CD54-Mediated Interaction with Pro-inflammatory Macrophages Increases the Immunosuppressive Function of Human Mesenchymal Stromal Cells

Stem Cell Reports

Volumn 8, Issue 4, 2017, Pages 961-976

  Espagnolle, Nicolas ^a,b   Balguerie, Adélie ^a,b   Arnaud, Emmanuelle ^a   Sensebé, Luc ^a,b   Varin, Audrey ^a,b  

^a Institut National de la Sant é et de la Recherche Medicale   (France)

^b ETABLISSEMENT FRANÇAIS DU SANG   (France)

Author keywords

bone marrow mesenchymal stromal cells; CD54; cell therapy; functional interaction; immunosuppression; indoleamine 2,3 dioxygenase; macrophages

Indexed keywords

GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 4; PROGRAMMED DEATH 1 LIGAND 1; CALCIUM; TRANSCRIPTOME;

ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL CONTACT; CELL DIFFERENTIATION; CELL INTERACTION; CELL ISOLATION; COCULTURE; CONTROLLED STUDY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY CELL; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MACROPHAGE ACTIVATION; MESENCHYMAL STROMA CELL; MICROTUBULE ORGANIZING CENTER; PERIPHERAL BLOOD MONONUCLEAR CELL; POLARIZATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TH1 CELL; TH2 CELL; CELL COMMUNICATION; CELL CULTURE; CELLULAR IMMUNITY; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; UPREGULATION;

CALCIUM; CELL COMMUNICATION; CELLS, CULTURED; HUMANS; IMMUNE TOLERANCE; IMMUNITY, CELLULAR; IMMUNOSUPPRESSION; INTERCELLULAR ADHESION MOLECULE-1; MACROPHAGES; MESENCHYMAL STROMAL CELLS; TRANSCRIPTOME; UP-REGULATION;

EID: 85015337443     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2017.02.008     Document Type: Article

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