-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
R Stupp WP Mason MJ van den Bent, et al. 2005 Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 987 996 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D 15758009 (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
3
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
This is the update of the original EORTC/NCIC study [2] that defined the standard of care for TMZ/RT with 5-year survival data
-
Stupp R, Hegi ME, Mason WP, et al.: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009, 10:459-466. This is the update of the original EORTC/NCIC study [2] that defined the standard of care for TMZ/RT with 5-year survival data.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
4
-
-
67349097860
-
Long-term use of temozolomide: Could you use temozolomide safely for life in gliomas?
-
10.1016/j.jocn.2008.09.005 1:CAS:528:DC%2BD1MXltl2lu7c%3D 19303779
-
M Khasraw D Bell H Wheeler 2009 Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? J Clin Neurosci 16 854 855 10.1016/j.jocn.2008.09.005 1:CAS:528:DC%2BD1MXltl2lu7c%3D 19303779
-
(2009)
J Clin Neurosci
, vol.16
, pp. 854-855
-
-
Khasraw, M.1
Bell, D.2
Wheeler, H.3
-
5
-
-
34547476243
-
Survey of treatment recommendations for anaplastic oligodendroglioma
-
DOI 10.1215/15228517-2007-002
-
LE Abrey DN Louis N Paleologos, et al. 2007 Survey of treatment recommendations for anaplastic oligodendroglioma Neuro Oncol 9 314 318 10.1215/15228517-2007-002 1:CAS:528:DC%2BD2sXpt1agtr8%3D 17435180 (Pubitemid 47169664)
-
(2007)
Neuro-Oncology
, vol.9
, Issue.3
, pp. 314-318
-
-
Abrey, L.E.1
Louis, D.N.2
Paleologos, N.3
Lassman, A.B.4
Raizer, J.J.5
Mason, W.6
Finlay, J.7
MacDonald, D.R.8
DeAngelis, L.M.9
Cairncross, J.G.10
-
6
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Nov 9 (Epub ahead of print)
-
Wick W, Hartmann C, Engel C, et al.: NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 2009 Nov 9 (Epub ahead of print).
-
(2009)
J Clin Oncol
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
7
-
-
76749092080
-
Anaplastic gliomas
-
Nov 9 (Epub ahead of print). This editorial discusses two studies in anaplastic glioma, including Wick et al. [6]
-
Deangelis LM: Anaplastic gliomas. J Clin Oncol 2009 Nov 9 (Epub ahead of print). This editorial discusses two studies in anaplastic glioma, including Wick et al. [6].
-
(2009)
J Clin Oncol
-
-
Deangelis, L.M.1
-
8
-
-
51249098488
-
Anti-O6-Methylguanine-Methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: Observer variability and lack of association with patient survival impede its use as clinical biomarker
-
1:CAS:528:DC%2BD1cXht1CjtLvM 18400046
-
M Preusser RC Janzer J Felsberg, et al. 2008 Anti-O6-Methylguanine- Methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker Brain Pathol 18 520 532 1:CAS:528:DC%2BD1cXht1CjtLvM 18400046
-
(2008)
Brain Pathol
, vol.18
, pp. 520-532
-
-
Preusser, M.1
Janzer, R.C.2
Felsberg, J.3
-
9
-
-
51649117107
-
Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
-
10.1200/JCO.2007.11.5964 1:CAS:528:DC%2BD1cXhtFKisb7M 18757334
-
ME Hegi L Liu JG Herman, et al. 2008 Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity J Clin Oncol 26 4189 4199 10.1200/JCO.2007.11.5964 1:CAS:528:DC%2BD1cXhtFKisb7M 18757334
-
(2008)
J Clin Oncol
, vol.26
, pp. 4189-4199
-
-
Hegi, M.E.1
Liu, L.2
Herman, J.G.3
-
10
-
-
43749094544
-
MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients
-
10.1200/JCO.2007.14.8163 18445844
-
AA Brandes E Franceschi A Tosoni, et al. 2008 MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients J Clin Oncol 26 2192 2197 10.1200/JCO.2007.14.8163 18445844
-
(2008)
J Clin Oncol
, vol.26
, pp. 2192-2197
-
-
Brandes, A.A.1
Franceschi, E.2
Tosoni, A.3
-
11
-
-
67650494394
-
Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression
-
10.1007/s11060-009-9809-4 1:CAS:528:DC%2BD1MXotFWhsLs%3D 19221865
-
ER Gerstner MB McNamara AD Norden, et al. 2009 Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression J Neurooncol 94 97 101 10.1007/s11060-009-9809-4 1:CAS:528:DC%2BD1MXotFWhsLs%3D 19221865
-
(2009)
J Neurooncol
, vol.94
, pp. 97-101
-
-
Gerstner, E.R.1
McNamara, M.B.2
Norden, A.D.3
-
12
-
-
42649106522
-
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas
-
This is an excellent overview of pseudoprogression in GBM
-
Brandsma D, Stalpers L, Taal W, et al.: (2008). Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas. Lancet Oncol 2008, 9:453-461. This is an excellent overview of pseudoprogression in GBM.
-
(2008)
Lancet Oncol
, vol.9
, pp. 453-461
-
-
Brandsma, D.1
Stalpers, L.2
Taal, W.3
-
13
-
-
5344234474
-
How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial
-
1:STN:280:DC%2BD2crgvVWntg%3D%3D 15477552
-
AA Brandes A Tosoni P Amista, et al. 2004 How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial Neurology 63 1281 1284 1:STN:280:DC%2BD2crgvVWntg%3D%3D 15477552
-
(2004)
Neurology
, vol.63
, pp. 1281-1284
-
-
Brandes, A.A.1
Tosoni, A.2
Amista, P.3
-
14
-
-
61449171080
-
New (alternative) temozolomide regimens for the treatment of glioma
-
10.1215/15228517-2008-078 1:CAS:528:DC%2BD1MXjtFKntr8%3D 18772354
-
W Wick M Platten M Weller 2009 New (alternative) temozolomide regimens for the treatment of glioma Neuro Oncol 11 69 79 10.1215/15228517-2008-078 1:CAS:528:DC%2BD1MXjtFKntr8%3D 18772354
-
(2009)
Neuro Oncol
, vol.11
, pp. 69-79
-
-
Wick, W.1
Platten, M.2
Weller, M.3
-
15
-
-
27744506881
-
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: Tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01
-
(published correction appears in Clin Cancer Res 2006, 12:322)
-
Lassman AB, Rossi MR, Raizer JJ, et al.: Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01. Clin Cancer Res 2005, 11:7841-7850 (published correction appears in Clin Cancer Res 2006, 12:322).
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7841-7850
-
-
Lassman, A.B.1
Rossi, M.R.2
Raizer, J.J.3
-
16
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
IK Mellinghoff MY Wang I Vivanco, et al. 2005 Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors N Engl J Med 353 2012 2024 10.1056/NEJMoa051918 1:CAS:528:DC%2BD2MXht1SrtrrE 16282176 (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh Rao, P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
17
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
DOI 10.1016/S0092-8674(00)80108-7
-
D Hanahan J Folkman 1996 Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 353 364 10.1016/S0092-8674(00) 80108-7 1:CAS:528:DyaK28XltVSks7s%3D 8756718 (Pubitemid 26272076)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
18
-
-
76749168215
-
Mature circulating endothelial cells are increased in cancer patients receiving anti-angiogenic therapy
-
AC Berger A Zalotoris DR Gugger JC Watson 2003 Mature circulating endothelial cells are increased in cancer patients receiving anti-angiogenic therapy J Am Coll Surgeons 197 S83 S84
-
(2003)
J Am Coll Surgeons
, vol.197
-
-
Berger, A.C.1
Zalotoris, A.2
Gugger, D.R.3
Watson, J.C.4
-
19
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
DOI 10.1200/JCO.2005.06.081
-
DJ Hicklin 2005 Ellis, LM: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis J Clin Oncol 23 1011 1027 10.1200/JCO.2005.06.081 1:CAS:528:DC%2BD2MXit1Gnsro%3D 15585754 (Pubitemid 46202320)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
20
-
-
32944482137
-
Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma [abstract 342]
-
V Stark-Vance 2005 Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma [abstract 342] Neuro Oncol 7 369
-
(2005)
Neuro Oncol
, vol.7
, pp. 369
-
-
Stark-Vance, V.1
-
21
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
10.1200/JCO.2008.16.3055 1:CAS:528:DC%2BD1MXjsVCjs7o%3D 19114704
-
TN Kreisl L Kim K Moore, et al. 2009 Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma J Clin Oncol 27 740 745 10.1200/JCO.2008.16.3055 1:CAS:528:DC%2BD1MXjsVCjs7o%3D 19114704
-
(2009)
J Clin Oncol
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
-
22
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
DOI 10.1200/JCO.2007.12.2440
-
JJ Vredenburgh A Desjardins JE Herndon 2nd, et al. 2007 Bevacizumab plus irinotecan in recurrent glioblastoma multiforme J Clin Oncol 25 4722 4729 10.1200/JCO.2007.12.2440 1:CAS:528:DC%2BD2sXhtlCgsLjF 17947719 (Pubitemid 350086473)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.30
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon II, J.E.3
Marcello, J.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
Sampson, J.10
Wagner, M.11
Bailey, L.12
Bigner, D.D.13
Friedman, A.H.14
Friedman, H.S.15
-
23
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
This is the study that led to accelerated approval by the US Food and Drug Administration of bevacizumab for recurrent GBM
-
Friedman HS, Prados MD, Wen PY, et al.: Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 2009, 27:4733-4740. This is the study that led to accelerated approval by the US Food and Drug Administration of bevacizumab for recurrent GBM.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
24
-
-
56149097812
-
Bevacizumab: News from the fast lane?
-
This excellent commentary discusses the nuances of antiangiogenic therapies and the use of irinotecan in recurrent glioma
-
Weller M, Yung WK: Bevacizumab: news from the fast lane? Neuro Oncol 2008, 10:647. This excellent commentary discusses the nuances of antiangiogenic therapies and the use of irinotecan in recurrent glioma.
-
(2008)
Neuro Oncol
, vol.10
, pp. 647
-
-
Weller, M.1
Yung, W.K.2
-
25
-
-
76749104897
-
Safety and efficacy of bevacizumab and metronomic, oral etoposide for recurrent glioblastoma patients in a phase II study
-
D Reardon A Desjardins J Vredenburgh, et al. 2008 Safety and efficacy of bevacizumab and metronomic, oral etoposide for recurrent glioblastoma patients in a phase II study Neuro Oncol 10 839
-
(2008)
Neuro Oncol
, vol.10
, pp. 839
-
-
Reardon, D.1
Desjardins, A.2
Vredenburgh, J.3
-
27
-
-
68649114787
-
Safety and efficacy of bevacizumab with hypofractionated stereotactic irradiation for recurrent malignant gliomas
-
1:CAS:528:DC%2BD1MXhtVegsLjO 19167838
-
PH Gutin FM Iwamoto K Beal, et al. 2009 Safety and efficacy of bevacizumab with hypofractionated stereotactic irradiation for recurrent malignant gliomas Int J Radiat Oncol Biol Phys 75 156 163 1:CAS:528: DC%2BD1MXhtVegsLjO 19167838
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.75
, pp. 156-163
-
-
Gutin, P.H.1
Iwamoto, F.M.2
Beal, K.3
-
28
-
-
77955351554
-
Bevacizumab in combination with radiotherapy plus concomitant and adjuvant temozolomide for newly diagnosed glioblastoma: Update progression-free survival, overall survival, and toxicity
-
ML Gruber S Raza D Gruber A Narayana 2009 Bevacizumab in combination with radiotherapy plus concomitant and adjuvant temozolomide for newly diagnosed glioblastoma: update progression-free survival, overall survival, and toxicity J Clin Oncol (Meeting Abstracts) 27 2017
-
(2009)
J Clin Oncol (Meeting Abstracts)
, vol.27
, pp. 2017
-
-
Gruber, M.L.1
Raza, S.2
Gruber, D.3
Narayana, A.4
-
29
-
-
0027294649
-
Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials
-
10.1093/jnci/85.9.704 8478956
-
WJ Curran Jr CB Scott J Horton, et al. 1993 Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials J Natl Cancer Inst 85 704 710 10.1093/jnci/85.9.704 8478956
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 704-710
-
-
Curran Jr, W.J.1
Scott, C.B.2
Horton, J.3
-
30
-
-
76649125054
-
Phase II trial of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme
-
A Lai P Nghiemphu R Green, et al. 2009 Phase II trial of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme J Clin Oncol (Meeting Abstracts) 27 2000
-
(2009)
J Clin Oncol (Meeting Abstracts)
, vol.27
, pp. 2000
-
-
Lai, A.1
Nghiemphu, P.2
Green, R.3
-
31
-
-
45249097586
-
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: Interim analysis of safety and tolerability
-
1:CAS:528:DC%2BD1cXoslWqsLo%3D 18355978
-
A Lai E Filka B McGibbon, et al. 2008 Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability Int J Radiat Oncol Biol Phys 71 1372 1380 1:CAS:528:DC%2BD1cXoslWqsLo%3D 18355978
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, pp. 1372-1380
-
-
Lai, A.1
Filka, E.2
McGibbon, B.3
-
32
-
-
33646675851
-
MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy
-
DOI 10.1212/01.wnl.0000208958.29600.87, PII 0000611420060425000029
-
WB Pope A Lai P Nghiemphu, et al. 2006 MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy Neurology 66 1258 1260 10.1212/01.wnl.0000208958.29600.87 1:CAS:528:DC%2BD28XjtFOrtLs%3D 16636248 (Pubitemid 43739717)
-
(2006)
Neurology
, vol.66
, Issue.8
, pp. 1258-1260
-
-
Pope, W.B.1
Lai, A.2
Nghiemphu, P.3
Mischel, P.4
Cloughesy, T.F.5
-
33
-
-
70350142397
-
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
-
10.1212/WNL.0b013e3181bc0184 1:CAS:528:DC%2BD1MXht1antrfK 19822869
-
FM Iwamoto LE Abrey K Beal, et al. 2009 Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma Neurology 73 1200 1206 10.1212/WNL.0b013e3181bc0184 1:CAS:528:DC%2BD1MXht1antrfK 19822869
-
(2009)
Neurology
, vol.73
, pp. 1200-1206
-
-
Iwamoto, F.M.1
Abrey, L.E.2
Beal, K.3
-
34
-
-
36048955738
-
18F] fluorothymidine positron emission tomography: A pilot study
-
DOI 10.1200/JCO.2006.10.5825
-
W Chen S Delaloye DH Silverman, et al. 2007 Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study J Clin Oncol 25 4714 4721 10.1200/JCO.2006.10.5825 1:CAS:528:DC%2BD2sXhtlCgsLjL 17947718 (Pubitemid 350086472)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.30
, pp. 4714-4721
-
-
Chen, W.1
Delaloye, S.2
Silverman, D.H.S.3
Geist, C.4
Czernin, J.5
Sayre, J.6
Satyamurthy, N.7
Pope, W.8
Lai, A.9
Phelps, M.E.10
Cloughesy, T.11
-
35
-
-
67650075305
-
Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment
-
10.1148/radiol.2521081534 19561256
-
WB Pope HJ Kim J Huo, et al. 2009 Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment Radiology 252 182 189 10.1148/radiol.2521081534 19561256
-
(2009)
Radiology
, vol.252
, pp. 182-189
-
-
Pope, W.B.1
Kim, H.J.2
Huo, J.3
-
36
-
-
67649092660
-
Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab
-
10.1215/15228517-2009-006 1:CAS:528:DC%2BD1MXhtlWht73P 19332770
-
EC Quant AD Norden J Drappatz, et al. 2009 Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab Neuro Oncol 11 550 555 10.1215/15228517-2009-006 1:CAS:528:DC%2BD1MXhtlWht73P 19332770
-
(2009)
Neuro Oncol
, vol.11
, pp. 550-555
-
-
Quant, E.C.1
Norden, A.D.2
Drappatz, J.3
-
37
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
This excellent translational study demonstrates changes in imaging and biologic parameters during treatment with the oral anti-VEGFR TKI cedirinib (AZD2171)
-
Batchelor TT, Sorensen AG, di Tomaso E, et al.: AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007, 11:83-95. This excellent translational study demonstrates changes in imaging and biologic parameters during treatment with the oral anti-VEGFR TKI cedirinib (AZD2171).
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
Di Tomaso, E.3
-
38
-
-
0033636606
-
A mechanism for modulation of cellular responses to VEGF: Activation of the integrins
-
1:CAS:528:DC%2BD3cXnvVegtbo%3D 11090623
-
TV Byzova CK Goldman N Pampori, et al. 2000 A mechanism for modulation of cellular responses to VEGF: activation of the integrins Mol Cell 6 851 860 1:CAS:528:DC%2BD3cXnvVegtbo%3D 11090623
-
(2000)
Mol Cell
, vol.6
, pp. 851-860
-
-
Byzova, T.V.1
Goldman, C.K.2
Pampori, N.3
-
39
-
-
61849092563
-
Cooperation between integrin alpha5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity
-
10.1182/blood-2008-05-160671 1:CAS:528:DC%2BD1MXisV2hs74%3D 19036703
-
S Choi SA Lee TK Kwak, et al. 2009 Cooperation between integrin alpha5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity Blood 113 1845 1855 10.1182/blood-2008-05-160671 1:CAS:528:DC%2BD1MXisV2hs74%3D 19036703
-
(2009)
Blood
, vol.113
, pp. 1845-1855
-
-
Choi, S.1
Lee, S.A.2
Kwak, T.K.3
-
40
-
-
0027451706
-
The extracellular matrix as a cell survival factor
-
1:CAS:528:DyaK2cXhtlSrsbo%3D 8257797
-
JE Meredith Jr B Fazeli MA Schwartz 1993 The extracellular matrix as a cell survival factor Mol Biol Cell 4 953 961 1:CAS:528:DyaK2cXhtlSrsbo%3D 8257797
-
(1993)
Mol Biol Cell
, vol.4
, pp. 953-961
-
-
Meredith Jr, J.E.1
Fazeli, B.2
Schwartz, M.A.3
-
41
-
-
34249087162
-
Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma
-
DOI 10.1200/JCO.2006.06.6514
-
LB Nabors T Mikkelsen SS Rosenfeld, et al. 2007 Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma J Clin Oncol 25 1651 1657 10.1200/JCO.2006.06.6514 1:CAS:528:DC%2BD2sXlvFyktLY%3D 17470857 (Pubitemid 46797943)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.13
, pp. 1651-1657
-
-
Nabors, L.B.1
Mikkelsen, T.2
Rosenfeld, S.S.3
Hochberg, F.4
Akella, N.S.5
Fisher, J.D.6
Cloud, G.A.7
Zhang, Y.8
Carson, K.9
Wittemer, S.M.10
Colevas, A.D.11
Grossman, S.A.12
-
42
-
-
57149108506
-
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
-
10.1200/JCO.2008.16.7510 1:CAS:528:DC%2BD1MXmsVSrsw%3D%3D 18981465
-
DA Reardon KL Fink T Mikkelsen, et al. 2008 Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme J Clin Oncol 26 5610 5617 10.1200/JCO.2008.16. 7510 1:CAS:528:DC%2BD1MXmsVSrsw%3D%3D 18981465
-
(2008)
J Clin Oncol
, vol.26
, pp. 5610-5617
-
-
Reardon, D.A.1
Fink, K.L.2
Mikkelsen, T.3
-
43
-
-
56749119313
-
Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM)
-
(Meeting Abstracts)
-
Stupp R, Goldbrunner R, Neyns B, et al.: (2007). Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM). J Clin Oncol (Meeting Abstracts) 2007, 25:2000.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2000
-
-
Stupp, R.1
Goldbrunner, R.2
Neyns, B.3
-
44
-
-
70249128040
-
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: A multicenter phase II trial
-
10.1200/JCO.2008.21.6895 1:CAS:528:DC%2BD1MXhtF2jtLrI 19636006
-
SA Grossman X Ye M Chamberlain, et al. 2009 Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial J Clin Oncol 27 4155 4161 10.1200/JCO.2008.21.6895 1:CAS:528:DC%2BD1MXhtF2jtLrI 19636006
-
(2009)
J Clin Oncol
, vol.27
, pp. 4155-4161
-
-
Grossman, S.A.1
Ye, X.2
Chamberlain, M.3
-
45
-
-
57349153494
-
A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: A North American Brain Tumor Consortium (NABTC01-05)
-
10.1007/s11060-008-9693-3 1:CAS:528:DC%2BD1MXjvFeiuw%3D%3D 18797818
-
N Butowski SM Chang L Junck, et al. 2009 A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05) J Neurooncol 91 175 182 10.1007/s11060-008-9693-3 1:CAS:528:DC%2BD1MXjvFeiuw%3D%3D 18797818
-
(2009)
J Neurooncol
, vol.91
, pp. 175-182
-
-
Butowski, N.1
Chang, S.M.2
Junck, L.3
-
46
-
-
76749141046
-
New Approaches to Brain Tumor Therapy: A CNS Consortium: A phase II study of chemoradiation followed by adjuvant temozolomide and poly-ICLC in patients with newly diagnosed glioblastoma: 12- and 18-month survival data (NABTT 0501)
-
MR Rosenfeld M Chamberlain SA Grossman, et al. 2009 New Approaches to Brain Tumor Therapy: A CNS Consortium: A phase II study of chemoradiation followed by adjuvant temozolomide and poly-ICLC in patients with newly diagnosed glioblastoma: 12- and 18-month survival data (NABTT 0501) J Clin Oncol (Meeting Abstracts) 27 2002
-
(2009)
J Clin Oncol (Meeting Abstracts)
, vol.27
, pp. 2002
-
-
Rosenfeld, M.R.1
Chamberlain, M.2
Grossman, S.A.3
-
47
-
-
48649096955
-
Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients
-
10.1158/0008-5472.CAN-07-5973 1:CAS:528:DC%2BD1cXovVCntrg%3D 18632651
-
CJ Wheeler KL Black G Liu, et al. 2008 Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients Cancer Res 68 5955 5964 10.1158/0008-5472.CAN-07-5973 1:CAS:528:DC%2BD1cXovVCntrg%3D 18632651
-
(2008)
Cancer Res
, vol.68
, pp. 5955-5964
-
-
Wheeler, C.J.1
Black, K.L.2
Liu, G.3
-
48
-
-
76749110470
-
Epidermal growth factor receptor variant III (EGFRvIII) vaccine (CDX-110) in GBM
-
(Meeting Abstracts)
-
Heimberger AB, Archer GE, Mitchell DA, et al.: (2009). Epidermal growth factor receptor variant III (EGFRvIII) vaccine (CDX-110) in GBM. J Clin Oncol (Meeting Abstracts) 2009, 27:2021.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2021
-
-
Heimberger, A.B.1
Archer, G.E.2
Mitchell, D.A.3
-
49
-
-
67649974030
-
End point assessment in gliomas: Novel treatments limit usefulness of classical Macdonald's criteria
-
10.1200/JCO.2009.22.4998 19451418
-
MJ van den Bent MA Vogelbaum PY Wen, et al. 2009 End point assessment in gliomas: novel treatments limit usefulness of classical Macdonald's criteria J Clin Oncol 27 2905 2908 10.1200/JCO.2009.22.4998 19451418
-
(2009)
J Clin Oncol
, vol.27
, pp. 2905-2908
-
-
Van Den Bent, M.J.1
Vogelbaum, M.A.2
Wen, P.Y.3
-
50
-
-
76749169999
-
Current survival statistics for patients with newly diagnosed glioblastoma treated with radiation and temozolomide on research studies in the United States
-
[abstract] This meeting abstract provides an interesting analysis of the survival statistics in recently presented trials for newly diagnosed glioblastoma
-
Grossman SA, Ye X, Piantadosi S, et al.: Current survival statistics for patients with newly diagnosed glioblastoma treated with radiation and temozolomide on research studies in the United States [abstract]. J Clin Oncol 2009, 27:2003. This meeting abstract provides an interesting analysis of the survival statistics in recently presented trials for newly diagnosed glioblastoma.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2003
-
-
Grossman, S.A.1
Ye, X.2
Piantadosi, S.3
|