Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro

Journal of Infection

Volumn 74, Issue 6, 2017, Pages 599-608

  Nel, Jan G ^a,b   Durandt, Chrisna ^a   Theron, Annette J ^a   Tintinger, Gregory R ^a   Pool, Roger ^a,b   Richards, Guy A ^c,d   Mitchell, Timothy J ^e   Feldman, Charles ^c   Anderson, Ronald ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Calcium; P selectin (CD62P); Platelet activating factor; Pneumolysin; Severe pneumococcal disease

Indexed keywords

1 AMINO 3 CYCLOPROPYLAMINO 7 (4 ISOPROPYLBENZYL) 7H PYRROLO[3,2 F]QUINAZOLINE; CALCIMYCIN; INDOMETACIN; PADGEM PROTEIN; PNEUMOLYSIN; PROTEINASE ACTIVATED RECEPTOR 1; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE A2; BACTERIAL PROTEIN; CARRIER PROTEIN; KIAA0101 PROTEIN, HUMAN; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; RECOMBINANT PROTEIN; SELP PROTEIN, HUMAN; STREPTOLYSIN;

ADULT; ARTICLE; CALCIUM DEPLETION; CELL AGGREGATION; CELL FUNCTION; CELL INTERACTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUTROPHIL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; THROMBOCYTE; UPREGULATION; BIOSYNTHESIS; CELL SURVIVAL; CHEMISTRY; GENETICS; LEUKOCYTE ACTIVATION; PHYSIOLOGY; STREPTOCOCCUS PNEUMONIAE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

BACTERIAL PROTEINS; BLOOD PLATELETS; CARRIER PROTEINS; CELL AGGREGATION; CELL SURVIVAL; HUMANS; NEUTROPHIL ACTIVATION; NEUTROPHILS; P-SELECTIN; PLATELET ACTIVATION; PLATELET AGGREGATION; RECOMBINANT PROTEINS; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS; THROMBOXANE A2;

EID: 85015412029     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2017.02.010     Document Type: Article

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