Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission

Journal of Neuroimmunology

Volumn 306, Issue , 2017, Pages 46-52

  Park, Junghyung ^a   Min, Ju Sik ^a,b   Chae, Unbin ^a   Lee, Joon Yeop ^a,c   Song, Kyung Sik ^a   Lee, Hyun Shik ^a   Lee, Hong Jun ^d   Lee, Sang Rae ^b   Lee, Dong Seok ^a  

^a Kyungpook National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c National Development Institute of Korea Medicine   (South Korea)

^d Chung Ang University College of Medicine   (South Korea)

Author keywords

Drp1; Inflammation; Microglia; Mitochondrial dynamics; Oleuropein; ROS

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; OLEUROPEIN; PHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; ANTIINFLAMMATORY AGENT; COLLAPSIN RESPONSE MEDIATOR PROTEIN-2; FLUORESCENT PROTEIN 583; IRIDOID; MESSENGER RNA; NERVE PROTEIN; PHOTOPROTEIN; SIGNAL PEPTIDE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CELL VIABILITY; CONTROLLED STUDY; FRAXINUS; FRAXINUS RHYNCHOPHYLLA; IMMUNOCYTOCHEMISTRY; INFLAMMATION; KOREA; MICROGLIA; MITOCHONDRION; NONHUMAN; OLIVE; PLANT LEAF; PLANT STEM; PROTEIN DEPHOSPHORYLATION; PROTEIN ISOLATION; RNA ISOLATION; WESTERN BLOTTING; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; METABOLISM; MITOCHONDRIAL DYNAMICS; MOUSE; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE, TRANSFORMED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; IRIDOIDS; LIPOPOLYSACCHARIDES; LUMINESCENT PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; NERVE TISSUE PROTEINS; NITRIC OXIDE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRANSDUCTION, GENETIC;

EID: 85015400482     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2017.02.019     Document Type: Article

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