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Volumn 73, Issue 1, 2010, Pages 129-138

Real-time in vivo bioluminescence imaging of lentiviral vector-mediated gene transfer in mouse testis

Author keywords

Green fluorescence protein; In vivo bioluminescence imaging; In vivo gene transfer; Lentiviral vector; Testis

Indexed keywords

FIREFLY LUCIFERASE; GREEN FLUORESCENT PROTEIN;

EID: 70450265376     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2009.07.028     Document Type: Article
Times cited : (33)

References (51)
  • 1
    • 0018647190 scopus 로고
    • Hormonal regulation of Sertoli cell differentiation
    • Chemes H.E., Dym M., and Ra H.G.M. Hormonal regulation of Sertoli cell differentiation. Biol Reprod 21 (1979) 251-262
    • (1979) Biol Reprod , vol.21 , pp. 251-262
    • Chemes, H.E.1    Dym, M.2    Ra, H.G.M.3
  • 2
    • 0034892625 scopus 로고    scopus 로고
    • Differentiation of the adult Leydig cell population in the postnatal testis
    • Chamindrani Mendis-Handagama S.M.L., and Siril Ariyaratne H.B. Differentiation of the adult Leydig cell population in the postnatal testis. Biol Reprod 65 (2001) 660-671
    • (2001) Biol Reprod , vol.65 , pp. 660-671
    • Chamindrani Mendis-Handagama, S.M.L.1    Siril Ariyaratne, H.B.2
  • 3
    • 0038452372 scopus 로고    scopus 로고
    • Leydig cell-specific expression of DAX1 improves fertility of the Dax1-deficient mouse
    • Meeks J.J., Russell T.A., Jeffs B., Huhtaniemi I., Weiss J., and Jameson J.L. Leydig cell-specific expression of DAX1 improves fertility of the Dax1-deficient mouse. Biol Reprod 69 (2003) 154-160
    • (2003) Biol Reprod , vol.69 , pp. 154-160
    • Meeks, J.J.1    Russell, T.A.2    Jeffs, B.3    Huhtaniemi, I.4    Weiss, J.5    Jameson, J.L.6
  • 4
    • 0037371398 scopus 로고    scopus 로고
    • Restoration of spermatogenesis in infertile mice by Sertoli cell transplantation
    • Shinohara T., Orwig K.E., Avarbock M.R., and Brinster R.L. Restoration of spermatogenesis in infertile mice by Sertoli cell transplantation. Biol Reprod 68 (2003) 1064-1071
    • (2003) Biol Reprod , vol.68 , pp. 1064-1071
    • Shinohara, T.1    Orwig, K.E.2    Avarbock, M.R.3    Brinster, R.L.4
  • 6
    • 79961178014 scopus 로고    scopus 로고
    • In vivo gene transfer into testis and sperm: developments and future application
    • Coward K., Kubota H., and Parrington J. In vivo gene transfer into testis and sperm: developments and future application. J Systems Biol Reprod Med 53 (2007) 187-197
    • (2007) J Systems Biol Reprod Med , vol.53 , pp. 187-197
    • Coward, K.1    Kubota, H.2    Parrington, J.3
  • 7
    • 0030931963 scopus 로고    scopus 로고
    • Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector
    • Miyoshi H., Takahashi M., Gage F.H., and Verma I.M. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A 94 (1997) 10319-10323
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 10319-10323
    • Miyoshi, H.1    Takahashi, M.2    Gage, F.H.3    Verma, I.M.4
  • 8
    • 33746883603 scopus 로고    scopus 로고
    • Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging
    • Deroose C.M., Reumers V., Gijsbers R., Bormans G., Debyser Z., Mortelmans L., and Baekelandt V. Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging. Mol Ther 14 (2006) 423-431
    • (2006) Mol Ther , vol.14 , pp. 423-431
    • Deroose, C.M.1    Reumers, V.2    Gijsbers, R.3    Bormans, G.4    Debyser, Z.5    Mortelmans, L.6    Baekelandt, V.7
  • 9
    • 34247624145 scopus 로고    scopus 로고
    • Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo
    • Liu Y., Okada T., Nomoto T., Ke X., Kume A., Ozawa K., and Xiao S. Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo. Exp Mol Med 39 (2007) 170-175
    • (2007) Exp Mol Med , vol.39 , pp. 170-175
    • Liu, Y.1    Okada, T.2    Nomoto, T.3    Ke, X.4    Kume, A.5    Ozawa, K.6    Xiao, S.7
  • 10
    • 0031049602 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer to rat testis in vivo
    • Blanchard K.T., and Boekelheide K. Adenovirus-mediated gene transfer to rat testis in vivo. Biol Reprod 56 (1997) 495-500
    • (1997) Biol Reprod , vol.56 , pp. 495-500
    • Blanchard, K.T.1    Boekelheide, K.2
  • 11
    • 0037022340 scopus 로고    scopus 로고
    • Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice
    • Kanatsu-Shinohara M., Ogura A., Ikegawa M., Inoue K., Ogonuki N., Tashiro K., et al. Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. Proc Natl Acad Sci U S A 99 (2002) 1383-1388
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1383-1388
    • Kanatsu-Shinohara, M.1    Ogura, A.2    Ikegawa, M.3    Inoue, K.4    Ogonuki, N.5    Tashiro, K.6
  • 12
    • 34447125674 scopus 로고    scopus 로고
    • A novel way of therapeutic angiogenesis using an adeno-associated virus-mediated angiogenin gene transfer
    • Cho Y.H., Park H., Cho E.S., Kim W.J., Kang B.S., Park B.Y., et al. A novel way of therapeutic angiogenesis using an adeno-associated virus-mediated angiogenin gene transfer. Exp Mol Med 39 (2007) 412-418
    • (2007) Exp Mol Med , vol.39 , pp. 412-418
    • Cho, Y.H.1    Park, H.2    Cho, E.S.3    Kim, W.J.4    Kang, B.S.5    Park, B.Y.6
  • 13
    • 43549083897 scopus 로고    scopus 로고
    • No evidence of germ line transmission by adenovirus mediated gene transfer to mouse testes
    • Kojima Y., Hayashi Y., Jurokawa S., Mizuno K., Sasaki S., and Kohri K. No evidence of germ line transmission by adenovirus mediated gene transfer to mouse testes. Fertil Steril 89 (2007) 1448-1454
    • (2007) Fertil Steril , vol.89 , pp. 1448-1454
    • Kojima, Y.1    Hayashi, Y.2    Jurokawa, S.3    Mizuno, K.4    Sasaki, S.5    Kohri, K.6
  • 14
    • 4544309658 scopus 로고    scopus 로고
    • Transgenic mice produced by retroviral transduction of male germ line stem cells in vivo
    • Kanatsu-Shinohara M., Toyokuni S., and Shinohara T. Transgenic mice produced by retroviral transduction of male germ line stem cells in vivo. Biol Reprod 71 (2004) 1202-1207
    • (2004) Biol Reprod , vol.71 , pp. 1202-1207
    • Kanatsu-Shinohara, M.1    Toyokuni, S.2    Shinohara, T.3
  • 15
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy-promises, problems and prospects
    • Verma I.M., and Somia N. Gene therapy-promises, problems and prospects. Nature 389 (1997) 239-242
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 16
    • 0027376309 scopus 로고
    • A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
    • Bukrinsky M.I., Haggerty S., Dempsey M.P., Sharova N., Adzhubei A., Spitz L., et al. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature 365 (1993) 666-669
    • (1993) Nature , vol.365 , pp. 666-669
    • Bukrinsky, M.I.1    Haggerty, S.2    Dempsey, M.P.3    Sharova, N.4    Adzhubei, A.5    Spitz, L.6
  • 17
    • 38449087311 scopus 로고    scopus 로고
    • In vivo gene transfer into the testis by electroporation and viral infection-a novel way to study testis and sperm function
    • Parrington J., Coward K., Hibbitt O., Kubota H., Young C., McIlhinney J., and Jones O. In vivo gene transfer into the testis by electroporation and viral infection-a novel way to study testis and sperm function. Soc Reprod Fertil Suppl 65 (2007) 469-474
    • (2007) Soc Reprod Fertil Suppl , vol.65 , pp. 469-474
    • Parrington, J.1    Coward, K.2    Hibbitt, O.3    Kubota, H.4    Young, C.5    McIlhinney, J.6    Jones, O.7
  • 18
    • 30344441833 scopus 로고    scopus 로고
    • In vivo gene transfer by electroporation allows expression of a fluorescent transgene in hamster testis and epididymal sperm and has no adverse effects upon testicular integrity or sperm quality
    • Hibbitt O., Coward K., Kubota H., Prathalingham N., Holt W., Kohri K., and Parrington J. In vivo gene transfer by electroporation allows expression of a fluorescent transgene in hamster testis and epididymal sperm and has no adverse effects upon testicular integrity or sperm quality. Biol Reprod 74 (2006) 95-101
    • (2006) Biol Reprod , vol.74 , pp. 95-101
    • Hibbitt, O.1    Coward, K.2    Kubota, H.3    Prathalingham, N.4    Holt, W.5    Kohri, K.6    Parrington, J.7
  • 19
    • 0034005650 scopus 로고    scopus 로고
    • Use of reporter genes for optical measurements of neoplastic disease in vivo
    • Contag C.H., Jenkins D., Contag P.R., and Negrin R.S. Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia 2 (2000) 41-52
    • (2000) Neoplasia , vol.2 , pp. 41-52
    • Contag, C.H.1    Jenkins, D.2    Contag, P.R.3    Negrin, R.S.4
  • 20
    • 13844255010 scopus 로고    scopus 로고
    • Bioluminescence imaging in living organisms
    • Welsh D.K., and Kay S.A. Bioluminescence imaging in living organisms. Curr Opin Cell Biol 16 (2005) 73-78
    • (2005) Curr Opin Cell Biol , vol.16 , pp. 73-78
    • Welsh, D.K.1    Kay, S.A.2
  • 21
    • 9144243915 scopus 로고    scopus 로고
    • Fibered confocal fluorescence microscopy (Cell-viZio™) facilitates extended imaging in the field of microcirculation: a comparison with intravital microscopy
    • Laemmel E., Genet M., Le Goualher G., Perchant A., Le Gargasson J.F., and Vicaut E. Fibered confocal fluorescence microscopy (Cell-viZio™) facilitates extended imaging in the field of microcirculation: a comparison with intravital microscopy. J Vasc Res 41 (2004) 400-411
    • (2004) J Vasc Res , vol.41 , pp. 400-411
    • Laemmel, E.1    Genet, M.2    Le Goualher, G.3    Perchant, A.4    Le Gargasson, J.F.5    Vicaut, E.6
  • 22
    • 33746052458 scopus 로고    scopus 로고
    • In vivo imaging of green fluorescent protein-expressing cells in transgenic animals using fibred confocal fluorescence microscopy
    • Al-Gubory K.H., and Houdebine L.M. In vivo imaging of green fluorescent protein-expressing cells in transgenic animals using fibred confocal fluorescence microscopy. Eur J Cell Biol 85 (2006) 837-845
    • (2006) Eur J Cell Biol , vol.85 , pp. 837-845
    • Al-Gubory, K.H.1    Houdebine, L.M.2
  • 23
    • 33750502863 scopus 로고    scopus 로고
    • Live imaging of neural structure and function by fibred fluorescence microscopy
    • Vincent P., Maskos U., Charvet I., Bourgeais L., Stoppini L., Leresche N., et al. Live imaging of neural structure and function by fibred fluorescence microscopy. EMBO Rep 7 (2006) 1154-1161
    • (2006) EMBO Rep , vol.7 , pp. 1154-1161
    • Vincent, P.1    Maskos, U.2    Charvet, I.3    Bourgeais, L.4    Stoppini, L.5    Leresche, N.6
  • 24
    • 27644526205 scopus 로고    scopus 로고
    • In vivo imaging of migrating neurons in the mammalian forebrain
    • Davenne M., Custody C., Charneau P., and Lledo P.M. In vivo imaging of migrating neurons in the mammalian forebrain. Chem Senses 30 (2005) 115-116
    • (2005) Chem Senses , vol.30 , pp. 115-116
    • Davenne, M.1    Custody, C.2    Charneau, P.3    Lledo, P.M.4
  • 25
    • 18044366012 scopus 로고    scopus 로고
    • Mutations in squirrel monkey glucocorticoid receptor impair nuclear translocation
    • Her S., Patel P.D., Schatzberg A.F., and Lyons D.M. Mutations in squirrel monkey glucocorticoid receptor impair nuclear translocation. J Steroid Biochem Mol Biol 94 (2005) 319-326
    • (2005) J Steroid Biochem Mol Biol , vol.94 , pp. 319-326
    • Her, S.1    Patel, P.D.2    Schatzberg, A.F.3    Lyons, D.M.4
  • 26
    • 0029757751 scopus 로고    scopus 로고
    • Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
    • Back N.K., Nijhuis M., Keulen W., Boucher C.A., Oude Essink B.O., van Kuilenburg A.B., et al. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J 15 (1996) 4040-4049
    • (1996) EMBO J , vol.15 , pp. 4040-4049
    • Back, N.K.1    Nijhuis, M.2    Keulen, W.3    Boucher, C.A.4    Oude Essink, B.O.5    van Kuilenburg, A.B.6
  • 27
    • 1642452660 scopus 로고    scopus 로고
    • Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
    • Nishitsuji H., Ikeda T., Miyoshi H., Ohashi T., Kannagi M., and Masuda T. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect 6 (2004) 76-85
    • (2004) Microbes Infect , vol.6 , pp. 76-85
    • Nishitsuji, H.1    Ikeda, T.2    Miyoshi, H.3    Ohashi, T.4    Kannagi, M.5    Masuda, T.6
  • 28
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia G., Singer O., and Verma I.M. Production and purification of lentiviral vectors. Nat Protoc 1 (2006) 241-245
    • (2006) Nat Protoc , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 29
  • 30
    • 0034141492 scopus 로고    scopus 로고
    • In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker
    • Yamazaki Y., Yagi T., Ozaki T., and Imoto K. In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker. J Exp Zool 286 (2000) 212-218
    • (2000) J Exp Zool , vol.286 , pp. 212-218
    • Yamazaki, Y.1    Yagi, T.2    Ozaki, T.3    Imoto, K.4
  • 31
    • 17444427633 scopus 로고    scopus 로고
    • Comparison of two methods of in vivo gene transfer by electroporation
    • Kubota H., Hayashi Y., Kubota Y., Coward K., and Parrington J. Comparison of two methods of in vivo gene transfer by electroporation. Fertil Steril 83 (2005) 1310-1318
    • (2005) Fertil Steril , vol.83 , pp. 1310-1318
    • Kubota, H.1    Hayashi, Y.2    Kubota, Y.3    Coward, K.4    Parrington, J.5
  • 32
    • 34347360705 scopus 로고    scopus 로고
    • In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma
    • Dickson P.V., Hamner B., Ng C.Y.C., Hall M.M., Zhou J., Hargrove P.W., et al. In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma. J Pediatr Surg 42 (2007) 1172-1179
    • (2007) J Pediatr Surg , vol.42 , pp. 1172-1179
    • Dickson, P.V.1    Hamner, B.2    Ng, C.Y.C.3    Hall, M.M.4    Zhou, J.5    Hargrove, P.W.6
  • 34
    • 0031796476 scopus 로고    scopus 로고
    • In vivo gene transfer to mouse spermatogenic cells by deoxyribonucleic acid injection into seminiferous tubules and subsequent electroporation
    • Yamazaki Y., Fujimoto H., Ando H., Ohyama T., Hirota Y., and Noce T. In vivo gene transfer to mouse spermatogenic cells by deoxyribonucleic acid injection into seminiferous tubules and subsequent electroporation. Biol Reprod 59 (1998) 1439-1444
    • (1998) Biol Reprod , vol.59 , pp. 1439-1444
    • Yamazaki, Y.1    Fujimoto, H.2    Ando, H.3    Ohyama, T.4    Hirota, Y.5    Noce, T.6
  • 35
    • 0034731298 scopus 로고    scopus 로고
    • In vivo transfection of testicular germ cells and transgenesis by using the mitochondrially localized jellyfish fluorescent protein gene
    • Huang Z., Tamura M., Sakurai T., Chuma S., Saito T., and Nakatsuji N. In vivo transfection of testicular germ cells and transgenesis by using the mitochondrially localized jellyfish fluorescent protein gene. FEBS Lett 487 (2000) 248-251
    • (2000) FEBS Lett , vol.487 , pp. 248-251
    • Huang, Z.1    Tamura, M.2    Sakurai, T.3    Chuma, S.4    Saito, T.5    Nakatsuji, N.6
  • 36
    • 0442323481 scopus 로고    scopus 로고
    • Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation
    • Ike A., Ohta H., Onishi M., Iguchi N., Nishimune Y., and Nozaki M. Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation. FEBS Lett 559 (2004) 159-164
    • (2004) FEBS Lett , vol.559 , pp. 159-164
    • Ike, A.1    Ohta, H.2    Onishi, M.3    Iguchi, N.4    Nishimune, Y.5    Nozaki, M.6
  • 37
    • 0142150950 scopus 로고    scopus 로고
    • Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lectiviral vectors for gene therapy
    • Ikawa M., Tanaka N., Kao W.W.Y., and Verma I.M. Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lectiviral vectors for gene therapy. Mol Ther 8 (2003) 666-673
    • (2003) Mol Ther , vol.8 , pp. 666-673
    • Ikawa, M.1    Tanaka, N.2    Kao, W.W.Y.3    Verma, I.M.4
  • 38
    • 0034242966 scopus 로고    scopus 로고
    • In vivo gene electroporation confers strong transient expression of foreign genes in the chicken testis
    • Sugihara K., Park H.M., and Muramatsu T. In vivo gene electroporation confers strong transient expression of foreign genes in the chicken testis. Poult Sci 79 (2000) 1116-1119
    • (2000) Poult Sci , vol.79 , pp. 1116-1119
    • Sugihara, K.1    Park, H.M.2    Muramatsu, T.3
  • 39
    • 0030930987 scopus 로고    scopus 로고
    • Development of a positive method for male stem cell-mediated gene transfer in mouse and pig
    • Kim J.H., Jung-Ha H.S., Lee H.T., and Chung K.S. Development of a positive method for male stem cell-mediated gene transfer in mouse and pig. Mol Reprod Dev 46 (1997) 515-526
    • (1997) Mol Reprod Dev , vol.46 , pp. 515-526
    • Kim, J.H.1    Jung-Ha, H.S.2    Lee, H.T.3    Chung, K.S.4
  • 40
    • 33644849262 scopus 로고    scopus 로고
    • Expression of a fluorescent recombinant form of sperm protein phospholipase C zeta in mouse epididymal sperm by in vivo gene transfer into the testis
    • Coward K., Kubota H., Hibbitt O., McIlhinney J., Kohri K., and Parrington J. Expression of a fluorescent recombinant form of sperm protein phospholipase C zeta in mouse epididymal sperm by in vivo gene transfer into the testis. Fertil Steril 85 (2006) 1281-1289
    • (2006) Fertil Steril , vol.85 , pp. 1281-1289
    • Coward, K.1    Kubota, H.2    Hibbitt, O.3    McIlhinney, J.4    Kohri, K.5    Parrington, J.6
  • 41
    • 0035570432 scopus 로고    scopus 로고
    • CMV-driven expression of green-fluorescent protein (GFP) in male germ cells of transgenic mice and its effect on fertility
    • Villuendas G., Gutierrez-Adan A., Jimenez A., Rojo C., Roldan E.R., and Pintado B. CMV-driven expression of green-fluorescent protein (GFP) in male germ cells of transgenic mice and its effect on fertility. Int J Androl 24 (2001) 300-305
    • (2001) Int J Androl , vol.24 , pp. 300-305
    • Villuendas, G.1    Gutierrez-Adan, A.2    Jimenez, A.3    Rojo, C.4    Roldan, E.R.5    Pintado, B.6
  • 42
    • 43749114031 scopus 로고    scopus 로고
    • Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model
    • Shah K., Hingtgen S., Kasmieh R., Figueiredo J.L., Garcia-Garcia E., Martinez-Serrano A., et al. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci 28 (2008) 4406-4413
    • (2008) J Neurosci , vol.28 , pp. 4406-4413
    • Shah, K.1    Hingtgen, S.2    Kasmieh, R.3    Figueiredo, J.L.4    Garcia-Garcia, E.5    Martinez-Serrano, A.6
  • 44
    • 0025872644 scopus 로고
    • Membrane-permeable luciferin esters for assay of firefly luciferase in live intact cells
    • Craig F.F., Simmonds A.C., Watmore D., McCapra F., and White M.R.H. Membrane-permeable luciferin esters for assay of firefly luciferase in live intact cells. Biochem J 276 (1991) 637-641
    • (1991) Biochem J , vol.276 , pp. 637-641
    • Craig, F.F.1    Simmonds, A.C.2    Watmore, D.3    McCapra, F.4    White, M.R.H.5
  • 45
    • 0034918106 scopus 로고    scopus 로고
    • In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy
    • Brown E.B., Campbell R.B., Tsuzuki Y., Xu L., Carmeliet P., Fukumura D., and Jain R.K. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med 7 (2001) 864-868
    • (2001) Nat Med , vol.7 , pp. 864-868
    • Brown, E.B.1    Campbell, R.B.2    Tsuzuki, Y.3    Xu, L.4    Carmeliet, P.5    Fukumura, D.6    Jain, R.K.7
  • 47
  • 48
    • 0026396786 scopus 로고
    • Expression of homeobox genes during spermaogenesis
    • Wolgemuth D.J., Viviano C.M., and Watrin F. Expression of homeobox genes during spermaogenesis. Ann N Y Acad Sci 637 (1991) 300-312
    • (1991) Ann N Y Acad Sci , vol.637 , pp. 300-312
    • Wolgemuth, D.J.1    Viviano, C.M.2    Watrin, F.3
  • 49
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • Naldini L., Blömer U., Gage F.H., Trono D., and Verma I.M. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 93 (1996) 11382-11388
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11382-11388
    • Naldini, L.1    Blömer, U.2    Gage, F.H.3    Trono, D.4    Verma, I.M.5
  • 50
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L., Blömer U., Gallay P., Ory D., Mulligan R., Gage F.H., et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272 (1996) 263-267
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blömer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6
  • 51
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas C.E., Ehrhardt A., and Kay M.A. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 4 (2003) 346-358
    • (2003) Nat Rev Genet , vol.4 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.