1
Vlahovic, G.2
Sahebjam, S.3
Omuro, A.M.P.4
Baehring, J.M.5
Hafler, D.A.6
-
43
-
-
85007574463
-
Safety and activity of nivolumab (nivo) monotherapy and nivo in combination with ipilimumab (ipi) in recurrent glioblastoma (GBM): Updated results from checkmate-143
-
Reardon DA, Sampson JH, Sahebjam S, Lim M, Baehring JM, Vlahovic G et al. Safety and activity of nivolumab (nivo) monotherapy and nivo in combination with ipilimumab (ipi) in recurrent glioblastoma (GBM): Updated results from checkmate-143. ASCO Meeting Abstracts. 2016;34(15_suppl):2014.
-
(2016)
ASCO Meeting Abstracts
, vol.34
, pp. 2014
-
-
Reardon, D.A.1
Sampson, J.H.2
Sahebjam, S.3
Lim, M.4
Baehring, J.M.5
Vlahovic, G.6
-
44
-
-
85007602636
-
EORTC 26101 phase III trial exploring the combination of bevacizumab and lomustine in patients with first progression of a glioblastoma
-
Wick W, Brandes AA, Gorlia T, Bendszus M, Sahm F, Taal W et al. EORTC 26101 phase III trial exploring the combination of bevacizumab and lomustine in patients with first progression of a glioblastoma. ASCO Meeting Abstracts. 2016;34(15_suppl):2001.
-
(2016)
ASCO Meeting Abstracts
, vol.34
, pp. 2001
-
-
Wick, W.1
Brandes, A.A.2
Gorlia, T.3
Bendszus, M.4
Sahm, F.5
Taal, W.6
-
45
-
-
84947485465
-
ReACT: Overall survival from a randomized phase II study of rindopepimut (CDX-110) plus bevacizumab in relapsed glioblastoma
-
Reardon DA, Schuster J, Tran DD, Fink KL, Nabors LB, Li G et al. ReACT: Overall survival from a randomized phase II study of rindopepimut (CDX-110) plus bevacizumab in relapsed glioblastoma. ASCO Meeting Abstracts. 2015;33(15_suppl):2009.
-
(2015)
ASCO Meeting Abstracts
, vol.33
, pp. 2009
-
-
Reardon, D.A.1
Schuster, J.2
Tran, D.D.3
Fink, K.L.4
Nabors, L.B.5
Li, G.6
-
46
-
-
85007606433
-
Safety of pembrolizumab in combination with bevacizumab in recurrent glioblastoma (rGBM)
-
Reardon DA, De Groot JF, Colman H, Jordan JT, Daras M, Clarke JL et al. Safety of pembrolizumab in combination with bevacizumab in recurrent glioblastoma (rGBM). ASCO Meeting Abstracts. 2016;34(15_suppl):2010.
-
(2016)
ASCO Meeting Abstracts
, vol.34
, pp. 2010
-
-
Reardon, D.A.1
De Groot, J.F.2
Colman, H.3
Jordan, J.T.4
Daras, M.5
Clarke, J.L.6
-
47
-
-
85015722371
-
Phase 2 study to evaluate the clinical efficacy and safety of MEDI4736 (durvalumab) in patients with glioblastoma (GBM)
-
Reardon DA, Kaley TJ, Dietrich J, Lim M, Dunn GP, Gan HK et al. 34(15_suppl):TPS2080
-
Reardon DA, Kaley TJ, Dietrich J, Lim M, Dunn GP, Gan HK et al. Phase 2 study to evaluate the clinical efficacy and safety of MEDI4736 (durvalumab) in patients with glioblastoma (GBM). ASCO Meeting Abstracts. 2016;34(15_suppl):TPS2080.
-
(2016)
ASCO Meeting Abstracts
-
-
-
48
-
-
85015722915
-
A randomized, phase 3, open-label study of nivolumab versus temozolomide (TMZ) in combination with radiotherapy (RT) in adult patients (pts) with newly diagnosed, O-6-methylguanine DNA methyltransferase (MGMT)-unmethylated glioblastoma (GBM)
-
Sampson JH, Omuro AMP, Preusser M, Lim M, Butowski NA, Cloughesy TF et al. ;34(15_suppl):TPS2079
-
Sampson JH, Omuro AMP, Preusser M, Lim M, Butowski NA, Cloughesy TF et al. A randomized, phase 3, open-label study of nivolumab versus temozolomide (TMZ) in combination with radiotherapy (RT) in adult patients (pts) with newly diagnosed, O-6-methylguanine DNA methyltransferase (MGMT)-unmethylated glioblastoma (GBM): CheckMate-498. ASCO Meeting Abstracts. 2016;34(15_suppl):TPS2079.
-
(2016)
CheckMate-498. ASCO Meeting Abstracts
-
-
-
49
-
-
84959378533
-
Immunotherapy for cancer in the central nervous system: current and future directions
-
Binder DC, Davis AA, Wainwright DA. Immunotherapy for cancer in the central nervous system: current and future directions. Oncoimmunol. 2016;5(2), e1082027. doi:10.1080/2162402x.2015.1082027.
-
(2016)
Oncoimmunol
, vol.5
, Issue.2
-
-
Binder, D.C.1
Davis, A.A.2
Wainwright, D.A.3
-
50
-
-
85015767060
-
Safety and antitumor activity of hypofractionated stereotactic irradiation (HFSRT) with pembrolizumab (Pembro) and bevacizumab (Bev) in patients (pts) with recurrent high grade gliomas: Preliminary results from phase I study
-
Sahebjam S, Johnstone PA, Forsyth PAJ, Arrington J, Vrionis FD, Etame AB et al. Safety and antitumor activity of hypofractionated stereotactic irradiation (HFSRT) with pembrolizumab (Pembro) and bevacizumab (Bev) in patients (pts) with recurrent high grade gliomas: Preliminary results from phase I study. ASCO Meeting Abstracts. 2016;34(15_suppl):2041.
-
(2016)
ASCO Meeting Abstracts
, vol.34
, pp. 2016
-
-
Sahebjam, S.1
Johnstone, P.A.2
Forsyth, P.A.J.3
Arrington, J.4
Vrionis, F.D.5
Etame, A.B.6
-
51
-
-
85014833648
-
IT-11A PHASE I/II clinical trial of CT-011 (PIDILIZUMAB) in diffuse intrinsic pontine glioma and relapsed high grade glioma: a preliminary report
-
Fried I, Weintraub M, Ben Ami T, Shen R, Benifla M, Mordechai A, et al. IT-11A PHASE I/II clinical trial of CT-011 (PIDILIZUMAB) in diffuse intrinsic pontine glioma and relapsed high grade glioma: a preliminary report. Neuro-Oncology. 2014;16 suppl 5:v111–2. doi:10.1093/neuonc/nou258.9.
-
(2014)
Neuro-Oncology
, vol.16
, pp. v111-v112
-
-
Fried, I.1
Weintraub, M.2
Ben Ami, T.3
Shen, R.4
Benifla, M.5
Mordechai, A.6
-
52
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
COI: 1:CAS:528:DC%2BC38XhtV2rs7fN, PID: 22658127
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443–54. doi:10.1056/NEJMoa1200690.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
53
-
-
84971280558
-
Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy
-
PID: 27234522
-
Ma W, Gilligan BM, Yuan J, Li T. Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy. J Hematol Oncol. 2016;9(1):47. doi:10.1186/s13045-016-0277-y.
-
(2016)
J Hematol Oncol
, vol.9
, Issue.1
, pp. 47
-
-
Ma, W.1
Gilligan, B.M.2
Yuan, J.3
Li, T.4
-
54
-
-
85032053802
-
Correlation of plasma PD-L1 detectability with age in glioma patients
-
Berghoff AS, Pajenda S, Ilhan-Mutlu A, Widhalm G, Dieckmann K, Hainfellner JA et al. Correlation of plasma PD-L1 detectability with age in glioma patients. ASCO Meeting Abstracts. 2015;33(15_suppl):e13039.
-
(2015)
ASCO Meeting Abstracts
, vol.33
, pp. e13039
-
-
Berghoff, A.S.1
Pajenda, S.2
Ilhan-Mutlu, A.3
Widhalm, G.4
Dieckmann, K.5
Hainfellner, J.A.6
-
55
-
-
68949085209
-
Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors
-
COI: 1:CAS:528:DC%2BD1MXhtV2qurzI, PID: 19028999
-
Jacobs JF, Idema AJ, Bol KF, Nierkens S, Grauer OM, Wesseling P, et al. Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors. Neuro-Oncology. 2009;11(4):394–402. doi:10.1215/15228517-2008-104.
-
(2009)
Neuro-Oncology
, vol.11
, Issue.4
, pp. 394-402
-
-
Jacobs, J.F.1
Idema, A.J.2
Bol, K.F.3
Nierkens, S.4
Grauer, O.M.5
Wesseling, P.6
-
56
-
-
82155168544
-
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
-
COI: 1:CAS:528:DC%2BC38Xms1Cquw%3D%3D, PID: 22123319
-
Hamid O, Schmidt H, Nissan A, Ridolfi L, Aamdal S, Hansson J, et al. A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma. J Transl Med. 2011;9:204. doi:10.1186/1479-5876-9-204.
-
(2011)
J Transl Med
, vol.9
, pp. 204
-
-
Hamid, O.1
Schmidt, H.2
Nissan, A.3
Ridolfi, L.4
Aamdal, S.5
Hansson, J.6
-
57
-
-
58249134743
-
Clinical significance of tumor-infiltrating lymphocytes in lung neoplasms
-
PID: 19161739, discussion 71–2
-
Ruffini E, Asioli S, Filosso PL, Lyberis P, Bruna MC, Macri L, et al. Clinical significance of tumor-infiltrating lymphocytes in lung neoplasms. Ann Thorac Surg. 2009;87(2):365–71. doi:10.1016/j.athoracsur.2008.10.067. discussion 71–2.
-
(2009)
Ann Thorac Surg
, vol.87
, Issue.2
, pp. 365-371
-
-
Ruffini, E.1
Asioli, S.2
Filosso, P.L.3
Lyberis, P.4
Bruna, M.C.5
Macri, L.6
-
58
-
-
84964310813
-
Biomarkers in cancer immunotherapy
-
COI: 1:STN:280:DC%2BC2MvmtlWqtw%3D%3D, PID: 25584891
-
Schumacher Ton N, Kesmir C, van Buuren Marit M. Biomarkers in cancer immunotherapy. Cancer Cell. 2015;27(1):12–4.
-
(2015)
Cancer Cell
, vol.27
, Issue.1
, pp. 12-14
-
-
Schumacher Ton, N.1
Kesmir, C.2
van Buuren Marit, M.3
-
59
-
-
84899061145
-
Exomics and immunogenics: bridging mutational load and immune checkpoints efficacy
-
Champiat S, Ferté C, Lebel-Binay S, Eggermont A, Soria JC. Exomics and immunogenics: bridging mutational load and immune checkpoints efficacy. Oncoimmunol. 2014;3(1), e27817.
-
(2014)
Oncoimmunol
, vol.3
, Issue.1
-
-
Champiat, S.1
Ferté, C.2
Lebel-Binay, S.3
Eggermont, A.4
Soria, J.C.5
-
60
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
PID: 25409260
-
Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med. 2014;371(23):2189–99. doi:10.1056/NEJMoa1406498.
-
(2014)
N Engl J Med
, vol.371
, Issue.23
, pp. 2189-2199
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
Yuan, J.4
Zaretsky, J.M.5
Desrichard, A.6
-
61
-
-
84899836282
-
Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival
-
COI: 1:CAS:528:DC%2BC2cXotVeqtbw%3D, PID: 24782321
-
Brown SD, Warren RL, Gibb EA, Martin SD, Spinelli JJ, Nelson BH, et al. Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival. Genome Res. 2014;24(5):743–50.
-
(2014)
Genome Res
, vol.24
, Issue.5
, pp. 743-750
-
-
Brown, S.D.1
Warren, R.L.2
Gibb, E.A.3
Martin, S.D.4
Spinelli, J.J.5
Nelson, B.H.6
-
62
-
-
84942285381
-
Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1
-
PID: 26181000
-
Howitt BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S, et al. Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1. JAMA oncol. 2015;1(9):1319–23.
-
(2015)
JAMA oncol
, vol.1
, Issue.9
, pp. 1319-1323
-
-
Howitt, B.E.1
Shukla, S.A.2
Sholl, L.M.3
Ritterhouse, L.L.4
Watkins, J.C.5
Rodig, S.6
-
63
-
-
84942922149
-
Correlation between density of CD8+ T-cell infiltrate in microsatellite unstable colorectal cancers and frameshift mutations: a rationale for personalized immunotherapy
-
COI: 1:CAS:528:DC%2BC2MXhsVWqtLnN, PID: 26060019
-
Maby P, Tougeron D, Hamieh M, Mlecnik B, Kora H, Bindea G, et al. Correlation between density of CD8+ T-cell infiltrate in microsatellite unstable colorectal cancers and frameshift mutations: a rationale for personalized immunotherapy. Cancer Res. 2015;75(17):3446–55.
-
(2015)
Cancer Res
, vol.75
, Issue.17
, pp. 3446-3455
-
-
Maby, P.1
Tougeron, D.2
Hamieh, M.3
Mlecnik, B.4
Kora, H.5
Bindea, G.6
-
64
-
-
85017789541
-
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy
-
Tiffany R. Hodges, Martina Ott, Joanne Xiu, Zoran Gatalica, Jeff Swensen, Shouhao Zhou, Jason T. Huse, et al. [in press]
-
Tiffany R. Hodges, Martina Ott, Joanne Xiu, Zoran Gatalica, Jeff Swensen, Shouhao Zhou, Jason T. Huse, et al. Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy. Neurooncology 2017 [in press]
-
(2017)
Neurooncology
-
-
-
65
-
-
77954899030
-
Phase I study of single-agent anti–programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates
-
COI: 1:CAS:528:DC%2BC3cXpslajtLw%3D, PID: 20516446
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, et al. Phase I study of single-agent anti–programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28(19):3167–75. doi:10.1200/jco.2009.26.7609.
-
(2010)
J Clin Oncol
, vol.28
, Issue.19
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
66
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, et al. ;372(26):2509–20. This trial importantly shows a correlation between benefit to anti-PD1 antibody (pembrolizumab) and mismatch-repair status
-
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372(26):2509–20. doi:10.1056/NEJMoa1500596. This trial importantly shows a correlation between benefit to anti-PD1 antibody (pembrolizumab) and mismatch-repair status.
-
(2015)
N Engl J Med
-
-
-
67
-
-
84985868647
-
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) genetic/familial high-risk assessment: colorectal
-
Network NCC. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) genetic/familial high-risk assessment: colorectal, Version 2.2015. 2016.
-
(2016)
Version
, vol.2
, pp. 2015
-
-
Network, N.C.C.1
-
68
-
-
0000240768
-
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas
-
COI: 1:CAS:528:DyaK1cXmvFGmtrs%3D, PID: 9777949
-
Leung SY, Chan TL, Chung LP, Chan ASY, Fan YW, Hung KN, et al. Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. Am J Pathol. 1998;153(4):1181–8. doi:10.1016/S0002-9440(10)65662-3.
-
(1998)
Am J Pathol
, vol.153
, Issue.4
, pp. 1181-1188
-
-
Leung, S.Y.1
Chan, T.L.2
Chung, L.P.3
Chan, A.S.Y.4
Fan, Y.W.5
Hung, K.N.6
-
69
-
-
84995511734
-
Immunogenomics of hypermutated glioblastoma: a patient with germline POLE deficiency treated with checkpoint blockade immunotherapy
-
PID: 27683556
-
Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, et al. Immunogenomics of hypermutated glioblastoma: a patient with germline POLE deficiency treated with checkpoint blockade immunotherapy. Cancer Discov. 2016;6(11):1230–6. doi:10.1158/2159-8290.cd-16-0575.
-
(2016)
Cancer Discov
, vol.6
, Issue.11
, pp. 1230-1236
-
-
Johanns, T.M.1
Miller, C.A.2
Dorward, I.G.3
Tsien, C.4
Chang, E.5
Perry, A.6
-
70
-
-
84991735355
-
Mismatch repair deficiency and response to immune checkpoint blockade
-
Lee V, Murphy A, Le DT, Diaz Jr LA. Mismatch repair deficiency and response to immune checkpoint blockade. Oncologist. 2016. doi:10.1634/theoncologist.2016-0046.
-
(2016)
Oncologist
-
-
Lee, V.1
Murphy, A.2
Le, D.T.3
Diaz, L.A.4
-
71
-
-
34247499001
-
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment
-
COI: 1:CAS:528:DC%2BD2sXjs12rtrs%3D, PID: 17404084
-
Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, et al. Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clin Cancer Res. 2007;13(7):2038–45. doi:10.1158/1078-0432.ccr-06-2149.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.7
, pp. 2038-2045
-
-
Cahill, D.P.1
Levine, K.K.2
Betensky, R.A.3
Codd, P.J.4
Romany, C.A.5
Reavie, L.B.6
-
72
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455(7216):1061–8. doi:10.1038/nature07385.
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
73
-
-
68049095262
-
MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance
-
COI: 1:CAS:528:DC%2BD1MXosV2ltL8%3D, PID: 19584161
-
Yip S, Miao J, Cahill DP, Iafrate AJ, Aldape K, Nutt CL, et al. MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance. Clin Cancer Res. 2009;15(14):4622–9. doi:10.1158/1078-0432.ccr-08-3012.
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.14
, pp. 4622-4629
-
-
Yip, S.1
Miao, J.2
Cahill, D.P.3
Iafrate, A.J.4
Aldape, K.5
Nutt, C.L.6
-
74
-
-
85047103552
-
Association of MSH6 mutation with glioma susceptibility, drug resistance and progression
-
PID: 27446556
-
Xie C, Sheng H, Zhang N, Li S, Wei X, Zheng X. Association of MSH6 mutation with glioma susceptibility, drug resistance and progression. Mol Clin Oncol. 2016;5(2):236–40. doi:10.3892/mco.2016.907.
-
(2016)
Mol Clin Oncol
, vol.5
, Issue.2
, pp. 236-240
-
-
Xie, C.1
Sheng, H.2
Zhang, N.3
Li, S.4
Wei, X.5
Zheng, X.6
-
75
-
-
84892373020
-
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
-
COI: 1:CAS:528:DC%2BC2cXktVyktQ%3D%3D
-
Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science (New York, NY). 2014;343(6167):189–93. doi:10.1126/science.1239947.
-
(2014)
Science (New York, NY)
, vol.343
, Issue.6167
, pp. 189-193
-
-
Johnson, B.E.1
Mazor, T.2
Hong, C.3
Barnes, M.4
Aihara, K.5
McLean, C.Y.6
-
76
-
-
84939992139
-
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment
-
PID: 25724300
-
van Thuijl HF, Mazor T, Johnson BE, Fouse SD, Aihara K, Hong C, et al. Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment. Acta Neuropathol. 2015;129(4):597–607. doi:10.1007/s00401-015-1403-6.
-
(2015)
Acta Neuropathol
, vol.129
, Issue.4
, pp. 597-607
-
-
van Thuijl, H.F.1
Mazor, T.2
Johnson, B.E.3
Fouse, S.D.4
Aihara, K.5
Hong, C.6
-
77
-
-
84884488060
-
Integrated analysis of mismatch repair system in malignant astrocytomas
-
COI: 1:CAS:528:DC%2BC3sXhsFeiurvP, PID: 24073290
-
Rodriguez-Hernandez I, Garcia JL, Santos-Briz A, Hernandez-Lain A, Gonzalez-Valero JM, Gomez-Moreta JA, et al. Integrated analysis of mismatch repair system in malignant astrocytomas. PLoS One. 2013;8(9), e76401. doi:10.1371/journal.pone.0076401.
-
(2013)
PLoS One
, vol.8
, Issue.9
-
-
Rodriguez-Hernandez, I.1
Garcia, J.L.2
Santos-Briz, A.3
Hernandez-Lain, A.4
Gonzalez-Valero, J.M.5
Gomez-Moreta, J.A.6
-
78
-
-
84977071049
-
Biomarkers associated with checkpoint inhibitors
-
COI: 1:STN:280:DC%2BC28bktVeisw%3D%3D
-
Manson G, Norwood J, Marabelle A, Kohrt H, Houot R. Biomarkers associated with checkpoint inhibitors. Ann Oncol Off J Eur Soc Med Oncol/ESMO. 2016;27(7):1199–206. doi:10.1093/annonc/mdw181.
-
(2016)
Ann. Oncol Off J Eur Soc Med Oncol/ESMO
, vol.27
, Issue.7
, pp. 1199-1206
-
-
Manson, G.1
Norwood, J.2
Marabelle, A.3
Kohrt, H.4
Houot, R.5
-
79
-
-
84937516687
-
Biomarkers for glioma immunotherapy: the next generation
-
COI: 1:CAS:528:DC%2BC2MXjvFWlurk%3D
-
Sims JS, Ung TH, Neira JA, Canoll P, Bruce JN. Biomarkers for glioma immunotherapy: the next generation. J Neuro-Oncol. 2015;123(3):359–72. doi:10.1007/s11060-015-1746-9.
-
(2015)
J Neuro-Oncol
, vol.123
, Issue.3
, pp. 359-372
-
-
Sims, J.S.1
Ung, T.H.2
Neira, J.A.3
Canoll, P.4
Bruce, J.N.5
-
80
-
-
84904391384
-
Immunotherapy for brain cancer: recent progress and future promise
-
PID: 24771646
-
Jackson CM, Lim M, Drake CG. Immunotherapy for brain cancer: recent progress and future promise. Clin Cancer Res. 2014;20(14):3651–9. doi:10.1158/1078-0432.ccr-13-2057.
-
(2014)
Clin. Cancer Res
, vol.20
, Issue.14
, pp. 3651-3659
-
-
Jackson, C.M.1
Lim, M.2
Drake, C.G.3
-
81
-
-
84977110484
-
Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies
-
COI: 1:STN:280:DC%2BC28jktVKnsQ%3D%3D
-
Sanmamed MF, Chester C, Melero I, Kohrt H. Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies. Ann Oncol Off J Eur Soc Med Oncol/ESMO. 2016;27(7):1190–8. doi:10.1093/annonc/mdw041.
-
(2016)
Ann. Oncol Off J Eur Soc Med Oncol/ESMO
, vol.27
, Issue.7
, pp. 1190-1198
-
-
Sanmamed, M.F.1
Chester, C.2
Melero, I.3
Kohrt, H.4
-
82
-
-
84961673897
-
Challenges of phase 1 clinical trials evaluating immune checkpoint-targeted antibodies
-
COI: 1:STN:280:DC%2BC28vislGhsQ%3D%3D
-
Postel-Vinay S, Aspeslagh S, Lanoy E, Robert C, Soria JC, Marabelle A. Challenges of phase 1 clinical trials evaluating immune checkpoint-targeted antibodies. Ann Oncol Off J Eur Soc Med Oncol/ESMO. 2016;27(2):214–24. doi:10.1093/annonc/mdv550.
-
(2016)
Ann. Oncol Off J Eur Soc Med Oncol/ESMO
, vol.27
, Issue.2
, pp. 214-224
-
-
Postel-Vinay, S.1
Aspeslagh, S.2
Lanoy, E.3
Robert, C.4
Soria, J.C.5
Marabelle, A.6
-
83
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
COI: 1:CAS:528:DC%2BC2cXpsVSku74%3D
-
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol Off J Am Soc Clin Oncol. 2014;32(10):1020–30. doi:10.1200/jco.2013.53.0105.
-
(2014)
J Clin Oncol Off. J Am Soc Clin Oncol
, vol.32
, Issue.10
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
84
-
-
84875039618
-
Combining radiotherapy and cancer immunotherapy: a paradigm shift
-
COI: 1:CAS:528:DC%2BC3sXjtFShs7g%3D, PID: 23291374
-
Formenti SC, Demaria S. Combining radiotherapy and cancer immunotherapy: a paradigm shift. J Natl Cancer Inst. 2013;105(4):256–65. doi:10.1093/jnci/djs629.
-
(2013)
J Natl Cancer Inst
, vol.105
, Issue.4
, pp. 256-265
-
-
Formenti, S.C.1
Demaria, S.2
-
85
-
-
84960956996
-
Immunotherapy response assessment in neuro-oncology: a report of the RANO working group
-
PID: 26545842
-
Okada H, Weller M, Huang R, Finocchiaro G, Gilbert MR, Wick W, et al. Immunotherapy response assessment in neuro-oncology: a report of the RANO working group. Lancet Oncol. 2015;16(15):e534–42. doi:10.1016/s1470-2045(15)00088-1.
-
(2015)
Lancet Oncol
, vol.16
, Issue.15
, pp. e534-e542
-
-
Okada, H.1
Weller, M.2
Huang, R.3
Finocchiaro, G.4
Gilbert, M.R.5
Wick, W.6
-
86
-
-
79951641692
-
Immunotherapy coming of age: what will it take to make it standard of care for glioblastoma?
-
PID: 21149252
-
Heimberger AB, Sampson JH. Immunotherapy coming of age: what will it take to make it standard of care for glioblastoma? Neuro-Oncology. 2011;13(1):3–13. doi:10.1093/neuonc/noq169.
-
(2011)
Neuro-Oncology
, vol.13
, Issue.1
, pp. 3-13
-
-
Heimberger, A.B.1
Sampson, J.H.2
-
87
-
-
84949988089
-
Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies
-
COI: 1:STN:280:DC%2BC283it1Khtw%3D%3D
-
Naidoo J, Page DB, Li BT, Connell LC, Schindler K, Lacouture ME, et al. Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies. Ann Oncol Off J Eur Soc Med Oncol/ESMO. 2015;26(12):2375–91. doi:10.1093/annonc/mdv383.
-
(2015)
Ann. Oncol Off J Eur Soc Med Oncol/ESMO
, vol.26
, Issue.12
, pp. 2375-2391
-
-
Naidoo, J.1
Page, D.B.2
Li, B.T.3
Connell, L.C.4
Schindler, K.5
Lacouture, M.E.6
-
88
-
-
84941619877
-
A systematic review of immune-related adverse event reporting in clinical trials of immune checkpoint inhibitors
-
COI: 1:STN:280:DC%2BC2MjltlamtQ%3D%3D
-
Chen TW, Razak AR, Bedard PL, Siu LL, Hansen AR. A systematic review of immune-related adverse event reporting in clinical trials of immune checkpoint inhibitors. Ann Oncol Off J Eur Soc Med Oncol/ESMO. 2015;26(9):1824–9. doi:10.1093/annonc/mdv182.
-
(2015)
Ann. Oncol Off J Eur Soc Med Oncol/ESMO
, vol.26
, Issue.9
, pp. 1824-1829
-
-
Chen, T.W.1
Razak, A.R.2
Bedard, P.L.3
Siu, L.L.4
Hansen, A.R.5
|