Blockade of RyRs in the ER attenuates 6-OHDA-induced calcium overload, cellular hypo-excitability and apoptosis in dopaminergic neurons

Frontiers in Cellular Neuroscience

Volumn 11, Issue , 2017, Pages

  Huang, Lu ^a   Xue, Ying ^a   Feng, Dayun ^a   Yang, Ruixin ^a   Nie, Tiejian ^a   Zhu, Gang ^a   Tao, Kai ^a   Gao, Guodong ^a   Yang, Qian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

6 hydroxydopamine; Calcium; ER stress; Inositol 1,4,5 triphosphate receptors; Parkinson s disease

Indexed keywords

OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL VIABILITY; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENDOPLASMIC RETICULUM STRESS; MITOCHONDRION; MTT ASSAY; NERVE CELL EXCITABILITY; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; SPIKE WAVE; TUNEL ASSAY; WESTERN BLOTTING; WHOLE CELL PATCH CLAMP;

EID: 85015646151     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2017.00052     Document Type: Article

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