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Volumn 8, Issue 9, 2013, Pages

Integrated Analysis of Mismatch Repair System in Malignant Astrocytomas

Author keywords

[No Author keywords available]

Indexed keywords

MISMATCH REPAIR PROTEIN; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

EID: 84884488060     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076401     Document Type: Article
Times cited : (23)

References (52)
  • 1
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • Ohgaki H, Kleihues P, (2005) Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64: 479-489. PubMed: 15977639.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 2
    • 84862010453 scopus 로고    scopus 로고
    • Malignant glioma grade 3 and 4: How relevant is timing of radiotherapy?
    • doi:10.1016/j.clineuro.2011.12.024
    • Wehming FM, Wiese B, Nakamura M, Bremer M, Karstens JH, et al. (2012) Malignant glioma grade 3 and 4: How relevant is timing of radiotherapy? Clin Neurol Neurosurg 114: 617-621. doi:10.1016/j.clineuro.2011.12.024. PubMed: 22244251.
    • (2012) Clin Neurol Neurosurg , vol.114 , pp. 617-621
    • Wehming, F.M.1    Wiese, B.2    Nakamura, M.3    Bremer, M.4    Karstens, J.H.5
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • doi:10.1016/S1470-2045(09)70025-7
    • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-466. doi:10.1016/S1470-2045(09)70025-7. PubMed: 19269895.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    van den Bent, M.J.4    Taphoorn, M.J.5
  • 4
    • 58149471244 scopus 로고    scopus 로고
    • Epidemiology of brain tumors
    • doi:10.1007/978-1-60327-492-0_14
    • Ohgaki H, (2009) Epidemiology of brain tumors. Methods Mol Biol 472: 323-342. doi:10.1007/978-1-60327-492-0_14. PubMed: 19107440.
    • (2009) Methods Mol Biol , vol.472 , pp. 323-342
    • Ohgaki, H.1
  • 5
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • doi:10.1056/NEJMra0708126
    • Wen PY, Kesari S, (2008) Malignant gliomas in adults. N Engl J Med 359: 492-507. doi:10.1056/NEJMra0708126. PubMed: 18669428.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 6
    • 27744606737 scopus 로고    scopus 로고
    • Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
    • doi:10.1056/NEJMoa051918
    • Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, et al. (2005) Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 353: 2012-2024. doi:10.1056/NEJMoa051918. PubMed: 16282176.
    • (2005) N Engl J Med , vol.353 , pp. 2012-2024
    • Mellinghoff, I.K.1    Wang, M.Y.2    Vivanco, I.3    Haas-Kogan, D.A.4    Zhu, S.5
  • 7
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • doi:10.1056/NEJMoa0808710
    • Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, et al. (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360: 765-773. doi:10.1056/NEJMoa0808710. PubMed: 19228619.
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3    McLendon, R.4    Rasheed, B.A.5
  • 8
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • The Cancer Genome Atlas (TCGA) Research Network
    • The Cancer Genome Atlas (TCGA) Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 9
    • 75149166496 scopus 로고    scopus 로고
    • MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
    • doi:10.1038/nrneurol.2009.197
    • Weller M, Stupp R, Reifenberger G, Brandes AA, van den Bent MJ, et al. (2010) MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat. Rev Neurol 6: 39-51. doi:10.1038/nrneurol.2009.197.
    • (2010) Nat Rev Neurol , vol.6 , pp. 39-51
    • Weller, M.1    Stupp, R.2    Reifenberger, G.3    Brandes, A.A.4    van den Bent, M.J.5
  • 10
    • 77951599543 scopus 로고    scopus 로고
    • Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma
    • doi:10.1038/nrc2818
    • Huse JT, Holland EC, (2010) Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10: 319-331. doi:10.1038/nrc2818. PubMed: 20414201.
    • (2010) Nat Rev Cancer , vol.10 , pp. 319-331
    • Huse, J.T.1    Holland, E.C.2
  • 11
    • 10744233937 scopus 로고    scopus 로고
    • Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
    • doi:10.1093/jnci/djh034
    • Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, et al. (2004) 2004) Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 96: 261-268. doi:10.1093/jnci/djh034. PubMed: 14970275.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 261-268
    • Umar, A.1    Boland, C.R.2    Terdiman, J.P.3    Syngal, S.4    de la Chapelle, A.5
  • 12
    • 44949202465 scopus 로고    scopus 로고
    • The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome
    • doi:10.1002/ijc.23508
    • Watson P, Vasen HF, Mecklin JP, Bernstein I, Aarnio M, et al. (2008) The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer 123: 444-449. doi:10.1002/ijc.23508. PubMed: 18398828.
    • (2008) Int J Cancer , vol.123 , pp. 444-449
    • Watson, P.1    Vasen, H.F.2    Mecklin, J.P.3    Bernstein, I.4    Aarnio, M.5
  • 13
    • 63149194159 scopus 로고    scopus 로고
    • Management of extracolonic tumours in patients with Lynch syndrome
    • doi:10.1016/S1470-2045(09)70041-5
    • Koornstra JJ, Mourits MJ, Sijmons RH, Leliveld AM, Hollema H, et al. (2009) Management of extracolonic tumours in patients with Lynch syndrome. Lancet Oncol 10: 400-408. doi:10.1016/S1470-2045(09)70041-5. PubMed: 19341971.
    • (2009) Lancet Oncol , vol.10 , pp. 400-408
    • Koornstra, J.J.1    Mourits, M.J.2    Sijmons, R.H.3    Leliveld, A.M.4    Hollema, H.5
  • 14
    • 67650924286 scopus 로고    scopus 로고
    • Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
    • doi:10.1111/j.1399-0004.2009.01230.x
    • Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, et al. (2009) Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet 76: 1-18. doi:10.1111/j.1399-0004.2009.01230.x. PubMed: 19659756.
    • (2009) Clin Genet , vol.76 , pp. 1-18
    • Lynch, H.T.1    Lynch, P.M.2    Lanspa, S.J.3    Snyder, C.L.4    Lynch, J.F.5
  • 15
    • 24144463165 scopus 로고    scopus 로고
    • Lynch syndrome genes
    • doi:10.1007/s10689-004-7993-0
    • Peltomäki P, (2005) Lynch syndrome genes. Fam Cancer 4: 227-232. doi:10.1007/s10689-004-7993-0. PubMed: 16136382.
    • (2005) Fam Cancer , vol.4 , pp. 227-232
    • Peltomäki, P.1
  • 16
    • 84863903548 scopus 로고    scopus 로고
    • Screening Patients With Colorectal Cancer for Lynch Syndrome: What Are We Waiting For?
    • doi:10.1200/JCO.2011.40.7171
    • Kastrinos F, Syngal S, (2012) Screening Patients With Colorectal Cancer for Lynch Syndrome: What Are We Waiting For? J Clin Oncol 30: 1024-1027. doi:10.1200/JCO.2011.40.7171. PubMed: 22355054.
    • (2012) J Clin Oncol , vol.30 , pp. 1024-1027
    • Kastrinos, F.1    Syngal, S.2
  • 17
    • 53449086387 scopus 로고    scopus 로고
    • MLH1 -93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer
    • doi:10.1002/ijc.23770
    • Allan JM, Shorto J, Adlard J, Bury J, Coggins R, et al. (2008) MLH1-93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer. Int J Cancer 123: 2456-2459. doi:10.1002/ijc.23770. PubMed: 18712731.
    • (2008) Int J Cancer , vol.123 , pp. 2456-2459
    • Allan, J.M.1    Shorto, J.2    Adlard, J.3    Bury, J.4    Coggins, R.5
  • 18
    • 78149463044 scopus 로고    scopus 로고
    • Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer
    • doi:10.1371/journal.pone.0013314
    • Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, et al. (2010) Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer. PLOS ONE 5: e13314. doi:10.1371/journal.pone.0013314. PubMed: 20967208.
    • (2010) PLOS ONE , vol.5
    • Mrkonjic, M.1    Roslin, N.M.2    Greenwood, C.M.3    Raptis, S.4    Pollett, A.5
  • 19
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • doi:10.1007/s00401-007-0243-4
    • Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, et al. (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114: 97-109. doi:10.1007/s00401-007-0243-4. PubMed: 17618441.
    • (2007) Acta Neuropathol , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3    Cavenee, W.K.4    Burger, P.C.5
  • 20
    • 34548760880 scopus 로고    scopus 로고
    • MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas
    • doi:10.1038/labinvest.3700664
    • Jeuken JW, Cornelissen SJ, Vriezen M, Dekkers MM, Errami A, et al. (2007) MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas. Lab Invest 87: 1055-1065. doi:10.1038/labinvest.3700664. PubMed: 17700563.
    • (2007) Lab Invest , vol.87 , pp. 1055-1065
    • Jeuken, J.W.1    Cornelissen, S.J.2    Vriezen, M.3    Dekkers, M.M.4    Errami, A.5
  • 21
    • 36749092263 scopus 로고    scopus 로고
    • Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis
    • doi:10.1038/sj.onc.1210581
    • Capel E, Fléjou JF, Hamelin R, (2007) Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis. Oncogene 26: 7596-7600. doi:10.1038/sj.onc.1210581. PubMed: 17546041.
    • (2007) Oncogene , vol.26 , pp. 7596-7600
    • Capel, E.1    Fléjou, J.F.2    Hamelin, R.3
  • 22
    • 79954535847 scopus 로고    scopus 로고
    • Targeted SNP genotyping using the TaqMan(R) assay
    • doi:10.1007/978-1-61737-954-3_6
    • Schleinitz D, Distefano JK, Kovacs P, (2011) Targeted SNP genotyping using the TaqMan(R) assay. Methods Mol Biol 700: 77-87. doi:10.1007/978-1-61737-954-3_6. PubMed: 21204028.
    • (2011) Methods Mol Biol , vol.700 , pp. 77-87
    • Schleinitz, D.1    Distefano, J.K.2    Kovacs, P.3
  • 23
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, et al. (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257. PubMed: 9823339.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5
  • 24
    • 0027433113 scopus 로고
    • Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes
    • doi:10.1073/pnas.90.21.10325
    • Ganguly A, Rock MJ, Prockop DJ, (1993) Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes. Proc Natl Acad Sci U S A 90: 10325-10329. doi:10.1073/pnas.90.21.10325. PubMed: 8234293.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10325-10329
    • Ganguly, A.1    Rock, M.J.2    Prockop, D.J.3
  • 25
    • 40549109545 scopus 로고    scopus 로고
    • Classification of ambiguous mutations in DNA mismatch repair genes identified in a population-based study of colorectal cancer
    • doi:10.1002/humu.20635
    • Barnetson RA, Cartwright N, van Vliet A, Haq N, Drew K, et al. (2008) Classification of ambiguous mutations in DNA mismatch repair genes identified in a population-based study of colorectal cancer. Hum Mutat 29: 367-374. doi:10.1002/humu.20635. PubMed: 18033691.
    • (2008) Hum Mutat , vol.29 , pp. 367-374
    • Barnetson, R.A.1    Cartwright, N.2    van Vliet, A.3    Haq, N.4    Drew, K.5
  • 26
    • 33745281285 scopus 로고    scopus 로고
    • Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features
    • doi:10.1038/sj.ejhg.5201628
    • Belvederesi L, Bianchi F, Loretelli C, Gagliardini D, Galizia E, et al. (2006) Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features. Eur J Hum Genet 14: 853-859. doi:10.1038/sj.ejhg.5201628. PubMed: 16724012.
    • (2006) Eur J Hum Genet , vol.14 , pp. 853-859
    • Belvederesi, L.1    Bianchi, F.2    Loretelli, C.3    Gagliardini, D.4    Galizia, E.5
  • 27
    • 0037051664 scopus 로고    scopus 로고
    • Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain
    • doi:10.1002/ijc.10240
    • Caldes T, Godino J, de la Hoya M, Garcia Carbonero I, Perez Segura P, et al. (2002) Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain. Int J Cancer 98: 774-779. doi:10.1002/ijc.10240. PubMed: 11920650.
    • (2002) Int J Cancer , vol.98 , pp. 774-779
    • Caldes, T.1    Godino, J.2    de la Hoya, M.3    Garcia Carbonero, I.4    Perez Segura, P.5
  • 28
    • 84861454516 scopus 로고    scopus 로고
    • Primary brain tumours in adults
    • doi:10.1016/S0140-6736(11)61346-9
    • Ricard D, Idbaih A, Ducray F, Lahutte M, Hoang-Xuan K, et al. (2012) Primary brain tumours in adults. Lancet 379: 1984-1996. doi:10.1016/S0140-6736(11)61346-9. PubMed: 22510398.
    • (2012) Lancet , vol.379 , pp. 1984-1996
    • Ricard, D.1    Idbaih, A.2    Ducray, F.3    Lahutte, M.4    Hoang-Xuan, K.5
  • 29
    • 33745902791 scopus 로고    scopus 로고
    • Alterations of p53, BCL-2, and hMSH2 protein expression in the normal brain tissues, gliosis, and gliomas
    • doi:10.1111/j.1365-2613.2006.00482.x
    • Hussein MR, El-Ghorori RM, El-Rahman YG, (2006) Alterations of p53, BCL-2, and hMSH2 protein expression in the normal brain tissues, gliosis, and gliomas. Int J Exp Pathol 87: 297-306. doi:10.1111/j.1365-2613.2006.00482.x. PubMed: 16875495.
    • (2006) Int J Exp Pathol , vol.87 , pp. 297-306
    • Hussein, M.R.1    El-Ghorori, R.M.2    El-Rahman, Y.G.3
  • 30
    • 1342287204 scopus 로고    scopus 로고
    • Increased hMSH2 protein expression in glioblastoma multiforme
    • doi:10.1023/B:NEON.0000013482.99032.b0
    • Srivastava T, Chattopadhyay P, Mahapatra AK, Sarkar C, Sinha S, (2004) Increased hMSH2 protein expression in glioblastoma multiforme. J Neuro Oncol 66: 51-57. doi:10.1023/B:NEON.0000013482.99032.b0. PubMed: 15015769.
    • (2004) J Neuro Oncol , vol.66 , pp. 51-57
    • Srivastava, T.1    Chattopadhyay, P.2    Mahapatra, A.K.3    Sarkar, C.4    Sinha, S.5
  • 31
    • 0035983779 scopus 로고    scopus 로고
    • Expression of hMSH2 and hMLH1 proteins of the human DNA mismatch repair system in salivary gland tumors
    • doi:10.1034/j.1600-0714.2002.310407.x
    • Castrilli G, Fabiano A, La Torre G, Marigo L, Piantelli C, et al. (2002) Expression of hMSH2 and hMLH1 proteins of the human DNA mismatch repair system in salivary gland tumors. J Oral Pathol Med 31: 234-238. doi:10.1034/j.1600-0714.2002.310407.x. PubMed: 12076327.
    • (2002) J Oral Pathol Med , vol.31 , pp. 234-238
    • Castrilli, G.1    Fabiano, A.2    La Torre, G.3    Marigo, L.4    Piantelli, C.5
  • 32
    • 0035570139 scopus 로고    scopus 로고
    • DNA mismatch repair enzyme hMSH2 in malignant melanoma: increased immunoreactivity as compared to acquired melanocytic nevi and strong mRNA expression in melanoma cell lines
    • doi:10.1023/A:1014472314354
    • Rass K, Gutwein P, Welter C, Meineke V, Tilgen W, et al. (2001) DNA mismatch repair enzyme hMSH2 in malignant melanoma: increased immunoreactivity as compared to acquired melanocytic nevi and strong mRNA expression in melanoma cell lines. Histochem J 33: 459-467. doi:10.1023/A:1014472314354. PubMed: 11931386.
    • (2001) Histochem J , vol.33 , pp. 459-467
    • Rass, K.1    Gutwein, P.2    Welter, C.3    Meineke, V.4    Tilgen, W.5
  • 33
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: the DNA hypermethylome
    • Esteller M, (2007) Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 16Spec No 1: R50-59. PubMed: 17613547.
    • (2007) Hum Mol Genet , vol.16 , Issue.1
    • Esteller, M.1
  • 34
    • 0037434934 scopus 로고    scopus 로고
    • Multiple sites required for expression in 5'-flanking region of the hMLH1 gene
    • doi:10.1016/S0378-1119(03)00385-8
    • Arita M, Zhong X, Min Z, Hemmi H, Shimatake H, (2003) Multiple sites required for expression in 5'-flanking region of the hMLH1 gene. Gene 306: 57-65. doi:10.1016/S0378-1119(03)00385-8. PubMed: 12657467.
    • (2003) Gene , vol.306 , pp. 57-65
    • Arita, M.1    Zhong, X.2    Min, Z.3    Hemmi, H.4    Shimatake, H.5
  • 35
    • 33947117457 scopus 로고    scopus 로고
    • Evidence for heritable predisposition to epigenetic silencing of MLH1
    • doi:10.1002/ijc.22406
    • Chen H, Taylor NP, Sotamaa KM, Mutch DG, Powell MA, et al. (2007) Evidence for heritable predisposition to epigenetic silencing of MLH1. Int J Cancer 120: 1684-1688. doi:10.1002/ijc.22406. PubMed: 17230510.
    • (2007) Int J Cancer , vol.120 , pp. 1684-1688
    • Chen, H.1    Taylor, N.P.2    Sotamaa, K.M.3    Mutch, D.G.4    Powell, M.A.5
  • 36
    • 20444505189 scopus 로고    scopus 로고
    • Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk
    • doi:10.1158/1078-0432.CCR-04-2534
    • Lee KM, Choi JY, Kang C, Kang CP, Park SK, et al. (2005) Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. Clin Cancer Res 11: 4620-4626. doi:10.1158/1078-0432.CCR-04-2534. PubMed: 15958648.
    • (2005) Clin Cancer Res , vol.11 , pp. 4620-4626
    • Lee, K.M.1    Choi, J.Y.2    Kang, C.3    Kang, C.P.4    Park, S.K.5
  • 37
    • 7044254969 scopus 로고    scopus 로고
    • 93G-- A polymorphism of hMLH1 and risk of primary lung cancer
    • doi:10.1002/ijc.20359
    • Park SH, Lee GY, Jeon HS, Lee SJ, Kim KM, et al. (2004) 93G-- A polymorphism of hMLH1 and risk of primary lung cancer. Int J Cancer 112: 678-682. doi:10.1002/ijc.20359. PubMed: 15382050.
    • (2004) Int J Cancer , vol.112 , pp. 678-682
    • Park, S.H.1    Lee, G.Y.2    Jeon, H.S.3    Lee, S.J.4    Kim, K.M.5
  • 38
    • 33947528232 scopus 로고    scopus 로고
    • Microsatellite instability in pediatric and adult high-grade gliomas
    • doi:10.1111/j.1750-3639.2007.00049.x
    • Eckert A, Kloor M, Giersch A, Ahmadi R, Herold-Mende C, et al. (2007) Microsatellite instability in pediatric and adult high-grade gliomas. Brain Pathol 17: 146-150. doi:10.1111/j.1750-3639.2007.00049.x. PubMed: 17388945.
    • (2007) Brain Pathol , vol.17 , pp. 146-150
    • Eckert, A.1    Kloor, M.2    Giersch, A.3    Ahmadi, R.4    Herold-Mende, C.5
  • 39
    • 79958072588 scopus 로고    scopus 로고
    • Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
    • doi:10.1002/ijc.26083
    • Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, et al. (2011) Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. Int J Cancer 129: 659-670. doi:10.1002/ijc.26083. PubMed: 21425258.
    • (2011) Int J Cancer , vol.129 , pp. 659-670
    • Felsberg, J.1    Thon, N.2    Eigenbrod, S.3    Hentschel, B.4    Sabel, M.C.5
  • 40
    • 79957555791 scopus 로고    scopus 로고
    • Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation
    • doi:10.1371/journal.pone.0020588
    • Viana-Pereira M, Lee A, Popov S, Bax DA, Al-Sarraj S, et al. (2011) Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLOS ONE 6: e20588. doi:10.1371/journal.pone.0020588. PubMed: 21637783.
    • (2011) PLOS ONE , vol.6
    • Viana-Pereira, M.1    Lee, A.2    Popov, S.3    Bax, D.A.4    Al-Sarraj, S.5
  • 41
    • 13244269748 scopus 로고    scopus 로고
    • Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme
    • doi:10.1007/s00432-004-0592-5
    • Martinez R, Schackert HK, Appelt H, Plaschke J, Baretton G, et al. (2005) Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme. J Cancer Res Clin Oncol 131: 87-93. doi:10.1007/s00432-004-0592-5. PubMed: 15672285.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 87-93
    • Martinez, R.1    Schackert, H.K.2    Appelt, H.3    Plaschke, J.4    Baretton, G.5
  • 42
    • 76549111046 scopus 로고    scopus 로고
    • Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes
    • doi:10.1158/1538-7445.AM10-431
    • Shah SN, Hile SE, Eckert KA, (2010) Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes. Cancer Res 70: 431-435. doi:10.1158/1538-7445.AM10-431. PubMed: 20068152.
    • (2010) Cancer Res , vol.70 , pp. 431-435
    • Shah, S.N.1    Hile, S.E.2    Eckert, K.A.3
  • 43
    • 34548244153 scopus 로고    scopus 로고
    • Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression
    • doi:10.1007/s00432-007-0220-2
    • Alldinger I, Schaefer KL, Goedde D, Ottaviano L, Dirksen U, et al. (2007) Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression. J Cancer Res Clin Oncol 133: 749-759. doi:10.1007/s00432-007-0220-2. PubMed: 17530287.
    • (2007) J Cancer Res Clin Oncol , vol.133 , pp. 749-759
    • Alldinger, I.1    Schaefer, K.L.2    Goedde, D.3    Ottaviano, L.4    Dirksen, U.5
  • 44
    • 70349622987 scopus 로고    scopus 로고
    • Analysis of microsatellite instability in medulloblastoma
    • doi:10.1215/15228517-2008-115
    • Viana-Pereira M, Almeida I, Sousa S, Mahler-Araújo B, Seruca R, et al. (2009) Analysis of microsatellite instability in medulloblastoma. Neuro Oncol 11: 458-467. doi:10.1215/15228517-2008-115. PubMed: 19179424.
    • (2009) Neuro Oncol , vol.11 , pp. 458-467
    • Viana-Pereira, M.1    Almeida, I.2    Sousa, S.3    Mahler-Araújo, B.4    Seruca, R.5
  • 45
    • 68049095262 scopus 로고    scopus 로고
    • MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance
    • doi:10.1158/1078-0432.CCR-08-3012
    • Yip S, Miao J, Cahill DP, Iafrate AJ, Aldape K, et al. (2009) MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance. Clin Cancer Res 15: 4622-4629. doi:10.1158/1078-0432.CCR-08-3012. PubMed: 19584161.
    • (2009) Clin Cancer Res , vol.15 , pp. 4622-4629
    • Yip, S.1    Miao, J.2    Cahill, D.P.3    Iafrate, A.J.4    Aldape, K.5
  • 46
    • 34247499001 scopus 로고    scopus 로고
    • Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment
    • doi:10.1158/1078-0432.CCR-06-2149
    • Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, et al. (2007) Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clin Cancer Res 13: 2038-2045. doi:10.1158/1078-0432.CCR-06-2149. PubMed: 17404084.
    • (2007) Clin Cancer Res , vol.13 , pp. 2038-2045
    • Cahill, D.P.1    Levine, K.K.2    Betensky, R.A.3    Codd, P.J.4    Romany, C.A.5
  • 47
    • 51049123410 scopus 로고    scopus 로고
    • Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma
    • doi:10.1158/1078-0432.CCR-07-4807
    • Maxwell JA, Johnson SP, McLendon RE, Lister DW, Horne KS, et al. (2008) Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma. Clin Cancer Res 14: 4859-4868. doi:10.1158/1078-0432.CCR-07-4807. PubMed: 18676759.
    • (2008) Clin Cancer Res , vol.14 , pp. 4859-4868
    • Maxwell, J.A.1    Johnson, S.P.2    McLendon, R.E.3    Lister, D.W.4    Horne, K.S.5
  • 48
    • 77956608245 scopus 로고    scopus 로고
    • The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma
    • doi:10.1179/016164110X12645013515052
    • Stark AM, Doukas A, Hugo HH, Mehdorn HM, (2010) The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma. Neurol Res 32: 816-820. doi:10.1179/016164110X12645013515052. PubMed: 20223108.
    • (2010) Neurol Res , vol.32 , pp. 816-820
    • Stark, A.M.1    Doukas, A.2    Hugo, H.H.3    Mehdorn, H.M.4
  • 49
    • 0036711451 scopus 로고    scopus 로고
    • Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review
    • Laperriere N, Zuraw L, Cairncross G, Cancer Care Ontario Practice Guidelines Initiative Neuro-Oncology Disease Site G, (2002) Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review. Radiother Oncol 64: 259-273.
    • (2002) Radiother Oncol , vol.64 , pp. 259-273
    • Laperriere, N.1    Zuraw, L.2    Cairncross, G.3
  • 50
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • doi:10.1056/NEJMoa043330
    • Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996. doi:10.1056/NEJMoa043330. PubMed: 15758009.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3    Weller, M.4    Fisher, B.5
  • 51
    • 73349112598 scopus 로고    scopus 로고
    • Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy
    • doi:10.1200/JCO.2009.24.5985
    • DeAngelis LM, (2009) Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. J Clin Oncol 27: 5861-5862. doi:10.1200/JCO.2009.24.5985. PubMed: 19901101.
    • (2009) J Clin Oncol , vol.27 , pp. 5861-5862
    • DeAngelis, L.M.1
  • 52
    • 79953707633 scopus 로고    scopus 로고
    • Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair
    • doi:10.1093/nar/gkq1095
    • Shahi A, Lee JH, Kang Y, Lee SH, Hyun JW, et al. (2011) Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair. Nucleic Acids Res 39: 2130-2143. doi:10.1093/nar/gkq1095. PubMed: 21075794.
    • (2011) Nucleic Acids Res , vol.39 , pp. 2130-2143
    • Shahi, A.1    Lee, J.H.2    Kang, Y.3    Lee, S.H.4    Hyun, J.W.5


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