Imaging Calcium Sparks in Cardiac Myocytes

Methods in Molecular Biology

Volumn 689, Issue , 2011, Pages 205-214

  Guatimosim, Silvia ^a   Guatimosim, Cristina ^a   Song, Long Sheng ^b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

calcium indicators; Calcium sparks; confocal microscopy; fluorescence; ventricular myocytes

Indexed keywords

ANILINE DERIVATIVE; FLUO 4; FLUORESCENT DYE; XANTHENE DERIVATIVE;

ARTICLE; CALCIUM SIGNALING; CONFOCAL MICROSCOPY; CYTOLOGY; HEART MUSCLE CELL; METHODOLOGY; MUSCLE CONTRACTION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANILINE COMPOUNDS; CALCIUM SIGNALING; FLUORESCENT DYES; MICROSCOPY, CONFOCAL; MUSCLE CONTRACTION; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION; XANTHENES;

MLCS; MLOWN;

EID: 79953154193     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60761-950-5_12     Document Type: Chapter

References (28)

1. Bers, D. M., (2002) Cardiac excitation-contraction coupling. Nature 415, 198–205.
2. 2+ )](i) transient. J Mol Cell Cardiol 34, 941–950.
3. Allen, D. G., Blinks, J. R. (1978) Calcium transients in aequorin-injected frog cardiac muscle. Nature 273, 509–513.
4. Wier, W. G. (1980) Calcium transients during excitation-contraction coupling in mammalian heart: aequorin signals of canine Purk-inje fibers. Science 207, 1085–1087.
5. Minta, A., Kao, J. P., Tsien, R. Y. (1989) Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chro-mophores. J Biol Chem 264, 8171–8178.
6. i in single heart cells revealed by fura-2. Science 235, 325–328.
7. Cheng, H., Lederer, W. J., Cannell, M. B. (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262, 740–744.
8. Klein, M. G., Cheng, H., Santana, L. F., Jiang, Y. H., Lederer, W. J., Schneider, M. F. (1996) Two mechanisms of quantized calcium release in skeletal muscle. Nature 379, 455–458.
9. Tsugorka, A., Rios, E., Blatter, L. A. (1995) Imaging elementary events of calcium release in skeletal muscle cells. Science 269, 1723–1726.
10. Wang, X., Weisleder, N., Collet, C., et al. (2005) Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle. Nat Cell Biol 7, 525–530.
11. Nelson, M. T., Cheng, H., Rubart, M., et al. (1995) Relaxation of arterial smooth muscle by calcium sparks. Science 270, 633–637.
12. 2+ sparks and secretion in dorsal root ganglion neurons. Proc Natl Acad Sci USA 102, 12259–12264.
13. Wei, C., Wang, X., Chen, M., Ouyang, K., Song, L. S., Cheng, H. (2009) Calcium flickers steer cell migration. Nature 457, 901–905.
14. Cheng, H., Lederer, W. J. (2008) Calcium sparks. Physiol Rev 88, 1491–1545.
15. i during excitation-contraction coupling in cardiac myocytes. Biophys J 67, 1942–1956.
16. Cannell, M. B., Cheng, H., Lederer, W. J. (1995) The control of calcium release in heart muscle. Science 268, 1045–1049.
17. 2+ ) release units and couplons in skeletal and cardiac muscles. Biophys J 77, 1528–1539.
18. Lopez-Lopez, J. R., Shacklock, P. S., Balke, C. W., Wier, W. G. (1995) Local calcium transients triggered by single L-type calcium channel currents in cardiac cells. Science 268, 1042–1045.
19. 2+ channels and ryanodine receptors in heart cells. Nature 410, 592–596.
20. Takahashi, A., Camacho, P., Lechleiter, J. D., Herman, B. (1999) Measurement of intracellular calcium. Physiol Rev 79, 1089–1125.
21. 2+ ) current. Am J Physiol Cell Physiol 280, C1327–C1339.
22. Mitcheson, J. S., Hancox, J. C., Levi, A. J. (1998) Cultured adult cardiac myocytes: future applications, culture methods, morphological and electrophysiological properties. Cardiovasc Res 39, 280–300.
23. Mitra, R., Morad, M. (1985) A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am J Physiol 249, H1056–H1060.
24. Cheng, H., Song, L. S., Shirokova, N., et al. (1999) Amplitude distribution of calcium sparks in confocal images: theory and studies with an automatic detection method. Biophys J 76, 606–617.
25. Dias-Peixoto, M. F., Santos, R. A., Gomes, E. R., et al. (2008) Molecular mechanisms involved in the angiotensin-(1–7)/Mas signaling pathway in cardiomyocytes. Hypertension 52, 542–548.
26. Song, L. S., Sobie, E. A., McCulle, S., Lederer, W. J., Balke, C. W., Cheng, H. (2006) Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci USA 103, 4305–4310.
27. 2+ ) channel. Circ Res 90, 174–181.
28. 2+ signaling in severe but compensated canine left ventricular hypertrophy. Circ Res 97, 457–464.