Knockdown of STIM1 inhibits 6-hydroxydopamine-induced oxidative stress through attenuating calcium-dependent ER stress and mitochondrial dysfunction in undifferentiated PC12 cells

Free Radical Research

Volumn 48, Issue 7, 2014, Pages 758-768

  Li, B ^a   Xiao, L ^b   Wang, Z Y ^a   Zheng, P S ^a,c  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b XI'AN HONGHUI HOSPITAL   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

ER stress; Mitochondrial dysfunction; Reactive oxygen species; STIM1; Store operated calcium entry

Indexed keywords

ANTIOXIDANT; CALCIUM; CASPASE 12; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STROMAL INTERACTION MOLECULE 1; MEMBRANE PROTEIN; STIM1 PROTEIN, RAT;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL DEGENERATION; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PC12 CELL LINE; PROTEIN EXPRESSION; RECEPTOR POTENTIAL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DEFICIENCY; DRUG EFFECTS; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; ENDOPLASMIC RETICULUM; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; OXIDOPAMINE; PC12 CELLS; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84902144548     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2014.905687     Document Type: Article

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